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Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials (2024)
Journal Article
Crocker, T. F., Jordão, M., Lam, N., Ramiz, R., Mirza, L., Patel, I., …Walford, R. (2024). Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials. Age and ageing, 53(5), 1-13. https://doi.org/10.1093/ageing/afae102

Introduction Community-based services to sustain independence for older people have varying configurations. A typology of these interventions would improve service provision and research by providing conceptual clarity and enabling the identification... Read More about Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials.

Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review] (2024)
Journal Article
Twohig, H., Bajpai, R., Corp, N., Faux-Nightingale, A., Mallen, C., Robinson, T., …Burton, C. (2024). Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review]. NIHR Open Research, 4(22), https://doi.org/10.3310/nihropenres.13549.1

Background Children and young people (CYP) may experience prolonged symptoms following COVID-19, commonly termed ‘Long-COVID’. The characteristics of Long-COVID in CYP are unclear, as are the sequalae of acute COVID-19. We aimed to systematically sy... Read More about Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review].

Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study (2024)
Journal Article
Bajpai, R., Partington, R., Muller, S., Forrester, H., Mallen, C. D., Clarson, L., …Roddy, E. (2024). Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study. Rheumatology, Article keae229. https://doi.org/10.1093/rheumatology/keae229

Objectives Colchicine is commonly used to prevent flares when starting urate-lowering therapy for gout. Patients with gout are frequently concurrently prescribed other medications (such as statins) that may interact with colchicine, increasing the r... Read More about Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study.

Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England (2024)
Journal Article
Lawton, S., Mallen, C., Hussain, Z., Bajpai, R., Muller, S., Holmstrom, C., …Helliwell, T. (2024). Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England. BMJ Open, 14(4), Article e083816. https://doi.org/10.1136/bmjopen-2023-083816

ObjectivesTo determine General Practice (GP) recording of carer status and the number of patients self-identifying as carers, while self-completing an automated check-in screen prior to a GP consultation.DesignA descriptive cross-sectional study.Sett... Read More about Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England.

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. (2024)
Journal Article
Muller, S., Bailey, J., Bajpai, R., Helliwell, T., Harrisson, S. A., Whittle, R., …Ashworth, J. (in press). Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. PAIN, https://doi.org/10.1097/j.pain.0000000000003239

Growing evidence from pharmacovigilance data and postmortem toxicology reports highlights the misuse potential of gabapentinoids. This study aimed to investigate the risk of serious adverse outcomes (drug misuse, overdose, major trauma), and their ri... Read More about Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study..

Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study (2024)
Journal Article
Chufal, K., Ahmad, I., Prakash, A., Miller, A., Umesh, P., Koul, V., …Gairola, M. (in press). Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study. Cardio-Oncology, 10(1), Article 21. https://doi.org/10.1186/s40959-024-00225-1

Objectives To investigate the association between radiotherapy (RT) and cardiac biomarkers in women with left-sided breast cancer. Methods This prospective observational study recruited patients with stage I-III left-sided breast cancer without... Read More about Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study.

Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise (2024)
Journal Article
Ahmad, I., Chufal, K. S., Miller, A. A., Bajpai, R., Umesh, P., Dawer, A., …Gairola, M. (in press). Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise. British Journal of Radiology, 97(1157), 913-919. https://doi.org/10.1093/bjr/tqae068

Oligometastatic Non-Small Cell Lung cancer (OMD NSCLC) has been proposed to bridge the spectrum between non-metastatic to widely metastatic states and is perceived as an opportunity for potential cure if removed. Twelve clinical trials on local treat... Read More about Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise.

Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis (2024)
Journal Article
Crocker, T. F., Ensor, J., Lam, N., Jordão, M., Bajpai, R., Bond, M., …Clegg, A. (2024). Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis. BMJ, 384, Article e077764. https://doi.org/10.1136/bmj-2023-077764

To synthesise evidence of the effectiveness of community based complex interventions, grouped according to their intervention components, to sustain independence for older people. Systematic review and network meta-analysis. Medline, Embase, CINAHL,... Read More about Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.

Effects of participatory ‘A’rt-Based Activity On ‘Health’ of Older Community-Dwellers: results from a randomized control trial of the Singapore A-Health Intervention (2023)
Journal Article
Ho, A. H. Y., Ma, S. H. X., Tan, M. K. B., Bajpai, R., Goh, S. S. N., Yeo, G., …Beauchet, O. (in press). Effects of participatory ‘A’rt-Based Activity On ‘Health’ of Older Community-Dwellers: results from a randomized control trial of the Singapore A-Health Intervention. Frontiers in Medicine, 10, Article 1238562. https://doi.org/10.3389/fmed.2023.1238562

Introduction: The practice of participatory art has been found to support the promotion, prevention, and management of health across the lifespan. However, clinical trials investigating the benefits of creative activities curated with and conducted i... Read More about Effects of participatory ‘A’rt-Based Activity On ‘Health’ of Older Community-Dwellers: results from a randomized control trial of the Singapore A-Health Intervention.

Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis (2023)
Journal Article
Shivakumar, M., Welsh, V., Bajpai, R., Helliwell, T., Mallen, C., Robinson, M., & Shepherd, T. (2024). Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis. Rheumatology International, 44, 235–247. https://doi.org/10.1007/s00296-023-05500-5

Agricultural workers constitute two-thirds of the population of Low- and Middle-Income Countries (LMIC) and are at increased risk of developing musculoskeletal disorders (MSD) due to high-risk activities. This systematic review and meta-analysis aim... Read More about Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis.

Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink (2023)
Journal Article
Roddy, E., Bajpai, R., Forrester, H., James Partington, R., D Mallen, C., Clarson, L. E., …Muller, S. (2023). Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, ard-2023-224154. https://doi.org/10.1136/ard-2023-224154

Objectives: To determine the risk of adverse events associated with colchicine or non-steroidal anti-inflammatory drug (NSAID) prophylaxis when initiating allopurinol for gout. Methods: We conducted two matched retrospective cohort studies in... Read More about Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink.

The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol (2023)
Journal Article
Cox, N., Hawarden, A., Bajpai, R., Farooq, S., Twohig, H., Muller, S., & Scott, I. C. (2024). The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol. Rheumatology International, 44, 435–440. https://doi.org/10.1007/s00296-023-05450-y

Pain is a major challenge for patients with inflammatory arthritis (IA). Depression and anxiety are common comorbidities in IA, associating with worse outcomes. How they relate to pain is uncertain, with existing systematic reviews (a) mainly conside... Read More about The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol.

Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials. (2023)
Journal Article
Sathish, T., Khunti, K., Narayan, K. M. V., Mohan, V., Davies, M. J., Yates, T., …Shaw, J. E. (in press). Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials. Diabetes Care, 46(11), 1903–1907. https://doi.org/10.2337/dc23-0696

To examine whether the effect of conventional lifestyle interventions on type 2 diabetes incidence differs by glucose-defined prediabetes phenotype. We searched multiple databases until 1 April 2023 for randomized controlled trials that recruited peo... Read More about Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials..

Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study. (2023)
Journal Article
Welsh, V. K., Mason, K. J., Bailey, J., Bajpai, R., Jordan, K. P., Mallen, C. D., & Burton, C. (2023). Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study. British Journal of General Practice (BJGP), 73(736), BJGP.2022.0648. https://doi.org/10.3399/bjgp.2022.0648

Background Rheumatic and musculoskeletal diseases (RMDs) are common and generally managed in primary care through supported self-care, physiotherapy, analgesia, and specialist referral where indicated. The COVID-19 pandemic led to abrupt changes in... Read More about Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study..

The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study (2023)
Journal Article
Burton, C., Mallen, C., Mason, K., Jordan, K., Welsh, V., Bajpai, R., & Bailey, J. (2023). The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study. Rheumatology Advances in Practice, 7(2), Article ARTN rkad044. https://doi.org/10.1093/rap/rkad044

Objectives To describe the impact of the COVID-19 pandemic upon referral patterns and incident diagnosis of inflammatory rheumatic and musculoskeletal diseases (iRMDs). Methods UK primary care data was used to describe referral patterns for pat... Read More about The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study.

Systematic review finds "spin"practices and poor reporting standards in studies on machine learning-based prediction models (2023)
Journal Article
Navarro, C. L. A., Damen, J. A. A., Takada, T., Nijman, S. W. J., Dhiman, P., Ma, J., …Hooft, L. (2023). Systematic review finds "spin"practices and poor reporting standards in studies on machine learning-based prediction models. Journal of Clinical Epidemiology, 158, 99-110. https://doi.org/10.1016/j.jclinepi.2023.03.024

OBJECTIVE: We evaluated the presence and frequency of spin practices and poor reporting standards in studies that developed and/or validated clinical prediction models using supervised machine learning techniques. STUDY DESIGN AND SETTING: We sys... Read More about Systematic review finds "spin"practices and poor reporting standards in studies on machine learning-based prediction models.

Expression of Angiopoetin-Like Protein-4 and Kidney Injury Molecule-1 as Preliminary Diagnostic Markers for Diabetes-Related Kidney Disease: A Single Center-Based Cross-Sectional Study (2023)
Journal Article
Bano, G., Imam, M. T., Bajpai, R., Alem, G., Kashyap, V. K., Habib, A., & Najmi, A. K. (2023). Expression of Angiopoetin-Like Protein-4 and Kidney Injury Molecule-1 as Preliminary Diagnostic Markers for Diabetes-Related Kidney Disease: A Single Center-Based Cross-Sectional Study. Journal of Personalized Medicine, 13(4), Article ARTN 577. https://doi.org/10.3390/jpm13040577

The purpose of the study was to examine the urinary levels of kidney injury molecule-1 (KIM-1) and angiopoietin-like protein-4 (ANGPTL-4) in individuals with diabetic kidney disease (DKD) and their association with established DKD diagnostic markers... Read More about Expression of Angiopoetin-Like Protein-4 and Kidney Injury Molecule-1 as Preliminary Diagnostic Markers for Diabetes-Related Kidney Disease: A Single Center-Based Cross-Sectional Study.

Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study (2023)
Journal Article
Ashworth, J., Bajpai, R., Muller, S., Bailey, J., Helliwell, T., Harrisson, S., …Mallen, C. (2023). Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study. The Lancet Regional Health Europe, 27, Article ARTN 100579. https://doi.org/10.1016/j.lanepe.2022.100579

Background The UK government reclassified gabapentin and pregabalin as ‘controlled drugs’ from April 2019. This study aimed to describe the trends in gabapentinoid prescribing before and immediately after reclassification, in the UK Clinical Practic... Read More about Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study.