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Outputs (184)

Combined effect of anticancer agents and cytochrome C decorated hybrid nanoparticles for liver cancer therapy (2018)
Journal Article
Al-Shakarci, W., Alsuraifi, A., Abed, M., Abdullah, M., Hoskins, C., Richardson, A., & Curtis, A. (2018). Combined effect of anticancer agents and cytochrome C decorated hybrid nanoparticles for liver cancer therapy. Pharmaceutics, 48. https://doi.org/10.3390/pharmaceutics10020048

Hepatocellular carcinoma is an aggressive form of liver cancer that displays minimal symptoms until its late stages. Unfortunately, patient prognosis still remains poor with only 10% of patients surviving more than five years after diagnosis. Current... Read More about Combined effect of anticancer agents and cytochrome C decorated hybrid nanoparticles for liver cancer therapy.

Managing Clinical Heterogeneity: An Argument for Benefit-Based Action Limits (2018)
Journal Article
(2018). Managing Clinical Heterogeneity: An Argument for Benefit-Based Action Limits. https://doi.org/10.1115/1.4039561

The use of reference ranges is well established in medical practice and research. Classically, a range would be derived from the local healthy population and matched in age, gender, and other characteristics to the patients under investigation. Howev... Read More about Managing Clinical Heterogeneity: An Argument for Benefit-Based Action Limits.

Same-day Inter-Facility Transfer for Percutaneous Coronary Intervention (2018)
Journal Article
Israeli, Z., Lavi, S., Bertand, O. F., & Mamas, M. (2018). Same-day Inter-Facility Transfer for Percutaneous Coronary Intervention. Journal of Interventional Cardiology, 230-235. https://doi.org/10.1111/joic.12486

Background: The use of radial approach for coronary angiography, followed by same-day inter-facility transfer for percutaneous coronary intervention (PCI) has not yet been evaluated. We sought to assess the safety and feasibility of using the transra... Read More about Same-day Inter-Facility Transfer for Percutaneous Coronary Intervention.

Burden of 30-day readmissions after PCI in 824,747 patients in the USA: predictors, causes and cost. Insights from the Nationwide Readmission Database (2018)
Journal Article
Rashid, M., Curzen, N., Nolan, J., Bagur, R., Mamas, M., Potts, J., …Kwok, C. (2018). Burden of 30-day readmissions after PCI in 824,747 patients in the USA: predictors, causes and cost. Insights from the Nationwide Readmission Database. JACC. Cardiovascular interventions, 655-674. https://doi.org/10.1016/j.jcin.2018.01.248

Objectives This study aimed to examine the 30-day unplanned readmissions rate, predictors of readmission, causes of readmissions, and clinical impact of readmissions after percutaneous coronary intervention (PCI). Background Unplanned rehospital... Read More about Burden of 30-day readmissions after PCI in 824,747 patients in the USA: predictors, causes and cost. Insights from the Nationwide Readmission Database.

A Multiple-Model Generalisation of Updating Clinical Prediction Models (2018)
Journal Article
Mamas. (2018). A Multiple-Model Generalisation of Updating Clinical Prediction Models. Statistics in Medicine, 1343-1358. https://doi.org/10.1002/sim.7586

There is growing interest in developing clinical prediction models (CPMs) to aid local healthcare decision-making. Frequently, these CPMs are developed in isolation across different populations, with repetitive de novo derivation a common modelling s... Read More about A Multiple-Model Generalisation of Updating Clinical Prediction Models.

Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial. (2018)
Journal Article
Roffe. (2018). Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial. Translational Stroke Research, 120 -129. https://doi.org/10.1007/s12975-017-0548-0

Post-stroke dysphagia is common, associated with poor outcome and often requires non-oral feeding/fluids. The relationship between route of feeding and outcome, as well as treatment with glyceryl trinitrate (GTN), was studied prospectively. The Effic... Read More about Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial..

Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media (2018)
Journal Article
(2018). Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media. Biomedical Optics Express, 1664 -1679. https://doi.org/10.1364/BOE.9.001664

In vivo imaging of self-illuminating bio-and chemiluminescent reporters is used to observe the physiology of small animals. However, strong light scattering by biological tissues results in poor spatial resolution of the optical imaging, which also d... Read More about Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media.