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Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence (2024)
Journal Article
Gupta, A., & Maffulli, N. (2024). Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence. Pain and Therapy, 13(6), 1377-1386. https://doi.org/10.1007/s40122-024-00661-y

Introduction: Osteoarthritis (OA) of the knee affects millions of people with sizable socioeconomic burden. Conventional treatment modalities are prioritized, turning to surgical intervention only when they have failed. However, these traditional mod... Read More about Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence.

Bone-patellar tendon-bone, hamstring, and quadriceps tendon autografts for anterior cruciate ligament reconstruction in skeletally immature patients: a systematic review (2024)
Journal Article
Migliorini, F., Cocconi, F., Schäfer, L., Vaishya, R., Kämmer, D., & Maffulli, N. (2024). Bone-patellar tendon-bone, hamstring, and quadriceps tendon autografts for anterior cruciate ligament reconstruction in skeletally immature patients: a systematic review. British Medical Bulletin, 152(1), 16-27. https://doi.org/10.1093/bmb/ldae011

Introduction
Historically, anterior cruciate ligament (ACL) ruptures in the paediatric age group were managed conservatively with bracing, casting, activity modification, and physical therapy. However, most of these patients had to reduce their spor... Read More about Bone-patellar tendon-bone, hamstring, and quadriceps tendon autografts for anterior cruciate ligament reconstruction in skeletally immature patients: a systematic review.

Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review (2024)
Journal Article
Migliorini, F., Maffulli, N., Memminger, M. K., Simeone, F., Rath, B., & Huber, T. (in press). Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review. Archives of Orthopaedic and Trauma Surgery, https://doi.org/10.1007/s00402-024-05579-w

Introduction
In orthopaedic research, it is crucial to determine changes that are statistically significant and clinically meaningful. One approach to accomplish this is by calculating the Minimal Clinically Important Difference (MCID), the Clinical... Read More about Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review.

Sacroiliac joint pain: what treatment and when. (2024)
Journal Article
Cocconi, F., Maffulli, N., Bell, A., Memminger, M. K., Simeone, F., & Migliorini, F. (in press). Sacroiliac joint pain: what treatment and when. Expert Review of Neurotherapeutics, 1-8. https://doi.org/10.1080/14737175.2024.2400682

Spinal and non-spinal pathologies can cause low back pain. Non-spinal sources of low back pain include the sacroiliac joint (SIJ) and the hip. SIJ pain can be treated either conservatively or surgically. Current strategies for managing sacroiliac joi... Read More about Sacroiliac joint pain: what treatment and when..

Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis (2024)
Journal Article
Migliorini, F., Betsch, M., Maffulli, N., Schäfer, L., Hildebrand, F., Kubach, J., & Pasurka, M. (in press). Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis. Scientific Reports, 14(1), Article 21162. https://doi.org/10.1038/s41598-024-71326-1

The present Bayesian network meta-analysis compared different types of polyethylene liners in total hip arthroplasty (THA) in terms of wear penetration (mm/year) and rate of revision. The type of liners compared were the crosslinked ultra-high molecu... Read More about Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis.

Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review (2024)
Journal Article
Lucenti, L., Maffulli, N., Bardazzi, T., Saggini, R., Memminger, M., Simeone, F., & Migliorini, F. (in press). Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review. Journal of Clinical Medicine, 13(17), https://doi.org/10.3390/jcm13175219

Background: Femoroacetabular impingement (FAI) is common. The present systematic review updates the current evidence on return to sport (RTS) in patients who have undergone arthroscopic surgery for FAI in any of its variants (CAM, pincer, or both). M... Read More about Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review.

Pharmacological management of secondary chronic spinal cord injury: a systematic review (2024)
Journal Article
Migliorini, F., Cocconi, F., Schäfer, L., Simeone, F., Jeyaraman, M., & Maffulli, N. (2024). Pharmacological management of secondary chronic spinal cord injury: a systematic review. British Medical Bulletin, 151(1), 49–68. https://doi.org/10.1093/bmb/ldae009

Introduction Spinal cord injury (SCI) may bring lifelong consequences for affected patients and a high financial burden to the health care system. Source of data Published peer-reviewed scientific articles identified from EMBASE, Google Scholar, PubM... Read More about Pharmacological management of secondary chronic spinal cord injury: a systematic review.

Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study (2024)
Journal Article
Kashte, S. B., Kadam, S., Maffulli, N., Potty, A. G., Migliorini, F., & Gupta, A. (2024). Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study. Journal of Orthopaedic Surgery and Research, 19(1), 1-11. https://doi.org/10.1186/s13018-024-05028-9

Background
Bone defects, especially critical-size bone defects, and their repair pose a treatment challenge. Osteoinductive scaffolds have gained importance given their potential in bone tissue engineering applications.

Methods
Polycaprolactone... Read More about Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study.

Anodal tDCS improves the effect of neuromuscular training on the feedforward activity of lower extremity muscles in female taekwondo athletes with dynamic knee valgus (2024)
Journal Article
Moshashaei, M. S., Gandomi, F., Amiri, E., & Maffulli, N. (in press). Anodal tDCS improves the effect of neuromuscular training on the feedforward activity of lower extremity muscles in female taekwondo athletes with dynamic knee valgus. Scientific Reports, 14(1), Article 20007. https://doi.org/10.1038/s41598-024-70328-3

Transcranial direct current stimulation (tDCS) can increase cortical excitability of a targeted brain area. This study aimed to investigate the effect of adding anodal-tDCS (a-tDCS) to neuromuscular training (NMT) on the dynamic knee valgus (DKV) and... Read More about Anodal tDCS improves the effect of neuromuscular training on the feedforward activity of lower extremity muscles in female taekwondo athletes with dynamic knee valgus.

Beyond pixel: Superpixel-based MRI segmentation through traditional machine learning and graph convolutional network (2024)
Journal Article
Khatun, Z., Jónsson, H., Tsirilaki, M., Maffulli, N., Oliva, F., Daval, P., Tortorella, F., & Gargiulo, P. (2024). Beyond pixel: Superpixel-based MRI segmentation through traditional machine learning and graph convolutional network. Computer Methods and Programs in Biomedicine, 256, Article 108398. https://doi.org/10.1016/j.cmpb.2024.108398

Background and Objective:
Tendon segmentation is crucial for studying tendon-related pathologies like tendinopathy, tendinosis, etc. This step further enables detailed analysis of specific tendon regions using automated or semi-automated methods. Th... Read More about Beyond pixel: Superpixel-based MRI segmentation through traditional machine learning and graph convolutional network.

Shoulder balloon spacer for massive irreparable rotator cuff tears results in significant improvements (2024)
Journal Article
Savarese, E., Aicale, R., Romeo, R., & Maffulli, N. (in press). Shoulder balloon spacer for massive irreparable rotator cuff tears results in significant improvements. Knee Surgery, Sports Traumatology, Arthroscopy, https://doi.org/10.1002/ksa.12445

AbstractPurposeThe aim of the present study was to assess the effectiveness of balloon implantation in patients with irreparable supraspinatus tears alone or in combination with other rotator cuff (RC) tendon tears and the effect of several covariabl... Read More about Shoulder balloon spacer for massive irreparable rotator cuff tears results in significant improvements.

TRANSCULTURAL ADAPTATION AND VALIDATION OF THE 4-DOMAIN SPORTS PROM INTO ITALIAN. (2024)
Journal Article
Piedade, S. R., Canata, G. L., & Maffulli, N. (2024). TRANSCULTURAL ADAPTATION AND VALIDATION OF THE 4-DOMAIN SPORTS PROM INTO ITALIAN. Journal of ISAKOS, https://doi.org/10.1016/j.jisako.2024.100305

This work aims to evaluate and validate the process of cross-cultural adaptation and validation of the 4-Domain Sports PROM (4-DSP) into Italian, assessing its understandability and reproducibility in all questionnaire domains for Italian-speaking pa... Read More about TRANSCULTURAL ADAPTATION AND VALIDATION OF THE 4-DOMAIN SPORTS PROM INTO ITALIAN..

Concurrent validity between self-reported International Physical Activity Questionnaire Short Form and Fibion accelerometer data among young adults in the UAE (2024)
Journal Article
Arumugam, A., Alsaafin, N., Shalash, R. J., Qadah, R. M., Al-Sharman, A., Moustafa, I. M., Shousha, T. M., Kumaran, S. D., Migliorini, F., & Maffulli, N. (in press). Concurrent validity between self-reported International Physical Activity Questionnaire Short Form and Fibion accelerometer data among young adults in the UAE. European Journal of Medical Research, 29(1), Article 426. https://doi.org/10.1186/s40001-024-01975-5

Self-reported physical activity questionnaires (e.g., International Physical Activity Questionnaire, IPAQ) are a cost-effective, time-saving, and accessible method to assess sedentary behaviour and physical activity. There are conflicting findings re... Read More about Concurrent validity between self-reported International Physical Activity Questionnaire Short Form and Fibion accelerometer data among young adults in the UAE.

Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Murugan, S., Ramasubramanian, S., Balaji, S., Maffulli, N., & Jeyaraman, M. (in press). Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review. Journal of Clinical Medicine, 13(16), Article 4794. https://doi.org/10.3390/jcm13164794

Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still n... Read More about Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review.

Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis. (2024)
Journal Article
Migliorini, F., Maffulli, N., Velaj, E., Bell, A., Kämmer, D., Eschweiler, J., & Hofmann, U. K. (in press). Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis. European Journal of Orthopaedic Surgery and Traumatology, https://doi.org/10.1007/s00590-024-04071-w

Venous thromboembolism (VTE) is a major concern following total knee arthroplasty (TKA). The optimal pharmacological prophylaxis remains, however, controversial. The present investigation compared several non-vitamin K antagonist oral anticoagulants... Read More about Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis..

Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers. (2024)
Journal Article
Rydzik, Ł., Kopańska, M., Wąsacz, W., Ouergui, I., Obmiński, Z., Pałka, T., Ambroży, T., Malliaropoulos, N., Maffulli, N., Lota, K. S., Jaszczur-Nowicki, J., Król, P., Czarny, W., & Szczygielski, J. (in press). Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers. Sports Medicine, https://doi.org/10.1007/s40279-024-02082-5

Kickboxing is a popular striking combat sport, and K-1 is a type of kickboxing. Direct head blows can cause significant long-term injury and affect brain wave activity. We aim to compare the changes in brain wave activities of fighters during a K-1 k... Read More about Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers..

Angioembolization in the management of joint pain: current concepts. (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Ramkumar, V., Ramasubramanian, S., Patro, B. P., Maffulli, N., & Jeyaraman, M. (in press). Angioembolization in the management of joint pain: current concepts. Die Orthopädie, https://doi.org/10.1007/s00132-024-04531-5

Joint pain is a common complaint owing to its origin in inflammatory and degenerative joint diseases. Recent research has helped narrow down inadequate angiogenesis as one of the causes. Angioembolization has emerged as a treatment option for this co... Read More about Angioembolization in the management of joint pain: current concepts..

Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography (2024)
Journal Article
Migliorini, F., Eschweiler, J., Betsch, M., Maffulli, N., Tingart, M., Hildebrand, F., Lecouturier, S., Rath, B., & Schenker, H. (2024). Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography. Journal of Orthopaedic Surgery and Research, 19(1), 1-8. https://doi.org/10.1186/s13018-024-04918-2

Background
This study evaluated the osseointegration potential of functionalised high-performance oxide ceramics (HPOC) in isolation or coated with BMP-2 or RGD peptides in 36 New Zeeland female rabbits using micro-computed tomography (micro CT). Th... Read More about Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography.