Outputs (21)

Developing a Biomimetic 3D Neointimal Layer as a Prothrombotic Substrate for a Humanized In Vitro Model of Atherothrombosis (2024)
Journal Article
Echrish, J., Pasca, M.-I., Cabrera, D., Yang, Y., & Harper, A. G. S. (2024). Developing a Biomimetic 3D Neointimal Layer as a Prothrombotic Substrate for a Humanized In Vitro Model of Atherothrombosis. Biomimetics, 9(6), Article 372. https://doi.org/10.3390/biomimetics9060372

Acute cardiovascular events result from clots caused by the rupture and erosion of atherosclerotic plaques. This paper aimed to produce a functional biomimetic hydrogel of the neointimal layer of the atherosclerotic plaque that can support thrombogen... Read More about Developing a Biomimetic 3D Neointimal Layer as a Prothrombotic Substrate for a Humanized In Vitro Model of Atherothrombosis.

Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples (2024)
Journal Article
Sharifabad, M. E., Eizadi Sharifabad, M., Soucaille, R., Wang, X., Rotherham, M., Loughran, T., …Telling, N. (2024). Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples. ACS Nano, 18(7), 5297-5310. https://doi.org/10.1021/acsnano.3c08955

The study of exogenous and endogenous nanoscale magnetic material in biology is important for developing biomedical nanotechnology as well as for understanding fundamental biological processes such as iron metabolism and biomineralization. Here, we e... Read More about Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples.

Multiparametric Modulation of Magnetic Transduction for Biomolecular Sensing in Liquids (2024)
Journal Article
Sanz-de Diego, E., Aires, A., Palacios Alonso, P., Cabrera, D., Silvestri, N., Artés-Ibañez, E. J., …Teran, F. J. J. (2024). Multiparametric Modulation of Magnetic Transduction for Biomolecular Sensing in Liquids. Nanoscale, 16(8), 4082-4094. https://doi.org/10.1039/d3nr06489a

The recent COVID19 pandemic has remarkably boosted the research on in vitro diagnosis assays to detect biomarkers in biological fluids. Specificity and sensitivity are mandatory for diagnostic kits aiming to reach clinical stages. Whilst the modulati... Read More about Multiparametric Modulation of Magnetic Transduction for Biomolecular Sensing in Liquids.

Magnetic Coagulometry: Towards a New Nanotechnological Tool for ex vivo Monitoring Coagulation in Human Whole Blood (2023)
Journal Article
Santana-Otero, A., Harper, A., Telling, N. D., Ortega, D., & Cabrera, D. (in press). Magnetic Coagulometry: Towards a New Nanotechnological Tool for ex vivo Monitoring Coagulation in Human Whole Blood. Nanoscale, https://doi.org/10.1039/d3nr02593d

Blood clotting disorders consisting of unwanted blood clot formation or excessive bleeding are some of the main causes of death worldwide. However, there are significant limitations in the current methods used to clinically monitoring the dynamics of... Read More about Magnetic Coagulometry: Towards a New Nanotechnological Tool for ex vivo Monitoring Coagulation in Human Whole Blood.

Iron oxide nanoparticles as a new tool for treating cardiovascular diseases (2023)
Conference Proceeding
Cabrera, D., Ranjbar, J., Santana-Otero, A., Sharifabad, M. E., Ortega, D., Telling, N. D., & Harper, A. (2023). Iron oxide nanoparticles as a new tool for treating cardiovascular diseases. . https://doi.org/10.1109/intermagshortpapers58606.2023.10228198

Thrombotic events are a major cause of death and disability worldwide. Thrombolysis with the clot busting drug tissue plasminogen activator (tPA) or thromboprophylaxis using anticoagulants such as heparin are frontline treatments for thrombotic disea... Read More about Iron oxide nanoparticles as a new tool for treating cardiovascular diseases.

Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method (2023)
Journal Article
Wang, X., Cabrera, D., Yang, Y., & Telling, N. (in press). Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method. Frontiers in Nanotechnology, 5, Article 1214313. https://doi.org/10.3389/fnano.2023.1214313

Magnetic nanoparticles (MNPs) are promising as local heat generators for magnetic hyperthermia under AC magnetic fields. The heating efficacy of MNPs is determined by the AC hysteresis loop area, which in turn is affected by the dynamic magnetic prop... Read More about Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method.

Clot-Targeted Magnetic Hyperthermia Permeabilizes Blood Clots to Make Them More Susceptible to Thrombolysis (2022)
Journal Article
Cabrera, D., Sharifabad, M. E., Ranjbar, J. A., Telling, N. D., & Harper, A. G. (2022). Clot-Targeted Magnetic Hyperthermia Permeabilizes Blood Clots to Make Them More Susceptible to Thrombolysis. Journal of Thrombosis and Haemostasis, 20(11), https://doi.org/10.1111/jth.15846

BACKGROUND: Thrombolysis is a frontline treatment for stroke, which involves the application of tissue plasminogen activator (tPA) to trigger endogenous clot-degradation pathways.However, it is only effective within 4.5 hours of symptom onset due to... Read More about Clot-Targeted Magnetic Hyperthermia Permeabilizes Blood Clots to Make Them More Susceptible to Thrombolysis.

Superparamagnetic-blocked state transition under alternating magnetic fields: towards determining the magnetic anisotropy in magnetic suspensions (2022)
Journal Article
Cabrera, D., Yoshida, T., Rincón-Domínguez, T., Cuñado, J., Salas, G., Bollero, A., …Teran, F. J. (2022). Superparamagnetic-blocked state transition under alternating magnetic fields: towards determining the magnetic anisotropy in magnetic suspensions. Nanoscale, 14(24), 8789-8796. https://doi.org/10.1039/D2NR00808D

The potential of magnetic nanoparticles for acting as efficient catalysts, imaging tracers or heating mediators relays on their superparamagnetic behaviour under alternating magnetic fields. In spite of the relevance of this magnetic phenomenon, the... Read More about Superparamagnetic-blocked state transition under alternating magnetic fields: towards determining the magnetic anisotropy in magnetic suspensions.

Controlling human platelet activation with calcium-binding nanoparticles (2020)
Journal Article
Cabrera, D., Walker, K., Moise, S., Telling, N. D., & Harper, A. G. (2020). Controlling human platelet activation with calcium-binding nanoparticles. Nano Research, 13, Article 2697–2705. https://doi.org/10.1007/s12274-020-2912-8

We introduce a neural method that is able to fuse concepts from a knowledge base with the context information for the task of grouping of aspect terms. Rather than only using context information, we use the corresponding concepts of aspect terms as a... Read More about Controlling human platelet activation with calcium-binding nanoparticles.

Dynamical Magnetic Response of Iron Oxide Nanoparticles Inside Live Cells (2018)
Journal Article
Cabrera, D., Coene, A., Leliaert, J., Artés-Ibáñez, E. J., Dupré, L., Telling, N. D., & Teran, F. J. (2018). Dynamical Magnetic Response of Iron Oxide Nanoparticles Inside Live Cells. ACS nano, 12(3), 2741-2752. https://doi.org/10.1021/acsnano.7b08995

Magnetic nanoparticles exposed to alternating magnetic fields have shown a great potential acting as magnetic hyperthermia mediators for cancer treatment. However, a dramatic and unexplained reduction of the nanoparticle magnetic heating efficiency h... Read More about Dynamical Magnetic Response of Iron Oxide Nanoparticles Inside Live Cells.