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Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography (2024)
Journal Article
Dimmock, R., Zhang, Y., Butt, G., Rauz, S., Huang, Z., & Yang, Y. (in press). Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography. Journal of Biophotonics, Article e202400172. https://doi.org/10.1002/jbio.202400172

The limbal niche is an adult source of epithelial stem cells which regenerate the cornea epithelium. The architecture and biomechanical properties of the limbus have previously been demonstrated to change due to aging and disease. This study aims to... Read More about Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography.

Distribution, tolerance, growth, behaviour and control methods of <i>Limnoperna fortunei</i> (Dunker, 1857) (Bivalvia: Mytilidae): A review (2024)
Journal Article
Liu, Y., He, X., Yang, Y., Bai, X., & Yuan, C. (2024). Distribution, tolerance, growth, behaviour and control methods of Limnoperna fortunei (Dunker, 1857) (Bivalvia: Mytilidae): A review. Aquatic Conservation: Marine and Freshwater Ecosystems, 34(7), https://doi.org/10.1002/aqc.4217

Limnoperna fortunei (L. fortunei) (Dunker, 1857), the golden mussel, is an invasive species possessing exceptional environmental adaptability and a destructive impact on water systems and artificial structures. To better conservation of freshwater ec... Read More about Distribution, tolerance, growth, behaviour and control methods of <i>Limnoperna fortunei</i> (Dunker, 1857) (Bivalvia: Mytilidae): A review.

A bacteriocin-based coating strategy to prevent vancomycin-resistant Enterococcus faecium biofilm formation on materials of interest for indwelling medical devices. (2024)
Journal Article
Kranjec, C., Mathew, J. P., Ovchinnikov, K., Fadayomi, I., Yang, Y., Kjos, M., & Li, W.-W. (2024). A bacteriocin-based coating strategy to prevent vancomycin-resistant Enterococcus faecium biofilm formation on materials of interest for indwelling medical devices. Biofilm, 8, Article 100211. https://doi.org/10.1016/j.bioflm.2024.100211

The ever-increasing use of exogenous materials as indwelling medical devices in modern medicine offers to pathogens new ways to gain access to human body and begin, in some cases, life threatening infections. Biofouling of such materials with bacteri... Read More about A bacteriocin-based coating strategy to prevent vancomycin-resistant Enterococcus faecium biofilm formation on materials of interest for indwelling medical devices..

Developing a Biomimetic 3D Neointimal Layer as a Prothrombotic Substrate for a Humanized In Vitro Model of Atherothrombosis (2024)
Journal Article
Echrish, J., Pasca, M.-I., Cabrera, D., Yang, Y., & Harper, A. G. S. (2024). Developing a Biomimetic 3D Neointimal Layer as a Prothrombotic Substrate for a Humanized In Vitro Model of Atherothrombosis. Biomimetics, 9(6), Article 372. https://doi.org/10.3390/biomimetics9060372

Acute cardiovascular events result from clots caused by the rupture and erosion of atherosclerotic plaques. This paper aimed to produce a functional biomimetic hydrogel of the neointimal layer of the atherosclerotic plaque that can support thrombogen... Read More about Developing a Biomimetic 3D Neointimal Layer as a Prothrombotic Substrate for a Humanized In Vitro Model of Atherothrombosis.

Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples (2024)
Journal Article
Sharifabad, M. E., Eizadi Sharifabad, M., Soucaille, R., Wang, X., Rotherham, M., Loughran, T., …Telling, N. (2024). Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples. ACS Nano, 18(7), 5297-5310. https://doi.org/10.1021/acsnano.3c08955

The study of exogenous and endogenous nanoscale magnetic material in biology is important for developing biomedical nanotechnology as well as for understanding fundamental biological processes such as iron metabolism and biomineralization. Here, we e... Read More about Optical Microscopy Using the Faraday Effect Reveals in Situ Magnetization Dynamics of Magnetic Nanoparticles in Biological Samples.

Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction (2023)
Journal Article
Dimmock, R. L., Rotherham, M., El Haj, A. J., & Yang, Y. (in press). Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction. Gels, 9(11), Article 915. https://doi.org/10.3390/gels9110915

In the biomedical field, there is a demand for the development of novel approaches for the investigation of optical epithelial anatomical features with biomimetic materials. These materials are not only required to replicate structures but also enabl... Read More about Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction.

Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation (2023)
Journal Article
Lou, T., Bai, X., He, X., Liu, W., Yang, Z., Yang, Y., & Yuan, C. (2023). Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation. Journal of Materials Science, 58, Article 15499–15512

Marine biofouling presents a significant challenge to the sustainable development of the maritime industry. Antimicrobial peptide (AMP) offers a promising strategy to combat biofouling. However, the inherent susceptibility of natural AMPs composed of... Read More about Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation.

Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method (2023)
Journal Article
Wang, X., Cabrera, D., Yang, Y., & Telling, N. (in press). Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method. Frontiers in Nanotechnology, 5, Article 1214313. https://doi.org/10.3389/fnano.2023.1214313

Magnetic nanoparticles (MNPs) are promising as local heat generators for magnetic hyperthermia under AC magnetic fields. The heating efficacy of MNPs is determined by the AC hysteresis loop area, which in turn is affected by the dynamic magnetic prop... Read More about Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method.

Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models (2023)
Journal Article
Ranjbar, J., Njoroge, W., Gibbins, J. M., Roach, P., Yang, Y., & Harper, A. G. S. (2023). Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models. Gels, 9(6), Article 477. https://doi.org/10.3390/gels9060477

Current in vitro thrombosis models utilise simplistic 2D surfaces coated with purified components of the subendothelial matrix. The lack of a realistic humanised model has led to greater study of thrombus formation in in vivo tests in animals. Here w... Read More about Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models.

Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties (2023)
Journal Article
Mason, J. H., Luo, L., Reinwald, Y., Taffetani, M., Hallas-Potts, A., Herrington, C. S., …Bagnaninchi, P. O. (2023). Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties. Communications Biology, 6(1), Article 543. https://doi.org/10.1038/s42003-023-04788-0

The role of the mechanical environment in defining tissue function, development and growth has been shown to be fundamental. Assessment of the changes in stiffness of tissue matrices at multiple scales has relied mostly on invasive and often speciali... Read More about Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties.