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Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry (2017)
Journal Article
Mamas. (2017). Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.116.004695

Background
Aortic valve predilation with balloon aortic valvuloplasty (BAV) is recommended before transcatheter aortic valve implantation (TAVI), despite limited data around the requirement of this preprocedural step and the potential risks of embol... Read More about Pre-implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry.

Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom (2017)
Journal Article
Hulme, W., Sperrin, M., Kontopantelis, E., Ratib, K., Ludman, P., Sirker, A., …Mamas, M. (2017). Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom. Circulation: Cardiovascular Interventions, 10(2), 4279. https://doi.org/10.1161/CIRCINTERVENTIONS.116.004279

Background—
The radial artery is increasingly adopted as the primary access site for cardiac catheterization because of patient preference, lower bleeding rates, cost effectiveness, and reduced risk of mortality in high-risk patient groups. Concerns... Read More about Increased radial access is not associated with worse femoral outcomes for PCI in the United Kingdom.

Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database (2017)
Journal Article
Mamas. (2017). Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database. Cardiovascular Revascularization Medicine, 250-254. https://doi.org/10.1016/j.carrev.2017.02.005

Aims
Pre-procedural ventilation is a marker of high risk in PCI patients. Causes include out-of-hospital cardiac arrest (OHCA) and cardiogenic shock. OHCA occurs in approximately 60,000 patients in the UK per annum. No consensus exists regarding the... Read More about Variation in emergency percutaneous coronary intervention in ventilated patients in the UK: insights from a national database.

Impact of HIV on inpatient mortality and complications in stroke in Thailand; A National Database Study (2017)
Journal Article
Mamas. (2017). Impact of HIV on inpatient mortality and complications in stroke in Thailand; A National Database Study. Epidemiology and Infection, 1285-1291. https://doi.org/10.1017/S095026881600340X

The co-existence of stroke and HIV has increased in recent years, but the impact of HIV on post-stroke outcomes is poorly understood. We examined the impact of HIV on inpatient mortality, length of acute hospital stay and complications (pneumonia, re... Read More about Impact of HIV on inpatient mortality and complications in stroke in Thailand; A National Database Study.

Response to letter by Dziewierz et al. on “Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta- analysis” (2017)
Journal Article
Mamas. (2017). Response to letter by Dziewierz et al. on “Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta- analysis”. American Heart Journal, 107-119. https://doi.org/10.1016/j.ahj.2017.01.013

Letter to the editor.

Endothelial progenitor cells: exploring the pleiotropic effects of statins (2017)
Journal Article
Mamas. (2017). Endothelial progenitor cells: exploring the pleiotropic effects of statins. World Journal of Cardiology, 1-13. https://doi.org/10.4330/wjc.v9.i1.1

Statins have become a cornerstone of risk modification for ischaemic heart disease patients. A number of studies have shown that they are effective and safe. However studies have observed an early benefit in terms of a reduction in recurrent infarct... Read More about Endothelial progenitor cells: exploring the pleiotropic effects of statins.

One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study (2017)
Journal Article
Mamas. (2017). One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study. PloS one, https://doi.org/10.1371/journal.pone.0162072

Background
Predicting which individuals will have a decline in left ventricular (LV) function after pacemaker implantation remains an important challenge. We investigated whether LV global longitudinal strain (GLS), measured by 2D speckle tracking s... Read More about One-month global longitudinal strain identifies patients who will develop pacing-induced left ventricular dysfunction over time: the pacing and ventricular dysfunction (PAVD) study.

Radiotherapy-induced cardiac implantable electronic device disorders in cancer patients (2017)
Journal Article
Mamas. (2017). Radiotherapy-induced cardiac implantable electronic device disorders in cancer patients. American Journal of Cardiology, 284-289. https://doi.org/10.1016/j.amjcard.2016.09.036

Radiotherapy can affect the electronic components of a cardiac implantable electronic device (CIED) resulting in malfunction and/or damage. We sought to assess the incidence, predictors, and clinical impact of CIED dysfunction (CIED-D) after radiothe... Read More about Radiotherapy-induced cardiac implantable electronic device disorders in cancer patients.

Clinical Prediction in Defined Populations: a simulation study investigating when and how to aggregate existing models (2017)
Journal Article
Mamas. (2017). Clinical Prediction in Defined Populations: a simulation study investigating when and how to aggregate existing models. BMC medical research methodology, 1-11. https://doi.org/10.1186/s12874-016-0277-1

Background
Clinical prediction models (CPMs) are increasingly deployed to support healthcare decisions but they are derived inconsistently, in part due to limited data. An emerging alternative is to aggregate existing CPMs developed for similar sett... Read More about Clinical Prediction in Defined Populations: a simulation study investigating when and how to aggregate existing models.

Impact of Co-morbid burden on mortality in patients with coronary heart disease, heart failure and cerebrovascular accident: a systematic review and meta-analysis (2017)
Journal Article
Mamas, M., & Rashid, M. (2017). Impact of Co-morbid burden on mortality in patients with coronary heart disease, heart failure and cerebrovascular accident: a systematic review and meta-analysis. European Heart Journal - Quality of Care and Clinical Outcomes, 20-36. https://doi.org/10.1093/ehjqcco/qcw025

Aims: We sought to investigate the prognostic impact of co-morbid burden as defined by the Charlson comorbidity index (CCI) in patients with a range of prevalent cardiovascular diseases. Methods & Results: We searched MEDLINE and EMBASE to identify s... Read More about Impact of Co-morbid burden on mortality in patients with coronary heart disease, heart failure and cerebrovascular accident: a systematic review and meta-analysis.