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A randomised trial evaluating anakinra in early active rheumatoid arthritis. (2016)
Journal Article
Scott, I. C., Ibrahim, F., Simpson, G., Kowalczyk, A., White-Alao, B., Hassell, A., …Scott, D. L. (2016). A randomised trial evaluating anakinra in early active rheumatoid arthritis. Clinical and Experimental Rheumatology, 34(1), 88-93

OBJECTIVES:
The effectiveness of anakinra (interleukin-1 receptor antagonist) in early rheumatoid arthritis (RA) is unknown. We evaluated the efficacy of anakinra (combined with methotrexate) in a randomised clinical trial of early active RA patient... Read More about A randomised trial evaluating anakinra in early active rheumatoid arthritis..

A class of reduced-order models in the theory of waves and stability (2016)
Journal Article
Chapman, C., & Sorokin, S. (2016). A class of reduced-order models in the theory of waves and stability. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, https://doi.org/10.1098/rspa.2015.0703

This paper presents a class of approximations to a type of wave field for which the dispersion relation is transcendental. The approximations have two defining characteristics: (i) they give the field shape exactly when the frequency and wavenumber l... Read More about A class of reduced-order models in the theory of waves and stability.

New Transit Observations for HAT-P-30 b, HAT-P-37 b, TrES-5 b, WASP-28 b, WASP-36 b and WASP-39 b (2016)
Journal Article
Maciejewski, G., Dimitrov, D., Mancini, L., Southworth, J., Ciceri, S., D'Ago, G., …Henning, T. (2016). New Transit Observations for HAT-P-30 b, HAT-P-37 b, TrES-5 b, WASP-28 b, WASP-36 b and WASP-39 b. Acta Astronomica, 66(1), 55 - 74

We present new transit light curves for planets in six extrasolar planetary systems. They were acquired with 0.4-2.2 m telescopes located in west Asia, Europe, and South America. When combined with literature data, they allowed us to redetermine syst... Read More about New Transit Observations for HAT-P-30 b, HAT-P-37 b, TrES-5 b, WASP-28 b, WASP-36 b and WASP-39 b.

Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation (2016)
Journal Article
Wright, K., & Roberts, S. (2016). Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation. Stem Cells International, 5415901 - ?

Much emphasis has been placed recently on the repair of degenerate discs using implanted cells, such as disc cells or bone marrow derived mesenchymal stem cells (MSCs). This study examines the temporal response of bovine and human nucleus pulposus (N... Read More about Temporal Analyses of the Response of Intervertebral Disc Cells and Mesenchymal Stem Cells to Nutrient Deprivation.

Refined boundary conditions on the free surface of an elastic half-space taking into account non-local effects (2016)
Journal Article
Kaplunov. (2016). Refined boundary conditions on the free surface of an elastic half-space taking into account non-local effects. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, https://doi.org/10.1098/rspa.2015.0800

The dynamic response of a homogeneous half-space, with a traction-free surface, is considered within the framework of non-local elasticity. The focus is on the dominant effect of the boundary layer on overall behaviour. A typical wavelength is assume... Read More about Refined boundary conditions on the free surface of an elastic half-space taking into account non-local effects.

What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOme (2016)
Journal Article
Tonge, D., & Gant, T. (2016). What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOme. BMC Molecular Biology, https://doi.org/10.1186/s12867-016-0057-9

Background
MicroRNAs (miRNAs) are short non-protein-coding RNA species that have a regulatory function in modulating protein translation and degradation of specific mRNAs. MicroRNAs are estimated to target approximately 60 % of all human mRNAs and a... Read More about What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOme.

ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country (2016)
Journal Article
Bajpai. (2016). ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country. Pediatric Blood and Cancer, 1024 - 1030. https://doi.org/10.1002/pbc.25935

Background
As Hodgkin lymphoma (HL) is a highly curable malignancy, most current pediatric trials focus on strategies aimed at reducing late effects of therapy. We report our results with doxorubicin, bleomycin, vinblastine, dacarbazine (ABVD) thera... Read More about ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country.

The banality of bad leadership and followership (2016)
Journal Article
(2016). The banality of bad leadership and followership. Society and Business Review, 12 - 23. https://doi.org/10.1108/SBR-09-2015-0049

The purpose of this paper is to highlight the loss of moral capital incurred by an organization from indifferent or deferential followers of bad leaders. Despite the proliferation of codes of conduct and ethics and compliance programs throughout the... Read More about The banality of bad leadership and followership.

Development of Multifunctional Magnetic Nanoparticles for Genetic Engineering and Tracking of Neural Stem Cells (2016)
Journal Article
Adams, C., Israel, L. L., Ostrovsky, S., Taylor, A., Poptani, H., Lellouche, J., & Chari, D. (2016). Development of Multifunctional Magnetic Nanoparticles for Genetic Engineering and Tracking of Neural Stem Cells. Advanced healthcare materials, 5(7), 841-849. https://doi.org/10.1002/adhm.201500885

Genetic modification of cell transplant populations and cell tracking ability are key underpinnings for effective cell therapies. Current strategies to achieve these goals utilize methods which are unsuitable for clinical translation because of relat... Read More about Development of Multifunctional Magnetic Nanoparticles for Genetic Engineering and Tracking of Neural Stem Cells.

A 250-year periodicity in Southern Hemisphere westerly winds over the last 2600 years (2016)
Journal Article
(2016). A 250-year periodicity in Southern Hemisphere westerly winds over the last 2600 years. Climate of the Past, 189 -200. https://doi.org/10.5194/cp-12-189-2016

Southern Hemisphere westerly airflow has a significant influence on the ocean-atmosphere system of the mid-to high latitudes with potentially global climate implications. Unfortunately, historic observations only extend back to the late 19th century,... Read More about A 250-year periodicity in Southern Hemisphere westerly winds over the last 2600 years.

The Novel Sequence (2016)
Book Chapter
Bentley. (2016). The Novel Sequence. In P. Boxall, & B. Cheyette (Eds.), The Oxford History of the Novel in English, Volume 7: British and Irish Fiction Since 1940 (258--271). Oxford University Press. https://doi.org/10.1093/oso/9780198749394.003.0017

This chapter examines the novel sequence. The novel sequence has been an important part of British and Irish literary output in the period since 1940, with examples in all the major genres and modes of fiction. The post-Second World War period repres... Read More about The Novel Sequence.

Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial (2016)
Journal Article
Tallon, D., Wiles, N., Campbell, J., Chew-Graham, C., Dickens, C., Macleod, U., …Kessler, D. (2016). Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial. Trials, 17, 66. https://doi.org/10.1186/s13063-016-1199-2

Background
People with depression are usually managed in primary care and antidepressants are often the first-line treatment, but only one third of patients respond fully to a single antidepressant. This paper describes the protocol for a randomised... Read More about Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial.

The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells (2016)
Journal Article
(2016). The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells. Oncotarget, https://doi.org/10.18632/oncotarget.7173

Growth arrest-specific 5 (GAS5) lncRNA promotes apoptosis, and its expression is down-regulated in breast cancer. GAS5 lncRNA is a decoy of glucocorticoid/related receptors; a stem-loop sequence constitutes the GAS5 hormone response element mimic (HR... Read More about The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells.

The OA Trial Bank: meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids (2016)
Journal Article
van Middelkoop, M., Arden, N. K., Atchia, I., Birrell, F., Chao, J., Rezende, M. U., …Bierma-Zeinstra, S. M. A. (2016). The OA Trial Bank: meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids. Osteoarthritis and Cartilage, 24(7), 1143-1152. https://doi.org/10.1016/j.joca.2016.01.983

Wolf-Rayet stars as an evolved stage of stellar life (2016)
Conference Proceeding
Georgy, C., Ekström, S., Hirschi, R., Meynet, G., Groh, J., & Eggenberger, P. (2016). Wolf-Rayet stars as an evolved stage of stellar life. In Wolf-Rayet Stars: Proceedings of an International Workshop held in Potsdam, Germany, 1.–5. June 2015

Wolf-Rayet (WR) stars, as they are advanced stages of the life of massive stars, provide a good test for various physical processes involved in the modelling of massive stars, such as rotation and mass loss. In this paper, we show the outputs of the... Read More about Wolf-Rayet stars as an evolved stage of stellar life.

The Global Implications of the Hard Excess II: Analysis of the Local population of Radio Quiet AGN (2016)
Journal Article
(2016). The Global Implications of the Hard Excess II: Analysis of the Local population of Radio Quiet AGN. Astrophysical Journal, https://doi.org/10.3847/0004-637X/818/1/12

Active galactic nuclei (AGN) show evidence for reprocessing gas, outflowing from the accreting black hole. The combined effects of absorption and scattering from the circumnuclear material likely explains the `hard excess' of X-ray emission above 20... Read More about The Global Implications of the Hard Excess II: Analysis of the Local population of Radio Quiet AGN.