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Outputs (566)

Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register. (2020)
Journal Article
Iskandar, I., Warren, R., Lunt, M., Mason, K., Evans, I., McElhone, K., …Ashcroft, D. (2020). Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register. JAMA Dermatology, 157(1), 66-73. https://doi.org/10.1001/jamadermatol.2020.4202

Importance: Treatments for psoriasis may be less effective in everyday practice than in clinical trials. Emulating a target trial using data from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) can provide t... Read More about Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register..

Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. (2020)
Journal Article
Mamas. (2020). Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. Resuscitation, 166 - 173. https://doi.org/10.1016/j.resuscitation.2020.10.005

AIMS: The aim of this study is to analyse the causes of cardiac arrests (CA) in the emergency departments (ED) in the United States and their clinical outcomes according to whether they had a primary or a secondary diagnosis of CA. METHODS: Data from... Read More about Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample..

Race and racism: are we too comfortable with comfort? (2020)
Journal Article
Silverwood. (2020). Race and racism: are we too comfortable with comfort?. British Journal of General Practice Open (BJGP Open), https://doi.org/10.3399/BJGPO.2020.0143

After the murder of George Floyd and the Black Lives Matter protests, there has been a renewed appetite to tackle racism in all aspects of life. Within medicine and especially primary care, many people seem unclear about the racial disparities in hea... Read More about Race and racism: are we too comfortable with comfort?.

Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. (2020)
Journal Article
(2020). Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. Health Technology Assessment, 1 - 252. https://doi.org/10.3310/hta24720

BACKGROUND: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. OBJECTIVES: To assess the performance of existing pre-eclampsia prediction models and... Read More about Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis..

The prognostic value of Tei index in acute myocardial infarction: a systematic review (2020)
Journal Article
(2020). The prognostic value of Tei index in acute myocardial infarction: a systematic review. Echo Research and Practice, 49 - 58. https://doi.org/10.1530/ERP-20-0017

Background: Echocardiographic evaluation of left ventricular ejection fraction (LVEF) is used in the risk stratification of patients with an acute myocardial infarction (AMI). However, the prognostic value of the Tei index, an alternative measure of... Read More about The prognostic value of Tei index in acute myocardial infarction: a systematic review.

Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry. (2020)
Journal Article
Lambie. (2020). Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry. Clinical Kidney Journal, 1003 - 1011. https://doi.org/10.1093/ckj/sfaa051

Background: There is limited information available on the use of assisted peritoneal dialysis (PD) over time and the impact of economic incentives on its utilization. The aim of this study was to describe the trends in assisted PD utilization and the... Read More about Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry..

Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial. (2020)
Journal Article
Chew-Graham. (2020). Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial. Journal of Psychopharmacology, 1342 - 1349. https://doi.org/10.1177/0269881120965939

BACKGROUND: There is a lack of evidence to guide treatment of comorbid depression and anxiety. Preliminary evidence suggests mirtazapine may be effective in treating patients with both depression and anxiety symptoms. METHODS: We undertook a secondar... Read More about Does anxiety moderate the effectiveness of mirtazapine in patients with treatment-resistant depression? A secondary analysis of the MIR trial..