Skip to main content

Research Repository

Advanced Search

Outputs (3)

Less is more: Investigating the influence of cellular nanoparticle load on transfection outcomes in neural cells (2019)
Journal Article
Chari, D. M., & Tickle, J. A. (2019). Less is more: Investigating the influence of cellular nanoparticle load on transfection outcomes in neural cells. Journal of Tissue Engineering and Regenerative Medicine, https://doi.org/10.1002/term.2909

Genetic engineering of cell transplant populations offers potential for delivery of neurotherapeutic factors to modify the regenerative microenvironment of the injured spinal cord. The use of magnetic nanoparticle (MNP) based vectors has reduced the... Read More about Less is more: Investigating the influence of cellular nanoparticle load on transfection outcomes in neural cells.

Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices (2019)
Journal Article
Adams, C., Delaney, A., Carwardine, D., Tickle, J., Granger, N., & Chari, D. (2019). Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices. Macromolecular Bioscience, 19, e1800389. https://doi.org/10.1002/mabi.201800389

A recent clinical trial proves that autologous olfactory mucosal cell (OMC) transplantation improves locomotion in dogs with naturally occurring spinal injuries comparable to human lesions. However, not all dogs respond to the treatment, likely due t... Read More about Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices.