All Outputs (362)

Under‐Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participation (2025)
Journal Article
Bolton, M. J., Chew‐Graham, C. A., & van Marwijk, H. (in press). Under‐Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participation. Health Expectations, 28(2), 1-5. https://doi.org/10.1111/hex.70214

Public involvement in research and other initiatives for myalgic encephalomyelitis (ME) (also known as chronic fatigue syndrome) has been crucial in raising awareness of the disease and exposing inadequate healthcare and research funding. An online w... Read More about Under‐Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participation.

Process evaluation of the BASIL+ trial: A behavioural activation approach to addressing low mood and depression among older people with long-term conditions (2025)
Journal Article
Newbronner, E., Bosanquet, K., Coventry, P., Shearsmith, L., Littlewood, E., Bailey, D., …Chew-Graham, C. (in press). Process evaluation of the BASIL+ trial: A behavioural activation approach to addressing low mood and depression among older people with long-term conditions. PLOS Mental Health, 2(1), 1-15. https://doi.org/10.1371/journal.pmen.0000105

Older adults are at risk of low mood and depression, which can be exacerbated by long-term physical health conditions, leading to poorer health outcomes and increased mortality. The restrictions on social mixing during the COVID-19 pandemic heightene... Read More about Process evaluation of the BASIL+ trial: A behavioural activation approach to addressing low mood and depression among older people with long-term conditions.

Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial (2025)
Journal Article
Wang, H.-I., Gilbody, S., Littlewood, E., Baird, K., Ekers, D., McMillan, D., …Parrott, S. (2025). Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial. BMJ Mental Health, 28(1), 1-9. https://doi.org/10.1136/bmjment-2024-301270

Background: Depression alongside multiple long-term conditions (MLTCs) in older adults poses a critical public health challenge, worsening physical and mental health and increasing healthcare costs. COVID-19 restrictions further exacerbated these imp... Read More about Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared with usual care: results from a pragmatic randomised controlled trial.

Maternal perinatal anxiety and infant primary care use in 1998–2016: a UK cohort study (2025)
Journal Article
Smith, H. C., Archer, C., Bailey, J., Chew Graham, C., Evans, J., Fisher, T., …Petersen, I. (2025). Maternal perinatal anxiety and infant primary care use in 1998–2016: a UK cohort study. BMJ Mental Health, 28(1), 1-8. https://doi.org/10.1136/bmjment-2024-301160

There is some evidence that perinatal anxiety (PNA) is associated with lower rates of infant vaccinations and decreased access to preventative infant healthcare, but results across studies have not been conclusive. To investigate the relationship bet... Read More about Maternal perinatal anxiety and infant primary care use in 1998–2016: a UK cohort study.

AB0359 Assessing depression in patients with established rheumatoid arthritis-how do different approaches compare? (2025)
Journal Article
Hider, S., Ryan, S., Dale, N., Stanyer, N., Machin, A., & Chew-Graham, C. (in press). AB0359 Assessing depression in patients with established rheumatoid arthritis-how do different approaches compare?. Annals of the Rheumatic Diseases, 76(2), 1174. https://doi.org/10.1136/annrheumdis-2017-eular.5996

Background
Depression is common in patients with rheumatoid arthritis and negatively impacts on their quality of life and disease outcomes, including disease activity and treatment response. Several case-finding t... Read More about AB0359 Assessing depression in patients with established rheumatoid arthritis-how do different approaches compare?.

Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey (2024)
Journal Article
Austin, R., Khair, E., Blakeman, T., Hossain, M. Z., Sowden, E., Chew-Graham, C., …Deaton, C. (2024). Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey. BMJ Open, 14(12), bmjopen-2024-092993. https://doi.org/10.1136/bmjopen-2024-092993

Aim: As heart failure (HF) with preserved ejection fraction (HFpEF) prevalence increases, it remains frequently underdiagnosed and poorly managed. Recent positive pharmacological trials have increased interest in HFpEF but challenges of diagnosis and... Read More about Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey.

Medical ambivalence and Long Covid: The disconnects, entanglements, and productivities shaping ethnic minority experiences in the UK (2024)
Journal Article
Ridge, D. T., Broom, A., Alwan, N. A., Chew-Graham, C. A., Smyth, N., Gopal, D., …Begum, S. (2024). Medical ambivalence and Long Covid: The disconnects, entanglements, and productivities shaping ethnic minority experiences in the UK. Social Science and Medicine, Article 117603. https://doi.org/10.1016/j.socscimed.2024.117603

Structural violence - related to ‘isms’ like racism, sexism, and ableism – pertains to the ways in which social institutions harm certain groups. Such violence is critical to institutional indifference to the plight of ethnic minori... Read More about Medical ambivalence and Long Covid: The disconnects, entanglements, and productivities shaping ethnic minority experiences in the UK.

Involving People With Lived Experience in Electronic Health Record Database Studies Reflections and Learning From the CHOOSE Study (2024)
Journal Article
Cockcroft, E., Bassi, V., Mok, P. L. H., Adams, A., Claro, A. A., Trafford, A. M., …Chew‐Graham, C. A. (2024). Involving People With Lived Experience in Electronic Health Record Database Studies Reflections and Learning From the CHOOSE Study. Health Expectations, 27(6), Article e70131. https://doi.org/10.1111/hex.70131

Background: Patient and public involvement and engagement (PPIE) is integral to health research. Reporting of PPIE methods and impact is becoming increasingly common in health research. However, reporting on PPIE in studies using large, routinely col... Read More about Involving People With Lived Experience in Electronic Health Record Database Studies Reflections and Learning From the CHOOSE Study.

The Value of Clinical Prediction Models in General Practice: A Qualitative Study Exploring the Perspectives of People With Lived Experience of Depression and General Practitioners (2024)
Journal Article
Moriarty, A. S., Castleton, J., McMillan, D., Riley, R. D., Snell, K. I. E., Archer, L., …Chew‐Graham, C. A. (2024). The Value of Clinical Prediction Models in General Practice: A Qualitative Study Exploring the Perspectives of People With Lived Experience of Depression and General Practitioners. Health Expectations, 27(6), Article e70059. https://doi.org/10.1111/hex.70059

Introduction: Prediction models are increasingly being used to guide clinical decision making in primary care. There is a lack of evidence exploring the views of patients and general practitioners (GPs) in primary care around their use and implementa... Read More about The Value of Clinical Prediction Models in General Practice: A Qualitative Study Exploring the Perspectives of People With Lived Experience of Depression and General Practitioners.

The social determinants of distress in South Asian men with long-term conditions: a qualitative study (2024)
Journal Article
Awan, H., Corp, N., Kingstone, T., & Chew-Graham, C. A. (in press). The social determinants of distress in South Asian men with long-term conditions: a qualitative study. British Journal of General Practice (BJGP), https://doi.org/10.3399/bjgp.2024.0386

Background: People with long-term physical conditions are more likely to experience distress, depression or anxiety. Physical-mental comorbidity is associated with lower quality of life, poorer clinical outcomes, and increased mortality than physical... Read More about The social determinants of distress in South Asian men with long-term conditions: a qualitative study.

Understanding How, Why and for Whom Link Work Interventions Promote Access in Community Healthcare Settings in the United Kingdom: A Realist Review (2024)
Journal Article
Golby, R., Lobban, F., Laverty, L., Velemis, K., Aggarwal, V. R., Berry, K., …Palmier‐Claus, J. (2024). Understanding How, Why and for Whom Link Work Interventions Promote Access in Community Healthcare Settings in the United Kingdom: A Realist Review. Health Expectations, 27(6), Article e70090. https://doi.org/10.1111/hex.70090

Introduction: Inequity in access to healthcare in the United Kingdom can have a profound impact on people's ability to manage their health problems. Link work interventions attempt to overcome the socioeconomic and structural barriers that perpetuate... Read More about Understanding How, Why and for Whom Link Work Interventions Promote Access in Community Healthcare Settings in the United Kingdom: A Realist Review.

Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies (2024)
Journal Article
Moriarty, A. S., Paton, L. W., Snell, K. I., Archer, L., Riley, R. D., Buckman, J. E., …McMillan, D. (2024). Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies. BMJ Mental Health, 27(1), https://doi.org/10.1136/bmjment-2024-301226

Background: Relapse of depression is common and contributes to the overall associated morbidity and burden. We lack evidence-based tools to estimate an individual’s risk of relapse after treatment in primary care, which may help us more effectively t... Read More about Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies.

Supporting Long Covid Care: a webtool to facilitate help-seeking among people with Long Covid (2024)
Journal Article
Clutterbuck, D., Smyth, N., Begum, F., Chew-Graham, C., Mcgowan, A., Pantelic, M., …Alwan, N. A. (2024). Supporting Long Covid Care: a webtool to facilitate help-seeking among people with Long Covid. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.1822

Background Long Covid (also known as Post-COVID19 Condition or Post-COVID Syndrome) is characterised by persistent symptoms following SARSCoV2 infection not explained by other pathology. Some evidence suggests that people from marginalised communitie... Read More about Supporting Long Covid Care: a webtool to facilitate help-seeking among people with Long Covid.

Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial (2024)
Journal Article
Husain, N., Lunat, F., Lovell, K., Miah, J., Chew-Graham, C. A., Bee, P., …Morriss, R. (2024). Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial. The Lancet, 404(10461), 1430-1443. https://doi.org/10.1016/S0140-6736%2824%2901612-X

Postnatal depression necessitates timely and effective interventions to mitigate adverse maternal and child outcomes in the short term and over the life course. British south Asian women with depression are often underserved and undertreated due to s... Read More about Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial.

Co‐Producing a Package of Novel Online Resources to Support the Mental Health Needs of People With Persistent Pain: BeeFree (2024)
Journal Article
Stevenson, K., Evans, N., Campbell, L., Callaghan, P., Lench, J., McDonald, J., …Kingstone, T. (2024). Co‐Producing a Package of Novel Online Resources to Support the Mental Health Needs of People With Persistent Pain: BeeFree. Musculoskeletal Care, 22(4), 1-5. https://doi.org/10.1002/msc.1960

1 Background
Low back pain and depression are the leading causes of disability in the UK (Steel et al. 2018). Persistent pain (over 3 months) affects between one-in-three and one-in-two people in the UK (Fayaz et al. 2016). Mental health problems (s... Read More about Co‐Producing a Package of Novel Online Resources to Support the Mental Health Needs of People With Persistent Pain: BeeFree.

The role of primary care in depression relapse: a qualitative study. (2024)
Journal Article
Moriarty, A. S., Williams, E., McMillan, D., Gilbody, S., & Chew-Graham, C. A. (in press). The role of primary care in depression relapse: a qualitative study. British Journal of General Practice (BJGP), 1-28. https://doi.org/10.3399/BJGP.2024.0384

Background Relapse contributes to the clinical and societal burden associated with depression. It is not well understood how relapse risk and prevention are managed and discussed between patients and general practitioners in primary care. Aim To unde... Read More about The role of primary care in depression relapse: a qualitative study..

Defining the Role of the Fire and Rescue Service in Mental Health Support for Older Adults: A Qualitative Study (2024)
Journal Article
Fisher, T., Chew‐Graham, C. A., Corp, N., Farooq, S., Kingston, P., Read, I., …Kingstone, T. (2024). Defining the Role of the Fire and Rescue Service in Mental Health Support for Older Adults: A Qualitative Study. Health Expectations, 27(5), Article e70028. https://doi.org/10.1111/hex.70028

Introduction: Anxiety and depression in older adults (60+ years of age) are under‐diagnosed and under‐treated. Older adults are less likely to seek help for these problems due to a lack of awareness, difficulty accessing health care due to availabili... Read More about Defining the Role of the Fire and Rescue Service in Mental Health Support for Older Adults: A Qualitative Study.

Experience of choice of treatment for adults with depression: a systematic review and meta-synthesis of qualitative research (2024)
Journal Article
Megnin-Viggars, O., O’Donoghue, K., Pilling, S., & Chew-Graham, C. (in press). Experience of choice of treatment for adults with depression: a systematic review and meta-synthesis of qualitative research. Journal of Mental Health, 1-18. https://doi.org/10.1080/09638237.2024.2390369

Background
Treatment choices for depression are preference-sensitive (no “single best option”). However, factors or attributes that can enhance or inhibit patient choice have not been fully explored.

Aims
To synthesize the qualitative literature... Read More about Experience of choice of treatment for adults with depression: a systematic review and meta-synthesis of qualitative research.

Exploring General Practitioners' Management of Self‐Harm in Young People: A Qualitative Study (2024)
Journal Article
Mughal, F., Saunders, B., Lewis, M., J. Armitage, C., Dikomitis, L., Lancaster, G., …A. Chew‐Graham, C. (2024). Exploring General Practitioners' Management of Self‐Harm in Young People: A Qualitative Study. Health Expectations, 27(5), Article e70026. https://doi.org/10.1111/hex.70026

Background: General practitioners (GPs) are key to the frontline assessment and treatment of young people after self‐harm. Young people value GP‐led self‐harm care, but little is known about how GPs manage young people after self‐harm. Aim: This stud... Read More about Exploring General Practitioners' Management of Self‐Harm in Young People: A Qualitative Study.

Aripiprazole/Sertraline Combination: Clinical and Cost‐Effectiveness in Comparison With Quetiapine for the Treatment of Bipolar Depression (ASCEnD Trial)—Protocol for a Nested Qualitative Study (2024)
Journal Article
Hoppe, I., Watson, S., Kemp, C., Turnbull, F., Davies, F., Gibson, J., …Chew‐Graham, C. A. (2024). Aripiprazole/Sertraline Combination: Clinical and Cost‐Effectiveness in Comparison With Quetiapine for the Treatment of Bipolar Depression (ASCEnD Trial)—Protocol for a Nested Qualitative Study. Health Expectations, 27(5), Article e70018. https://doi.org/10.1111/hex.70018

Introduction
Bipolar disorder is a recurrent mental health disorder with a prevalence rate of 1.4%. On average, there can be a delay of 9.5 years from the initial presentation of symptoms to a confirmed diagnosis. Individuals living with bipolar dis... Read More about Aripiprazole/Sertraline Combination: Clinical and Cost‐Effectiveness in Comparison With Quetiapine for the Treatment of Bipolar Depression (ASCEnD Trial)—Protocol for a Nested Qualitative Study.