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The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. (2024)
Journal Article
Parmar, S. S., Mohamed, M. O., Mamas, M. A., & Wilkie, R. (in press). The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. Expert Review of Cardiovascular Therapy, 22(1-3), 1-9. https://doi.org/10.1080/14779072.2024.2311696

The prevalence of osteoarthritis (OA) and cardiovascular disease are increasing and both conditions share similar risk factors. We investigated the association between OA and receipt of invasive managements and clinical outcomes in patients with acut... Read More about The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients..

European Society of Cardiology Quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation (2024)
Journal Article
Ali, N., Aktaa, S., Younsi, T., Beska, B., Batra, G., Blackman, D. J., …Gale, C. P. (in press). European Society of Cardiology Quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation. European Heart Journal - Quality of Care and Clinical Outcomes, Article qcae006. https://doi.org/10.1093/ehjqcco/qcae006

Aims To develop a suite of quality indicators (QIs) for the evaluation of the care and outcomes for adults undergoing transcatheter aortic valve implantation (TAVI). Methods and results We followed the European Society of Cardiology (ESC) method... Read More about European Society of Cardiology Quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation.

The invasive investigation of INOCA in the coronary catheterization lab (2024)
Journal Article
Burgess, S. N., & Mamas, M. A. (2024). The invasive investigation of INOCA in the coronary catheterization lab. American Heart Journal Plus: Cardiology Research and Practice, 38, Article 100365. https://doi.org/10.1016/j.ahjo.2024.100365

Over half of all patients with angina have no angiographically demonstratable obstructive coronary disease, with a significant proportion of these patients having undiagnosed microvascular dysfunction and/or vasospastic angina. In chronic coronary sy... Read More about The invasive investigation of INOCA in the coronary catheterization lab.

Complex High-risk Percutaneous Coronary Intervention Types, Trends, and Outcomes in Non-surgical Centres (2024)
Journal Article
Shamkhani, W., Rashid, M., Moledina, S., Ludman, P., Curzen, N., Wijeysundera, H. C., …Mamas, M. A. (2024). Complex High-risk Percutaneous Coronary Intervention Types, Trends, and Outcomes in Non-surgical Centres. Canadian Journal of Cardiology, https://doi.org/10.1016/j.cjca.2024.01.003

Background Limited data are available on complex, high-risk percutaneous coronary intervention (CHiP) trends and outcomes in non-surgical centres (NSC), particularly in healthcare systems where most centers are NSCs. Methods Using data from a na... Read More about Complex High-risk Percutaneous Coronary Intervention Types, Trends, and Outcomes in Non-surgical Centres.

Heart Failure Readmission in Patients With ST-Segment Elevation Myocardial Infarction and Active Cancer (2024)
Journal Article
Dafaalla, M., Abramov, D., Van Spall, H. G., Ghosh, A. K., Gale, C. P., Zaman, S., …Mamas, M. A. (in press). Heart Failure Readmission in Patients With ST-Segment Elevation Myocardial Infarction and Active Cancer. JACC: CardioOncology, 6(1), 117-129. https://doi.org/10.1016/j.jaccao.2023.10.011

Background Although numerous studies have examined readmission with heart failure (HF) after acute myocardial infarction (AMI), limited data are available on HF readmission in cancer patients post-AMI. Objectives This study aimed... Read More about Heart Failure Readmission in Patients With ST-Segment Elevation Myocardial Infarction and Active Cancer.

Clinical Outcomes of Percutaneous Coronary Intervention in Amyloidosis, Sarcoidosis, and Hemochromatosis (2023)
Journal Article
Hussain, B., Malik, H., Mamas, M. A., Desai, R., Aggarwal, V., Kumar, G., …Paul, T. K. (2023). Clinical Outcomes of Percutaneous Coronary Intervention in Amyloidosis, Sarcoidosis, and Hemochromatosis. Journal of the Society for Cardiovascular Angiography & Interventions, Article 101267. https://doi.org/10.1016/j.jscai.2023.101267

Background Infiltrative diseases (ID), including amyloidosis, sarcoidosis, and hemochromatosis comprise a wide spectrum of disorders characterized by abnormal cellular infiltration in multiple organs, including th... Read More about Clinical Outcomes of Percutaneous Coronary Intervention in Amyloidosis, Sarcoidosis, and Hemochromatosis.

Efficacy and safety of colchicine for the prevention of postoperative atrial fibrillation among patients undergoing major cardiothoracic surgery: a meta-analysis and meta-regression of randomized controlled trials. (2023)
Journal Article
Rivera, F. B., Cha, S. W., Aparece, J. P., Jariyatamkitti, S., & Mamas, M. (in press). Efficacy and safety of colchicine for the prevention of postoperative atrial fibrillation among patients undergoing major cardiothoracic surgery: a meta-analysis and meta-regression of randomized controlled trials. Journal of Cardiovascular Pharmacology, 83(3), 265-270. https://doi.org/10.1097/FJC.0000000000001533

The role of colchicine for the prevention of postoperative atrial fibrillation (POAF) following cardiothoracic surgery is not well-established. We aimed to evaluate its potential in preventing POAF using data from randomized controlled trials (RCTs).... Read More about Efficacy and safety of colchicine for the prevention of postoperative atrial fibrillation among patients undergoing major cardiothoracic surgery: a meta-analysis and meta-regression of randomized controlled trials..

Oral anticoagulant prescribing among patients with cancer and atrial fibrillation in England, 2009–2019 (2023)
Journal Article
Ajabnoor, A. M., Parisi, R., Zghebi, S. S., Ashcroft, D. M., Faivre‐Finn, C., Morris, C., …Kontopantelis, E. (in press). Oral anticoagulant prescribing among patients with cancer and atrial fibrillation in England, 2009–2019. Cancer, https://doi.org/10.1002/cncr.35152

Background Anticoagulation of patients with atrial fibrillation (AF) and cancer is challenging because of their high risk for stroke and bleeding. Little is known of the variations of oral anticoagulant (OAC) prescribing in patients with AF with and... Read More about Oral anticoagulant prescribing among patients with cancer and atrial fibrillation in England, 2009–2019.

Cost-effectiveness of intravascular ultrasound-guided percutaneous intervention in patients with acute coronary syndromes: A UK perspective (2023)
Journal Article
Sharp, A. S. P., Kinnaird, T., Curzen, N., Ayyub, R., Alfonso, J. E., Mamas, M. A., & Bavière, H. V. (in press). Cost-effectiveness of intravascular ultrasound-guided percutaneous intervention in patients with acute coronary syndromes: A UK perspective. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcad073

Background Use of intravascular ultrasound (IVUS) during percutaneous coronary intervention (PCI) is associated with improved clinical outcomes over angiography alone. Despite this, the adoption of IVUS in clinical practice remains low. Aims To... Read More about Cost-effectiveness of intravascular ultrasound-guided percutaneous intervention in patients with acute coronary syndromes: A UK perspective.

European Society of Cardiology Core Curriculum for Cardio-Oncology. (2023)
Journal Article
López-Fernández, T., Farmakis, D., Ameri, P., Asteggiano, R., de Azambuja, E., Aznar, M., …Rosano, G. M. C. (in press). European Society of Cardiology Core Curriculum for Cardio-Oncology. European Journal of Heart Failure, 10.1002/ejhf.3102. https://doi.org/10.1002/ejhf.3102

Cardio-oncology is a rapidly growing field of cardiovascular (CV) medicine that has resulted from the continuously increasing clinical demand for specialized CV evaluation, prevention and management of patients suffering or surviving from malignant d... Read More about European Society of Cardiology Core Curriculum for Cardio-Oncology..

COVID-19 vaccine-associated myocarditis: Analysis of the suspected cases reported to the EudraVigilance and a systematic review of the published literature. (2023)
Journal Article
Jaiswal, V., Mukherjee, D., Peng Ang, S., Kainth, T., Naz, S., Babu Shrestha, A., …Siller-Matula, J. M. (2023). COVID-19 vaccine-associated myocarditis: Analysis of the suspected cases reported to the EudraVigilance and a systematic review of the published literature. IJC Heart & Vasculature, 49, 101280. https://doi.org/10.1016/j.ijcha.2023.101280

Background Myocarditis secondary to Coronavirus Disease 2019 (COVID-19) vaccination has been reported in the literature. Objective This study aimed to characterize the reported cases of myocarditis after COVID-19 vaccination based on age, gender... Read More about COVID-19 vaccine-associated myocarditis: Analysis of the suspected cases reported to the EudraVigilance and a systematic review of the published literature..

Cardiovascular Health Metrics Differ Between Individuals With and Without Cancer. (2023)
Journal Article
Kobo, O., Abramov, D., Fiuza, M., Chew, N. W. S., Ng, C. H., Parwani, P., …Mamas, M. A. (in press). Cardiovascular Health Metrics Differ Between Individuals With and Without Cancer. Journal of the American Heart Association, 12(23), Article e030942. https://doi.org/10.1161/JAHA.123.030942

Although individuals with cancer experience high rates of cardiovascular morbidity, there are limited data on the potential differences in cardiovascular health (CVH) metrics between individuals with and without cancer. The National Health and Nutrit... Read More about Cardiovascular Health Metrics Differ Between Individuals With and Without Cancer..

Sex-specific lifetime risk of cardiovascular events: the European Prospective Investigation into Cancer-Norfolk prospective population cohort study. (2023)
Journal Article
Pana, T. A., Mamas, M. A., Wareham, N. J., Khaw, K., Dawson, D. K., & Myint, P. K. (in press). Sex-specific lifetime risk of cardiovascular events: the European Prospective Investigation into Cancer-Norfolk prospective population cohort study. European Journal of Preventive Cardiology, Article zwad283. https://doi.org/10.1093/eurjpc/zwad283

Better understanding of sex differences in cardiovascular disease (CVD) is essential in tailoring appropriate preventative strategies. Using a large population-based study with follow-up >25 years, we aimed to determine sex-specific lifetime risks of... Read More about Sex-specific lifetime risk of cardiovascular events: the European Prospective Investigation into Cancer-Norfolk prospective population cohort study..

Cardiovascular Risk in Patients with Hematological Malignancies: A Systematic Review and Meta-Analysis (2023)
Journal Article
Yong, J. H., Mai, A. S., Matetić, A., Elbadawi, A., Elgendy, I. Y., Lopez-Fernandez, T., & Mamas, M. A. (2024). Cardiovascular Risk in Patients with Hematological Malignancies: A Systematic Review and Meta-Analysis. The American Journal of Cardiology, 212, 80-102. https://doi.org/10.1016/j.amjcard.2023.11.039

Patients with haematological malignancies (HM) are at risk of future cardiovascular (CV) events. We therefore conducted a systematic review and meta-analysis to quantify their risk of future CV events. We searched Medline and Embase databases from in... Read More about Cardiovascular Risk in Patients with Hematological Malignancies: A Systematic Review and Meta-Analysis.

Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study (2023)
Journal Article
Marshall, M., Mason, K. J., Edwards, J. J., Mamas, M. A., Bailey, J., Heron, N., …Jordan, K. P. (2023). Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study. Rheumatology Advances in Practice, 8(1), Article rkad104. https://doi.org/10.1093/rap/rkad104

Objective Musculoskeletal pain is a common risk factor for co-morbid conditions and might increase the risk of poor outcomes. The objective was to determine whether patients with pre-existing musculoskeletal pain have an increased risk for mortality... Read More about Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study.

Optical Coherence Tomography Predictors of SIde Branch REstenosis after unprotected Left Main bifurcation angioplasty using double kissing crush technique (OP-SIBRE LM Study). (2023)
Journal Article
Gupta, A., Shrivastava, A., Chhikara, S., Mamas, M. A., Vijayvergiya, R., Swamy, A., …Singh, C. (in press). Optical Coherence Tomography Predictors of SIde Branch REstenosis after unprotected Left Main bifurcation angioplasty using double kissing crush technique (OP-SIBRE LM Study). Catheterization and Cardiovascular Interventions, 103(1), 51-60. https://doi.org/10.1002/ccd.30915

Among the two stent strategies, contemporary evidence favors double kissing crush technique (DKC) for complex unprotected distal left main bifurcation (UdLMB) lesions. However one of the major challenges to these lesions is side branch (SB) restenosi... Read More about Optical Coherence Tomography Predictors of SIde Branch REstenosis after unprotected Left Main bifurcation angioplasty using double kissing crush technique (OP-SIBRE LM Study)..

Trends in Cardiovascular Mortality Among Individuals with Alzheimer's Disease in the United States, 1999-2020 (2023)
Journal Article
Ranganathan, S., Abramov, D., Chew, N. W., Mallen, C., Marshall, M., Kobo, O., & Mamas, M. A. (2024). Trends in Cardiovascular Mortality Among Individuals with Alzheimer's Disease in the United States, 1999-2020. The American Journal of Cardiology, 211, Article 326-333. https://doi.org/10.1016/j.amjcard.2023.11.044

This study aimed to compare the trends in cardiovascular diseases (CVD)-related mortality in patients with Alzheimer's Disease (AD) and in the general population aged 65 and above. Data from the CDC WONDER Multiple Cause of Death da... Read More about Trends in Cardiovascular Mortality Among Individuals with Alzheimer's Disease in the United States, 1999-2020.

Intravascular imaging guided versus coronary angiography guided percutaneous coronary intervention: systematic review and meta-analysis (2023)
Journal Article
Khan, S. U., Agarwal, S., Arshad, H. B., Akbar, U. A., Mamas, M. A., Arora, S., …Shah, A. R. (in press). Intravascular imaging guided versus coronary angiography guided percutaneous coronary intervention: systematic review and meta-analysis. BMJ, 383, e077848. https://doi.org/10.1136/bmj-2023-077848

Objective: To assess the absolute treatment effects of intravascular imaging guided versus angiography guided percutaneous coronary intervention in patients with coronary artery disease, considering their baseline risk. Design: Systematic review and... Read More about Intravascular imaging guided versus coronary angiography guided percutaneous coronary intervention: systematic review and meta-analysis.