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Christian Mallen's Outputs (17)

P187 Fatigue in people with polymyalgia rheumatica: a key unmet need? (2024)
Presentation / Conference
Muller, S., Belcher, J., Hider, S., Helliwell, T., & Mallen, C. D. (2024, April). P187 Fatigue in people with polymyalgia rheumatica: a key unmet need?. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Polymyalgia rheumatica (PMR) is common in older adults, causing severe pain and stiffness, particularly in the shoulder and hip girdles. Glucocorticoids treatment generally focusses on reducing pain and stiffness, but there are other... Read More about P187 Fatigue in people with polymyalgia rheumatica: a key unmet need?.

P185 Anatomical patterns of pain in primary care patients with polymyalgia rheumatica compared to the general population (2024)
Presentation / Conference
Hammad, N., Partington, R., Hider, S., Butt, H., Helliwell, T., Mallen, C., & Muller, S. (2024, April). P185 Anatomical patterns of pain in primary care patients with polymyalgia rheumatica compared to the general population. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Polymyalgia rheumatica (PMR) is common in older adults, causing severe pain and stiffness, particularly in the shoulder and hip girdles. A tapered course of glucocorticoids is recommended, but not always straightforward, with frequent... Read More about P185 Anatomical patterns of pain in primary care patients with polymyalgia rheumatica compared to the general population.

P021 Uptake, safety, and effectiveness of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide study using data from the Clinical Practice Research Datalink (2024)
Presentation / Conference
Nakafero, G., Grainge, M. J., Mallen, C. D., Card, T., Nguyen Van-Tam, J. S., & Abhishek, A. (2024, April). P021 Uptake, safety, and effectiveness of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide study using data from the Clinical Practice Research Datalink. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims The safety and effectiveness of pneumococcal vaccine in people with immune mediated inflammatory diseases (IMIDs) is not known, which may contribute to suboptimal uptake. We investigated UK wide pneumococcal vaccine uptake in adults w... Read More about P021 Uptake, safety, and effectiveness of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide study using data from the Clinical Practice Research Datalink.

P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study (2023)
Presentation / Conference
Padmanabhan, N., Muller, S., Bailey, J., Helliwell, T., Mackie, S. L., Mallen, C. D., & Roddy, E. (2023, April). P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Giant cell arteritis (GCA) is considered a medical emergency, and relapses are common, affecting around 50% of patients. Many of the early symptoms of GCA are non-specific and highly prevalent in older people, making the diagnosis challenging.

The... Read More about P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study.

P115 Healthcare professionals' perspectives on integrating predictive and emerging preventive approaches in rheumatoid arthritis care: A qualitative investigation (2023)
Presentation / Conference
Simons, G., Wells, I., Kanacherril, J. P., Mallen, C. D., Raza, K., & Falahee, M. (2023, April). P115 Healthcare professionals' perspectives on integrating predictive and emerging preventive approaches in rheumatoid arthritis care: A qualitative investigation. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Metformin use and the risk of total knee replacement among diabetic patients in primary care (2021)
Presentation / Conference
Sit, R., Lai, F., Yip, B., Hunter, D., Rabago, D., Mallen, C., & Wong, S. (2021, April). Metformin use and the risk of total knee replacement among diabetic patients in primary care. Presented at Virtual 2021 OARSI World Congress on Osteoarthritis, Virtual

Purpose: Metformin, apart from its glucose lowering and weight reduction effects, has recently been shown to modulate meta-inflammation, an important pathogenesis in knee osteoarthritis (OA). We aim to study the association between regular metformin... Read More about Metformin use and the risk of total knee replacement among diabetic patients in primary care.

P148 Gastrointestinal symptoms and proton pump inhibitor use in patients with polymyalgia rheumatica: results from the PMR Cohort study (2020)
Presentation / Conference
Feddah, H., Muller, S., Hider, S., Hay, C., & Mallen, C. (2020, April). P148 Gastrointestinal symptoms and proton pump inhibitor use in patients with polymyalgia rheumatica: results from the PMR Cohort study. Poster presented at British Society for Rheumatology Annual Conference 2020, - Cancelled -

Background
Polymyalgia Rheumatica (PMR) is a common disorder of older adults, characterised by pain and stiffness in the shoulders and hips. PMR is one of the commonest indications for long-term glucocorticoid use. Because of the well-recognised sid... Read More about P148 Gastrointestinal symptoms and proton pump inhibitor use in patients with polymyalgia rheumatica: results from the PMR Cohort study.

The relationship between obesity and outcomes in patients with polymyalgia rheumatica (2020)
Presentation / Conference
Scott, I. C., Bajpai, R., Mallen, C., Muller, S., Helliwell, T., & Hider, S. (2020, April). The relationship between obesity and outcomes in patients with polymyalgia rheumatica. Presented at British Society for Rheumatology Annual Conference 2020, Scottish Event Campus (SEC), Scotland, UK

Background
Obesity predisposes to a pro-inflammatory state. Studies have reported worse clinical outcomes in patients with inflammatory arthritis who are obese. The relationship between obesity and outcomes in patients with polymyalgia rheumatica (P... Read More about The relationship between obesity and outcomes in patients with polymyalgia rheumatica.

Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study (2018)
Presentation / Conference
Crowley, L., Abdul Sultan, A., Roddy, E., Mallen, C., Protheroe, J., & Clarson, L. (2018, October). Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study. Poster presented at 2018 ACR/ARHP Annual Meeting

Background/Purpose: Evidence is conflicting concerning dementia risk in gout patients, with hyperuricaemia proposed to exert a neuroprotective effect. Serum urate (sUA) targets guiding urate-lowering therapies (ULT) are poorly evidenced-based and th... Read More about Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study.

Exploring discrepancies between long-term condition review consultation audio-recordings and computer template data (the ENHANCE pilot trial) (2017)
Presentation / Conference
Liddle, J., Lawton, S. A., Chew-Graham, C. A., Healey, E. L., Mallen, C. D., & Jinks, C. (2017, May). Exploring discrepancies between long-term condition review consultation audio-recordings and computer template data (the ENHANCE pilot trial). Presented at 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials, Liverpool, UK

SO LOOKING AT THIS, YOU LOOK LIKE YOU'VE GOT SOME ISSUES GOING ON WITH YOUR JOINTS: EXPLORING CASE-FINDING IN LONG-TERM CONDITION REVIEW CONSULTATIONS-THE ENHANCE PILOT TRIAL (2017)
Presentation / Conference
Liddle, J., Chew-Graham, C. A., Mallen, C. D., Healey, E. L., Jinks, C., & Dikomitis, L. (2017, April). SO LOOKING AT THIS, YOU LOOK LIKE YOU'VE GOT SOME ISSUES GOING ON WITH YOUR JOINTS: EXPLORING CASE-FINDING IN LONG-TERM CONDITION REVIEW CONSULTATIONS-THE ENHANCE PILOT TRIAL. Poster presented at Rheumatology 2017, Birmingham ICC, England, UK

O21 The Impact of Symptom Recognition on Help-Seeking: A Comparison Between Rheumatoid Arthritis, Bowel Cancer and Angina (2016)
Presentation / Conference
Simons, G., Belcher, J., Kumar, K., Falahee, M., Mallen, C. D., Stack, R., & Raza, K. (2016, April). O21 The Impact of Symptom Recognition on Help-Seeking: A Comparison Between Rheumatoid Arthritis, Bowel Cancer and Angina. Presented at Rheumatology 2016, SECC Glasgow, UK

Background: RA requires early treatment to reduce the risk of joint damage and disability. However, due to delays at various points in the patient’s journey following symptom onset, this therapeutic window is often missed. Patients themselves are an... Read More about O21 The Impact of Symptom Recognition on Help-Seeking: A Comparison Between Rheumatoid Arthritis, Bowel Cancer and Angina.

Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD). (2014)
Presentation / Conference
Muller, S., Paskins, Z., Hider, S., Mallen, C., Roddy, E., & Bucknall, M. (2014, November). Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD). Poster presented at 2014 ACR/ARHP Annual Meeting, Boston, MA, usa

Background/Purpose: Acute pseudogout is the most dramatic clinical manifestation of calcium pyrophosphate crystal deposition (CPPD). CPPD is most commonly sporadic and age-related but can rarely occur secondary to metabolic diseases or a familial tra... Read More about Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD)..

SAT0503 Eligibility for Urate-Lowering Treatment around the Time of Diagnosis in Gout Patients: A Nationwide Population Study (2014)
Presentation / Conference
Kuo, C.-F., Grainge, M., Mallen, C., Zhang, W., & Doherty, M. (2014, June). SAT0503 Eligibility for Urate-Lowering Treatment around the Time of Diagnosis in Gout Patients: A Nationwide Population Study. Presented at EULAR 2014, Paris, France

Background
Current guidelines and recommendations [1-3] recommend urate-lowering treatment (ULT) only for patients with more severe disease or with other concomitant conditions that merit earlier ULT. However, whe... Read More about SAT0503 Eligibility for Urate-Lowering Treatment around the Time of Diagnosis in Gout Patients: A Nationwide Population Study.

O30. The Risk of a Subsequent Cancer Diagnosis after PMR: A Primary Care Database Study (2013)
Presentation / Conference
Muller, S., Mallen, C. D., Belcher, J., Helliwell, T., & Hider, S. L. (2013, April). O30. The Risk of a Subsequent Cancer Diagnosis after PMR: A Primary Care Database Study. Presented at Annual Meeting of the British Society for Rheumatology and British Health Professionals in Rheumatology, Birmingham, ENGLAND

Background: PMR is the commonest inflammatory rheumatological disorder managed in primary care. Other inflammatory conditions such as RA and psoriasis have been associated with an increased incidence of cancer, specifically haematological malignancie... Read More about O30. The Risk of a Subsequent Cancer Diagnosis after PMR: A Primary Care Database Study.

042 Challenges Faced in Primary Care During the Early Stages of Rheumatoid Arthritis: A Cross-Sectional Survey of General Practitioners
Presentation / Conference
Mangat, N. S., Raza, K., Clarkson, K., Stack, R., Mallen, C., Belcher, J., & Hider, S. 042 Challenges Faced in Primary Care During the Early Stages of Rheumatoid Arthritis: A Cross-Sectional Survey of General Practitioners. Poster presented at Rheumatology 2016

Background: Early treatment can reduce morbidity and mortality in patients with RA. However, identifying early RA can be challenging, in part because many of its initial symptoms are non-specific. Delays in recognising RA and referral to secondary ca... Read More about 042 Challenges Faced in Primary Care During the Early Stages of Rheumatoid Arthritis: A Cross-Sectional Survey of General Practitioners.