Objectives End of life has unacceptable levels of hospital admission and death. We aimed to determine the association of a novel digital specific system (Proactive Risk-Based and Data-Driven Assessment of Patients at the End of Life, PRADA) to modify... Read More about Digital health and inpatient palliative care: a cohort-controlled study.
Background Usual primary care for patients with musculoskeletal pain varies widely and treatment outcomes are suboptimal. Stratified care involves targeting treatments according to patient subgroups, in the hope of maximising treatment benefit and re... Read More about Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs.
“Hayah Karima” or “Decent Life” is a national initiative that aims to improve the quality of life and provide better services in rural and unplanned settlements in Egypt within the framework of the Sustainable Development Strategy: Egypt Vision 2030.... Read More about Securing sustainability and access to energy in low- and middle-income countries: opportunities for the ‘Hayah Karima’ programme in Egypt.
HPV causes about 5% of all cancers worldwide. The most common of these cancers is cervical but the virus is also implicated in cancers of the vagina, vulva, anus, penis, head and neck. A significant proportion of the cancers caused by HPV in Europe a... Read More about Improving HPV Vaccine Uptake in Children, Adolescents, and Young Adults: An Umbrella Review of Interventions.
The UK Critical National Infrastructure is critically dependent on digital technologies that provide communications, monitoring, control, and decision-support functionalities. Digital technologies are progressively enhancing efficiency, reliability,... Read More about Improving the Cybersecurity of Critical National Infrastructure using Modelling and Simulation.
Decolonising the Science Curriculum (2022)
Advance HE recognises there are different voices with differing views and approaches in the provision of higher education from around the world, this includes how insitution's may choose to enhance their curricula. This project is part of the 202... Read More about Decolonising the Science Curriculum.
Objectives The study aimed to provide a mapping review of non-pharmacological interventions to reduce restrictive practices in adult mental health inpatient settings; classify intervention components using the behaviour change technique taxonomy; ex... Read More about Non-pharmacological interventions to reduce restrictive practices in adult mental health inpatient settings: the COMPARE systematic mapping review.
In January 2019, the UK Government published its Maritime 2050 on Navigating the Future strategy. In the strategy, the government highlighted the importance of digitalization (with well-designed regulatory support) to achieve its goal of ensuring tha... Read More about The Internet of Things in Ports: Six Key Security and Governance Challenges for the UK (Policy Brief).
PURPOSE: Previous studies of hypofractionated adjuvant whole-breast radiotherapy for early breast cancer established a 15- or 16-fraction (fr) regimen as standard. The FAST Trial (CRUKE/04/015) evaluated normal tissue effects (NTE) and disease outcom... Read More about Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer..
We aimed to examine the association between pain, stiffness and fatigue in newly diagnosed polymyalgia rheumatica (PMR) patients using baseline data from a prospective cohort study. Fatigue is a known, but often ignored symptom of PMR. Newly diagnose... Read More about The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study.
Objective To determine the natural history of flare-ups in knee osteoarthritis and their relation to physical exposures. Design Adults aged =45 years with a recent primary care consultation for knee OA/arthralgia completed a daily pen-and-paper... Read More about ‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis.
Trastuzumab (Herceptin) is used in neoadjuvant, adjuvant and metastatic breast cancer. Infusion reactions are a common side effect most of which are mild and easily managed, anaphylaxis occurs rarely. The summary of product characteristics recommends... Read More about Trastuzumab infusion reactions in breast cancer. Should we routinely observe after the first dose?.
The aim of this study is to compare the prevalence of cardiovascular (CVD)-related comorbidities in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) or psoriasis (Ps) in UK primary care against matched cohorts. Matched retrospecti... Read More about Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study..
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the benefits and harms of community-based exercise and physical activity programmes led by non-healthcare exercise professionals for osteoarthriti... Read More about Community-based exercise and physical activity programmes led by exercise professionals for osteoarthritis.