Outputs (3)

We may not be buying what the label says on the tin: a cautionary tale from a study of the influence of proteoglycans on nerve growth (2017)
Journal Article
Owen, S., Fuller, H., Jones, P., Caterson, B., Shirran, S., Botting, C., & Roberts, S. (2017). We may not be buying what the label says on the tin: a cautionary tale from a study of the influence of proteoglycans on nerve growth. International Journal of Experimental Pathology, 98(3), A4

Introduction

Commercially sourced preparations of reagents are an essential tool for all our laboratory studies and are assumed to have a certain degree of purity. During a study to determine how different proteoglycan substrates might control ner... Read More about We may not be buying what the label says on the tin: a cautionary tale from a study of the influence of proteoglycans on nerve growth.

Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity (2017)
Presentation / Conference
Mennan, C., Owen, S., Garcia, J., McCarthy, H., Banerjee, R., Roberts, S., & Richardson, J. (2017, March). Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity. Poster presented at British Society for Matrix Biology “The Grey Area – Age and the Extracellular Matrix”

Introduction The maintenance of chondrogenic phenotype in human articular chondrocytes grown in continuous normoxic (21% O2) and hypoxic (2% O2) conditions was assessed, with the aim of finding the best environment for culturing cells destined for ca... Read More about Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity.

Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines. (2017)
Journal Article
Owen, S., Sharp, C., Broom, N., McCall, I., Roberts, S., Wade, K., & Rodrigues, S. (2017). Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines. European Spine Journal, 248 -258. https://doi.org/10.1007/s00586-016-4560-y

PURPOSE: To investigate the microscopic fibrous integration between the intervertebral disc, cartilage endplates and vertebral endplates in human lumbar spines of varying degrees of degeneration using differential interference contrast (DIC) optics.... Read More about Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines..