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Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications

Zare, Mohadeseh; Davoodi, Pooya; Ramakrishna, Seeram

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Authors

Mohadeseh Zare

Seeram Ramakrishna



Abstract

Shape memory polymers (SMPs) as a relatively new class of smart materials have gained increasing attention in academic research and industrial developments (e.g., biomedical engineering, aerospace, robotics, automotive industries, and smart textiles). SMPs can switch their shape, stiffness, size, and structure upon being exposed to external stimuli. Electrospinning technique can endow SMPs with micro-/nanocharacteristics for enhanced performance in biomedical applications. Dynamically changing micro-/nanofibrous structures have been widely investigated to emulate the dynamical features of the ECM and regulate cell behaviors. Structures such as core-shell fibers, developed by coaxial electrospinning, have also gained potential applications as drug carriers and artificial blood vessels. The clinical applications of micro-/nanostructured SMP fibers include tissue regeneration, regulating cell behavior, cell growth templates, and wound healing. This review presents the molecular architecture of SMPs, the recent developments in electrospinning techniques for the fabrication of SMP micro-/nanofibers, the biomedical applications of SMPs as well as future perspectives for providing dynamic biomaterials structures.

Citation

Zare, M., Davoodi, P., & Ramakrishna, S. (2021). Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications. Nanomaterials, 11(4), 1 - 25. https://doi.org/10.3390/nano11040933

Journal Article Type Article
Acceptance Date Mar 30, 2021
Publication Date Apr 6, 2021
Journal Nanomaterials
Publisher MDPI
Peer Reviewed Peer Reviewed
Volume 11
Issue 4
Pages 1 - 25
DOI https://doi.org/10.3390/nano11040933
Keywords shape memory polymers, electrospinning, molecular architecture, micro-/nanostructures, actuation methods, biomedical applications
Publisher URL https://doi.org/10.3390/nano11040933

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