Outputs (15)

Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis (2016)
Journal Article
Wu, P., Shing Kwok, C., Haththotuwa, R., Kotronias, R. A., Babu, A., Fryer, A. A., …Mamas, M. A. (2016). Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis. Diabetologia, 59, 2518-2526. https://doi.org/10.1007/s00125-016-4098-x

Aims/hypothesis: Pre-eclampsia is a pregnancy-specific multi-system disorder and a state of physiological insulin resistance. Our aim is to systematically evaluate and quantify the evidence on the relationship between pre-eclampsia and the future ris... Read More about Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis.

Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer (2016)
Journal Article
Wu. (2016). Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer. Oncotarget, 30844-30858. https://doi.org/10.18632/oncotarget.9602

Cancer cells initially characterized as sensitive to chemotherapy may acquire resistance to chemotherapy and lead to tumor recurrence through the expansion of drug-resistant population. Acquisition of drug resistance to conventional chemotherapy is a... Read More about Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer.

Early pregnancy biomarkers in pre-eclampsia: A systematic review and meta-analysis (2015)
Journal Article
Wu. (2015). Early pregnancy biomarkers in pre-eclampsia: A systematic review and meta-analysis. International Journal of Molecular Sciences, 23035-23056. https://doi.org/10.3390/ijms160923035

Pre-eclampsia (PE) complicates 2%–8% of all pregnancies and is an important cause of perinatal morbidity and mortality worldwide. In order to reduce these complications and to develop possible treatment modalities, it is important to identify women a... Read More about Early pregnancy biomarkers in pre-eclampsia: A systematic review and meta-analysis.

Prothymosin a overexpression contributes to the development of pulmonary emphysema (2013)
Journal Article
Wu. (2013). Prothymosin a overexpression contributes to the development of pulmonary emphysema. Nature communications, https://doi.org/10.1038/ncomms2906

Emphysema is one of the disease conditions that comprise chronic obstructive pulmonary disease. Prothymosin a transgenic mice exhibit an emphysema phenotype, but the pathophysiological role of prothymosin a in emphysema remains unclear. Here we show... Read More about Prothymosin a overexpression contributes to the development of pulmonary emphysema.

Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression (2010)
Journal Article
Wu. (2010). Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression. Cell Research, 434 -444. https://doi.org/10.1038/cr.2010.11

We investigated the ability of fetal mesenchymal stem cells (fMSCs) to differentiate into brown and white adipocytes and compared the expression of a number of marker genes and key regulatory factors. We showed that the expression of key adipocyte re... Read More about Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression.