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Multimorbidity in Older Adults with Depression Study (MODS) (Behavioural Activation to improve physical and mental functioning among older people with multiple long-term conditions): Protocol for a fully powered randomised controlled trial
Journal Article
Ryde, E., Hollingsworth, K., Littlewood, E., Atha, L., Bailey, D., Baker, H., …Ekers, D. Multimorbidity in Older Adults with Depression Study (MODS) (Behavioural Activation to improve physical and mental functioning among older people with multiple long-term conditions): Protocol for a fully powered randomised controlled trial. MedRxiv, https://doi.org/10.1101/2024.01.10.24301134

Aedes aegyptigut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes
Journal Article
Hegde, S., Brettell, L. E., Quek, S., Etebari, K., Saldaña, M. A., Asgari, S., …Hughes, G. L. Aedes aegyptigut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes. arXiv, https://doi.org/10.1101/2023.03.16.532926

The mosquito microbiome is critical for host development and plays a major role in many aspects of mosquito biology. While the microbiome is commonly dominated by a small number of genera, there is considerable variation in composition among mosquito... Read More about Aedes aegyptigut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes.

Inter-species microbiota transplantation recapitulates microbial acquisition and persistence in mosquitoes
Journal Article
Coon, K. L., Hegde, S., & Hughes, G. L. Inter-species microbiota transplantation recapitulates microbial acquisition and persistence in mosquitoes. arXiv, https://doi.org/10.1101/2021.10.06.463328

Background Mosquitoes harbor microbial communities that play important roles in their growth, survival, reproduction, and ability to transmit human pathogens. Microbiome transplantation approaches are often used to study host-microbe interactions and... Read More about Inter-species microbiota transplantation recapitulates microbial acquisition and persistence in mosquitoes.

Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity.
Journal Article
Kozlova, E. V., Hegde, S., Roundy, C. M., Golovko, G., A Saldana, M., Hart, C. E., …Hughes, G. L. Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity. arXiv, https://doi.org/10.1101/2020.04.14.039701

How microbe-microbe interactions dictate microbial complexity in the mosquito gut is unclear. Previously we found that Serratia, a gut symbiont that alters vector competence and is being considered for vector control, poorly colonized Aedes aegypti y... Read More about Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity..

Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells
Journal Article
Hegde, S., Voronin, D., Casas-Sanchez, A., Saldaña, M. A., Heinz, E., Acosta-Serrano, A., …Hughes, G. L. Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells. arXiv, https://doi.org/10.1101/866897

Microbiota within mosquitoes influence nutrition, immunity, fecundity, and the capacity to transmit pathogens. Despite their importance, we have a limited understanding of host-microbiota interactions, especially at the cellular level. It is evident... Read More about Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells.

Genetic Diversity and Population Structure of the Invasive Oriental Fruit Fly, Bactrocera dorsalis (Diptera: Tephritidae) in Burkina Faso
Other
Traoré, N., Kientega, M., Maïga, H., Nebié, K., Zida, I., Galizi, R., …Diabaté, A. (2024). Genetic Diversity and Population Structure of the Invasive Oriental Fruit Fly, Bactrocera dorsalis (Diptera: Tephritidae) in Burkina Faso. [Preprint]

Bactrocera dorsalis Hendel is a highly invasive horticultural pest of major economic importance worldwide. In Burkina Faso, it is one of the main insect pests constraining the mango production and export. Understanding the biology and the genetic dyn... Read More about Genetic Diversity and Population Structure of the Invasive Oriental Fruit Fly, Bactrocera dorsalis (Diptera: Tephritidae) in Burkina Faso.

Identifying risk factors for Lassa fever infection in Sierra Leone, 2019-2021
Journal Article
Juma Sama, D., Haider, N., Guitian, J., Yusuf Osman, A., Ntoumi, F., Zumla, A., …Ansumana, R. Identifying risk factors for Lassa fever infection in Sierra Leone, 2019-2021. MedRxiv, https://doi.org/10.1101/2024.04.11.24305423

Background Lassa fever (LF) virus (LASV) is endemic in Sierra Leone and poses a significant public health threat to the region; however, no risk factors for LASV infection have been reported in Sierra Leone. The objective of this study was to identif... Read More about Identifying risk factors for Lassa fever infection in Sierra Leone, 2019-2021.

Ten Sefirot For Piano - Score
Other
Spasov, M. (2021). Ten Sefirot For Piano - Score. [PDF/Demo piece]

My main creative interest in this work is closely related to and influenced by the study of cognitive science and anthropology, particularly the parallels between musical structures and culturally influenced consciousness. In this piece, I draw inspi... Read More about Ten Sefirot For Piano - Score.

The curious case of Betelgeuse
Conference Proceeding
van Loon, J. T. (2023). The curious case of Betelgeuse. In The Sixteenth Marcel Grossmann Meeting On Recent Developments in Theoretical and Experimental General Relativity, Astrophysics, and Relativistic Field Theories (In 4 Volumes). https://doi.org/10.1142/9789811269776_0289

Betelgeuse is the nearest red supergiant, one of the brightest stars in our sky, and statistically speaking it would be expected to be “typical”. Yet it exhibits many features that seem “curious”, to say the least. For instance it has a high proper m... Read More about The curious case of Betelgeuse.