Outputs (8)

The potential for statins in the treatment of ovarian cancer (2013)
Journal Article

Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes. (2013)
Journal Article

Dendrimer Conjugate of [4-(Tetradecanoylamino)benzyl]phosphonic Acid (S32826) as an Autotaxin Inhibitor. (2013)
Journal Article

Autotaxin is an extracellular phospholipase D that catalyzes the hydrolysis of lysophosphatidyl choline (LPC) to bioactive lipid lysophosphatidic acid (LPA). LPA has been implicated in many pathological processes relevant to cancer, including cell mi... Read More about Dendrimer Conjugate of [4-(Tetradecanoylamino)benzyl]phosphonic Acid (S32826) as an Autotaxin Inhibitor..

AUTOTAXIN INHIBITORS AS A POTENTIAL TREATMENT FOR OVARIAN (2013)
Journal Article

Anti-cancer thymoquinone from Nigella sativa (2013)
Journal Article

Quinones and phenolic compounds are important bioactive natural products in medicinal and dietary plants [1 – 3]. For example, thymoquinone (2-isopropyl-6-methyl-1,4-benzoquinone, TQ) is the main bioactive compound from Nigella sativa (black cumin) (... Read More about Anti-cancer thymoquinone from Nigella sativa.

Chairs, bells and students – a novel method to simulate and teach molecular interactions in pharmacology (2013)
Journal Article

Background: Pharmacy education requires an understanding of the fundamental principles of molecular pharmacology. Among these, abstract concepts such as affinity, association and dissociation rates and partial agonism may be difficult to demonstrate... Read More about Chairs, bells and students – a novel method to simulate and teach molecular interactions in pharmacology.

Use of a Three-Dimensional Virtual Environment to Teach Drug-Receptor Interactions (2013)
Journal Article

Objective. To determine whether using 3-dimensional (3D) technology to teach pharmacy students about the molecular basis of the interactions between drugs and their targets is more effective than traditional lecture using 2-dimensional (2D) graphics.... Read More about Use of a Three-Dimensional Virtual Environment to Teach Drug-Receptor Interactions.

Preclinical evaluation of statins as a treatment for ovarian cancer (2013)
Journal Article

Objective To evaluate the potential for statins to treat ovarian cancer. Methods The sensitivity of 7 ovarian cancer cell lines to either statins or statins combined with either carboplatin or paclitaxel was assessed using monolayer cultures. Se... Read More about Preclinical evaluation of statins as a treatment for ovarian cancer.