Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review: Quality Indicators for MSK Conditions. (2024)
Journal Article
Braybrooke, A., Baraks, K., Burgess, R., Banerjee, A., & Hill, J. (in press). Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review: Quality Indicators for MSK Conditions. Archives of Physical Medicine and Rehabilitation, https://doi.org/10.1016/j.apmr.2024.08.022

To identify, appraise, and synthesise common themes from quality indicator (QI) sets designed for the assessment, management, and rehabilitation of musculoskeletal conditions in primary and community care contexts. A systematic search was performed o... Read More about Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review: Quality Indicators for MSK Conditions..

The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. (2024)
Journal Article
Galimzhanov, A., Tun, H. N., Sabitov, Y., Perone, F., Kursat, T. M., Tenekecioglu, E., & Mamas, M. A. (in press). The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. European Journal of Clinical Investigation, Article e14295. https://doi.org/10.1111/eci.14295

Mean platelet volume (MPV) is a widely available laboratory index, however its prognostic significance in patients with coronary artery disease (CAD) is still unclear. We intended to investigate and pool the evidence on the prognostic utility of admi... Read More about The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses..

Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk (2024)
Journal Article
Farooq, S., Xu, L., Ullah, S., Li, J., Nie, J., Ping, J., & Ying, Y. (2024). Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk. Comprehensive Reviews in Food Science and Food Safety, 23(4), Article e13399. https://doi.org/10.1111/1541-4337.13399

AbstractMilk, as a widely consumed nutrient‐rich food, is crucial for bone health, growth, and overall nutrition. The persistent application of veterinary drugs for controlling diseases and heightening milk yield has imparted substantial repercussion... Read More about Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk.

How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress? (2024)
Thesis
Awan, H. (2024). How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress?. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/849807

People with physical-mental comorbidity have a poorer quality of life, worse clinical outcomes and increased mortality than those with physical conditions alone. Those from some ethnic groups may be less likely to recognise and seek help for symptoms... Read More about How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress?.

Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review. (2024)
Journal Article
Amini-Salehi, E., Mahapatro, A., Korsapati, R. R., Korsapati, A. R., Jain, S. M., Babaeizad, A., …Patel, D. (in press). Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review. Nutrition, Metabolism and Cardiovascular Diseases, https://doi.org/10.1016/j.numecd.2024.05.017

Given the epidemic proportions of type 2 diabetes mellitus (T2DM) globally, it's crucial to comprehensively understand the factors influencing its management. The gut microbiome, known for its influence on various aspects of health, has emerged as a... Read More about Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review..

How common are side effects of treatment to prevent gout flares when starting allopurinol? (2024)
Journal Article
Saul, H., Deeney, B., Swaithes, L., & Roddy, E. (in press). How common are side effects of treatment to prevent gout flares when starting allopurinol?. BMJ, 384, Article q514. https://doi.org/10.1136/bmj.q514

The studyRoddy E, Bajpai R, Forrester H, et al. Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink. 2023;82:1618-25.To re... Read More about How common are side effects of treatment to prevent gout flares when starting allopurinol?.

How do medical schools influence their students’ career choices? A realist evaluation (2024)
Journal Article
Thomas, A., Kinston, R., Yardley, S., McKinley, R. K., & Lefroy, J. (2024). How do medical schools influence their students’ career choices? A realist evaluation. Medical Education Online, 29(1), https://doi.org/10.1080/10872981.2024.2320459

Introduction
The career choices of medical graduates vary widely between medical schools in the UK and elsewhere and are generally not well matched with societal needs. Research has found that experiences in medical school including formal, informal... Read More about How do medical schools influence their students’ career choices? A realist evaluation.

Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T). (2024)
Journal Article
Miranda, R. N., Qiu, F., Manoragavan, R., Austin, P. C., Naimark, D. M. J., Fremes, S. E., …Wijeysundera, H. C. (2024). Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T). Journal of the American Heart Association, 13(5), Article e033768. https://doi.org/10.1161/JAHA.123.033768

Transcatheter aortic valve implantation (TAVI) has seen indication expansion and thus exponential growth in demand over the past decade. In many jurisdictions, the growing demand has outpaced capacity, increasing wait times and preprocedural adverse... Read More about Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T)..

Global primary care research challenges (2024)
Journal Article
Akhtar, S., Poppleton, A., & Caleyachetty, R. (in press). Global primary care research challenges. InnovAiT: Education and inspiration for general practice, https://doi.org/10.1177/17557380231225590

Healthcare needs are changing globally as people live longer, but not necessarily in better health. Increased population migration is leading to culturally diverse patient populations with more diverse health needs and expectations. The provision of... Read More about Global primary care research challenges.

The invasive investigation of INOCA in the coronary catheterization lab (2024)
Journal Article
Burgess, S. N., & Mamas, M. A. (2024). The invasive investigation of INOCA in the coronary catheterization lab. American Heart Journal Plus: Cardiology Research and Practice, 38, Article 100365. https://doi.org/10.1016/j.ahjo.2024.100365

Over half of all patients with angina have no angiographically demonstratable obstructive coronary disease, with a significant proportion of these patients having undiagnosed microvascular dysfunction and/or vasospastic angina. In chronic coronary sy... Read More about The invasive investigation of INOCA in the coronary catheterization lab.

Recreating arterial thrombosis models using tissue-engineered arterial constructs: A method to reduce and replace mice used in platelet research (2023)
Thesis
Ranjbar, J. A. (2023). Recreating arterial thrombosis models using tissue-engineered arterial constructs: A method to reduce and replace mice used in platelet research. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/674551

Intravital microscopy in mice is widely used to study in vivo thrombus formation, however, the relevance of these studies to human physiology is unclear. In this thesis, a 3D tissue-engineered human arterial construct (TEAC) was developed that replic... Read More about Recreating arterial thrombosis models using tissue-engineered arterial constructs: A method to reduce and replace mice used in platelet research.

The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study (2023)
Thesis
O'Brien, A. V. (2023). The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/674475

Background: Polymyalgia Rheumatica (PMR) is the commonest rheumatic condition affecting older people, typically treated with glucocorticoids. However, the treatment side-effects including fatigue, anxiety and other alterations in mood, are frequent a... Read More about The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study.

An immersive online response to a practical problem (2023)
Journal Article
Jones, S., & Jones, G. (2023). An immersive online response to a practical problem. The Journal of Academic Development and Education, https://doi.org/10.21252/na3v-ag62

COVID-19 has led to shortages of clinical placements across academia, felt strongly within the School of Allied Health Professions (SAHP) who lost 12 placements in September and 73 placements in November 2020. To counteract this loss, SAHP and govern... Read More about An immersive online response to a practical problem.

Training healthcare professionals to be ready for practice in an era of social distancing: A realist evaluation (2023)
Journal Article
Lefroy, J., Bialan, J., Moult, A., Hay, F., Stapleton, C., Thompson, J., …Cope, N. (2023). Training healthcare professionals to be ready for practice in an era of social distancing: A realist evaluation. Advances in Health Sciences Education, https://doi.org/10.1007/s10459-023-10297-w

Background
Programme changes due to the COVID-19 pandemic have impacted variably on preparation for practice of healthcare professional students. Explanations for such variability need exploration. The aim of our study was to understand what clinica... Read More about Training healthcare professionals to be ready for practice in an era of social distancing: A realist evaluation.

Association of frailty status with the causes, characteristics and outcomes of patients with cardiovascular disease using electronic health record data (2023)
Thesis
Sokhal, B. S. (2023). Association of frailty status with the causes, characteristics and outcomes of patients with cardiovascular disease using electronic health record data. (Thesis). Keele University

Introduction
Cardiovascular disease (CVD) is the commonest cause of morbidity and mortality worldwide. Frailty is a clinical syndrome of physiological decline, resulting in adverse health outcomes. While the bidirectional relationship between CVD a... Read More about Association of frailty status with the causes, characteristics and outcomes of patients with cardiovascular disease using electronic health record data.

Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study (2023)
Thesis
Ghosal, S. (2023). Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study. (Thesis). Keele University

Introduction
The incidence of type 2 Diabetes mellitus (T2DM) is increasing and is a major public health burden. Obesity is one of the main modifiable risk factors for T2DM. However no UK studies have assessed the relationship of orlistat, a medica... Read More about Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study.

Evidence Based Practice: Medical Education Research (2023)
Book Chapter
Rees. (2023). Evidence Based Practice: Medical Education Research. In Family medicine in the undergraduate curriculum: preparing medical students to work in evolving health care systems. Taylor & Francis (Routledge)

Subtalar joint moments of children with cerebral palsy (2023)
Journal Article
Meilak, E., Modenese, L., Andrew, R., Julie, S., Edward, C., & Stewart, C. (in press). Subtalar joint moments of children with cerebral palsy. Gait & Posture, 106, S121. https://doi.org/10.1016/j.gaitpost.2023.07.151

Introduction
Children with cerebral palsy (CP) often develop foot deformities [1], such as equinovarus, planovalgus non-midfoot break (PNMFB) and midfoot break (MFB) [2]. The aetiology of the development and progr... Read More about Subtalar joint moments of children with cerebral palsy.

Care, Violence, and More-Than-Human Reproductive Ecologies in North India (2023)
Journal Article
Fiks, E. (2023). Care, Violence, and More-Than-Human Reproductive Ecologies in North India. Ethnos, 1-17. https://doi.org/10.1080/00141844.2023.2243398

This paper explores therapeutic interventions for subfertility as a domain where meanings and boundaries of care and violence are constituted. It centres around a fragment of one Rajasthani woman’s reproductive journey contextualised within marriage... Read More about Care, Violence, and More-Than-Human Reproductive Ecologies in North India.

The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin (2023)
Thesis
Sandhu, K. S. (2023). The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin. (Thesis). Keele University

The following thesis began by discussing current controversies surrounding EPC identification then studied the effect of atorvastatin on EPC numbers in bench and bed side studies.
Atorvastatin was hypothesised to increase chemokine CXCL-12 its recep... Read More about The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin.