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Anthony Curtis' Outputs (26)

Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents (2015)
Journal Article
Hoskins, C., & Curtis, A. D. Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents. Journal of Nanomedicine Research, 2(3), https://doi.org/10.15406/jnmr.2015.02.00028

Many drug molecules have low solubility in aqueous media and, hence, poor bioavailability. The formation of a host-guest complex with some other compound which has a good solubility profile can facilitate solubilization of hydrophobic drugs. Complex... Read More about Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents.

Enhancement of the Cytotoxic Effect of Anticancer Agent by Cytochrome c Functionalised Hybrid Nanoparticles in Hepatocellular Cancer Cells (2014)
Journal Article
Malekigorji, M., Hoskins, C., Curtis, T., & Varbiro, G. Enhancement of the Cytotoxic Effect of Anticancer Agent by Cytochrome c Functionalised Hybrid Nanoparticles in Hepatocellular Cancer Cells. Journal of Nanomedicine Research, 1(2), https://doi.org/10.15406/jnmr.2014.01.00010

Treatment of hepatocellular cancer with chemotherapeutic agents has limited success in clinical practice and their efficient IC50 concentration would require extremely high doses of drug administration which could not be tolerated due to systemic sid... Read More about Enhancement of the Cytotoxic Effect of Anticancer Agent by Cytochrome c Functionalised Hybrid Nanoparticles in Hepatocellular Cancer Cells.

The Use of Iron Oxide Nanoparticles for Pancreatic Cancer Therapy (2014)
Journal Article
Malekigorji, M., DM Curtis, A., & Hoskins, C. The Use of Iron Oxide Nanoparticles for Pancreatic Cancer Therapy. Journal of Nanomedicine Research, 1(1), https://doi.org/10.15406/jnmr.2014.01.00004

Over the last decade major advances have been made in the treatment of cancer such as breast and leukaemia. However, no satisfactory progress has been made in the effective treatment of pancreatic cancer. Treatment of this disease is hindered by resi... Read More about The Use of Iron Oxide Nanoparticles for Pancreatic Cancer Therapy.

Simulated Drug Discovery Process to Conduct a Synoptic Assessment of Pharmacy Students (2014)
Journal Article
Richardson, A., Curtis, A. D., Moss, G. P., Pearson, R. J., White, S., Rutten, F. J., Perumal, D., & Maddock, K. (2014). Simulated Drug Discovery Process to Conduct a Synoptic Assessment of Pharmacy Students. American journal of pharmaceutical education, 78(2), 41. https://doi.org/10.5688/ajpe78241

Objective. To implement and assess a task-based learning exercise that prompts pharmacy students to integrate their understanding of different disciplines.

Design. Master of pharmacy (MPharm degree) students were provided with simulated informatio... Read More about Simulated Drug Discovery Process to Conduct a Synoptic Assessment of Pharmacy Students.

Preclinical evaluation of statins as a treatment for ovarian cancer (2013)
Journal Article
Robinson, E., Nandi, M., Wilkinson, L. L., Arrowsmith, D. M., Curtis, A. D., & Richardson, A. (2013). Preclinical evaluation of statins as a treatment for ovarian cancer. Gynecologic Oncology, 129(2), 417-424. https://doi.org/10.1016/j.ygyno.2013.02.003

Objective
To evaluate the potential for statins to treat ovarian cancer.

Methods
The sensitivity of 7 ovarian cancer cell lines to either statins or statins combined with either carboplatin or paclitaxel was assessed using monolayer cultures. Se... Read More about Preclinical evaluation of statins as a treatment for ovarian cancer.