The perplexing PEXEL protein secretory pathway

Russo

Abstract

Plasmodium parasites possess a unique PEXEL sorting pathway to deliver secretory proteins into the host cells in which they reside. A new study shows the existence of independent sorting/entry complexes to detect and deliver PEXEL proteins into the parasite endoplasmic reticulum.

• Acceptance Date: Aug 24, 2018
• Publication Date: Aug 24, 2018
• Journal: Nature Reviews Microbiology
• Print ISSN: 1740-1526
• Publisher: Nature Publishing Group
• Pages: 969 - 970
• DOI: https://doi.org/10.1038/s41564-018-0235-2
• Keywords: malaria; parasite biology; parasite physiology
• Publisher URL: https://www.nature.com/articles/s41564-018-0235-2#article-info