Outputs (3)

Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis. (2021)
Journal Article
Horsley, A. R., Belcher, J., Bayfield, K., Bianco, B., Cunningham, S., Fullwood, C., …Gilchrist, F. J. (2021). Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis. Thorax, 77(4), https://doi.org/10.1136/thoraxjnl-2021-216928

BACKGROUND: Lung clearance index (LCI) is a valuable research tool in cystic fibrosis (CF) but clinical application has been limited by technical challenges and uncertainty about how to interpret longitudinal change. In order to help inform clinical... Read More about Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis..

Mortality in Patients With Gout Treated With Allopurinol: A Systematic Review and Meta‐Analysis (2021)
Journal Article
Hay, C. A., Prior, J. A., Belcher, J., Mallen, C. D., & Roddy, E. (2021). Mortality in Patients With Gout Treated With Allopurinol: A Systematic Review and Meta‐Analysis. Arthritis Care & Research, 73(7), 1049-1054. https://doi.org/10.1002/acr.24205

ObjectiveUrate‐lowering therapy (predominantly allopurinol) is highly effective as a treatment for gout, but its wider long‐term effects remain unclear. This systematic review and meta‐analysis aimed to ascertain the association between mortality and... Read More about Mortality in Patients With Gout Treated With Allopurinol: A Systematic Review and Meta‐Analysis.

Non-invasive ventilation is associated with long-term improvements in lung function and gas exchange in cystic fibrosis adults with hypercapnic respiratory failure (2021)
Journal Article
Wadsworth, L., Belcher, J., & Bright-Thomas, R. (2021). Non-invasive ventilation is associated with long-term improvements in lung function and gas exchange in cystic fibrosis adults with hypercapnic respiratory failure. Journal of Cystic Fibrosis, 20(5), e40-e45. https://doi.org/10.1016/j.jcf.2021.05.011

Non-invasive ventilation (NIV) is an established treatment option for cystic fibrosis (CF) patients with type 2 respiratory failure but the benefits of this therapy remain unclear. This study examined the long-term outcomes and response to NIV in a l... Read More about Non-invasive ventilation is associated with long-term improvements in lung function and gas exchange in cystic fibrosis adults with hypercapnic respiratory failure.