Predictors of outcome in psychological therapy for co-morbid long-term health conditions and common mental health problems: an observation cohort study (2025)
Thesis
McDonald, J. A. E. Predictors of outcome in psychological therapy for co-morbid long-term health conditions and common mental health problems: an observation cohort study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1109374

Co-morbid long-term conditions (LTCs) and common mental health problems are highly prevalent and continue to be associated with poorer health and social outcomes. Recent policy frameworks have endorsed the need to expand mental health provision for p... Read More about Predictors of outcome in psychological therapy for co-morbid long-term health conditions and common mental health problems: an observation cohort study.

Application and development of statistical methods for prediction modelling in healthcare research (2025)
Thesis
Archer, L. Application and development of statistical methods for prediction modelling in healthcare research. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1109632

This thesis explores methods and applications for prediction modelling in a healthcare setting, focusing on continuous outcomes, sample size, and external validation of model performance.

It begins by discussing current practices around the dicho... Read More about Application and development of statistical methods for prediction modelling in healthcare research.

Health outcomes from child marriages in humanitarian settings (2025)
Thesis
Srinivas, S. Health outcomes from child marriages in humanitarian settings. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1109613

Background Globally, it is predicted that there are 640 million girls and women around the world, alive today, who were married off in childhood. Evidence shows that there is an increase in the prevalence of child marriages during humanitarian crises... Read More about Health outcomes from child marriages in humanitarian settings.

A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome (2025)
Journal Article
Harrington, G. M. B., Cool, P., Hulme, C., Stokes-Fisher, J., Peffers, M., El Masri, W., Osman, A., Chowdhury, J. R., Kumar, N., Budithi, S., & Wright, K. (2025). A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome. Journal of Neurotrauma, 42(3-4), https://doi.org/10.1101/2022.07.12.499696

Spinal cord injury (SCI) is a major cause of disability, with complications postinjury often leading to lifelong health issues with the need for extensive treatment. Neurological outcome post-SCI can be variable and difficult to predict, particularly... Read More about A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome.

Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial (2025)
Journal Article
Sze, S., Squire, I., Kalra, P. R., Cleland, J. G., Petrie, M. C., Kalra, P. A., Ahmed, F., Banerjee, P., Boos, C. J., Chapman, C., Cowburn, P. J., Dixon, L., Duckett, S., Lane, R., Foley, P., Lang, N. N., Lyons, K., Ray, R., Schiff, R., Thomson, E. A., …Ford, I. (2025). Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial. Heart, heartjnl-2024-324908. https://doi.org/10.1136/heartjnl-2024-324908

Background: Intravenous iron therapy with ferric derisomaltose (FDI) has been shown to improve outcomes in patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency. However, its effects across different age groups remain... Read More about Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial.

Understanding women from ethnic minorities’ perspectives about contraception in the UK: a qualitative study using a participatory action research approach with community research link workers (2025)
Journal Article
Linton, E., Mawson, R. L., Cory, R. J., Ma, R., Fryer, K., Aminu, H., Aslam, A., Nabage, F. N., Daley, S., & Mitchell, C. A. (2025). Understanding women from ethnic minorities’ perspectives about contraception in the UK: a qualitative study using a participatory action research approach with community research link workers. BMJ Sexual & Reproductive Health, https://doi.org/10.1136/bmjsrh-2024-202522

Background: Contraception has revolutionised women’s health, enabling planned pregnancies and improved outcomes for mothers and babies. However, disparities exist in rates of unintended pregnancies and contraceptive uptake among ethnic groups. The re... Read More about Understanding women from ethnic minorities’ perspectives about contraception in the UK: a qualitative study using a participatory action research approach with community research link workers.

Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology (2025)
Journal Article
Erbay, M. I., Manubolu, V. S., Stein-Merlob, A. F., Ferencik, M., Mamas, M. A., Lopez-Mattei, J., Baldassarre, L. A., Budoff, M. J., & Yang, E. H. (2025). Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology. Current Cardiology Reports, 27(1), 51. https://doi.org/10.1007/s11886-025-02206-x

Purpose of Review: Cardiovascular computed tomography (CCT) is a versatile, readily available, and non-invasive imaging tool with high-resolution capabilities in many cardiovascular diseases (CVD). Our review explains the increased risk of CVD among... Read More about Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology.

Temperature-controlled Ablation Versus Conventional Ablation for Pulmonary Vein Isolation in the Treatment of AF: A Systematic Review and Meta-Analysis (2025)
Journal Article
Clay, B., Sokhal, B. S., Zeriouh, S., Srinivasan, N. T., Gajendragadkar, P. R., & Martin, C. A. (2025). Temperature-controlled Ablation Versus Conventional Ablation for Pulmonary Vein Isolation in the Treatment of AF: A Systematic Review and Meta-Analysis. Arrhythmia and Electrophysiology Review, 14, https://doi.org/10.15420/aer.2024.41

Background: This study compared the efficacy and safety of temperature-controlled and conventional contact-force-sensing radiofrequency ablation catheters for pulmonary vein isolation (PVI) in AF. Methods: Seven studies (1,138 patients) were included... Read More about Temperature-controlled Ablation Versus Conventional Ablation for Pulmonary Vein Isolation in the Treatment of AF: A Systematic Review and Meta-Analysis.

Autologous Peripheral Blood-Derived Orthobiologics for the Management of Elbow Disorders: A Review of Current Clinical Evidence. (2025)
Journal Article
Gupta, A., Migliorini, F., Bardazzi, T., & Maffulli, N. (2025). Autologous Peripheral Blood-Derived Orthobiologics for the Management of Elbow Disorders: A Review of Current Clinical Evidence. Pain and Therapy, https://doi.org/10.1007/s40122-025-00707-9

Elbow ailments are common, but conventional treatment modalities have shortcomings, offering only interim pain relief rather than targeting the underlying pathophysiology. The last two decades have seen a marked increase in the use of autologous peri... Read More about Autologous Peripheral Blood-Derived Orthobiologics for the Management of Elbow Disorders: A Review of Current Clinical Evidence..

Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review: Quality Indicators for MSK Conditions. (2024)
Journal Article
Braybrooke, A., Baraks, K., Burgess, R., Banerjee, A., & Hill, J. (in press). Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review: Quality Indicators for MSK Conditions. Archives of Physical Medicine and Rehabilitation, https://doi.org/10.1016/j.apmr.2024.08.022

To identify, appraise, and synthesise common themes from quality indicator (QI) sets designed for the assessment, management, and rehabilitation of musculoskeletal conditions in primary and community care contexts. A systematic search was performed o... Read More about Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review: Quality Indicators for MSK Conditions..

The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. (2024)
Journal Article
Galimzhanov, A., Tun, H. N., Sabitov, Y., Perone, F., Kursat, T. M., Tenekecioglu, E., & Mamas, M. A. (in press). The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. European Journal of Clinical Investigation, Article e14295. https://doi.org/10.1111/eci.14295

Mean platelet volume (MPV) is a widely available laboratory index, however its prognostic significance in patients with coronary artery disease (CAD) is still unclear. We intended to investigate and pool the evidence on the prognostic utility of admi... Read More about The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses..

Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk (2024)
Journal Article
Farooq, S., Xu, L., Ullah, S., Li, J., Nie, J., Ping, J., & Ying, Y. (2024). Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk. Comprehensive Reviews in Food Science and Food Safety, 23(4), Article e13399. https://doi.org/10.1111/1541-4337.13399

AbstractMilk, as a widely consumed nutrient‐rich food, is crucial for bone health, growth, and overall nutrition. The persistent application of veterinary drugs for controlling diseases and heightening milk yield has imparted substantial repercussion... Read More about Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk.

How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress? (2024)
Thesis
Awan, H. How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress?. (Thesis). Keele University. https://keele-repository.worktribe.com/output/849807

People with physical-mental comorbidity have a poorer quality of life, worse clinical outcomes and increased mortality than those with physical conditions alone. Those from some ethnic groups may be less likely to recognise and seek help for symptoms... Read More about How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress?.

Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review. (2024)
Journal Article
Amini-Salehi, E., Mahapatro, A., Korsapati, R. R., Korsapati, A. R., Jain, S. M., Babaeizad, A., Mohammadi, S., Rashidian, P., Hashemi, M., Dave, T., Jamilian, P., Hassanipour, S., Keivanlou, M.-H., & Patel, D. (in press). Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review. Nutrition, Metabolism and Cardiovascular Diseases, https://doi.org/10.1016/j.numecd.2024.05.017

Given the epidemic proportions of type 2 diabetes mellitus (T2DM) globally, it's crucial to comprehensively understand the factors influencing its management. The gut microbiome, known for its influence on various aspects of health, has emerged as a... Read More about Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review..

How common are side effects of treatment to prevent gout flares when starting allopurinol? (2024)
Journal Article
Saul, H., Deeney, B., Swaithes, L., & Roddy, E. (in press). How common are side effects of treatment to prevent gout flares when starting allopurinol?. BMJ, 384, Article q514. https://doi.org/10.1136/bmj.q514

The studyRoddy E, Bajpai R, Forrester H, et al. Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink. 2023;82:1618-25.To re... Read More about How common are side effects of treatment to prevent gout flares when starting allopurinol?.

How do medical schools influence their students’ career choices? A realist evaluation (2024)
Journal Article
Thomas, A., Kinston, R., Yardley, S., McKinley, R. K., & Lefroy, J. (2024). How do medical schools influence their students’ career choices? A realist evaluation. Medical Education Online, 29(1), https://doi.org/10.1080/10872981.2024.2320459

Introduction
The career choices of medical graduates vary widely between medical schools in the UK and elsewhere and are generally not well matched with societal needs. Research has found that experiences in medical school including formal, informal... Read More about How do medical schools influence their students’ career choices? A realist evaluation.

Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T). (2024)
Journal Article
Miranda, R. N., Qiu, F., Manoragavan, R., Austin, P. C., Naimark, D. M. J., Fremes, S. E., Ko, D. T., Madan, M., Mamas, M. A., Sud, M. K., Tam, D., & Wijeysundera, H. C. (2024). Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T). Journal of the American Heart Association, 13(5), Article e033768. https://doi.org/10.1161/JAHA.123.033768

Transcatheter aortic valve implantation (TAVI) has seen indication expansion and thus exponential growth in demand over the past decade. In many jurisdictions, the growing demand has outpaced capacity, increasing wait times and preprocedural adverse... Read More about Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T)..

Global primary care research challenges (2024)
Journal Article
Akhtar, S., Poppleton, A., & Caleyachetty, R. (in press). Global primary care research challenges. InnovAiT: Education and inspiration for general practice, https://doi.org/10.1177/17557380231225590

Healthcare needs are changing globally as people live longer, but not necessarily in better health. Increased population migration is leading to culturally diverse patient populations with more diverse health needs and expectations. The provision of... Read More about Global primary care research challenges.

The invasive investigation of INOCA in the coronary catheterization lab (2024)
Journal Article
Burgess, S. N., & Mamas, M. A. (2024). The invasive investigation of INOCA in the coronary catheterization lab. American Heart Journal Plus: Cardiology Research and Practice, 38, Article 100365. https://doi.org/10.1016/j.ahjo.2024.100365

Over half of all patients with angina have no angiographically demonstratable obstructive coronary disease, with a significant proportion of these patients having undiagnosed microvascular dysfunction and/or vasospastic angina. In chronic coronary sy... Read More about The invasive investigation of INOCA in the coronary catheterization lab.

The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study (2023)
Thesis
O'Brien, A. V. The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674475

Background: Polymyalgia Rheumatica (PMR) is the commonest rheumatic condition affecting older people, typically treated with glucocorticoids. However, the treatment side-effects including fatigue, anxiety and other alterations in mood, are frequent a... Read More about The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study.