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Establishing a peritoneal dialysis technique survival core outcome measure: A standardised outcomes in nephrology-peritoneal dialysis consensus workshop report (2024)
Journal Article
Elphick, E. H., Manera, K. E., Viecelli, A. K., Craig, J. C., Cho, Y., Ju, A., …Lambie, M. (in press). Establishing a peritoneal dialysis technique survival core outcome measure: A standardised outcomes in nephrology-peritoneal dialysis consensus workshop report. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241287684

Background Technique survival, also reported with negative connotations as technique failure or transfer from peritoneal dialysis to haemodialysis, has been identified by patients, caregivers and health professionals as a critically important outcome... Read More about Establishing a peritoneal dialysis technique survival core outcome measure: A standardised outcomes in nephrology-peritoneal dialysis consensus workshop report.

O24 ACUTE KIDNEY INJURY IN PREGNANCY AND CARDIO-RENAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS (2024)
Presentation / Conference
Jeyaraman, D., Peiris, T. D. P., Alahmdi, H., Fish, R., Lambie, M., & Wu, P. (2024, September). O24 ACUTE KIDNEY INJURY IN PREGNANCY AND CARDIO-RENAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Presented at 30th Congress of the International Society of Hypertension, Cartegena de Indias, Colombia

Background and Objective: Acute kidney injury (AKI) is a common problem in pregnancy but adverse cardio-renal outcomes following AKI in pregnancy has not been systematically evaluated. We aimed to quantify the risk of adverse cardio-renal outcomes of... Read More about O24 ACUTE KIDNEY INJURY IN PREGNANCY AND CARDIO-RENAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis. (2024)
Journal Article
Bonomini, M., Davies, S., Kleophas, W., Lambie, M., Reboldi, G., Liberato, L. D., …Arduini, A. (2024). Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241274106

Peritoneal dialysis adoption and technique survival is affected by limitations related to peritoneal membrane longevity and metabolic alterations. Indeed, almost all peritoneal dialysis fluids exploit glucose as an osmotic agent that rapidly diffuses... Read More about Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis..

P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review (2024)
Presentation / Conference
Dahanayake, C., Bajpai, R., Jordan, K. M., Lambie, M., & Roddy, E. (2024, April). P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims
Uric acid nephrolithiasis is a recognised side-effect of uricosuric therapies and a contraindication to their use. The objective of this systematic review was to assess the incidence and risk of nephrolithiasis in people with gout re... Read More about P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review.

International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS (2024)
Journal Article
Nitta, K., Bieber, B., Karaboyas, A., Johnson, D. W., Kanjanabuch, T., Kim, Y.-L., …Kawanishi, H. (2024). International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 14(3), https://doi.org/10.1177/08968608241235516

Background:
Mineral bone disorder (MBD) in chronic kidney disease (CKD) is associated with high symptom burden, fractures, vascular calcification, cardiovascular disease and increased morbidity and mortality. CKD-MBD studies have been limited in per... Read More about International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS.

Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis (2024)
Journal Article
Jeyaraman, D., Walters, B., Bramham, K., Fish, R., Lambie, M., & Wu, P. (2024). Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis. BJOG: An International Journal of Obstetrics and Gynaecology, https://doi.org/10.1111/1471-0528.17807

Background
Chronic kidney disease (CKD) is associated with an increased risk of adverse pregnancy outcomes, but the risk at different stages of CKD (defined by estimated glomerular filtration rate, eGFR) compared with women without CKD has not been... Read More about Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis.

Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England (2024)
Journal Article
Damery, S., Lambie, M., Williams, I., Coyle, D., Fotheringham, J., Solis-Trapala, I., …Davies, S. J. (2024). Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241232200

Background:
Disparities in home dialysis uptake across England suggest inequity and unexplained variation in access. We surveyed staff at all English kidney centres to identify patterns in service organisation/delivery and explore correlations with... Read More about Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England.

Gastric Acid Suppression Therapy and its Association with Peritoneal Dialysis-Associated Peritonitis in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) (2023)
Journal Article
Goldman, S., Zhao, J., Bieber, B., Pisoni, R. L., Horowitz, L., Nessim, S. J., …Perl, J. (2023). Gastric Acid Suppression Therapy and its Association with Peritoneal Dialysis-Associated Peritonitis in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS). Kidney360, 5(3), 370-379. https://doi.org/10.34067/kid.0000000000000325

Background
Peritonitis is a major peritoneal dialysis–related complication. We determined whether gastric acid suppression (GAS) (proton pump inhibitor [PPI] or histamine-2 receptor antagonists [H2RAs]) use was associated with all-cause and organis... Read More about Gastric Acid Suppression Therapy and its Association with Peritoneal Dialysis-Associated Peritonitis in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS).

International Variations in Serum PTH and Calcium Levels and Their Mortality Associations in Peritoneal Dialysis Patients: Results from PDOPPS: TH-PO161 (2023)
Presentation / Conference
Nitta, K., Bieber, B., Karaboyas, A., Johnson, D. W., Kanjanabuch, T., Kim, Y., …Kawanishi, H. (2023, November). International Variations in Serum PTH and Calcium Levels and Their Mortality Associations in Peritoneal Dialysis Patients: Results from PDOPPS: TH-PO161. Poster presented at Kidney Week, Philadelphia, PA

Robust Joint Models of Albumin and All-Cause Mortality in Incident Peritoneal Dialysis Patients: A Dynamic Predictions Perspective Adjusting for Competing Risks (2023)
Presentation / Conference
Damgov, I., Kieser, M., Rutherford, P., Lambie, M., Davies, S. J., Wong, M. G., …Schmitt, C. P. (2023, November). Robust Joint Models of Albumin and All-Cause Mortality in Incident Peritoneal Dialysis Patients: A Dynamic Predictions Perspective Adjusting for Competing Risks. Poster presented at ASN Kidney Week, Philadelphia, PA, USA

Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis (2023)
Journal Article
Istanbuly, O., Belcher, J., Tabinor, M., Solis-Trapala, I., Lambie, M., & Davies, S. J. (in press). Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis. BMC Nephrology, 24(1), Article 312. https://doi.org/10.1186/s12882-023-03370-4

Background: Systemic inflammation, measured as circulating Interleukin-6 (IL-6) levels, is associated with cardiovascular and all-cause mortality in chronic kidney disease. However, this has not been convincingly demonstrated in a systematic review o... Read More about Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis.

An update on absolute and relative indications for dialysis treatment modalities (2023)
Journal Article
Lambie, M., & Davies, S. (2023). An update on absolute and relative indications for dialysis treatment modalities. Clinical Kidney Journal, 16(Supplement_1), i39-i47. https://doi.org/10.1093/ckj/sfad062

Background Choosing a dialysis modality is an important decision for people to make as their kidney failure progresses. In doing so, their options should be informed by any absolute or relative indications that may favour one modality over another. M... Read More about An update on absolute and relative indications for dialysis treatment modalities.

Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: Results from a real-world clinical audit (2023)
Journal Article
Wijewickrama, P., Onyema, M., Eid, H., Phare, N., Dick, J., Moutzouris, D., …Karalliedde, J. (in press). Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: Results from a real-world clinical audit. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608231195492

There is limited data on the standards of diabetes care in people on peritoneal dialysis (PD). Our aim was to assess the standards of diabetes care and the burden of hypoglycaemia in people with diabetes on PD. We performed a retrospective study at t... Read More about Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: Results from a real-world clinical audit.

The Peritoneal Membrane and its Role in Peritoneal Dialysis. (2023)
Journal Article
Morelle, J., Lambie, M., Öberg, C. M., & Davies, S. (in press). The Peritoneal Membrane and its Role in Peritoneal Dialysis. Clinical Journal of the American Society of Nephrology, 10.2215/CJN.0000000000000282. https://doi.org/10.2215/CJN.0000000000000282

A healthy and functional peritoneal membrane is key to achieve sufficient ultrafiltration and to restore fluid balance, a major component of high-quality prescription in patients treated with peritoneal dialysis (PD). Variability in membrane function... Read More about The Peritoneal Membrane and its Role in Peritoneal Dialysis..

Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis (2023)
Journal Article
Wijewickrama, P., Williams, J., Bain, S., Dasgupta, I., Chowdhury, T. A., Wahba, M., …Karalliedde, J. (2023). Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis. Kidney International Reports, 8(4), 700-714. https://doi.org/10.1016/j.ekir.2023.01.040

There is an increasing number of people with diabetes on peritoneal dialysis (PD) worldwide. However, there is a lack of guidelines and clinical recommendations for managing glucose control in people with diabetes on PD. The aim of this review is to... Read More about Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis.

IMPROVE-PD Finder: A Web-Based Platform to Search and Share Peritoneal Dialysis Biobank, Registry, and Clinical Trial Metadata (2023)
Journal Article
Devuyst, O., Jakulj, L., Vervloet, M., Ruiz-Ortega, M., Rossignol, P., Rutherford, P., …Johnson, D. (2023). IMPROVE-PD Finder: A Web-Based Platform to Search and Share Peritoneal Dialysis Biobank, Registry, and Clinical Trial Metadata. Kidney International Reports, 8(4), 912-915. https://doi.org/10.1016/j.ekir.2023.01.003

Peritoneal dialysis (PD) is a life-sustaining kidney replacement therapy for the increasing number of people with permanent kidney failure across all age groups worldwide. Although PD potentially offers socioeconomic and performance benefits over hem... Read More about IMPROVE-PD Finder: A Web-Based Platform to Search and Share Peritoneal Dialysis Biobank, Registry, and Clinical Trial Metadata.