Outputs (90)

Study on wear behaviours for NBR/stainless steel under sand water-lubricated conditions (2015)
Journal Article
Dong, C., Yuan, C., Bai, X., Yang, Y., & Yan, X. (2015). Study on wear behaviours for NBR/stainless steel under sand water-lubricated conditions. Wear, 332-333, 1012-1020. https://doi.org/10.1016/j.wear.2015.01.009

Nitrile Butadiene Rubber (NBR) is widely used to make ship water-lubricated rubber stern tube bearings for marine applications. The sand in water is an important factor that affects the tribological properties of the rubber stern tube bearings. This... Read More about Study on wear behaviours for NBR/stainless steel under sand water-lubricated conditions.

Application of new optical coherence elastography to monitor the mineralization processing in bone tissue engineering constructs (2015)
Journal Article
Guan, G., Song, S., Huang, Z., & Yang, Y. (2015). Application of new optical coherence elastography to monitor the mineralization processing in bone tissue engineering constructs. Proceedings of SPIE, https://doi.org/10.1117/12.2078013

Generation of functional tissue in vitro through tissue engineering technique is a promising direction to repair and replace malfunctioned organ and tissue in the modern medicine for various diseases which could not been treated well by conventional... Read More about Application of new optical coherence elastography to monitor the mineralization processing in bone tissue engineering constructs.

Efficient alignment of primary CNS neurites using structurally engineered surfaces and biochemical cues (2015)
Journal Article
Yang. (2015). Efficient alignment of primary CNS neurites using structurally engineered surfaces and biochemical cues. RSC advances, 22053 - 22059 (7). https://doi.org/10.1039/C4RA15739G

Tissue engineering strategies for the central nervous system (CNS) have been largely hampered by the complexity of neural cell interactions and limited ability to control functional circuit formation. Although cultures of primary CNS neurons give key... Read More about Efficient alignment of primary CNS neurites using structurally engineered surfaces and biochemical cues.

Tracking calcification in tissue-engineered bone using synchrotron micro-FTIR and SEM (2014)
Journal Article
Deegan, A. J., Cinque, G., Wehbe, K., Konduru, S., & Yang, Y. (2015). Tracking calcification in tissue-engineered bone using synchrotron micro-FTIR and SEM. Analytical and Bioanalytical Chemistry, 407(4), 1097-1105. https://doi.org/10.1007/s00216-014-8316-4

One novel tissue engineering approach to mimic in vivo bone formation is the use of aggregate or micromass cultures. Various qualitative and quantitative techniques, such as histochemical staining, protein assay kits and RT-PCR, have been used previo... Read More about Tracking calcification in tissue-engineered bone using synchrotron micro-FTIR and SEM.

4-D Hippocampus Measurements of Neurite Growth in vitro (2014)
Conference Proceeding
Dempsey, K., Lam, K., Smith, W., Collins, D., Jones, D. M., Yang, Y., & Richardson, J. (2014). 4-D Hippocampus Measurements of Neurite Growth in vitro. . https://doi.org/10.1109/cit.2014.160

Current research in neural tissue engineering relies heavily on in vivo animal models of neurological injury. This has a number of major drawbacks. Using innovative imaging technologies and allied data analytics, this paper presents our current work... Read More about 4-D Hippocampus Measurements of Neurite Growth in vitro.

A facile in vitro model to study rapid mineralization in bone tissues (2014)
Journal Article
Yang, Y. (2014). A facile in vitro model to study rapid mineralization in bone tissues. BioMedical Engineering OnLine, 136 - ?. https://doi.org/10.1186/1475-925X-13-136

BACKGROUND: Mineralization in bone tissue involves stepwise cell-cell and cell-ECM interaction. Regulation of osteoblast culture microenvironments can tailor osteoblast proliferation and mineralization rate, and the quality and/or quantity of the fin... Read More about A facile in vitro model to study rapid mineralization in bone tissues.

Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy (2014)
Journal Article
Guilbert, M., Eklouh-Molinier, C., Wehbe, K., Sulé-Suso, J., Yang, Y., Cinque, G., …Sockalingum, G. D. (2014). Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy. Journal of Biomedical Optics, 19(11), 111612. https://doi.org/10.1117/1.jbo.19.11.111612

We report here on a first study using synchrotron radiation-based Fourier transform infrared microspectroscopy and imaging to investigate HT1080 human fibrosarcoma cells grown onto different-aged type I collagen networks. Spectral images were analy... Read More about Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy.

Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy (2014)
Journal Article
Rutter, A. V., Siddique, M. R., Filik, J., Sandt, C., Dumas, P., Cinque, G., …Sulé-Suso, J. (2014). Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy. Cytometry Part A, 85(8), 688-697. https://doi.org/10.1002/cyto.a.22488

Over the last few years, significant scientific insight on the effects of chemotherapy drugs at cellular level using synchrotron-based FTIR (S-FTIR) microspectroscopy has been obtained. The work carried out so far has identified spectral differences... Read More about Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy.

Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging (2014)
Journal Article
Smith, W., Lam, K., Dempsey, K., Mazzocchi-Jones, D., Richardson, J., & Yang, Y. (2014). Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging. Proceedings of SPIE, https://doi.org/10.1117/12.2039354

Within the field of tissue engineering there is an emphasis on studying 3-D live tissue structures. Consequently, to investigate and identify cellular activities and phenotypes in a 3-D environment for all in vitro experiments, including shape, migra... Read More about Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging.

An in vitro spinal cord injury model to screen neuroregenerative materials (2014)
Journal Article
Weightman, A. P., Pickard, M. R., Yang, Y., & Chari, D. M. (2014). An in vitro spinal cord injury model to screen neuroregenerative materials. Biomaterials, 35(12), 3756-3765. https://doi.org/10.1016/j.biomaterials.2014.01.022

Implantable ‘structural bridges’ based on nanofabricated polymer scaffolds have great promise to aid spinal cord regeneration. Their development (optimal formulations, surface functionalizations, safety, topographical influences and degradation profi... Read More about An in vitro spinal cord injury model to screen neuroregenerative materials.