Outputs (100)

Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering (2017)
Journal Article
Law, J. X., Liau, L. L., Saim, A., Yang, Y., & Idrus, R. (2017). Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering. Tissue Engineering and Regenerative Medicine, 14(6), 699-718. https://doi.org/10.1007/s13770-017-0075-9

Electrospinning is a simple and versatile technique to fabricate continuous fibers with diameter ranging from micrometers to a few nanometers. To date, the number of polymers that have been electrospun has exceeded 200. In recent years, electrospinni... Read More about Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering.

Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (2017)
Journal Article
Weli, H. K., Akhtar, R., Chang, Z., Li, W., Cooper, J., & Yang, Y. (2017). Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 78-85. https://doi.org/10.1016/j.ejogrb.2017.04.037

Objectives
Non-enzymatic glycation is closely associated with altered mechanical properties of connective tissue. Pregnancy, marked with high levels of female hormones, confers unique alteration to the mechanical properties of pelvic connective tiss... Read More about Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy.

Erratum to: Methods for evaluating medical tests and biomarkers (2017)
Journal Article
Gopalakrishna, G., Investigators, S. C., Langendam, M., Scholten, R., Bossuyt, P., Leeflang, M., …Yang, Y. (2017). Erratum to: Methods for evaluating medical tests and biomarkers. Diagnostic and Prognostic Research, 1(1), https://doi.org/10.1186/s41512-017-0011-4

The original MEMTAB Abstracts in Diagnostic and Prognostic Research contains the incorrect year on individual abstracts in the PDF [1].

“Diagnostic and Prognostic Research 2016” under the correspondence line should therefore have been written as “... Read More about Erratum to: Methods for evaluating medical tests and biomarkers.

Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition. (2017)
Journal Article
Yang, Y. (2017). Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition. Tissue Engineering Part C: Methods, 228 - 236. https://doi.org/10.1089/ten.TEC.2017.0008

Extracellular matrix (ECM) is an essential component of tissues and provides both integrity and biological cues for cells. Collagen is one of the major proteins found within the ECM and therefore is an essential component of all engineered tissues. T... Read More about Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition..

Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy (2017)
Journal Article
Gillies, D., Gamal, W., Downes, A., Reinwald, Y., Yang, Y., El Haj, A., & Bagnaninchi, P. O. (2017). Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy. Proceedings of SPIE, https://doi.org/10.1117/12.2251492

There is an unmet need in tissue engineering for non-invasive, label-free monitoring of cell mechanical behaviour in their physiological environment. Here, we describe a novel optical coherence phase microscopy (OCPM) set-up which can map relative... Read More about Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy.

Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation (2017)
Journal Article
Yang, Y. (2017). Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation. Frontiers in Bioengineering and Biotechnology, 1-11. https://doi.org/10.3389/fbioe.2017.00006

Scaffolds for regenerative medicine applications should instruct cells with the appropriate signals, including biophysical stimuli such as stress and strain, to form the desired tissue. Apart from that, scaffolds, especially for load-bearing applicat... Read More about Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation.

Online Monitoring Of Mechanical Properties Of 3D Tissue Engineered Constructs For Quality Assessment (2016)
Conference Proceeding
El Haj, A. J., Reinwald, Y., Baganinchi, P., Gamal, W., & Yang, Y. (2016). Online Monitoring Of Mechanical Properties Of 3D Tissue Engineered Constructs For Quality Assessment.

Introduction: Monitoring the maturation of engineered tissues prior to implantation into the patient is important for defining quality and manufacturing criteria. Key properties include scaffold integrity and mechanical properties. Novel non-invasive... Read More about Online Monitoring Of Mechanical Properties Of 3D Tissue Engineered Constructs For Quality Assessment.

Biocompatibility of biodegradable medical polymers (2016)
Book Chapter
Ozdil, D., Wimpenny, I., Aydin, H., & Yang, Y. (2017). Biocompatibility of biodegradable medical polymers. . Elsevier. https://doi.org/10.1016/b978-0-08-100372-5.00013-1

Biomaterials have various applications in the medical field; whilst biodegradable biomaterials play an important role in regenerative medicine, tissue engineering and drug delivery. In addition to conversional biocompatibility, biodegradable material... Read More about Biocompatibility of biodegradable medical polymers.

Defining a turnover index for the correlation of biomaterial degradation and cell based extracellular matrix synthesis using fluorescent tagging techniques (2016)
Journal Article
Bardsley, K., Wimpenny, I., Wechsler, R., Shachaf, Y., Yang, Y., & El Haj, A. J. (2016). Defining a turnover index for the correlation of biomaterial degradation and cell based extracellular matrix synthesis using fluorescent tagging techniques. Acta biomaterialia, 45, 133-142. https://doi.org/10.1016/j.actbio.2016.09.002

Non-destructive protocols which can define a biomaterial’s degradation and its associated ability to support proliferation and/or promote extracellular matrix deposition will be an essential in vitro tool. In this study we investigate fluorescently t... Read More about Defining a turnover index for the correlation of biomaterial degradation and cell based extracellular matrix synthesis using fluorescent tagging techniques.

Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. (2016)
Journal Article
Yang, Y. (2016). Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. Regenerative Medicine, 483 - 492. https://doi.org/10.2217/rme-2016-0053

This paper summarizes the proceedings of a workshop held at Trinity Hall, Cambridge to discuss comparability and includes additional information and references to related information added subsequently to the workshop. Comparability is the need to de... Read More about Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015..