Using video-based examiner score comparison and adjustment (VESCA) to compare the influence of examiners at different sites in a distributed objective structured clinical exam (OSCE) (2023)
Purpose: Ensuring equivalence of examiners’ judgements within distributed objective structured clinical exams (OSCEs) is key to both fairness and validity but is hampered by lack of cross-over in the performances which different groups of examiners o... Read More about Using video-based examiner score comparison and adjustment (VESCA) to compare the influence of examiners at different sites in a distributed objective structured clinical exam (OSCE).
Background: Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly ta... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.
Background Radial access is associated with improved outcomes following percutaneous coronary intervention (PCI); however, its role in complex, high-risk percutaneous coronary intervention (CHiP) remains poorly studied. Methods We studied retros... Read More about Complex high‐risk percutaneous coronary intervention types, trends, and outcomes according to vascular access site.
BackgroundPatients established on thiopurines (e.g., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These side-effects are uncommon during long-term treatment. We develo... Read More about Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation..
Introduction Facioscapulohumeral dystrophy (FSHD) can affect upper-limb function through muscle degeneration, fatty infiltration and oedema. Muscle echogenicity, measured using ultrasound, could be used as a bioma... Read More about Quantifying morphological changes in middle trapezius with ultrasound scanning and a novel histogram matching algorithm.
We would like to draw attention to evidence of substantial bias in the article published in this journal by Jack et al. (BMC Med 18:1-12, 2020). They provide an analysis of antidepressant prescribing to children and young people (CYP; ages 5 to 17) i... Read More about Substantially more children receiving antidepressants see a specialist than reported by Jack et al..
IMPORTANCE Emerging evidence has consistently demonstrated that sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of heart failure (HF) hospitalization and cardiovascular (CV) death among patients with HF. However, it remains unclear... Read More about Time to Benefit of Sodium-Glucose Cotransporter-2 Inhibitors Among Patients With Heart Failure.
General Practice has changed over the past decade. Expansion of clinicians' roles may create uncertainty, stress, and overload - particular for those at the start of their career. The WONCA Europe network for medical education, EURACT, has published... Read More about What competencies do European general practice trainees value the most? A prioritisation exercise using a Delphi-informed approach.
Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Objectives: In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untre... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.
Gout is associated with an increased risk of both physical-health co-morbidities and a reduction in physical health-related quality of life. However, the association between gout and psychological comorbidity (depression and anxiety) has received lit... Read More about The association between gout and psychological co-morbidity: results from a prospective cohort study.
The serine/threonine protein phosphatase 4 holoenzyme consists of PP4 catalytic subunit (PP4c), which interacts with four different regulatory subunits (PP4R1, PP4R2, PP4R3, PP4R4). Previous studies have shown that PP4c acts as a tumour suppressor an... Read More about An investigation into the functional roles of protein phosphatase 4 regulatory subunits PP4R3A and PP4R3B in leukemic T-cells.
Penetrating traumatic brain injury (pTBI) remains one of the leading causes of death in the younger population in the UK, as no clinical regenerative therapies are available. Experimental therapies currently being screened for efficacy are wide rangi... Read More about Developing tools for inter-site transport of brain tissue models in tissue engineering research.
Introduction Frozen shoulder, a condition that can cause prolonged pain and disability, has previously been found to be common amongst people with diabetes. This thesis aimed to improve the understanding of the nature of the relationship between dia... Read More about Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records.
Background: Greater understanding of NQNs’ perceptions of their pre-registration and transition experiences, and influences on their perceptions can inform pre-registration curricula and preceptorship programmes to support a positive transition to qu... Read More about Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity.
Background Polymyalgia rheumatica (PMR) causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient’s perspective is vital to highquality research and patient-centred care, yet there are no validated... Read More about Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica.
Coronary heart disease is the primary global cause of morbidity and mortality, accounting for about 33% of global deaths in 2013. Atherosclerosis is the principal cause of coronary heart disease and is caused by inflammation of the arterial wall. Thi... Read More about Developing a 3D tissue-engineered model to study the biology and treatment of atherosclerosis.
Introduction Cardiopulmonary impairments are the leading cause of morbidity and mortality in advanced stages of Parkinson’s. Although there is some evidence of pulmonary impairments in the earlier stages, symptoms remain asymptomatic until advanced... Read More about Aerobic exercise to improve cardiorespiratory function in Parkinson's.
Background: There are a range of data collection methodologies employed for collecting patient health related research data. Within primary care settings, and particularly within general practice, time and resources are limited. The utility of an aut... Read More about Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice.
Self-harm in young people is a national priority. General practitioners see young people who self-harm the most often in the National Health Service (NHS), and episodes of self-harm in young people presenting to general practice are rising. General p... Read More about Examining the potential of general practice to support young people with self-harm behaviour: a systematic review and qualitative study.
Showing 1 - 20 of 130 results