All Outputs (4)

miRNA clusters as therapeutic targets for hormone-resistant breast cancer (2015)
Journal Article
Di Leva, G., Cheung, D. G., & Croce, C. M. (2015). miRNA clusters as therapeutic targets for hormone-resistant breast cancer. Expert Review of Endocrinology and Metabolism, 10(6), 607-617. https://doi.org/10.1586/17446651.2015.1099430

MicroRNAs are small non-coding RNAs that typically inhibit the translation and stability of messenger RNAs, controlling genes involved in cellular processes such as inflammation, cell cycle regulation, stress response, differentiation, apoptosis, and... Read More about miRNA clusters as therapeutic targets for hormone-resistant breast cancer.

Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo (2015)
Journal Article
Taccioli, C., Garofalo, M., Chen, H., Jiang, Y., Tagliazucchi, G. M., Di Leva, G., …Fong, L. Y. (2015). Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo. JNCI: Journal of the National Cancer Institute, 107(11), djv220. https://doi.org/10.1093/jnci/djv220

Background:
Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency. Using a rat model that recapitulates features of human ESCC,... Read More about Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo.

A set of NF-?B-regulated microRNAs induces acquired TRAIL resistance in lung cancer. (2015)
Journal Article
Jeon, Y., Middleton, J., Kim, T., Laganà, A., Piovan, C., Secchiero, P., …Croce, C. M. (2015). A set of NF-?B-regulated microRNAs induces acquired TRAIL resistance in lung cancer. Proceedings of the National Academy of Sciences of the United States of America, 112(26), E3355 - E3364. https://doi.org/10.1073/pnas.1504630112

TRAIL (TNF-related apoptosis-inducing ligand) is a promising anticancer agent that can be potentially used as an alternative or complementary therapy because of its specific antitumor activity. However, TRAIL can also stimulate the proliferation of c... Read More about A set of NF-?B-regulated microRNAs induces acquired TRAIL resistance in lung cancer..

Correction: MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer (2015)
Journal Article
Garofalo, M., Jeon, Y., Nuovo, G. J., Middleton, J., Secchiero, P., Joshi, P., …Croce, C. M. Correction: MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer. PloS one, 10(6), e0131729. https://doi.org/10.1371/journal.pone.0131729

After the publication of the article, it was noticed that fragments of text in this article overlap with that from previous publications. The overlap in the text relates to the Introduction, Results and Discussion sections, where sentences were repro... Read More about Correction: MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer.