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All Outputs (3)

Isolation of genes controlling apoptosis through their effects on cell survival (2006)
Journal Article
Williams, G. T., Hughes, J. P., Stoneman, V., Anderson, C. L., McCarthy, N. J., Mourtada-Maarabouni, M., …Farzaneh, F. (2006). Isolation of genes controlling apoptosis through their effects on cell survival. Gene Therapy and Molecular Biology, 10(28), 255-262

The identification of the most suitable molecular targets for gene and drug therapy is the crucial first step in the development of new disease treatments. The rational identification of such targets depends on a detailed understanding of the patholo... Read More about Isolation of genes controlling apoptosis through their effects on cell survival.

The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: Research update (2006)
Journal Article
Maarabouni, M. M., & Williams, G. T. (2006). The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: Research update. Scientific World Journal, 1705 - 1712. https://doi.org/10.1100/tsw.2006.268

The candidate tumour-suppressor gene, LUCA-15/RBM5/H37, maps to the lung cancer tumour-suppressor locus 3p21.3. The LUCA-15 gene locus encodes at least four alternatively spliced transcripts that have been shown to function as regulators of apoptosis... Read More about The antiapoptotic RBM5/LUCA-15/H37 gene and its role in apoptosis and human cancer: Research update.

Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes (2006)
Journal Article
Mourtada-Maarabouni, M., Keen, J., Clark, J., Cooper, C. S., & Williams, G. T. (2006). Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes. Experimental Cell Research, 312(10), 1745-1752. https://doi.org/10.1016/j.yexcr.2006.02.009

RBM5 (RNA-binding motif protein 5/LUCA-15/H37) is encoded at the lung cancer tumor suppressor locus 3p21.3 and itself has several important characteristics of a tumor suppressor, including both potentiation of apoptosis and inhibition of the cell cyc... Read More about Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes.