Outputs (114)

Acute mechanical overload increases IGF-I and MMP-9 mRNA in 3D tissue-engineered skeletal muscle (2014)
Journal Article
(2014). Acute mechanical overload increases IGF-I and MMP-9 mRNA in 3D tissue-engineered skeletal muscle. Biotechnology Letters, 1113 - 1124. https://doi.org/10.1007/s10529-014-1464-y

Skeletal muscle (SkM) is a tissue that responds to mechanical load following both physiological (exercise) or pathophysiological (bed rest) conditions. The heterogeneity of human samples and the experimental and ethical limitations of animal studies... Read More about Acute mechanical overload increases IGF-I and MMP-9 mRNA in 3D tissue-engineered skeletal muscle.

Evidence of redox-active iron formation following aggregation of ferrihydrite and the Alzheimer's disease peptide ß-amyloid. (2014)
Journal Article
Telling, & Everett. (2014). Evidence of redox-active iron formation following aggregation of ferrihydrite and the Alzheimer's disease peptide ß-amyloid. Inorganic Chemistry, 2803 - 2809. https://doi.org/10.1021/ic402406g

Recent work has demonstrated increased levels of redox-active iron biominerals in Alzheimer's disease (AD) tissue. However, the origin, nature, and role of iron in AD pathology remains unclear. Using X-ray absorption, X-ray microspectroscopy, and ele... Read More about Evidence of redox-active iron formation following aggregation of ferrihydrite and the Alzheimer's disease peptide ß-amyloid..

Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply (2014)
Journal Article
Sugimura, S., Ritter, L. J., Sutton-McDowall, M. L., Mottershead, D. G., Thompson, J. G., & Gilchrist, R. B. (2014). Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply. Molecular Human Reproduction, 20(6), 499-513. https://doi.org/10.1093/molehr/gau013

This study assessed the participation of amphiregulin (AREG) and bone morphogenetic protein 15 (BMP15) during maturation of bovine cumulus-oocyte complexes (COCs) on cumulus cell function and their impact on subsequent embryo development. AREG treatm... Read More about Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply.

Outcomes in patients with acute and stable coronary syndromes: insights from the prospective NOBORI-2 study (2014)
Journal Article
Mamas. (2014). Outcomes in patients with acute and stable coronary syndromes: insights from the prospective NOBORI-2 study. PloS one, e88577 -?. https://doi.org/10.1371/journal.pone.0088577

BACKGROUND: Contemporary data remains limited regarding mortality and major adverse cardiac events (MACE) outcomes in patients undergoing PCI for different manifestations of coronary artery disease. OBJECTIVES: We evaluated mortality and MACE outcome... Read More about Outcomes in patients with acute and stable coronary syndromes: insights from the prospective NOBORI-2 study.

Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis. (2014)
Journal Article
Mamas, M., & Nolan, J. (2014). Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis. Open Heart, e000021 -?. https://doi.org/10.1136/openhrt-2013-000021

OBJECTIVES: To examine the relationship between periprocedural bleeding complications and major adverse cardiovascular events (MACEs) and mortality outcomes following percutaneous coronary intervention (PCI) and study differences in the prognostic im... Read More about Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis..

Feeding and metabolic consequences of scheduled consumption of large, binge-type meals of high fat diet in the Sprague–Dawley rat (2014)
Journal Article
Bake, T., Morgan, D., & Mercer, J. (2014). Feeding and metabolic consequences of scheduled consumption of large, binge-type meals of high fat diet in the Sprague–Dawley rat. Physiology and Behavior, 128, 70-79. https://doi.org/10.1016/j.physbeh.2014.01.018

Providing rats and mice with access to palatable high fat diets for a short period each day induces the consumption of substantial binge-like meals. Temporal food intake structure (assessed using the TSE PhenoMaster/LabMaster system) and metabolic ou... Read More about Feeding and metabolic consequences of scheduled consumption of large, binge-type meals of high fat diet in the Sprague–Dawley rat.

FAST INdiCATE Trial protocol. Clinical efficacy of functional strength training for upper limb motor recovery early after stroke: neural correlates and prognostic indicators. (2014)
Journal Article
Hunter, S. (2014). FAST INdiCATE Trial protocol. Clinical efficacy of functional strength training for upper limb motor recovery early after stroke: neural correlates and prognostic indicators. International Journal of Stroke, 240 -245. https://doi.org/10.1111/ijs.12179

RATIONALE: Functional strength training in addition to conventional physical therapy could enhance upper limb recovery early after stroke more than movement performance therapy plus conventional physical therapy. AIMS: To determine (a) the relative c... Read More about FAST INdiCATE Trial protocol. Clinical efficacy of functional strength training for upper limb motor recovery early after stroke: neural correlates and prognostic indicators..

Changes of synovial fluid protein concentrations in supra-patellar bursitis patients after the injection of different molecular weights of hyaluronic acid (2014)
Journal Article
Chen, C. P., Hsu, C. C., Pei, Y., Chen, R. L., Zhou, S., Shen, H., …Tsai, W. C. (2014). Changes of synovial fluid protein concentrations in supra-patellar bursitis patients after the injection of different molecular weights of hyaluronic acid. Experimental Gerontology, 52, 30-35. https://doi.org/10.1016/j.exger.2014.01.016

Knee pain is commonly seen in orthopedic and rehabilitation outpatient clinical settings, and in the aging population. Bursitis of the knee joint, especially when the volume of the synovial fluid is large enough, can compress and distend the nearby s... Read More about Changes of synovial fluid protein concentrations in supra-patellar bursitis patients after the injection of different molecular weights of hyaluronic acid.

An in vitro spinal cord injury model to screen neuroregenerative materials (2014)
Journal Article
Weightman, A. P., Pickard, M. R., Yang, Y., & Chari, D. M. (2014). An in vitro spinal cord injury model to screen neuroregenerative materials. Biomaterials, 35(12), 3756-3765. https://doi.org/10.1016/j.biomaterials.2014.01.022

Implantable ‘structural bridges’ based on nanofabricated polymer scaffolds have great promise to aid spinal cord regeneration. Their development (optimal formulations, surface functionalizations, safety, topographical influences and degradation profi... Read More about An in vitro spinal cord injury model to screen neuroregenerative materials.

microRNAs as Anti-Cancer Therapy (2014)
Journal Article
Garofalo, M., Di Leva, G., & Croce, C. (2014). microRNAs as Anti-Cancer Therapy. Current Pharmaceutical Design, 20(33), 5328-5335. https://doi.org/10.2174/1381612820666140128211346

MicroRNAs (miRNAs) are endogenously expressed and evolutionarily conserved small non-coding RNAs, which regulate gene expression. Several studies have shown that they are involved in fundamental biological processes, such as proliferation and apoptos... Read More about microRNAs as Anti-Cancer Therapy.