The invasive investigation of INOCA in the coronary catheterization lab

Burgess, Sonya N.; Mamas, Mamas A.

Abstract

Over half of all patients with angina have no angiographically demonstratable obstructive coronary disease, with a significant proportion of these patients having undiagnosed microvascular dysfunction and/or vasospastic angina. In chronic coronary syndrome, ischemia with non -obstructive coronary artery disease (INOCA) often remains undiagnosed, or uninvestigated. INOCAmay occur due to vasospastic angina and microvascular dysfunction and require invasive assessment in the coronary catheterization lab. To evaluate INOCA coronary flow reserve (CFR) and the index of microcirculatory resistance (IMR) are used to assess microvascular dysfunction before acetylcholine provocation testing for coronary spasm. This review provides an overview of the invasive investigation of INOCA in the coronary catheterization lab for patients with angina to be optimally managed.

Citation

Burgess, S. N., & Mamas, M. A. (2024). The invasive investigation of INOCA in the coronary catheterization lab. American Heart Journal Plus: Cardiology Research and Practice, 38, Article 100365. https://doi.org/10.1016/j.ahjo.2024.100365

• Journal Article Type: Article
• Acceptance Date: Jan 17, 2024
• Online Publication Date: Jan 19, 2024
• Publication Date: 2024-02
• Deposit Date: Mar 18, 2024
• Journal: American Heart Journal Plus: Cardiology Research and Practice
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Article Number: 100365
• DOI: https://doi.org/10.1016/j.ahjo.2024.100365
• Keywords: General Medicine; General Chemistry
• Additional Information: This article is maintained by: Elsevier; Article Title: The invasive investigation of INOCA in the coronary catheterization lab; Journal Title: American Heart Journal Plus: Cardiology Research and Practice; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.ahjo.2024.100365; Content Type: article; Copyright: © 2024 The Authors. Published by Elsevier Inc.