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Effectiveness of low dose computed tomography to detect fractures in paediatric suspected physical abuse: a systematic review. (2024)
Journal Article
Doyle, E., Bugeja, L., Dimmock, M. R., Lee, K. L., Ng, J., & Bassed, R. B. (in press). Effectiveness of low dose computed tomography to detect fractures in paediatric suspected physical abuse: a systematic review. International Journal of Legal Medicine, https://doi.org/10.1007/s00414-024-03214-2

The skeletal survey X-ray series is the current 'gold standard' when investigating suspected physical abuse (SPA) of children, in addition to a non-contrast computed tomography (CT) brain scan. This systematic literature review synthesised findings o... Read More about Effectiveness of low dose computed tomography to detect fractures in paediatric suspected physical abuse: a systematic review..

Brainstem processing of cough sensory inputs in chronic cough hypersensitivity. (2024)
Journal Article
Moe, A. A. K., Singh, N., Dimmock, M., Cox, K., McGarvey, L., Chung, K. F., …Mazzone, S. B. (2024). Brainstem processing of cough sensory inputs in chronic cough hypersensitivity. EBioMedicine, 100, Article 104976. https://doi.org/10.1016/j.ebiom.2024.104976

Background
Chronic cough is a prevalent and difficult to treat condition often accompanied by cough hypersensitivity, characterised by cough triggered from exposure to low level sensory stimuli. The mechanisms underlying cough hypersensitivity may i... Read More about Brainstem processing of cough sensory inputs in chronic cough hypersensitivity..

Proton versus photon therapy for high-risk prostate cancer with dose escalation of dominant intraprostatic lesions: a preliminary planning study (2023)
Journal Article
Ong, A. L. K., Knight, K., Panettieri, V., Dimmock, M., Tuan, J. K. L., Tan, H. Q., & Wright, C. (in press). Proton versus photon therapy for high-risk prostate cancer with dose escalation of dominant intraprostatic lesions: a preliminary planning study. Frontiers in oncology, 13, 1241711. https://doi.org/10.3389/fonc.2023.1241711

Background and purpose: This study aimed to investigate the feasibility of safe-dose escalation to dominant intraprostatic lesions (DILs) and assess the clinical impact using dose-volume (DV) and biological metrics in photon and proton therapy. Biolo... Read More about Proton versus photon therapy for high-risk prostate cancer with dose escalation of dominant intraprostatic lesions: a preliminary planning study.

Comparison of typical radiation doses and risks using an anthropomorphic ‘bone fracture’ phantom for commonly performed X‐ray projections in a 5‐year‐old (2023)
Journal Article
Doyle, E., Dimmock, M. R., Lee, K. L., Thomas, P., & Bassed, R. B. (in press). Comparison of typical radiation doses and risks using an anthropomorphic ‘bone fracture’ phantom for commonly performed X‐ray projections in a 5‐year‐old. Journal of Medical Radiation Sciences, https://doi.org/10.1002/jmrs.717

Introduction: Diagnostic reference levels (DRLs) are typical dose levels for medical imaging examinations for groups of standard‐sized patients or standard phantoms for broadly defined types of equipment used as a tool to aid optimisation of protecti... Read More about Comparison of typical radiation doses and risks using an anthropomorphic ‘bone fracture’ phantom for commonly performed X‐ray projections in a 5‐year‐old.

Predictors for late genitourinary toxicity in men receiving radiotherapy for high-risk prostate cancer using planned and accumulated dose. (2023)
Journal Article
Kit Loong Tuan, J., Qi Tan, H., Li Kuan Ong, A., Knight, K., Panettieri, V., Dimmock, M., & Wright, C. (2023). Predictors for late genitourinary toxicity in men receiving radiotherapy for high-risk prostate cancer using planned and accumulated dose. https://doi.org/10.1016/j.phro.2023.100421

BACKGROUND AND PURPOSE: Significant deviations between bladder dose planned (DP) and dose accumulated (DA) have been reported in patients receiving radiotherapy for prostate cancer. This study aimed to construct multivariate analysis (MVA) models to... Read More about Predictors for late genitourinary toxicity in men receiving radiotherapy for high-risk prostate cancer using planned and accumulated dose..

Predictive modelling for late rectal and urinary toxicities after prostate radiotherapy using planned and delivered dose. (2022)
Journal Article
Knight, K., Panettieri, V., Dimmock, M., Tuan, J., Tan, H., Wright, C., & Ong, A. (2022). Predictive modelling for late rectal and urinary toxicities after prostate radiotherapy using planned and delivered dose. Frontiers in oncology, 1084311 - ?. https://doi.org/10.3389/fonc.2022.1084311

BACKGROUND AND PURPOSE: Normal tissue complication probability (NTCP) parameters derived from traditional 3D plans may not be ideal in defining toxicity outcomes for modern radiotherapy techniques. This study aimed to derive parameters of the Lyman-K... Read More about Predictive modelling for late rectal and urinary toxicities after prostate radiotherapy using planned and delivered dose..

Imaging Breast Microcalcifications Using Dark-Field Signal in Propagation-Based Phase-Contrast Tomography. (2022)
Journal Article
Aminzadeh, A., Arhatari, B., Maksimenko, A., Hall, C., Hausermann, D., Peele, A., …Lockie, D. (2022). Imaging Breast Microcalcifications Using Dark-Field Signal in Propagation-Based Phase-Contrast Tomography. IEEE Transactions on Medical Imaging, 2980 - 2990. https://doi.org/10.1109/TMI.2022.3175924

Breast microcalcifications are an important primary radiological indicator of breast cancer. However, microcalcification classification and diagnosis may be still challenging for radiologists due to limitations of the standard 2D mammography techniqu... Read More about Imaging Breast Microcalcifications Using Dark-Field Signal in Propagation-Based Phase-Contrast Tomography..

Typical median effective radiation doses using an anthropomorphic bone fracture phantom for initial radiographic skeletal surveys in the investigation of suspected physical abuse. (2022)
Journal Article
Doyle, E., Dimmock, M., Lee, K., Thomas, P., & Bassed, R. (2022). Typical median effective radiation doses using an anthropomorphic bone fracture phantom for initial radiographic skeletal surveys in the investigation of suspected physical abuse. Pediatric Radiology, https://doi.org/10.1007/s00247-022-05456-x

BACKGROUND: A series of 31 radiographs is recommended by the Royal College of Radiologists (RCR) when investigating suspected physical abuse (SPA). OBJECTIVE: To determine the radiation dose delivered for skeletal surveys performed for SPA in Victori... Read More about Typical median effective radiation doses using an anthropomorphic bone fracture phantom for initial radiographic skeletal surveys in the investigation of suspected physical abuse..

Dose-volume analysis of planned versus accumulated dose as a predictor for late gastrointestinal toxicity in men receiving radiotherapy for high-risk prostate cancer. (2022)
Journal Article
Ong, A., Knight, K., Panettieri, V., Dimmock, M., Tuan, J., Tan, H., & Wright, C. (2022). Dose-volume analysis of planned versus accumulated dose as a predictor for late gastrointestinal toxicity in men receiving radiotherapy for high-risk prostate cancer. https://doi.org/10.1016/j.phro.2022.07.001

Background and purpose: Significant dose deviations have been reported between planned (DP) and accumulated (DA) dose in prostate radiotherapy. This study aimed to develop multivariate analysis (MVA) models associating Grade 1 and 2 gastrointestinal... Read More about Dose-volume analysis of planned versus accumulated dose as a predictor for late gastrointestinal toxicity in men receiving radiotherapy for high-risk prostate cancer..

Designing a breast support device for phase contrast tomographic imaging: getting ready for a clinical trial (2022)
Journal Article
Dimmock, M., McKinley, J., Massey, A., Hausermann, D., Tam, N., Stewart, E., …Lewis, S. J. (2022). Designing a breast support device for phase contrast tomographic imaging: getting ready for a clinical trial. British Journal of Radiology, 95(1138), Article ARTN 20211243. https://doi.org/10.1259/bjr.20211243

Objective
To design a device that can support the breast during phase-contrast tomography, and characterise its fit parameterisation and comfort rating.

Methods
27 participants were recruited to trial a system for breast support during simulated... Read More about Designing a breast support device for phase contrast tomographic imaging: getting ready for a clinical trial.

Immersive virtual reality simulated learning environment versus role-play for empathic clinical communication training. (2022)
Journal Article
Sapkaroski, D., Mundy, M., & Dimmock, M. (2022). Immersive virtual reality simulated learning environment versus role-play for empathic clinical communication training. Journal of Medical Radiation Sciences, 56 - 65. https://doi.org/10.1002/jmrs.555

INTRODUCTION: The use of immersive virtual reality simulated learning environments (VR SLEs) for improving clinical communication can offer desirable qualities including repetition and determinism in a safe environment. The aim of this study was to e... Read More about Immersive virtual reality simulated learning environment versus role-play for empathic clinical communication training..

Application of an automated dose accumulation workflow in high-risk prostate cancer - validation and dose-volume analysis between planned and delivered dose (2021)
Journal Article
Ong, A., Knight, K., Panettieri, V., Dimmock, M., Tuan, J. K. L., Tan, H. Q., …Wright, C. (2022). Application of an automated dose accumulation workflow in high-risk prostate cancer - validation and dose-volume analysis between planned and delivered dose. Medical Dosimetry, 47(1), 92-97. https://doi.org/10.1016/j.meddos.2021.09.004

Inter-fraction organ variations cause deviations between planned and delivered doses in patients receiving radiotherapy for prostate cancer. This study compared planned (DP) vs accumulated doses (DA) obtained from daily cone-beam computed tomography... Read More about Application of an automated dose accumulation workflow in high-risk prostate cancer - validation and dose-volume analysis between planned and delivered dose.

X-ray phase-contrast computed tomography for full breast mastectomy imaging at the Australian Synchrotron (2021)
Presentation / Conference
Arhatari, B. D., Nesterets, Y. I., Taba, S. T., Maksimenko, A., Hall, C. J., Stevenson, A. W., …Brennan, P. C. (2021, August). X-ray phase-contrast computed tomography for full breast mastectomy imaging at the Australian Synchrotron. Paper presented at Developments in X-Ray Tomography XIII, San Diego, United States

One of the imaging modalities offered by the Imaging and Medical Beamline (IMBL) at the Australian Synchrotron is Xray phase-contrast propagation-based computed tomography (PB-CT). The unique combination of high coherence and high brightness of radia... Read More about X-ray phase-contrast computed tomography for full breast mastectomy imaging at the Australian Synchrotron.

Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast (2021)
Journal Article
Wan, S., Arhatari, B. D., Nesterets, Y. I., Mayo, S. C., Thompson, D., Fox, J., …Taba, S. T. (2021). Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast. Journal of Medical Imaging, 8(05), https://doi.org/10.1117/1.jmi.8.5.052108

Purpose: Breast cancer is the most common cancer in women in developing and developed countries and is responsible for 15% of women’s cancer deaths worldwide. Conventional absorption-based breast imaging techniques lack sufficient contrast for compre... Read More about Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast.

X-ray Phase-Contrast Computed Tomography for Soft Tissue Imaging at the Imaging and Medical Beamline (IMBL) of the Australian Synchrotron (2021)
Journal Article
Hall, C., Thompson, D., Mayo, S., Fiala, T., Taba, S., Lewis, S., …Gureyev, T. (2021). X-ray Phase-Contrast Computed Tomography for Soft Tissue Imaging at the Imaging and Medical Beamline (IMBL) of the Australian Synchrotron. Applied Sciences, https://doi.org/10.3390/app11094120

The Imaging and Medical Beamline (IMBL) is a superconducting multipole wiggler-based beamline at the 3 GeV Australian Synchrotron operated by the Australian Nuclear Science and Technology Organisation (ANSTO). The beamline delivers hard X-rays in the... Read More about X-ray Phase-Contrast Computed Tomography for Soft Tissue Imaging at the Imaging and Medical Beamline (IMBL) of the Australian Synchrotron.

Propagation-Based Phase-Contrast CT of the Breast Demonstrates Higher Quality Than Conventional Absorption-Based CT Even at Lower Radiation Dose (2021)
Journal Article
Tavakoli Taba, S., Arhatari, B. D., Nesterets, Y. I., Gadomkar, Z., Mayo, S. C., Thompson, D., …Brennan, P. C. (2021). Propagation-Based Phase-Contrast CT of the Breast Demonstrates Higher Quality Than Conventional Absorption-Based CT Even at Lower Radiation Dose. Academic radiology, 28(1), e20-e26. https://doi.org/10.1016/j.acra.2020.01.009

Rationale and Objectives
Propagation-based phase-contrast CT (PB-CT) is an advanced X-ray imaging technology that exploits both refraction and absorption of the transmitted X-ray beam. This study was aimed at optimizing the experimental conditions o... Read More about Propagation-Based Phase-Contrast CT of the Breast Demonstrates Higher Quality Than Conventional Absorption-Based CT Even at Lower Radiation Dose.

Findings from machine learning in clinical medical imaging applications - Lessons for translation to the forensic setting. (2020)
Journal Article
Peña-Solórzano, C., Albrecht, D., Bassed, R., Burke, M., & Dimmock, M. (2020). Findings from machine learning in clinical medical imaging applications - Lessons for translation to the forensic setting. Forensic Science International, -. https://doi.org/10.1016/j.forsciint.2020.110538

Machine learning (ML) techniques are increasingly being used in clinical medical imaging to automate distinct processing tasks. In post-mortem forensic radiology, the use of these algorithms presents significant challenges due to variability in organ... Read More about Findings from machine learning in clinical medical imaging applications - Lessons for translation to the forensic setting..

Development of an automated radiotherapy dose accumulation workflow for locally advanced high-risk prostate cancer - A technical report. (2020)
Journal Article
Knight, K., Panettieri, V., Dimmock, M., Ong, A., Tuan, J., Tan, H., …Wright, C. (2020). Development of an automated radiotherapy dose accumulation workflow for locally advanced high-risk prostate cancer - A technical report. Journal of Medical Radiation Sciences, 203 - 210. https://doi.org/10.1002/jmrs.442

An automated dose accumulation and contour propagation workflow using daily cone beam computed tomography (CBCTs) images for prostate cases that require pelvic lymph nodes irradiation (PLNs) was developed. This workflow was constructed using MIM® sof... Read More about Development of an automated radiotherapy dose accumulation workflow for locally advanced high-risk prostate cancer - A technical report..