Skip to main content

Research Repository

Advanced Search

Outputs (88)

Rough and tough. How does silicic acid protect horsetail from fungal infection? (2018)
Journal Article
(2018). Rough and tough. How does silicic acid protect horsetail from fungal infection?. Journal of Trace Elements in Medicine and Biology, 45 - 52. https://doi.org/10.1016/j.jtemb.2018.01.015

Abstract Horsetail (Equisetum arvense) plants grew healthily for 10 weeks under both Si-deficient and Si-replete conditions. After 10 weeks, plants grown under Si-deficient conditions succumbed to fungal infection. We have used NanoSIMS and fluoresce... Read More about Rough and tough. How does silicic acid protect horsetail from fungal infection?.

An Inexpensive, Pulsed, and Multiple Wavelength Bench-Top Light Source for Biological Spectroscopy (2018)
Journal Article
Holman, J., Skidmore, M., & Yates, E. (2018). An Inexpensive, Pulsed, and Multiple Wavelength Bench-Top Light Source for Biological Spectroscopy. Plasma, 1(1), 78-79. https://doi.org/10.3390/plasma1010008

Since signal/noise ratios are proportional to the square root of the intensity, high intensity light sources are advantageous for many forms of UV–Vis and IR spectroscopy particularly with very low or high absorbance samples. We report the constructi... Read More about An Inexpensive, Pulsed, and Multiple Wavelength Bench-Top Light Source for Biological Spectroscopy.

Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection (2018)
Journal Article
Vicenzi, E., Pagani, I., Ghezzi, S., Taylor, S. L., Rudd, T. R., Lima, M. A., …Yates, E. A. (2018). Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection. Biochemical Society Transactions, 46, 609-617. https://doi.org/10.1042/BST20170399

Viruses exploit host metabolic and defence machinery for their own replication. The flaviviruses, which include Dengue (DENV), Yellow Fever (YFV), Japanese Encephalitis (JEV), West Nile (WNV) and Zika (ZIKV) viruses, infect a broad range of hosts, ce... Read More about Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection.

Adsorption of Denaturated Lysozyme at the Air-Water Interface: Structure and Morphology. (2018)
Journal Article
Campbell, R., Tummino, A., Varga, I., Milyaeva, O., Krycki, M., Lin, S., …Noskov, B. (2018). Adsorption of Denaturated Lysozyme at the Air-Water Interface: Structure and Morphology. Langmuir, 5020 - 5029. https://doi.org/10.1021/acs.langmuir.8b00545

The application of protein deuteration and high flux neutron reflectometry has allowed a comparison of the adsorption properties of lysozyme at the air-water interface from dilute solutions in the absence and presence of high concentrations of two st... Read More about Adsorption of Denaturated Lysozyme at the Air-Water Interface: Structure and Morphology..

Critical analysis of reference studies on the toxikinetics of aluminium-based adjuvants (2018)
Journal Article
(2018). Critical analysis of reference studies on the toxikinetics of aluminium-based adjuvants. Journal of Inorganic Biochemistry, 87-95. https://doi.org/10.1016/j.jinorgbio.2017.12.015

We reviewed the three toxicokinetic reference studies commonly used to suggest that aluminum (Al)-based adjuvants are innocuous. A single experimental study was carried out using isotopic 26Al (Flarend et al., Vaccine, 1997). This study used aluminum... Read More about Critical analysis of reference studies on the toxikinetics of aluminium-based adjuvants.

Checks and Balances?: DNA replication and the cell cycle in Plasmodium (2018)
Journal Article
(2018). Checks and Balances?: DNA replication and the cell cycle in Plasmodium. Parasites and Vectors, https://doi.org/10.1186/s13071-018-2800-1

It is over 100 years since the life-cycle of the malaria parasite Plasmodium was discovered, yet its intricacies remain incompletely understood - a knowledge gap that may prove crucial for our efforts to control the disease. Phenotypic screens have p... Read More about Checks and Balances?: DNA replication and the cell cycle in Plasmodium.

Variations in the Peritrophic Matrix Composition of Heparan Sulphate from the Tsetse Fly, Glossina morsitans morsitans (2018)
Journal Article
Rogerson, E., Pelletier, J., Acosta-Serrano, A., Rose, C., Taylor, S., Guimond, S., …Yates, E. (2018). Variations in the Peritrophic Matrix Composition of Heparan Sulphate from the Tsetse Fly, Glossina morsitans morsitans. Pathogens an international, open access journal of pathogens and pathogen-host interactions, 7, https://doi.org/10.3390/pathogens7010032

Tsetse flies are the principal insect vectors of African trypanosomes-sleeping sickness in humans and Nagana in cattle. One of the tsetse fly species, Glossina morsitans morsitans, is host to the parasite, Trypanosoma brucei, a major cause of African... Read More about Variations in the Peritrophic Matrix Composition of Heparan Sulphate from the Tsetse Fly, Glossina morsitans morsitans.

Anti-inflammatory effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against pro-inflammatory cytokine-toxicity in BRIN-BD11 cells. (2018)
Presentation / Conference
Watson. (2018, March). Anti-inflammatory effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against pro-inflammatory cytokine-toxicity in BRIN-BD11 cells. Poster presented at Diabetes UK Professional Conference 2018, London ExCeL, London

Introduction: CYP450-derived EETs display anti-inflammatory activity in cardiac models of inflammation, in part through activation of Peroxisome proliferator-activated receptor gamma (PPARγ) and inhibition of Nuclear Factor kappa B (NF-kB) activation... Read More about Anti-inflammatory effects of epoxyeicosatrienoic acids (EETs) and their corresponding diols against pro-inflammatory cytokine-toxicity in BRIN-BD11 cells..