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Outputs (2202)

Investigating the effects of oxygen tension and electrospun nanofibre topography on the adhesion of embryonic stem cells
Thesis
(2013). Investigating the effects of oxygen tension and electrospun nanofibre topography on the adhesion of embryonic stem cells

Human embryonic stem cells (hESCs) have the potential to differentiate into all cell types of the three germ layers. However, various limitations hinder their use in the clinic, including possibilities of teratoma formation, xenogenic exposure throug... Read More about Investigating the effects of oxygen tension and electrospun nanofibre topography on the adhesion of embryonic stem cells.

Spectropathology for the next generation: Quo vadis?
Journal Article
Byrne, H., Baranska, M., Puppels, G., Stone, N., Wood, B., Gough, K., …Sockalingum, G. (2015). Spectropathology for the next generation: Quo vadis?. Analyst, 2066-2073. https://doi.org/10.1039/C4AN02036G

Although the potential of vibrational spectroscopy for biomedical applications has been well demonstrated, translation into clinical practice has been relatively slow. This Editorial assesses the challenges facing the field and the potential way forw... Read More about Spectropathology for the next generation: Quo vadis?.

Epidrug-mediated reversal of epigenetic changes associated with pituitary adenomas
Thesis
(2013). Epidrug-mediated reversal of epigenetic changes associated with pituitary adenomas

The genesis and outgrowth of pituitary adenomas is consequent to the combined contributions of genetic and epigenetic aberrations. Although the relative contribution of each is not known it is likely that particular aberration may be common or partic... Read More about Epidrug-mediated reversal of epigenetic changes associated with pituitary adenomas.

An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine
Thesis
(2013). An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine

The reduction of bacteria on the skin results in prophylactic and therapeutic benefits by reducing the occurrence of skin infections. Currently, chlorhexidine digluconate, a conventional topical antiseptic, permeates the skin poorly leaving viable op... Read More about An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine.

Investigations into the effects of cholesterol inhibitors on cancer cells in vitro
Thesis
(2014). Investigations into the effects of cholesterol inhibitors on cancer cells in vitro

Cholesterol-rich membrane microdomains have a significant role in cancer progression, particularly in metastasis, and there is evidence that cholesterol inhibitors, most notably statins, can change the behaviour of cancer cells in vitro and in vivo.... Read More about Investigations into the effects of cholesterol inhibitors on cancer cells in vitro.