A novel injectable hydrogel-based drug delivery system for the repair of cartilage defects
(2023)
Presentation / Conference
Outputs (16)
Fabrication of an injectable hydrogel with controllable in situ pore formation for the repair of chondral lesions (2023)
Presentation / Conference
Advanced Hydrogels for Cartilage Tissue Engineering: Recent Progress and Future Directions (2021)
Journal Article
Cartilage is a tension- and load-bearing tissue and has a limited capacity for intrinsic self-healing. While microfracture and arthroplasty are the conventional methods for cartilage repair, these methods are unable to completely heal the damaged tis... Read More about Advanced Hydrogels for Cartilage Tissue Engineering: Recent Progress and Future Directions.
Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications (2021)
Journal Article
Shape memory polymers (SMPs) as a relatively new class of smart materials have gained increasing attention in academic research and industrial developments (e.g., biomedical engineering, aerospace, robotics, automotive industries, and smart textiles)... Read More about Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications.
An empirical model to evaluate the effects of environmental humidity on the formation of wrinkled, creased and porous fibre morphology from electrospinning. (2020)
Journal Article
Controlling environmental humidity level and thus moisture interaction with an electrospinning solution jet has led to a fascinating range of polymer fibre morphological features; these include surface wrinkles, creases and surface/internal porosity... Read More about An empirical model to evaluate the effects of environmental humidity on the formation of wrinkled, creased and porous fibre morphology from electrospinning..
3D-Bioprinting and Micro-/Nano-Technology: Emerging Technologies in Biomedical Sciences (2018)
Journal Article
Codelivery of anti-cancer agents via double-walled polymeric microparticles/injectable hydrogel: A promising approach for treatment of triple negative breast cancer (2017)
Journal Article
Triple negative breast cancer (TNBC) is an aggressive sub-type of breast cancer that rarely responds to conventional chemotherapy. Therefore, novel agents or new routes need to be developed to improve treatment efficacy and diminish severe side-effec... Read More about Codelivery of anti-cancer agents via double-walled polymeric microparticles/injectable hydrogel: A promising approach for treatment of triple negative breast cancer.
Coaxial double-walled microspheres for combined release of cytochrome c and doxorubicin (2017)
Journal Article
Co-axial electrohydrodynamic atomization (CEHDA) can be adapted to fabricate core/shell microspheres with narrow size distribution in a single step for controlled and sustained release of therapeutic drugs [1]. Our previous studies evaluated the adva... Read More about Coaxial double-walled microspheres for combined release of cytochrome c and doxorubicin.
Effective co-delivery of nutlin-3a and p53 genes via core–shell microparticles for disruption of MDM2–p53 interaction and reactivation of p53 in hepatocellular carcinoma (2017)
Journal Article
The tumor suppressor protein p53 is the most frequently inactivated, mutated, or deleted transcriptional factor in tumor cells. Recent studies have shown that the negative regulation of p53 by the murine double minute 2 (MDM2) protein in human cells... Read More about Effective co-delivery of nutlin-3a and p53 genes via core–shell microparticles for disruption of MDM2–p53 interaction and reactivation of p53 in hepatocellular carcinoma.
Enhanced intracellular delivery and controlled drug release of magnetic PLGA nanoparticles modified with transferrin (2017)
Journal Article
Owing to the presence of multidrug resistance in tumor cells, conventional chemotherapy remains clinically intractable. To enhance the therapeutic efficacy of chemotherapeutic agents, targeting strategies based on magnetic polymeric nanoparticles mod... Read More about Enhanced intracellular delivery and controlled drug release of magnetic PLGA nanoparticles modified with transferrin.