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All Outputs (911)

History and Prospects for the Sustainability and Circularity of the Windowpane Oyster Placuna placenta Fishery in the Philippines (2023)
Journal Article
Rustia, J. M., Antonino, J. P., Velasco, R. R., Lima, M. A., Yates, E. A., & Fernig, D. G. (in press). History and Prospects for the Sustainability and Circularity of the Windowpane Oyster Placuna placenta Fishery in the Philippines. Fishes, 8(10), Article 493. https://doi.org/10.3390/fishes8100493

The windowpane oyster Placuna placenta lives in brackish coastal waters and has long been economically important to the Philippines because of its durable and translucent shell, which is used as a glass substitute and material for making windowpanes... Read More about History and Prospects for the Sustainability and Circularity of the Windowpane Oyster Placuna placenta Fishery in the Philippines.

Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects that Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells (2023)
Journal Article
Pagani, I., Ottoboni, L., Panina-Bordignon, P., Martino, G., Poli, G., Taylor, S., …Vicenzi, E. (in press). Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects that Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells. Pharmaceuticals, 16(10), Article 1385. https://doi.org/10.3390/ph16101385

Zika virus (ZIKV) infection during pregnancy can result in severe birth defects, such as microcephaly, as well as a range of other related health complications. Heparin, a clinical-grade anticoagulant, is shown to protect neural progenitor cells from... Read More about Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects that Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells.

Enhancing Neural Stem Cell Stimulation with Structured Piezoelectric Composites: An In Vitro Study (2023)
Journal Article
Jarkov, V., Waqar, I., Penev, A., Bowen, C., Adams, C., & Khanbareh, H. (in press). Enhancing Neural Stem Cell Stimulation with Structured Piezoelectric Composites: An In Vitro Study. Advanced engineering materials, 25(23), Article 2300696. https://doi.org/10.1002/adem.202300696

Spinal cord injuries can cause permanent tissue damage with debilitating and lasting effects on patients. Electrical stimulation has been established as an effective approach for promoting neural regeneration. However, the clinical applicability of t... Read More about Enhancing Neural Stem Cell Stimulation with Structured Piezoelectric Composites: An In Vitro Study.

Characterization of the swarming behavior of Anopheles coluzzii and Anopheles gambiae (Diptera: Culicidae) populations in a hybrid zone of Senegal. (2023)
Journal Article
Gueye, O. K., Niang, A., Faye, M. B., Dia, A. K., Ahmed, A. A., Sy, O., …Niang, E. H. A. (in press). Characterization of the swarming behavior of Anopheles coluzzii and Anopheles gambiae (Diptera: Culicidae) populations in a hybrid zone of Senegal. Journal of Medical Entomology, 60(6), 1278–1287. https://doi.org/10.1093/jme/tjad120

Anopheles gambiae and Anopheles coluzzii, often found in sympatry and synchronous, have undergone a premating reproductive isolation across their distribution range. However, in the Western coast of Africa, unexpected hybridization zones have been ob... Read More about Characterization of the swarming behavior of Anopheles coluzzii and Anopheles gambiae (Diptera: Culicidae) populations in a hybrid zone of Senegal..

Bangladesh's 2023 Dengue outbreak – age/gender-related disparity in morbidity and mortality and geographic variability of epidemic burdens (2023)
Journal Article
Haider, N., Asaduzzaman, M., Hassan, M. N., Rahman, M., Sharif, A. R., Ashrafi, S. A. A., …Zumla, A. (2023). Bangladesh's 2023 Dengue outbreak – age/gender-related disparity in morbidity and mortality and geographic variability of epidemic burdens. International Journal of Infectious Diseases, 136, 1-4. https://doi.org/10.1016/j.ijid.2023.08.026

Bangladesh is currently grappling to control its most devastating dengue fever outbreak recorded since the dengue virus (DENV) reappeared in the country in 2000 [1], [2], [3]. Although dengue is endemic in Bangladesh, the current dengue surge is unus... Read More about Bangladesh's 2023 Dengue outbreak – age/gender-related disparity in morbidity and mortality and geographic variability of epidemic burdens.

Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors † (2023)
Journal Article
Dolan, J., Ahmadipour, S., Wahart, A., Ni Cheallaigh, A., Sari, S., Eurtivong,, C., …Miller, G. (2023). Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors †. RSC Chemical Biology, 4(11), 865-870. https://doi.org/10.1039/D3CB00126A

Upon undergoing mucoid conversion within the lungs of cystic fibrosis patients, the pathogenic bacterium Pseudomonas aeruginosa synthesises copious quantities of the virulence factor and exopolysaccharide alginate. The enzyme guanosine diphosphate ma... Read More about Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors †.

Global prioritization of endemic zoonotic diseases for conducting surveillance in domestic animals to protect public health (2023)
Journal Article
Qiu, Y., Guitian, J., Webster, J. P. P., Musallam, I., Haider, N., Drewe, J. A. A., & Song, J. (2023). Global prioritization of endemic zoonotic diseases for conducting surveillance in domestic animals to protect public health. Philosophical Transactions B: Biological Sciences, 378(1887), Article ARTN 20220407. https://doi.org/10.1098/rstb.2022.0407

Zoonotic diseases (zoonoses) originating from domestic animals pose a significant risk to people's health and livelihoods, in addition to jeopardizing animal health and production. Effective surveillance of endemic zoonoses at the animal level is cru... Read More about Global prioritization of endemic zoonotic diseases for conducting surveillance in domestic animals to protect public health.

Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome. (2023)
Journal Article
Page, N., Taxiarchi, C., Tonge, D., Kuburic, J., Chesters, E., Kriezis, A., …Galizi, R. (in press). Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome. Communications Biology, 6, Article 850. https://doi.org/10.1038/s42003-023-05224-z

Understanding development and genetic regulation in the Anopheles gambiae germline is essential to engineer effective genetic control strategies targeting this malaria mosquito vector. These include targeting the germline to induce sterility or using... Read More about Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome..

Cysteamine-mediated blockade of the glycine cleavage system modulates epithelial cell inflammatory and innate immune responses to viral infection (2023)
Journal Article
Fraser-Pitt, D., Mercer, D. K., Francis, M., Toledo-Aparicio, D., Smith, D. W., & O'Neil, D. A. (2023). Cysteamine-mediated blockade of the glycine cleavage system modulates epithelial cell inflammatory and innate immune responses to viral infection. Biochemical and Biophysical Research Communications, 677, 168-181. https://doi.org/10.1016/j.bbrc.2023.08.021

Transient blockade of glycine decarboxylase (GLDC) can restrict de novo pyrimidine synthesis, which is a well-described strategy for enhancing the host interferon response to viral infection and a target pathway for some licenced anti-inflammatory th... Read More about Cysteamine-mediated blockade of the glycine cleavage system modulates epithelial cell inflammatory and innate immune responses to viral infection.

Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome (2023)
Journal Article
Page, N., Taxiarchi, C., Tonge, D., Kuburic, J., Chesters, E., Kriezis, A., …Galizi, R. (2023). Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome. Communications Biology, 6(1), Article 850. https://doi.org/10.1038/s42003-023-05224-z

Understanding development and genetic regulation in the Anopheles gambiae germline is essential to engineer effective genetic control strategies targeting this malaria mosquito vector. These include targeting the germline to induce sterility or using... Read More about Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome.

Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome (2023)
Journal Article
Hegde, S., Rauch, H. E., Hughes, G. L., & Shariat, N. (in press). Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome. Access Microbiology, 5(8), https://doi.org/10.1099/acmi.0.000599.v3

The microbiome profoundly influences many traits in medically relevant vectors such as mosquitoes, and a greater functional understanding of host-microbe interactions may be exploited for novel microbial-based approaches to control mosquito-borne dis... Read More about Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome.

Identification and characterization of two CRISPR/Cas systems associated with the mosquito microbiome (2023)
Journal Article
Hegde, S., Rauch, H. E., Hughes, G. L., & Shariat, N. (2023). Identification and characterization of two CRISPR/Cas systems associated with the mosquito microbiome. Access Microbiology, 5(8), https://doi.org/10.1099/acmi.0.000599.v4

The microbiome profoundly influences many traits in medically relevant vectors such as mosquitoes, and a greater functional understanding of host–microbe interactions may be exploited for novel microbial-based approaches to control mosquito-borne dis... Read More about Identification and characterization of two CRISPR/Cas systems associated with the mosquito microbiome.

Factors influencing oviposition behaviour of the invasive pest, Drosophila suzukii, derived from interactions with other Drosophila species: potential applications for control (2023)
Journal Article
Tungadi, T. D., Powell, G., Shaw, B., & Fountain, M. T. (2023). Factors influencing oviposition behaviour of the invasive pest, Drosophila suzukii, derived from interactions with other Drosophila species: potential applications for control. Pest Management Science, 79(11), 4132-4139. https://doi.org/10.1002/ps.7693

Drosophila suzukii (Matsumura) or spotted wing Drosophila is a worldwide invasive pest of soft‐ and stone‐fruit production. Female D. suzukii lay their eggs in ripening fruit and the hatched larvae damage fruit from the inside, rendering it unmarketa... Read More about Factors influencing oviposition behaviour of the invasive pest, Drosophila suzukii, derived from interactions with other Drosophila species: potential applications for control.

Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming (2023)
Journal Article
Hyland, M., Mennan, C., Davies, R., Wilson, E., Tonge, D. P., Clayton, A., & Kehoe, O. (2023). Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming. Stem Cell Reviews and Reports, 19, 2391–2406. https://doi.org/10.1007/s12015-023-10586-2

Autoimmune conditions, such as rheumatoid arthritis, are characterised by a loss of immune tolerance, whereby the immune cells attack self-antigens causing pain and inflammation. These conditions can be brought into remission using pharmaceutical tre... Read More about Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming.

Parasite exchange and hybridisation at a wild-feral-domestic interface (2023)
Journal Article
Smith, W. J., Jezierski, M. T., Dunn, J. C., & Clegg, S. M. (2023). Parasite exchange and hybridisation at a wild-feral-domestic interface. International Journal for Parasitology, 53(14), 797-808. https://doi.org/10.1016/j.ijpara.2023.06.005

Interactions between wild, feral, and domestic animals are of economic and conservation significance. The pigeon Columba livia is a synanthropic species in a feral form, but it also includes the rare Rock Dove. Columba livia is an important player at... Read More about Parasite exchange and hybridisation at a wild-feral-domestic interface.

Bird species with wider geographical ranges have higher blood parasite diversity but not prevalence across the African-Eurasian flyway (2023)
Journal Article
La Chapelle, M., Ruta, M., & Dunn, J. C. (2023). Bird species with wider geographical ranges have higher blood parasite diversity but not prevalence across the African-Eurasian flyway. International Journal for Parasitology, 53(14), 787-796. https://doi.org/10.1016/j.ijpara.2023.06.002

Avian blood parasites, from the genera Plasmodium, Haemoproteus and Leucocytozoon, are predicted to alter their range and prevalence as global temperatures change, and host and vector ranges shift. Understanding large-scale patterns in the prevalence... Read More about Bird species with wider geographical ranges have higher blood parasite diversity but not prevalence across the African-Eurasian flyway.

Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues. (2023)
Journal Article
Fezza, E., Roberts, J. M., Bruce, T. J. A., Walsh, L. E., Gaffney, M. T., Pope, T. W., …Gaffney, M. T. (in press). Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues. Pest Management Science, 10.1002/ps.7665. https://doi.org/10.1002/ps.7665

Monitoring is an integral component of integrated pest management (IPM) programmes used to inform crop management decisions. Vine weevil, Otiorhynchus sulcatus F. (Coleoptera: Curculionidae), continues to cause economically significant losses in hort... Read More about Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues..

Within- and between-host dynamics of producer and non-producer pathogens (2023)
Journal Article
Pike, V. L., Stevens, E. J., Griffin, A. S., & King, K. C. (2023). Within- and between-host dynamics of producer and non-producer pathogens. Parasitology, https://doi.org/10.1017/S0031182023000586

For infections to be maintained in a population, pathogens must compete to colonize hosts and transmit between them. We use an experimental approach to investigate within-and-between host dynamics using the pathogen Pseudomonas aeruginosa and the ani... Read More about Within- and between-host dynamics of producer and non-producer pathogens.