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Impact of the COVID-19 Pandemic on Diabetes-Related Cardiovascular Mortality in the United States. (2023)
Journal Article
Bashar, H., Kobo, O., Khunti, K., Sun, L. Y., Rutter, M. K., Chew, N. W. S., …Mamas, M. A. (in press). Impact of the COVID-19 Pandemic on Diabetes-Related Cardiovascular Mortality in the United States. Journal of the American Heart Association, 12(13), e028896. https://doi.org/10.1161/JAHA.122.028896

Background In the past few decades, diabetes-related cardiovascular mortality has been steadily declining. However, the impact of the COVID19 pandemic on this trend has not been previously defined. Methods and Results Diabetes-related cardiovascular... Read More about Impact of the COVID-19 Pandemic on Diabetes-Related Cardiovascular Mortality in the United States..

Impact of Neighborhood Social Deprivation on Health Care Costs Associated With TAVR. (2023)
Journal Article
Sidhu, H., Qiu, F., Manoragavan, R., Ko, D. T., Mamas, M. A., Sud, M., …Wijeysundera, H. C. (2023). Impact of Neighborhood Social Deprivation on Health Care Costs Associated With TAVR. Circulation: Cardiovascular Quality and Outcomes, 16(7), Article e009761. https://doi.org/10.1161/CIRCOUTCOMES.122.009761

Cumulative costs of transcatheter aortic valve replacement (TAVR) differ in the referral, procedural and postprocedural phases depending on patient comorbidities, type of procedure, and procedural complications. Our goal was to determine the associat... Read More about Impact of Neighborhood Social Deprivation on Health Care Costs Associated With TAVR..

Meta-Analysis on the Clinical Outcomes With Polypills for Cardiovascular Disease Prevention (2023)
Journal Article
Sedhom, R., Hamed, M., Tan, W., Mansoor, H., Stoletniy, L., Mamas, M., …Elbadawi, A. (in press). Meta-Analysis on the Clinical Outcomes With Polypills for Cardiovascular Disease Prevention. American Journal of Cardiology, 201, 211-218. https://doi.org/10.1016/j.amjcard.2023.06.001

Randomized controlled trials (RCTs) examining the outcomes of “polypill” therapy in cardiovascular disease prevention have yielded mixed results. We performed an electronic search through January 2023 for RCTs that examined the use... Read More about Meta-Analysis on the Clinical Outcomes With Polypills for Cardiovascular Disease Prevention.

In-hospital outcomes of acute ischaemic stroke patients with atrial septal defect. A national inpatient sample study. (2023)
Journal Article
Pana, T. A., Craigen, F., Mohamed, M. O., Mamas, M. A., & Myint, P. K. (in press). In-hospital outcomes of acute ischaemic stroke patients with atrial septal defect. A national inpatient sample study. American Journal of Cardiovascular Research, 13(3), 183-191

Atrial septal defects (ASD) are a well-recognised risk factor for acute ischaemic stroke (AIS). We aimed to delineate the relationship between ASD and in-hospital AIS outcomes (mortality, severe stroke (National Institutes of Health Stroke Scale (NIH... Read More about In-hospital outcomes of acute ischaemic stroke patients with atrial septal defect. A national inpatient sample study..

Regional variations in heart failure: a global perspective. (2023)
Journal Article
Yogeswaran, V., Hidano, D., Diaz, A. E., Van Spall, H. G. C., Mamas, M. A., Roth, G. A., & Cheng, R. K. (in press). Regional variations in heart failure: a global perspective. Heart, heartjnl-2022-321295. https://doi.org/10.1136/heartjnl-2022-321295

Heart failure (HF) is a global public health concern that affects millions of people worldwide. While there have been significant therapeutic advancements in HF over the last few decades, there remain major disparities in risk factors, treatment patt... Read More about Regional variations in heart failure: a global perspective..

Mortality across treatment strategies in intermediate-to-high risk pulmonary embolism in the modern era: A meta-analysis of observational studies and RCTs. (2023)
Journal Article
Iannaccone, M., Franchin, L., Russo, F., Botti, G., Castellano, D., Montorfano, M., …Chieffo, A. (2023). Mortality across treatment strategies in intermediate-to-high risk pulmonary embolism in the modern era: A meta-analysis of observational studies and RCTs. International Journal of Cardiology, 387, Article 131127. https://doi.org/10.1016/j.ijcard.2023.131127

Pulmonary embolism (PE) represents one of the leading causes of death worldwide and mainly treated with medical management, although the utility of more invasive approaches has emerged more recently. This meta-analysis aims to evaluate the 30-day mor... Read More about Mortality across treatment strategies in intermediate-to-high risk pulmonary embolism in the modern era: A meta-analysis of observational studies and RCTs..

Risk of Venous Thromboembolism With Gout Flares (2023)
Journal Article
Cipolletta, E., Tata, L. J., Nakafero, G., Avery, A. J., Mamas, M. A., & Abhishek, A. (2023). Risk of Venous Thromboembolism With Gout Flares. Arthritis and Rheumatology, 75(9), 1638-1647. https://doi.org/10.1002/art.42480

ObjectivePrevious studies demonstrated that the risk of venous thromboembolism (VTE) is increased in patients with gout, but not whether there was a temporal association between gout flare and VTE. This study was undertaken to evaluate potential temp... Read More about Risk of Venous Thromboembolism With Gout Flares.

Ethnic Disparities in ST-Segment Elevation Myocardial Infarction Outcomes and Processes of Care in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: A Nationwide Cohort Study (2023)
Journal Article
Weight, N., Moledina, S., Sun, L., Kragholm, K., Freeman, P., Diaz-Arocutipa, C., …Mamas, M. A. (in press). Ethnic Disparities in ST-Segment Elevation Myocardial Infarction Outcomes and Processes of Care in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: A Nationwide Cohort Study. Angiology, https://doi.org/10.1177/00033197231182555

Trials suggest patients with ST-elevation myocardial infarction (STEMI) without ‘standard modifiable cardiovascular risk factors’ (SMuRFs) have poorer outcomes, but the role of ethnicity has not been investigated. We analyzed 118,177 STEMI patients u... Read More about Ethnic Disparities in ST-Segment Elevation Myocardial Infarction Outcomes and Processes of Care in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: A Nationwide Cohort Study.

Effects of Valvular Heart Disease on Clinical Outcomes in Sarcoidosis. (2023)
Journal Article
Hussain, B., Markson, F., Mamas, M. A., Alraies, C., Aggarwal, V., Kumar, G., …Paul, T. K. (2023). Effects of Valvular Heart Disease on Clinical Outcomes in Sarcoidosis. Current Problems in Cardiology, 48(10), Article 101866. https://doi.org/10.1016/j.cpcardiol.2023.101866

Systemic sarcoidosis can lead to heart failure, conduction abnormalities and ventricular arrhythmias although data on concomitant valvular heart disease (VHD) is limited. We reported the prevalence and outcomes of VHD in systemic sarcoidosis. A retro... Read More about Effects of Valvular Heart Disease on Clinical Outcomes in Sarcoidosis..

Intravenous iron therapy among patients with heart failure and iron deficiency: An updated meta-analysis of randomized controlled trials. (2023)
Journal Article
Hamed, M., Elseidy, S. A., Ahmed, A., Thakker, R., Mansoor, H., Khalili, H., …Elbadawi, A. (2023). Intravenous iron therapy among patients with heart failure and iron deficiency: An updated meta-analysis of randomized controlled trials. Heliyon, 9(6), Article e17245. https://doi.org/10.1016/j.heliyon.2023.e17245

Background: Randomized clinical trials (RCTs) evaluating the role of intravenous (IV) iron administration in patients with heart failure (HF) and iron deficiency (ID) have yielded inconsistent results. Methods: Electronic search of MEDLINE, EMBASE... Read More about Intravenous iron therapy among patients with heart failure and iron deficiency: An updated meta-analysis of randomized controlled trials..

Trends and predictions of metabolic risk factors for acute myocardial infarction: findings from a multiethnic nationwide cohort. (2023)
Journal Article
Chew, N. W. S., Chong, B., Kuo, S. M., Jayabaskaran, J., Cai, M., Zheng, H., …Chan, M. Y. (2023). Trends and predictions of metabolic risk factors for acute myocardial infarction: findings from a multiethnic nationwide cohort. The Lancet Regional Health - Western Pacific, 37, Article 100803. https://doi.org/10.1016/j.lanwpc.2023.100803

Understanding the trajectories of metabolic risk factors for acute myocardial infarction (AMI) is necessary for healthcare policymaking. We estimated future projections of the incidence of metabolic diseases in a multi-ethnic population with AMI. The... Read More about Trends and predictions of metabolic risk factors for acute myocardial infarction: findings from a multiethnic nationwide cohort..

Intracoronary imaging in PCI for acute coronary syndrome: Insights from British Cardiovascular Intervention Society registry. (2023)
Journal Article
Zaman, M., Stevens, C., Ludman, P., Wijeysundera, H. C., Siudak, Z., Sharp, A. S. P., …Mamas, M. A. (2023). Intracoronary imaging in PCI for acute coronary syndrome: Insights from British Cardiovascular Intervention Society registry. Cardiovascular Revascularization Medicine, 56, 50-56. https://doi.org/10.1016/j.carrev.2023.05.020

While previous studies have demonstrated the superiority of ICI-guided PCI over an angiography-based approach, there are limited data on all-comer ACS patients. This study aimed to identify the characteristics and in-hospital outcomes of patients und... Read More about Intracoronary imaging in PCI for acute coronary syndrome: Insights from British Cardiovascular Intervention Society registry..

Developing prediction models to estimate the risk of two survival outcomes both occurring: A comparison of techniques (2023)
Journal Article
Pate, A., Sperrin, M., Riley, R. D., Sergeant, J. C., Van Staa, T., Peek, N., …Martin, G. P. (2023). Developing prediction models to estimate the risk of two survival outcomes both occurring: A comparison of techniques. Statistics in Medicine, 42(18), 3184-3207. https://doi.org/10.1002/sim.9771

Introduction This study considers the prediction of the time until two survival outcomes have both occurred. We compared a variety of analytical methods motivated by a typical clinical problem of multimorbidity prognosis. Methods We considered f... Read More about Developing prediction models to estimate the risk of two survival outcomes both occurring: A comparison of techniques.

Sex-based differences in risk factors for incident myocardial infarction and stroke in the UK Biobank (2023)
Journal Article
Remfry, E., Ardissino, M., McCracken, C., Szabo, L., Neubauer, S., Harvey, N. C., …Raisi-Estabragh, Z. (in press). Sex-based differences in risk factors for incident myocardial infarction and stroke in the UK Biobank. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcad029

Aim This study examined sex-based differences in associations of vascular risk factors with incident cardiovascular events in the UK Biobank. Methods Baseline participant demographic, clinical, laboratory, anthropometric, and imaging characteris... Read More about Sex-based differences in risk factors for incident myocardial infarction and stroke in the UK Biobank.

What do we mean by complex percutaneous coronary intervention? An assessment of agreement amongst interventional cardiologists for defining complexity (2023)
Journal Article
Rjoob, K., McGilligan, V., McAllister, R., Bond, R., Doolub, G., Leslie, S. J., …Peace, A. (2023). What do we mean by complex percutaneous coronary intervention? An assessment of agreement amongst interventional cardiologists for defining complexity. Catheterization and Cardiovascular Interventions, 102(1), 1-10. https://doi.org/10.1002/ccd.30684

Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis (2023)
Journal Article
Chong, B., Jayabaskaran, J., Ruban, J., Goh, R., Chin, Y. H., Kong, G., …Chew, N. W. (2023). Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis. Circulation: Cardiovascular Imaging, 16(5), https://doi.org/10.1161/circimaging.122.015159

Epicardial adipose tissue (EAT) has garnered attention as a prognostic and risk stratification factor for cardiovascular disease. This study, via meta-analyses, evaluates the associations between EAT and cardiovascular outcomes stratified across imag... Read More about Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis.

Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis (2023)
Journal Article
Muhyieddeen, A., Cheng, S., Mamas, M. A., Beasley, D., Weins, G. C., & Gulati, M. (2023). Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis. Current Problems in Cardiology, 48(9), Article 101798. https://doi.org/10.1016/j.cpcardiol.2023.101798

This study assessed the COVID-19 pan-demic's impact on racial disparities in acute myocar-dial infarction (AMI) management and outcomes. We reviewed AMI patient management and outcomes in the pandemic's initial nine months, comparing COVID-19 and non... Read More about Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis.

In-hospital Outcomes of Patients With and Without Previous Coronary Artery Bypass Graft Surgery Who Present With a Non-ST-Segment Elevation Myocardial Infarction (2023)
Journal Article
Dhaduk, N., Xia, Y., Feit, F., Mamas, M., Alviar, C., Keller, N., …Bangalore, S. (2023). In-hospital Outcomes of Patients With and Without Previous Coronary Artery Bypass Graft Surgery Who Present With a Non-ST-Segment Elevation Myocardial Infarction. American Journal of Cardiology, 194, 78-85. https://doi.org/10.1016/j.amjcard.2023.02.013

The clinical course of patients with a previous coronary artery bypass graft surgery (CABG) presenting with non-ST-elevation myocardial infarction (NSTEMI) is not well defined. We aimed to compare the management and outcomes of patients with and with... Read More about In-hospital Outcomes of Patients With and Without Previous Coronary Artery Bypass Graft Surgery Who Present With a Non-ST-Segment Elevation Myocardial Infarction.