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Outputs (158)

Remote Cell Activation for Bone Regeneration - a Pre Clinical Animal Study (2015)
Journal Article
Markides, H., Telling, N., Henstock, J., & El Haj, A. (2015). Remote Cell Activation for Bone Regeneration - a Pre Clinical Animal Study. Tissue Engineering Part A, 21, S7-S8

We aim to develop a cell-based injectable solution for treatment of non-union bone fractures. Our approach is based on the use of functionalised magnetic particles (MNPs) targeted to the TREK-1 mecho-sensative receptor on the mesenchymal stem cell (M... Read More about Remote Cell Activation for Bone Regeneration - a Pre Clinical Animal Study.

Precision control of dissolved oxygen in mammalian cell culture media impacts on in situ volatile generation and promotes improved mesenchymal stem cell yield accompanied by reduced transcriptional variability (2015)
Journal Article
Mohammad, A. Z., Sule Suso, J., & Forsyth, N. (2015). Precision control of dissolved oxygen in mammalian cell culture media impacts on in situ volatile generation and promotes improved mesenchymal stem cell yield accompanied by reduced transcriptional variability. Free Radical Biology and Medicine, 86(S1), S16. https://doi.org/10.1016/j.freeradbiomed.2015.07.069

Mammalian cell culture is reliant on culture media to support in vitro growth and proliferation. Culture media contains salts, vitamins, and minerals at precise levels where subtle variations result in novel media formulations. Oxygen is a bioactive... Read More about Precision control of dissolved oxygen in mammalian cell culture media impacts on in situ volatile generation and promotes improved mesenchymal stem cell yield accompanied by reduced transcriptional variability.

Engineering In Vitro Differentiation Microenvironments to Study Heart Valve Calcification (2015)
Conference Proceeding
Yang, Y., Bhunia, S., Kontronias, R., Qamar, S., Srinivasan, L., Ipek, T., …Lyu, L. (2015). Engineering In Vitro Differentiation Microenvironments to Study Heart Valve Calcification.

Valvular calcification is one of the most common cardiac conditions affecting the elderly population. The reasons behind the calcification process and the cellular mechanisms involved are not well understood. Valve interstitial cells (VICs) are predo... Read More about Engineering In Vitro Differentiation Microenvironments to Study Heart Valve Calcification.

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow (2015)
Journal Article
Roffe, Yang, & Naire. (2015). In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow. Journal of NeuroInterventional Surgery, 969-972. https://doi.org/10.1136/neurintsurg-2015-011909

BACKGROUND: Mechanical thrombectomy with stent retriever devices is associated with significantly better outcomes than thrombolysis alone in the treatment of acute ischemic stroke. Thrombus aspiration achieves high patency rates, but clinical outcome... Read More about In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow.

Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo (2015)
Journal Article
Taccioli, C., Garofalo, M., Chen, H., Jiang, Y., Tagliazucchi, G. M., Di Leva, G., …Fong, L. Y. (2015). Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo. JNCI: Journal of the National Cancer Institute, 107(11), djv220. https://doi.org/10.1093/jnci/djv220

Background: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency. Using a rat model that recapitulates features of human ESCC,... Read More about Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo.

Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies (2015)
Journal Article
Nolan, Rashid, & Mamas. (2015). Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies. Cardiovascular Revascularization Medicine, 484-490. https://doi.org/10.1016/j.carrev.2015.08.008

Objectives The aim of this study is to review the available literature on the efficacy and safety of agents used for prevention of RAS. Background Different vasodilator agents have been used to prevent radial artery spasm (RAS) in patients under... Read More about Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies.

Oral formulations for paediatrics: palatability studies (2015)
Journal Article
Batchelor, H., Venables, R., Ranmal, S., & Tuleu, C. (2015). Oral formulations for paediatrics: palatability studies. Hospital Pharmacy Europe,

The palatability of paediatric medicines is one of the most important formulation factors with potential to influence adherence to therapeutic regimens and outcomes.1 Palatability has been defined as, “the overall appreciation of a (often oral) medic... Read More about Oral formulations for paediatrics: palatability studies.

Anti-Malarial Activities of Margaritaria discoidea and Other Nigerian Medicinal Plants (2015)
Presentation / Conference
Johnson-Ajinwo, O., Ullah, I., Lee, C., Raman, H., Ellerby, N., Horrocks, P., & Li, W. (2015, August). Anti-Malarial Activities of Margaritaria discoidea and Other Nigerian Medicinal Plants. Paper presented at 2015 PSNA Meeting, University of Illinois at Urbana-Champaign, USA

We previously evaluated in vitro anti-cancer activity of a Nigeria medicinal plant—Margaritaria discoidea (Baill.) G.L.Webster [1]. The aim of current study is to investigate crude extracts of ten medicinal plants including M. discoidea for their ant... Read More about Anti-Malarial Activities of Margaritaria discoidea and Other Nigerian Medicinal Plants.

The potential for virtual worlds in Higher Education: A short literature review (2015)
Journal Article
Voisey. (2015). The potential for virtual worlds in Higher Education: A short literature review

Technology is changing the way University courses are taught; the use of virtual worlds such as Linden Labs Second Life are providing a novel approach to teaching students in a range of disciplines. While few studies are available that assess the qua... Read More about The potential for virtual worlds in Higher Education: A short literature review.