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Christian Mallen's Outputs (40)

JIGSAW-A PROCESS AND FEASIBILITY OF IMPLEMENTING GUIDELINE RECOMMENDATIONS FOR THE CARE OF OSTEOARTHRITIS IN WEST-AFRICA (2025)
Journal Article
Babatunde, O., Adetunji, O., Alonge, I., Owoyemi, T., Ayinmode, E., Ogunbanjo, A., White, S., Adebajo, A., Mallen, C., & Dziedzic, K. (in press). JIGSAW-A PROCESS AND FEASIBILITY OF IMPLEMENTING GUIDELINE RECOMMENDATIONS FOR THE CARE OF OSTEOARTHRITIS IN WEST-AFRICA. BMJ Global Health,

Objectives: To assess the feasibility of a guideline-informed model of care for osteoarthritis in primary healthcare and community pharmacy settings in West-African context.

Methods: 4-phase mixed-methods programme of research undertaken in south-... Read More about JIGSAW-A PROCESS AND FEASIBILITY OF IMPLEMENTING GUIDELINE RECOMMENDATIONS FOR THE CARE OF OSTEOARTHRITIS IN WEST-AFRICA.

Clinical and cost-effectiveness of communication skills e-learning for primary care practitioners on patients' musculoskeletal pain and enablement: the Talking in Primary care (TIP) cluster-randomised controlled trial (2025)
Preprint / Working Paper
Bishop, F. L., Becque, T., Garfield, K., Cross, N., Dewar-Haggart, R., Teasdale, E., Herbert, A., Robinson, M. E., Ridd, M. J., Mallen, C., Clarson, L., Bostock, J., Stuart, B., Morrison, L., Pollet, S., Vennik, J., Atherton, H., Howick, J., Leydon, G. M., Nuttall, J., …Everitt, H. A. (2025). Clinical and cost-effectiveness of communication skills e-learning for primary care practitioners on patients' musculoskeletal pain and enablement: the Talking in Primary care (TIP) cluster-randomised controlled trial

Objectives To determine the effectiveness and cost-effectiveness of a brief communication skills e-learning package on empathy and optimism for practitioners consulting with adult primary care patients presenting with musculoskeletal (MSK) pain.

D... Read More about Clinical and cost-effectiveness of communication skills e-learning for primary care practitioners on patients' musculoskeletal pain and enablement: the Talking in Primary care (TIP) cluster-randomised controlled trial.

Proactive clinical review of patients taking opioid medicines long term for persistent pain led by clinical pharmacists in primary care teams (PROMPPT): a non-randomised mixed-methods feasibility study (2025)
Journal Article
Ashworth, J., Cornwall, N., Harrisson, S., Woodcock, C., Nicholls, E., Lancaster, G., Wathall, S., Laing, L., Helliwell, T., Jowett, S., Kigozi, J., Mallen, C., Avery, A., Knaggs, R., Pincus, T., White, S., & Jinks, C. (in press). Proactive clinical review of patients taking opioid medicines long term for persistent pain led by clinical pharmacists in primary care teams (PROMPPT): a non-randomised mixed-methods feasibility study. Pilot and Feasibility Studies, https://doi.org/10.1186/s40814-025-01636-2

Background:
Given the poor long-term effectiveness of opioids for persistent non-cancer pain, and their potential for harm, evidence–based interventions to address opioid overprescribing for persistent pain are needed. This study aimed to explore th... Read More about Proactive clinical review of patients taking opioid medicines long term for persistent pain led by clinical pharmacists in primary care teams (PROMPPT): a non-randomised mixed-methods feasibility study.

Feasibility trial of a new digital training package to enhance primary care practitioners’ communication of clinical empathy and realistic optimism (2024)
Preprint / Working Paper
L Bishop, F., Howick, J., Vennik, J., Bostock, J., Little, P., Mallen, C., Morrison, L., Steele, M., Stuart, B., Hughes, S., Smith, K., Ratnapalan, M., Lyness, E., Dambha-Miller, H., Tiwari, R., Lockyer-Stevens, C., & Everitt, H. Feasibility trial of a new digital training package to enhance primary care practitioners’ communication of clinical empathy and realistic optimism

Interventions to promote colorectal cancer screening among people with a family history of colorectal cancer: A scoping review. (2024)
Journal Article
Firzara, A. M. T., Beh, H. C., Selvaraj, C. S., Mallen, C., Ng, C. J., & Lee, Y. K. (in press). Interventions to promote colorectal cancer screening among people with a family history of colorectal cancer: A scoping review. Preventive Medicine, 189(December 2024), 1-18. https://doi.org/10.1016/j.ypmed.2024.108137

The global incidence of colorectal cancer (CRC) is rising, with people having a family history of CRC (PFH-CRC) facing double the risk compared to the average-risk population. Despite this, CRC screening uptake among PFH-CRC remains low. There is a l... Read More about Interventions to promote colorectal cancer screening among people with a family history of colorectal cancer: A scoping review..

2235 National Trends in motor neurone disease-associated mortality from 1999–2020 (2024)
Presentation / Conference Contribution
Imantalab, D., Sokhal, B., Menon, S., Kara, S., Muller, S., & Mallen, C. 2235 National Trends in motor neurone disease-associated mortality from 1999–2020. Presented at British Geriatrics Society Spring 2024 Meeting (22 -24 May 2024), Vox, Birmingham, UK & Online

Introduction Motor Neurone Disease (MND) is a neurodegenerative condition affecting the spinal cord and brainstem, commonly associated with a reduced life expectancy. This study describes demographic trends in MND-associated mortality in the United S... Read More about 2235 National Trends in motor neurone disease-associated mortality from 1999–2020.

2234 Temporal trends in Parkinson’s disease-related mortality from 1999–2020: a Nationwide cohort study (2024)
Presentation / Conference Contribution
Sokhal, B., Menon, S., Shepherd, T., Muller, S., Arora, A., & Mallen, C. 2234 Temporal trends in Parkinson’s disease-related mortality from 1999–2020: a Nationwide cohort study. Presented at British Geriatrics Society Spring 2024 Meeting (22-24 May 2024), The Vox, Birminham, UK

Introduction Parkinson’s disease (PD) is the most common neurodegenerative movement disorder and is associated with significant disability. The prevalence of PD is increasing and the literature demonstrates potential sex and race disparities in patie... Read More about 2234 Temporal trends in Parkinson’s disease-related mortality from 1999–2020: a Nationwide cohort study.

2236 Emergency department attendance stratified by cause and frailty status: a national cohort study of over 155 million patients (2024)
Presentation / Conference Contribution
Sokhal, B., Matetić, A., Protheroe, J., Helliwell, T., Myint, P., Paul, T., Mallen, C., & Mamas, M. 2236 Emergency department attendance stratified by cause and frailty status: a national cohort study of over 155 million patients. Presented at British Geriatrics Society Spring 2024 Meeting (22 -24 May 2024), Vox, Birmingham, UK & Online

Introduction Data are limited on whether the causes of Emergency Department (ED) attendance and clinical outcomes vary by frailty status. Methods Using data from the Nationwide Emergency Department Sample, all ED attendances from 2016 to 2018 were st... Read More about 2236 Emergency department attendance stratified by cause and frailty status: a national cohort study of over 155 million patients.

Effectiveness of pneumococcal vaccination in adults with common immune-mediated inflammatory diseases in the UK: a case-control study. (2024)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Nguyen Van-Tam, J. S., & Abhishek, A. (2024). Effectiveness of pneumococcal vaccination in adults with common immune-mediated inflammatory diseases in the UK: a case-control study. The Lancet Rheumatology, 6(9), e615-e624. https://doi.org/10.1016/S2665-9913%2824%2900128-0

People with immune-mediated inflammatory disease are at increased risk of pneumococcal pneumonia. The effectiveness of pneumococcal vaccination in people with immune-mediated inflammatory diseases has not been evaluated. We investigated the effective... Read More about Effectiveness of pneumococcal vaccination in adults with common immune-mediated inflammatory diseases in the UK: a case-control study..

Hearing the patient voice for persistent pain intervention development: Recommendations for using a bespoke online discussion forum for qualitative data collection (2024)
Journal Article
Woodcock, C., Cornwall, N., Harrisson, S., Jinks, C., Buttery, A., Ashworth, J., Mallen, C. D., & Dikomitis, L. (2024). Hearing the patient voice for persistent pain intervention development: Recommendations for using a bespoke online discussion forum for qualitative data collection. British Journal of Pain, https://doi.org/10.1177/204946372412540

Introduction Understanding patients’ experiences is important when developing interventions for people living with persistent pain. Interviews and focus groups are frequently used to capture beliefs, views, and perspectives. These methods often requi... Read More about Hearing the patient voice for persistent pain intervention development: Recommendations for using a bespoke online discussion forum for qualitative data collection.

Relationship between research activity and the performance of English general practices: cross-sectional and longitudinal analyses (2024)
Journal Article
Gibson, J., Kontopantelis, E., Sutton, M., Boaz, A., Little, P., Mallen, C. D., McManus, R., Park, S., Usher-Smith, J., & Bower, P. (in press). Relationship between research activity and the performance of English general practices: cross-sectional and longitudinal analyses. British Journal of General Practice (BJGP), BJGP.2024.0111. https://doi.org/10.3399/BJGP.2024.0111

Research activity usually improves outcomes by being translated into practice. However, there is developing evidence that research activity itself may improve the overall performance of health care organisations. However, evidence that these relation... Read More about Relationship between research activity and the performance of English general practices: cross-sectional and longitudinal analyses.

Exploring practice and perspectives on shared decision-making about osteoporosis medicines in Fracture Liaison Services: the iFraP development qualitative study (2024)
Journal Article
Bullock, L., Manning, F., Hawarden, A., Fleming, J., Leyland, S., Clark, E. M., Thomas, S., Gidlow, C., Iglesias-Urrutia, C. P., Protheroe, J., Lefroy, J., Ryan, S., O’Neill, T. W., Mallen, C., Jinks, C., & Paskins, Z. (2024). Exploring practice and perspectives on shared decision-making about osteoporosis medicines in Fracture Liaison Services: the iFraP development qualitative study. Archives of Osteoporosis, 19(1), Article 50. https://doi.org/10.1007/s11657-024-01410-6

Summary
Interviews and focus groups with patients, FLS clinicians, and GPs identified challenges relating to clinical and shared decision-making about bone health and osteoporosis medicines. Findings will inform the development of the multicomponent... Read More about Exploring practice and perspectives on shared decision-making about osteoporosis medicines in Fracture Liaison Services: the iFraP development qualitative study.

Uptake, safety and effectiveness of inactivated influenza vaccine in inflammatory bowel disease: a UK-wide study (2024)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Nguyen Van-Tam, J. S., & Abhishek, A. (2024). Uptake, safety and effectiveness of inactivated influenza vaccine in inflammatory bowel disease: a UK-wide study. BMJ Open Gastroenterology, 11(1), Article e001370. https://doi.org/10.1136/bmjgast-2024-001370

Objective: To investigate (1) the UK-wide inactivated influenza vaccine (IIV) uptake in adults with inflammatory bowel disease (IBD), (2) the association between vaccination against influenza and IBD flare and (3) the effectiveness of IIV in preventi... Read More about Uptake, safety and effectiveness of inactivated influenza vaccine in inflammatory bowel disease: a UK-wide study.

2023 EULAR classification criteria for hand osteoarthritis. (2024)
Journal Article
Haugen, I. K., Felson, D. T., Abhishek, A., Berenbaum, F., Bierma-Zeinstra, S., Dziedzic, K. S., Edwards, J. J., Englund, M., Hermann-Eriksen, M., Herrero-Beaumont, G., Hill, C., Ishimori, M. L., Jonsson, H., Karjalainen, T., Leung, Y. Y., Maheu, E., Mallen, C. D., Marshall, M., Moe, R. H., Ramonda, R., …Kloppenburg, M. (2024). 2023 EULAR classification criteria for hand osteoarthritis. Annals of the Rheumatic Diseases, https://doi.org/10.1136/ard-2023-225073

The objective of this study is to develop classification criteria for overall hand osteoarthritis (OA), interphalangeal OA and thumb base OA based on self-reported data and radiographic features. The classification criteria sets were developed in thr... Read More about 2023 EULAR classification criteria for hand osteoarthritis..

P021 Uptake, safety, and effectiveness of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide study using data from the Clinical Practice Research Datalink (2024)
Presentation / Conference
Nakafero, G., Grainge, M. J., Mallen, C. D., Card, T., Nguyen Van-Tam, J. S., & Abhishek, A. (2024, April). P021 Uptake, safety, and effectiveness of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide study using data from the Clinical Practice Research Datalink. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims The safety and effectiveness of pneumococcal vaccine in people with immune mediated inflammatory diseases (IMIDs) is not known, which may contribute to suboptimal uptake. We investigated UK wide pneumococcal vaccine uptake in adults w... Read More about P021 Uptake, safety, and effectiveness of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide study using data from the Clinical Practice Research Datalink.

P080 Supporting shared decision-making about osteoporosis medicines: Combining multiple methods to develop the prototype iFraP intervention (2024)
Presentation / Conference Contribution
Bullock, L., Fleming, J., Clark, E. M., Leyland, S., Thomas, S., Gidlow, C., O'Neill, T. W., Iglesias-Urrutia, C. P., Hawarden, A., Manning, F., Protheroe, J., Lefroy, J., Ryan, S., Horne, R., Mallen, C. D., Jinks, C., & Paskins, Z. (2024, April). P080 Supporting shared decision-making about osteoporosis medicines: Combining multiple methods to develop the prototype iFraP intervention. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Shared decision-making (SDM) is a joint process in which a person and healthcare professional work together to reach decisions about care. The iFraP (Improving uptake of Fracture Prevention drug treatments) intervention comprises comp... Read More about P080 Supporting shared decision-making about osteoporosis medicines: Combining multiple methods to develop the prototype iFraP intervention.

P185 Anatomical patterns of pain in primary care patients with polymyalgia rheumatica compared to the general population (2024)
Presentation / Conference
Hammad, N., Partington, R., Hider, S., Butt, H., Helliwell, T., Mallen, C., & Muller, S. (2024, April). P185 Anatomical patterns of pain in primary care patients with polymyalgia rheumatica compared to the general population. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Polymyalgia rheumatica (PMR) is common in older adults, causing severe pain and stiffness, particularly in the shoulder and hip girdles. A tapered course of glucocorticoids is recommended, but not always straightforward, with frequent... Read More about P185 Anatomical patterns of pain in primary care patients with polymyalgia rheumatica compared to the general population.