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Outputs (86)

768 STAKEHOLDER CO-DESIGN OF AN EXTENDED COMMUNITY PHARMACY ROLE AND SERVICE DELIVERY MODEL FOR PROVIDING OSTEOARTHRITS CARE: THE PHARMOA MODEL (2024)
Presentation / Conference
Holden, M., Stanford, C., Simkins, J., Babatunde, O. O., White, S., O'Brien, N., …Healey, E. L. (2024, April). 768 STAKEHOLDER CO-DESIGN OF AN EXTENDED COMMUNITY PHARMACY ROLE AND SERVICE DELIVERY MODEL FOR PROVIDING OSTEOARTHRITS CARE: THE PHARMOA MODEL. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

767 EXPLORING THE POTENTIAL EXTENDED ROLE OF COMMUNITY PHARMACY IN THE MANAGEMENT OF OSTEOARTHRITIS: SURVEYS AND INTERVIEWS WITH COMMUNITY PHARMACY STAFF AND OTHER HEALTHCARE PROFESSIONALS (2024)
Presentation / Conference
Simkins, J., Holden, M., Babatunde, O. O., White, S., Nicholls, E., Long, A., …O'Brien, N. (2024, April). 767 EXPLORING THE POTENTIAL EXTENDED ROLE OF COMMUNITY PHARMACY IN THE MANAGEMENT OF OSTEOARTHRITIS: SURVEYS AND INTERVIEWS WITH COMMUNITY PHARMACY STAFF AND OTHER HEALTHCARE PROFESSIONALS. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

Protocol for a trial-based economic evaluation analysis of a complex digital health intervention including a computerised decision support tool: the iFraP intervention (2024)
Journal Article
Siciliano, M., Bathers, S., Bentley, I., Bullock, L., Cherrington, A., Clark, E., …Iglesias-Urrutia, C. (in press). Protocol for a trial-based economic evaluation analysis of a complex digital health intervention including a computerised decision support tool: the iFraP intervention. NIHR Open Research, 4(15), https://doi.org/10.3310/nihropenres.13575.1

Background Digital health interventions (DHI) are associated with significant promise. In recent years, the need to assess the value of these healthcare technologies has motivated a debate regarding the suitability of existing economic evaluation me... Read More about Protocol for a trial-based economic evaluation analysis of a complex digital health intervention including a computerised decision support tool: the iFraP intervention.

A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol (2024)
Journal Article
Bullock, L., Nicholls, E., Cherrington, A., Butler-Walley, S., Clark, E. M., Fleming, J., …Paskins, Z. (in press). A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol. NIHR Open Research, 4(14), https://doi.org/10.3310/nihropenres.13571.1

Background Good quality shared decision-making (SDM) conversations involve people with, or at risk of osteoporosis and clinicians collaborating to decide, where appropriate, which evidence-based medicines best fit the person’s life, beliefs, and val... Read More about A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol.

Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals (2024)
Journal Article
Simkins, J., Holden, M. A., Babatunde, O., White, S., Nicholls, E., Long, A., …O’Brien, N. (2024). Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals. Musculoskeletal Care, 22(1), Article e1873. https://doi.org/10.1002/msc.1873

Introduction Osteoarthritis is the commonest form of chronic joint pain, which patients often self-manage before seeking healthcare advice. Patients frequently seek advice from community pharmacies, and a recent policy has recommended integrating co... Read More about Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals.

Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA) (2024)
Journal Article
Babatunde, O. O., Cottrell, E., White, S., Chudyk, A., Healey, E. L., Edwards, J., …Holden, M. A. (in press). Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA). BMC Musculoskeletal Disorders, 25(1), Article 54. https://doi.org/10.1186/s12891-023-07105-2

Background Osteoarthritis is a common, painful and disabling long-term condition. Delivery of high-quality guideline-informed osteoarthritis care that successfully promotes and maintains supported self-management is imperative. However, osteoarthrit... Read More about Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA).

Bone health assessment in adults with fragility fracture risk factors between 2002-2014: a retrospective cohort study. (2023)
Journal Article
Pradhan, A., Nicholls, E., Edwards, J., Welsh, V., & Paskins, Z. (2023). Bone health assessment in adults with fragility fracture risk factors between 2002-2014: a retrospective cohort study. British Journal of General Practice Open (BJGP Open), 8(1), Article 0084. https://doi.org/10.3399/BJGPO.2023.0084

Background: Lifetime risk of fragility fractures is 50% in post-menopausal women and 20% in men aged over 50 years. Identifying people at high risk facilitates early intervention and reduction of biopsychosocial morbidity associated with these fractu... Read More about Bone health assessment in adults with fragility fracture risk factors between 2002-2014: a retrospective cohort study..

Proactive review of patients taking opioid medicines for persistent pain led by pharmacists in primary care teams (PROMPPT): A feasibility study (2023)
Presentation / Conference
Ashworth, J., Cornwall, N., Harrisson, S. A., Woodcock, C., Nicholls, E., Laing, L., …Jinks, C. (2023, May). Proactive review of patients taking opioid medicines for persistent pain led by pharmacists in primary care teams (PROMPPT): A feasibility study. Presented at BPS Annual Scientific Meeting 2023, Glasgow, Scotland, UK

Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). (2023)
Journal Article
Foster, N. E., Nicholls, E., Holden, M. A., Healey, E. L., Hay, E. M., & trial team, T. B. (2023). Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). Archives of Rehabilitation Research and Clinical Translation, 5(2), Article 100266. https://doi.org/10.1016/j.arrct.2023.100266

To investigate whether knee osteoarthritis (OA) related pain and function can be improved by offering enhanced physical therapist-led exercise interventions. Three-arm prospectively designed pragmatic randomized controlled trial. General practices an... Read More about Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial)..

Thinking differently: evidence on what patients want and need in an explanation about osteoarthritis (2023)
Journal Article
Jinks, C., Campbell, L., Croft, P., Dziedzic, K., Grossman, H., Maddison, J., …Cottrell, L. (2023). Thinking differently: evidence on what patients want and need in an explanation about osteoarthritis. Osteoarthritis and Cartilage, 31(5), 711-712. https://doi.org/10.1016/j.joca.2023.02.064

Purpose: Osteoarthritis (OA) is a major cause of pain and disability worldwide. Despite this and the existence of evidence-based guidelines, many patients and professionals lack clarity about the nature of OA and effective treatment strategies. Healt... Read More about Thinking differently: evidence on what patients want and need in an explanation about osteoarthritis.

Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care (2022)
Journal Article
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., …Roddy, E. (2022). Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care. Rheumatology, 62(8), 2748-2756. https://doi.org/10.1093/rheumatology/keac706

Objective To describe factors associated with change in health-related quality of life (HRQOL) in people living with gout in primary care. Methods In a UK prospective cohort study, adults with a diagnosis of gout registered with 20 general practices... Read More about Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care.

THE SUBGROUP EFFECTS OF NON-SURGICAL AND NON-PHARMACOLOGICAL TREATMENT OF PATIENTS WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK (2022)
Journal Article
Thissen, G., van Middelkoop, M., Colaris, J., Selles, R., Dziedzic, K., Nicholls, E., & Bierma-Zeinstra, S. (2022). THE SUBGROUP EFFECTS OF NON-SURGICAL AND NON-PHARMACOLOGICAL TREATMENT OF PATIENTS WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK. Osteoarthritis and Cartilage, 30(S1), S423. https://doi.org/10.1016/j.joca.2022.02.576

THE SUBGROUP EFFECTS OF SURGICAL TREATMENT OF PATIENT WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK (2022)
Journal Article
Thissen, G., Middelkoop van, M., Colaris, J., Selles, R., Dziedzic, K., Nicholls, E., & Bierma-Zeinstra, S. (2022). THE SUBGROUP EFFECTS OF SURGICAL TREATMENT OF PATIENT WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK. Osteoarthritis and Cartilage, 30, S423. https://doi.org/10.1016/j.joca.2022.02.577

Purpose: The hand joints are frequently affected by osteoarthritis (OA) in the adult population. Patients whose pain and disability are persistent may benefit from surgical treatment. However, based on current evidence, small and moderate effect size... Read More about THE SUBGROUP EFFECTS OF SURGICAL TREATMENT OF PATIENT WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK.

Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis. (2022)
Journal Article
Dziedzic, & Nicholls. (2022). Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis. BMJ Open, e057156 - ?. https://doi.org/10.1136/bmjopen-2021-057156

INTRODUCTION: Hand osteoarthritis (OA) is a common joint disorder in the adult population. No cure for hand OA is known yet, but treatment aims to reduce symptoms. Non-surgical and non-pharmacological therapy interventions can include splinting, pati... Read More about Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis..

Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial. (2021)
Journal Article
Healey, E. L., Mallen, C. D., Chew-Graham, C. A., Nicholls, E., Lewis, M., Lawton, S. A., …Jinks, C. (2022). Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial. Family Practice, 39(4), 592–602. https://doi.org/10.1093/fampra/cmab113

Background: Multimorbidity is increasingly the norm; however, primary care remains focused on single diseases. Osteoarthritis, anxiety, and depression are frequently comorbid with other long-term conditions (LTCs), but rarely prioritized by clinician... Read More about Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial..

Clinical and cost-effectiveness of bracing in symptomatic knee osteoarthritis management: protocol for a multicentre, primary care, randomised, parallel-group, superiority trial. (2021)
Journal Article
Holden, M., Callaghan, M., Felson, D., Birrell, F., Nicholls, E., Jowett, S., …Peat, G. (2021). Clinical and cost-effectiveness of bracing in symptomatic knee osteoarthritis management: protocol for a multicentre, primary care, randomised, parallel-group, superiority trial. BMJ Open, 11(3), Article e048196. https://doi.org/10.1136/bmjopen-2020-048196

BACKGROUND: Brace effectiveness for knee osteoarthritis (OA) remains unclear and international guidelines offer conflicting recommendations. Our trial will determine the clinical and cost-effectiveness of adding knee bracing (matched to patients' cli... Read More about Clinical and cost-effectiveness of bracing in symptomatic knee osteoarthritis management: protocol for a multicentre, primary care, randomised, parallel-group, superiority trial..

Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care (2020)
Journal Article
Muller, Watson, Belcher, Mallen, Roddy, & Nicholls. (2020). Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care. Arthritis and Rheumatology, 72(11), 1928-1935. https://doi.org/10.1002/art.41476

Objective To investigate the existence of distinct classes of gout flare trajectories and compare their gout-specific, comorbid, and sociodemographic characteristics. Methods In a prospective cohort study, adults with gout who were registered wi... Read More about Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care.

P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care (2020)
Journal Article
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., …Roddy, E. (2020). P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care. Rheumatology, 59(Supplement_2), https://doi.org/10.1093/rheumatology/keaa111.137

Background Gout affects 2.5% of adults in the UK but is often poorly managed. It can impair health-related quality of life (HRQOL), yet little is known about which people with gout are at risk of worse outcomes. We investigated factors associated wi... Read More about P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care.

Relative prevalence and distribution of knee, hand and foot symptomatic osteoarthritis subtypes in an English population (2020)
Journal Article
Peat, G., Rathod-Mistry, T., Paskins, Z., Marshall, M., Thomas, M. J., Menz, H. B., …Dziedzic, K. S. (2020). Relative prevalence and distribution of knee, hand and foot symptomatic osteoarthritis subtypes in an English population. Musculoskeletal Care, 18(2), 219-224. https://doi.org/10.1002/msc.1457

In this brief report, we used data from a series of three related cohorts on pain and osteoarthritis (OA) of the knee, hand and foot, which were conducted in North Staffordshire, England. We used a common approach for sampling, data collection and co... Read More about Relative prevalence and distribution of knee, hand and foot symptomatic osteoarthritis subtypes in an English population.

Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain (2019)
Journal Article
Marshall, M., Jonsson, H., Helgadottir, G. P., Nicholls, E., Myers, H., Jansen, V., & van der Windt, D. (2019). Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain. BMC Musculoskeletal Disorders, 20, Article 484. https://doi.org/10.1186/s12891-019-2829-0

Background To determine the longitudinal construct validity of assessing hand OA progression on digital photographs over 7?years compared with progression determined from radiographs, clinical features and change in symptoms. Methods Participant... Read More about Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain.

Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis (2019)
Journal Article
Thomas, M., Yu, D., Nicholls, E., Bierma‐Zeinstra, S., Conaghan, P. G., Stoner, K. J., …Peat, G. (2020). Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis. Arthritis Care and Research, 72(12), 1687-1692. https://doi.org/10.1002/acr.24088

Objective To identify distinct recovery trajectories of acute flares of knee pain and associated participant characteristics. Methods Data were from FLARE RCT, a multicentre trial in 27 primary care centres in UK and Netherlands of three regimes... Read More about Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis.

Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study (2019)
Report
Burroughs, H., Bartlam, B., Bullock, P., Lovell, K., Ogollah, R., Ray, M., …Chew-Graham, C. (2019). Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study. NIHR

BACKGROUND:Anxiety and depression often coexist in older people. These disorders are often underdiagnosed and undertreated, and are associated with increased use of health and social care services, and raised mortality. Barriers to diagnosis include... Read More about Non-traditional support workers delivering a brief psychosocial intervention for older people with anxiety and depression: the NOTEPAD feasibility study.

Can support workers from AgeUK deliver an intervention to support older people with anxiety and depression? A qualitative evaluation. (2019)
Journal Article
Gilbody, S., Nicholls, E., Chew-Graham, C., Kingstone, T., Bartlam, B., Burroughs, H., …Waheed, W. (2019). Can support workers from AgeUK deliver an intervention to support older people with anxiety and depression? A qualitative evaluation. BMC Family Practice, 20, Article 16. https://doi.org/10.1186/s12875-019-0903-1

BACKGROUND: Anxiety and depression often co-exist. These disorders are under-diagnosed and under-treated, specifically among older people, and lead to increased use of health and social care services and raised mortality. Older people report a reluct... Read More about Can support workers from AgeUK deliver an intervention to support older people with anxiety and depression? A qualitative evaluation..

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials (2018)
Report
Hay, E., Dziedzic, K., Foster, N., Peat, G., van der Windt, D., Bartlam, B., …Croft, P. (2018). Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials. NIHR. PGfAR as project number RP-PG-0407-10386. Secretary of State for Health and Social Care

Background Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability. Objectives Th... Read More about Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study (2018)
Journal Article
Marshall, M., Peat, G., Nicholls, E., Myers, H. L., Mamas, M. A., & Van Der Windt, D. A. (in press). Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study. Scandinavian Journal of Rheumatology, 48(1), 52-63. https://doi.org/10.1080/03009742.2018.1459831

OBJECTIVE: To determine whether selected metabolic factors are associated with greater amounts of radiographic hand osteoarthritis (OA) incidence and progression. METHODS: The study identified 706 adults, aged 50-69 years, with hand pain and hand rad... Read More about Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study.

Cost-utility analysis of interventions to improve effectiveness of exercise therapy for adults with knee osteoarthritis: the BEEP trial. (2018)
Journal Article
Kigozi, J., Jowett, S., Nicholls, E., Tooth, S., Hay, E., Foster, N. E., & Holden, M. (2018). Cost-utility analysis of interventions to improve effectiveness of exercise therapy for adults with knee osteoarthritis: the BEEP trial. Rheumatology Advances in Practice, rky018 - ?. https://doi.org/10.1093/rap/rky018

Objectives: Evidence regarding the cost-effectiveness of enhancing physical therapy exercise programmes in order to improve outcomes for patients with knee OA remains unclear. This study investigates the cost-effectiveness of two enhanced physical th... Read More about Cost-utility analysis of interventions to improve effectiveness of exercise therapy for adults with knee osteoarthritis: the BEEP trial..

Longitudinal validity of using digital photographs for assessing progression of hand osteoarthritis over 7 years in community-dwelling adults (2018)
Presentation / Conference
Marshall, M., Jonsson, H., Helgadottir, G., Nicholls, E., Myers, H., Jansen, V., & Van Der Windt, D. (2018, April). Longitudinal validity of using digital photographs for assessing progression of hand osteoarthritis over 7 years in community-dwelling adults. Paper presented at 2018 OASRI World Congress on Osteoarthritis, Liverpool, UK

The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol (2017)
Journal Article
Healey, E., Jinks, C., Foster, N., Chew-Graham, Chew-Graham, C., Pincus, T., …McBeth, J. (2017). The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol. Musculoskeletal Care, 16(1), https://doi.org/10.1002/msc.1222

INTRODUCTION: This pilot trial will inform the design and methods of a future full-scale randomized controlled trial (RCT) and examine the feasibility, acceptability and fidelity of the Increasing Physical activity in Older People with chronic Pain (... Read More about The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol.

Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial (2017)
Journal Article
Jinks, C., Nicholls, E., Liddle, J., Healey, E., Evans, A., Chew-Graham, C., …Team, E. (2017). Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial. Annals of the Rheumatic Diseases, 76(S2), 1433-1433. https://doi.org/10.1136/annrheumdis-2017-eular.2473

Background Co-morbid osteoarthritis (OA), anxiety and depression are undermanaged in primary care yet have significant impact on pain, disability and outcomes of other long-term conditions (LTCs). Objectives To test the feasibility and acceptabili... Read More about Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial.

Self-management of musculoskeletal hand pain and hand problems in community-dwelling adults aged 50 years and older: results from a cross-sectional study in a UK population. (2016)
Journal Article
Myers, H., Dziedzic, K., Nicholls, E., & Croft, P. (2016). Self-management of musculoskeletal hand pain and hand problems in community-dwelling adults aged 50 years and older: results from a cross-sectional study in a UK population. BMC Musculoskeletal Disorders, 17, Article 418. https://doi.org/10.1186/s12891-016-1276-4

BACKGROUND: Musculoskeletal pain is common in adults, with the hand being frequently affected. Healthcare services have the potential to be of benefit to adults with hand pain and problems, through promotion and facilitation of self-management. METHO... Read More about Self-management of musculoskeletal hand pain and hand problems in community-dwelling adults aged 50 years and older: results from a cross-sectional study in a UK population..

An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain (2016)
Journal Article
Jowett, S., Nicholls, E., Al-Janabi, H., Keeley, T., Coast, J., & Foster, N. (2016). An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain. Health and Quality of Life Outcomes, 36 -?. https://doi.org/10.1186/s12955-016-0430-x

BACKGROUND: The ICECAP measures potentially offer a broader assessment of quality of life and well-being, in comparison to measures routinely used in economic evaluation, such as the EQ-5D-3 L. This broader assessment may allow measurement of the ful... Read More about An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain.

Improving the care of people with long-term conditions in primary care: (2015)
Journal Article
Healey, E. L., Jinks, C., Tan, V. A., Chew-Graham, C. A., Lawton, S. A., Nicholls, E., …Mallen, C. D. (2015). Improving the care of people with long-term conditions in primary care:. Journal of Comorbidity, 2015(5), 135-149. https://doi.org/10.15256/joc.2015.5.60

Background Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused on... Read More about Improving the care of people with long-term conditions in primary care:.

A longitudinal assessment of the responsiveness of the ICECAP-A in a randomised controlled trial of a knee pain intervention (2015)
Journal Article
Keeley, T., Al-Janabi, H., Nicholls, E., Foster, N., Jowett, S., & Coast, J. (2015). A longitudinal assessment of the responsiveness of the ICECAP-A in a randomised controlled trial of a knee pain intervention. Quality of Life Research, 2319 - 2331. https://doi.org/10.1007/s11136-015-0980-0

PURPOSE: The ICECAP-A is a simple measure of capability well-being for use with the adult population. The descriptive system is made up of five key attributes: Stability, Attachment, Autonomy, Achievement and Enjoyment. Studies have begun to assess t... Read More about A longitudinal assessment of the responsiveness of the ICECAP-A in a randomised controlled trial of a knee pain intervention.

OP0105 Improving the Effectiveness of Exercise Therapy for Older Adults with Knee Osteoarthritis: A Pragmatic Randomised Controlled Trial (The Beep Trial) (2015)
Journal Article
Foster, N., Nicholls, E., Holden, M., Healey, E., Kigozi, J., Jowett, S., …Hay, E. (2015). OP0105 Improving the Effectiveness of Exercise Therapy for Older Adults with Knee Osteoarthritis: A Pragmatic Randomised Controlled Trial (The Beep Trial). Annals of the Rheumatic Diseases, 74(Suppl 2), 108.2-108. https://doi.org/10.1136/annrheumdis-2015-eular.1454

Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial (2015)
Journal Article
Healey, E. L., Jinks, C., Tan, V. A., Chew-Graham, C. A., Lawton, S. A., Nicholls, E., …Mallen, C. D. (2015). Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial. Journal of Comorbidity, 5(1), 135 -149. https://doi.org/10.15256/joc.2015.5.60

Background: Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused o... Read More about Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial.

Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial. (2015)
Journal Article
Dziedzic, K., Nicholls, E., Hill, S., Hammond, A., Handy, J., Thomas, E., & Hay, E. (2015). Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial. Annals of the Rheumatic Diseases, 74(1), 108 - 118. https://doi.org/10.1136/annrheumdis-2013-203938

BACKGROUND: Osteoarthritis is the leading cause of disability in older adults. Evidence of effectiveness for self-management of hand osteoarthritis is lacking. METHODS: In this randomised, factorial trial, we evaluated the effectiveness of joint prot... Read More about Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial..

Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity? (2014)
Journal Article
Marshall, M., Nicholls, E., Kwok, W., Peat, G., Kloppenburg, M., Van Der Windt, D., …Dziedzic, K. (2014). Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?. Annals of the Rheumatic Diseases, 74(1), 136 - 141. https://doi.org/10.1136/annrheumdis-2013-203948

OBJECTIVES: To determine whether erosive osteoarthritis shares the same pattern of joint involvement and risk profile as increasing grades of non-erosive hand osteoarthritis. METHODS: Participants were from two population-based cohorts, aged =50 year... Read More about Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?.

Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials (2014)
Journal Article
Oppong, R., Jowett, S., Nicholls, E., Whitehurst, D., Hill, S., Hammond, A., …Dziedzic, K. (2015). Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials. Rheumatology, 54(5), 876 - 883. https://doi.org/10.1093/rheumatology/keu389

OBJECTIVES: Evidence regarding the cost-effectiveness of joint protection and hand exercises for the management of hand OA is not well established. The primary aim of this study is to assess the cost-effectiveness (cost-utility) of these management o... Read More about Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials.

Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative (2014)
Journal Article
Nicholls, E., Thomas, E., van der Windt, D., Croft, P., & Peat, G. (2014). Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative. Osteoarthritis and Cartilage, 22(12), 2041 - 2050. https://doi.org/10.1016/j.joca.2014.09.026

OBJECTIVE: The authors aimed to characterize distinct trajectories of knee pain in adults who had, or were at high risk of, knee osteoarthritis using data from two population-based cohorts. METHOD: Latent class growth analysis was applied to measures... Read More about Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative.

Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings. (2013)
Journal Article
Marshall, M., Jonsson, H., Helgadottir, G. P., Nicholls, E., Van Der Windt, D., Myers, H., & Dziedzic, K. (2014). Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings. Arthritis Care & Research, 66(6), 828 - 836. https://doi.org/10.1002/acr.22225

OBJECTIVE: To investigate the reliability and construct validity of an atlas for grading hand osteoarthritis (OA) on photographs in a separate younger community-dwelling population than the development cohort. METHODS: Participants were community-dwe... Read More about Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings..

Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies. (2013)
Journal Article
Kwok, W., Kloppenburg, M., Marshall, M., Nicholls, E., Rosendaal, F. R., Van Der Windt, D. A., & Peat, G. (2013). Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies. Rheumatology, 52(12), 2260 - 2267. https://doi.org/10.1093/rheumatology/ket267

OBJECTIVE: To investigate in the general population the clinical impact of erosive OA in interphalangeal joints (IPJs) compared with symptomatic radiographic hand OA and inflammatory arthritis. METHODS: Standardized assessments with hand radiographs... Read More about Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies..

COST-EFFECTIVENESS OF JOINT PROTECTION AND HAND EXERCISE FOR HAND OSTEOARTHRITIS (2013)
Journal Article
Oppong, R., Jowett, S., Nicholls, E., Whitehurst, D., Hill, S., Hammond, A., …Dziedzic, K. (2013). COST-EFFECTIVENESS OF JOINT PROTECTION AND HAND EXERCISE FOR HAND OSTEOARTHRITIS. Rheumatology, 52(S1),

Background: European guidelines have proposed that joint protection and hand exercise should be used in the management of hand OA. However, the evidence regarding the cost-effectiveness of these interventions has not been well established. A 2x2 fact... Read More about COST-EFFECTIVENESS OF JOINT PROTECTION AND HAND EXERCISE FOR HAND OSTEOARTHRITIS.

ASSESSING HAND OSTEOARTHRITIS USING DIGITAL PHOTOGRAPHS IN A COMMUNITY-DWELLING POPULATION: RELIABILITY AND ASSOCIATIONS WITH RADIOGRAPHIC AND CLINICAL FEATURES (2013)
Journal Article
Marshall, M., Jonsson, H., Helgadottir, G. P., Nicholls, E., van der Windt, D., Myers, H., & Dziedzic, K. (2013). ASSESSING HAND OSTEOARTHRITIS USING DIGITAL PHOTOGRAPHS IN A COMMUNITY-DWELLING POPULATION: RELIABILITY AND ASSOCIATIONS WITH RADIOGRAPHIC AND CLINICAL FEATURES. Osteoarthritis and Cartilage, 21, S135-S135. https://doi.org/10.1016/j.joca.2013.02.286

Purpose: An atlas for grading hand osteoarthritis (OA) on photographs has been shown to be reliable and associated with clinical examination and radiographic features in a population of older adults (aged ≥69 years) from the AGES-Reykjavik study. The... Read More about ASSESSING HAND OSTEOARTHRITIS USING DIGITAL PHOTOGRAPHS IN A COMMUNITY-DWELLING POPULATION: RELIABILITY AND ASSOCIATIONS WITH RADIOGRAPHIC AND CLINICAL FEATURES.

Factors Associated with the Severity and Progression of Self-Reported Hand Pain and Functional Difficulty in Community-Dwelling Older Adults: A Systematic Review: Factors Associated with Hand Pain and Function (2012)
Journal Article
Nicholls, E. E., Windt, D. A. W. M., Jordan, J. L., Dziedzic, K. S., & Thomas, E. (2012). Factors Associated with the Severity and Progression of Self-Reported Hand Pain and Functional Difficulty in Community-Dwelling Older Adults: A Systematic Review: Factors Associated with Hand Pain and Function. Musculoskeletal Care, 10(1), 51-62. https://doi.org/10.1002/msc.1007

Background Hand problems are common in older adults and cause significant pain and disruption to everyday living. The aim of this systematic review was to summarize evidence on the factors associated with the severity and progression of self-reporte... Read More about Factors Associated with the Severity and Progression of Self-Reported Hand Pain and Functional Difficulty in Community-Dwelling Older Adults: A Systematic Review: Factors Associated with Hand Pain and Function.

Measures of Social Function and Participation in Musculoskeletal Populations Impact on Participation and Autonomy ( IPA), Keele Assessment of Participation (KAP), Participation Measure for Post-Acute Care (PM-PAC), Participation Objective, Participation Subjective (POPS), Rating of Perceived Participation (ROPP), and The Participation Scale (2011)
Journal Article
Wilkie, R., Jordan, J. L., Muller, S., Nicholls, E., Healey, E. L., & Van der Windt, D. A. (2011). Measures of Social Function and Participation in Musculoskeletal Populations Impact on Participation and Autonomy ( IPA), Keele Assessment of Participation (KAP), Participation Measure for Post-Acute Care (PM-PAC), Participation Objective, Participation Subjective (POPS), Rating of Perceived Participation (ROPP), and The Participation Scale. Arthritis Care and Research, 63(S11), S325-S336. https://doi.org/10.1002/acr.20641

Self-reported pain interference and symptoms of anxiety and depression in community-dwelling older adults: Can a temporal relationship be determined? (2010)
Journal Article
Arola, H., Nicholls, E., Mallen, C., & Thomas, E. (2010). Self-reported pain interference and symptoms of anxiety and depression in community-dwelling older adults: Can a temporal relationship be determined?. European Journal of Pain, 14(9), 966-971. https://doi.org/10.1016/j.ejpain.2010.02.012

Pain and symptoms of depression and anxiety have been observed to co-exist in the community-dwelling elderly. While depression and pain have been suggested to be predictive of one another temporally, the longitudinal associations between anxiety and... Read More about Self-reported pain interference and symptoms of anxiety and depression in community-dwelling older adults: Can a temporal relationship be determined?.

Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population. (2010)
Journal Article
Marshall, M., Myers, H., Dziedzic, K., Nicholls, E., & Van Der Windt, D. (2010). Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population. Rheumatology, 50(4), 735 - 739. https://doi.org/10.1093/rheumatology/keq371

OBJECTIVES: The aim of this study was to investigate: (i) the frequency and patterns of radiographic OA (ROA) in the thumb joints; and (ii) associations between thumb ROA and the clinical characteristics of thumb OA in older adults with hand pain or... Read More about Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population..

Measurement of change in function and disability in osteoarthritis: current approaches and future challenges (2009)
Journal Article
Jordan, K. P., Wilkie, R., Muller, S., Myers, H., & Nicholls, E. (2009). Measurement of change in function and disability in osteoarthritis: current approaches and future challenges. Current Opinion in Rheumatology, 21(5), 525-530. https://doi.org/10.1097/BOR.0b013e32832e45fc

Purpose of review This review assessed current approaches to using objective and self-report measures to determine change in function and disability in osteoarthritis and identified key future challenges. Recent findings New approaches to meas... Read More about Measurement of change in function and disability in osteoarthritis: current approaches and future challenges.

269 DEFINING 18-MONTH OUTCOME IN CLINICAL SUB-GROUPS OF HAND OSTEOARTHRITIS IN OLDER ADULTS: THE CLINICAL ASSESSMENT STUDY OF THE HAND (CAS-HA) (2008)
Journal Article
Dziedzic, K., Nicholls, E., Myers, H., Peat, G., Thomas, E., Marshall, M., & van der Windt, D. (2008). 269 DEFINING 18-MONTH OUTCOME IN CLINICAL SUB-GROUPS OF HAND OSTEOARTHRITIS IN OLDER ADULTS: THE CLINICAL ASSESSMENT STUDY OF THE HAND (CAS-HA). Osteoarthritis and Cartilage, 16(S4), S121-S122. https://doi.org/10.1016/s1063-4584%2808%2960313-1

The Clinical Assessment Study of the Hand (CAS-HA): a prospective study of musculoskeletal hand problems in the general population (2007)
Journal Article
Myers, H., Nicholls, E., Handy, J., Peat, G., Thomas, E., Duncan, R., …Dziedzic, K. (2007). The Clinical Assessment Study of the Hand (CAS-HA): a prospective study of musculoskeletal hand problems in the general population. BMC Musculoskeletal Disorders, 8, Article 85. https://doi.org/10.1186/1471-2474-8-85

Pain in the hand affects an estimated 12-21% of the population, and at older ages the hand is one of the most common sites of pain and osteoarthritis. The association between symptomatic hand osteoarthritis and disability in everyday life has not bee... Read More about The Clinical Assessment Study of the Hand (CAS-HA): a prospective study of musculoskeletal hand problems in the general population.

Radiographic presentation of osteoarthritis of the thumb (2007)
Presentation / Conference
Marshall, M., Dziedzic, K. . S., Nicholls, E. . E., Myers, H. . L., & Hay, E. . M. (2007, May). Radiographic presentation of osteoarthritis of the thumb. Paper presented at Annual Meeting of the British-Society-of-Rheumatology, Birmingham, ENGLAND