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#2796 Divergent associations between mortality and different measures of renal function after adjustment for body composition: results from the UK Biobank (2024)
Presentation / Conference
Tabinor, M., Potts, J., Ferro, C. J., Davies, S., & Solis-Trapala, I. (2024, May). #2796 Divergent associations between mortality and different measures of renal function after adjustment for body composition: results from the UK Biobank. Presented at 61st ERA Congress, Stockholm, Sweden

Background and Aims There is data suggesting estimated glomerular filtration rate using Cystatin-C (eGFRCystatin-C) is superior to the creatinine-based (eGFRCreat) method when assessing associations between renal function and mortality (Lees et al. 2... Read More about #2796 Divergent associations between mortality and different measures of renal function after adjustment for body composition: results from the UK Biobank.

#1248 Sex specific associations between fat free mass and weight with mortality: sequences of regressions analyses from the UK Biobank cohort (2024)
Presentation / Conference
Tabinor, M., Potts, J., Ferro, C. J., Davies, S., & Solis-Trapala, I. (2024, May). #1248 Sex specific associations between fat free mass and weight with mortality: sequences of regressions analyses from the UK Biobank cohort. Presented at 61st ERA Congress, Stockholm, Sweden

Background and Aims There is growing evidence that muscle mass (MM) loss, observed in long term conditions (LTCs), including chronic kidney disease (CKD), is associated with mortality. This study aimed to explore the direct association between MM and... Read More about #1248 Sex specific associations between fat free mass and weight with mortality: sequences of regressions analyses from the UK Biobank cohort.

Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England (2024)
Journal Article
Damery, S., Lambie, M., Williams, I., Coyle, D., Fotheringham, J., Solis-Trapala, I., …Davies, S. J. (in press). Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608241232200

Background: Disparities in home dialysis uptake across England suggest inequity and unexplained variation in access. We surveyed staff at all English kidney centres to identify patterns in service organisation/delivery and explore correlations with... Read More about Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England.

Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts (2020)
Journal Article
Shoaib, A., Johnson, T. W., Banning, A., Ludman, P., Rashid, M., Potts, J., …Mamas, M. A. (2020). Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts. Journal of Invasive Cardiology,

Background. There are limited data comparing outcomes of patients with previous coronary artery bypass grafting (CABG) presenting with stable angina who undergo percutaneous coronary intervention (PCI) to either a saphenous vein grafts (SVG) or a chr... Read More about Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts.

Corrigendum to: Percutaneous coronary intervention outcomes in patients with rheumatoid arthritis, systemic lupus erythematosus and systemic sclerosis (2020)
Journal Article
Martinez, S. C., Mohamed, M., Potts, J., Abhishek, A., Roddy, E., Savage, M., …Mamas, M. A. (2020). Corrigendum to: Percutaneous coronary intervention outcomes in patients with rheumatoid arthritis, systemic lupus erythematosus and systemic sclerosis. Rheumatology, 59(9), 2655. https://doi.org/10.1093/rheumatology/keaa101

Correction to https://doi.org/10.1093/rheumatology/kez639

Unplanned hospital readmissions after acute myocardial infarction: A nationwide analysis of rates, trends, predictors and causes in the United States between 2010 and 2014 (2020)
Journal Article
Capers I, Q., Fischmann, D., Kwok, C., Savage, M., Gulati, M., Potts, J., …Mamas, M. (2020). Unplanned hospital readmissions after acute myocardial infarction: A nationwide analysis of rates, trends, predictors and causes in the United States between 2010 and 2014. Coronary Artery Disease, 354-364. https://doi.org/10.1097/MCA.0000000000000844

Background Unplanned hospital readmissions are an important quality metric for benchmarking but there is limited data following an acute myocardial infarction (AMI). This study aims to examine the 30-day unplanned readmission rate, predictors, cause... Read More about Unplanned hospital readmissions after acute myocardial infarction: A nationwide analysis of rates, trends, predictors and causes in the United States between 2010 and 2014.

In-hospital Upper Gastrointestinal Bleeding Following Percutaneous Coronary Intervention (2020)
Journal Article
Zaman, A., Kinnaird, T., Mamas, M., Kontopantelis, E., Potts, J., Ayyaz Ul Haq, M., …Large, A. (2020). In-hospital Upper Gastrointestinal Bleeding Following Percutaneous Coronary Intervention. Catheterization and Cardiovascular Interventions, 109-117. https://doi.org/10.1002/ccd.28222

Objectives This study aims to examine in-hospital gastrointestinal (GI) bleeding, its predictors and clinical outcomes, including long-term outcomes, in a national cohort of patients undergoing percutaneous coronary intervention (PCI) in England and... Read More about In-hospital Upper Gastrointestinal Bleeding Following Percutaneous Coronary Intervention.

Acute myocardial infarction treatments and outcomes in 6.5 million patients with a current or historical diagnosis of cancer in the USA (2019)
Journal Article
Bharadwaj, A., Potts, J., Mohamed, M. O., Parwani, P., Swamy, P., Lopez-Mattei, J. C., …Mamas, M. A. (2020). Acute myocardial infarction treatments and outcomes in 6.5 million patients with a current or historical diagnosis of cancer in the USA. European Heart Journal, 41(23), 2183-2193. https://doi.org/10.1093/eurheartj/ehz851

Aim: The aim of this study is to evaluate temporal trends, treatment and clinical outcomes of patients who present with an acute myocardial infarction (AMI) and have a current or historical diagnosis of cancer, according to cancer type and presence... Read More about Acute myocardial infarction treatments and outcomes in 6.5 million patients with a current or historical diagnosis of cancer in the USA.

P681Acute Myocardial Infarction in patients with Leukaemia: A national analysis of prevalence, predictors and outcomes in United States hospitalisations (2004 to 2014) (2019)
Journal Article
Mohamed, M. O., Lopez-Mattei, J. C., Iliescu, C. A., Purwani, P., Bharadwaj, A., Kim, P. Y., …Mamas, M. (2019). P681Acute Myocardial Infarction in patients with Leukaemia: A national analysis of prevalence, predictors and outcomes in United States hospitalisations (2004 to 2014). European Heart Journal, 40(Supplement_1), https://doi.org/10.1093/eurheartj/ehz747.0287

Background Patients with leukaemia are at increased risk of cardiovascular events. There is limited outcomes data for patients with a history of leukaemia who present with an acute myocardial infarction (AMI). Purpose To examine the prevalence a... Read More about P681Acute Myocardial Infarction in patients with Leukaemia: A national analysis of prevalence, predictors and outcomes in United States hospitalisations (2004 to 2014).

Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses (2019)
Journal Article
Watson, L., Loke, Y., Mallen, C., Mamas, M., Gulati, M., Kwok, C., …Wu, P. (2019). Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses. European Journal of Preventive Cardiology, 26(13), 1415-1429. https://doi.org/10.1177/2047487319843667

Aims The optimal diet for cardiovascular health is controversial. The aim of this review is to summarize the highest level of evidence and rank the risk associated with each individual component of diet within its food group. Methods and results... Read More about Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses.

Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis (2019)
Journal Article
Potts, J., Mohamed, M., Lopez-Mattei, J., Iliescu, C., Konopleva, M., Mamas, M., …Bagur, R. (2019). Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis. Catheterization and Cardiovascular Interventions, https://doi.org/10.1002/ccd.28432

Objectives: To examine the association between current leukemia diagnosis and in-hospital clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) in the US. Background: Leukemia is most common hematological malignancy and... Read More about Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis.

The influence of Elixhauser comorbidity index on percutaneous coronary intervention outcomes (2019)
Journal Article
Potts, J., Nagaraja, V., Al suwaidi, J., Brugaletta, S., Martinez, S., Alraies, C., …Kwok, C. (2019). The influence of Elixhauser comorbidity index on percutaneous coronary intervention outcomes. Catheterization and Cardiovascular Interventions, 94(2), 195-203. https://doi.org/10.1002/ccd.28072

Background Clinical outcomes with respect to the evolution of comorbidity burden in national cohorts of patients undergoing PCI have not been reported. Objectives We sought to explore the association between comorbidity burden and periprocedural... Read More about The influence of Elixhauser comorbidity index on percutaneous coronary intervention outcomes.

Percutaneous Coronary Intervention in Cancer Patients: A Report of the Prevalence and Outcomes in the United States (2019)
Journal Article
Potts, J., Lopez Mattei, J., Martinez, S., Fischman, D., Mamas, M., Iliescu, C., …Rashid, M. (2019). Percutaneous Coronary Intervention in Cancer Patients: A Report of the Prevalence and Outcomes in the United States. European Heart Journal, 1790-+. https://doi.org/10.1093/eurheartj/ehy769

This study aims to examine the temporal trends and outcomes in patients who undergo percutaneous coronary intervention (PCI) with a previous or current diagnosis of cancer, according to cancer type and the presence of metastases. Methods and resul... Read More about Percutaneous Coronary Intervention in Cancer Patients: A Report of the Prevalence and Outcomes in the United States.

Temporal trends and predictors of time to coronary angiography following non-ST-elevation acute coronary syndrome in the USA (2019)
Journal Article
Fischman, D., Martinez, S., Potts, J., Mohamed, M., Kwok, C., Capers, Q., …Mamas, M. (2019). Temporal trends and predictors of time to coronary angiography following non-ST-elevation acute coronary syndrome in the USA. Coronary Artery Disease, 159-170. https://doi.org/10.1097/MCA.0000000000000693

OBJECTIVE: This study aims to investigate the temporal trends in utilization of invasive coronary angiography (CA) at different time points and changing profiles of patients undergoing CA following non-ST-elevation acute coronary syndrome (NSTEACS)... Read More about Temporal trends and predictors of time to coronary angiography following non-ST-elevation acute coronary syndrome in the USA.

VARIATIONS IN UTILIZATION OF INVASIVE CARDIAC PROCEDURES ACCORDING TO HOSPITAL CARDIAC FACILITIES STATUS IN MANAGEMENT OF NON-ST ELEVATION ACUTE MYOCARDIAL INFARCTION IN THE UNITED KINGDOM (2019)
Journal Article
Rashid, M., Kontopantelis, E., Kinnaird, T., Curzen, N., Gale, C., Mohamed, M., …Mamas, M. A. (2019). VARIATIONS IN UTILIZATION OF INVASIVE CARDIAC PROCEDURES ACCORDING TO HOSPITAL CARDIAC FACILITIES STATUS IN MANAGEMENT OF NON-ST ELEVATION ACUTE MYOCARDIAL INFARCTION IN THE UNITED KINGDOM. Journal of the American College of Cardiology, 73(9), 125. https://doi.org/10.1016/s0735-1097%2819%2930733-8

Incidence and prognostic impact of post discharge bleeding post acute coronary syndrome within an outpatient setting: a systematic review (2019)
Journal Article
Ismail, N., Jordan, K., Rao, S., Kinnaird, T., Potts, J., Kadam, U., & Mamas, M. (2019). Incidence and prognostic impact of post discharge bleeding post acute coronary syndrome within an outpatient setting: a systematic review. BMJ Open, 9(2), Article e023337. https://doi.org/10.1136/bmjopen-2018-023337

Objective The primary objective was to determine the incidence of bleeding events post acute coronary syndrome (ACS) following hospital discharge. The secondary objective was to determine the prognostic impact of bleeding on mortality, major adverse... Read More about Incidence and prognostic impact of post discharge bleeding post acute coronary syndrome within an outpatient setting: a systematic review.

Temporal trends and inequalities in coronary angiography utilization in the management of non-ST-Elevation acute coronary syndromes in the U.S. (2019)
Journal Article
Savage, M., Rashid, M., Fischman, D., Gulati, M., Tamman, K., Potts, J., …Mamas, M. (2019). Temporal trends and inequalities in coronary angiography utilization in the management of non-ST-Elevation acute coronary syndromes in the U.S. Scientific reports, https://doi.org/10.1038/s41598-018-36504-y

Coronary angiography (CA) is the basis of an invasive management strategy in non-ST elevation acute coronary syndromes (NSTEACS). There are limited contemporary data on national temporal trends in utilization of CA in different patient subgroups. We... Read More about Temporal trends and inequalities in coronary angiography utilization in the management of non-ST-Elevation acute coronary syndromes in the U.S..

Relation of Length of Stay to Unplanned Readmissions For Patients Who Undergo Elective Percutaneous Coronary Intervention (2019)
Journal Article
Gunning, M., Nolan, J., Kontopantelis, E., Bertrand, O., Kwok, C., Rao, S., …Mamas, M. (2019). Relation of Length of Stay to Unplanned Readmissions For Patients Who Undergo Elective Percutaneous Coronary Intervention. The American Journal of Cardiology, 123(1), 33-43. https://doi.org/10.1016/j.amjcard.2018.09.028

The cost of inpatient PCI procedure is related to LOS. It is unknown how LOS may be associated with readmission rates and costs of index PCI and readmissions in elective PCI. This study aims to evaluate rates, predictors, causes and costs associated... Read More about Relation of Length of Stay to Unplanned Readmissions For Patients Who Undergo Elective Percutaneous Coronary Intervention.

Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States (2018)
Journal Article
Ensor, J., Burke, D., Kwok, C., Riley, R., Holmvang, L., Mamas, M., …Rashid, M. (2018). Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States. PloS one, https://doi.org/10.1371/journal.pone.0203325

Background Prior studies have reported inconsistencies in the baseline risk profile, comorbidity burden and their association with clinical outcomes in women compared to men. More importantly, there is limited data around the sex differences and how... Read More about Persistent sex disparities in clinical outcomes with percutaneous coronary intervention: Insights from 6.6 million PCI precedures in the United States.

5258Trends and outcomes of use of coronary angiography in management of non-ST-Elevation acute coronary syndromes (NSTEACS), a population based cohort study (2018)
Journal Article
Rashid, M., Potts, J., Kwok, C., Mohammed, M., Shoaib, A., Esnsor, J., …Mamas, M. (2018). 5258Trends and outcomes of use of coronary angiography in management of non-ST-Elevation acute coronary syndromes (NSTEACS), a population based cohort study. European Heart Journal, 39(suppl_1), https://doi.org/10.1093/eurheartj/ehy566.5258

Background: Non-ST-elevation acute coronary syndromes (NSTEACS) remains most vulnerable phenotype of acute myocardial infarction despite significant improvements in treatment and provision of guideline-recommended care. Coronary angiography (CA) is t... Read More about 5258Trends and outcomes of use of coronary angiography in management of non-ST-Elevation acute coronary syndromes (NSTEACS), a population based cohort study.

Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). (2018)
Journal Article
Kwok, C., Mamas, M., Martinez, S., Pancholy, S., Ahmed, W., Al-Shaibi, K., …Curzen, N. (2018). Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database). Scientific reports, 11156 -?. https://doi.org/10.1038/s41598-018-29303-y

It is unclear how comorbidity influences rates and causes of unplanned readmissions following percutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database who were admitted to hospital between 2010 and 2014. T... Read More about Effect of Comorbidity On Unplanned Readmissions After Percutaneous Coronary Intervention (From The Nationwide Readmission Database)..

Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States (2018)
Journal Article
Al Shaibi, K., Gulati, R., Bell, M., Anderson, V., Potts, J., Rashid, M., …Kwok, C. (2018). Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States. JACC. Cardiovascular interventions, 1354-1364. https://doi.org/10.1016/j.jcin.2018.03.049

Discharge against medical advice (DAMA) in the context of PCI has not been described in the literature. Among the 2,021,104 patients, the proportion of patients who DAMA was 0.5% (n=10,049). Important predictors of DAMA included diagnosis of acute my... Read More about Discharge Against Medical Advice After Percutaneous Coronary Intervention in the United States.

Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database) (2018)
Journal Article
Martinez, S., Rao, S., Gilchrist, I., Kwok, C., Al Ayoubi, F., Myint, P., …Kontopantelis, E. (2018). Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database). American Journal of Cardiology, 220-228. https://doi.org/10.1016/j.amjcard.2018.03.367

It is unclear how age affects rates and causes of unplanned early readmissions after per cutaneous coronary intervention (PCI). We analyzed patients in the Nationwide Readmission Database in the United States from 2010 to 2014 and examined the impact... Read More about Relation Between Age and Unplanned Readmissions After Percutaneous Coronary Intervention (Findings From The Nationwide Readmission Database).

Temporal Changes in Comorbidity Burden in Patients Having Percutaneous Coronary Intervention and Impact on Prognosis (2018)
Journal Article
Potts, J., Kwok, C., Ensor, J., Rashid, M., Kadam, U., Kinnaird, T., …Mamas, M. (2018). Temporal Changes in Comorbidity Burden in Patients Having Percutaneous Coronary Intervention and Impact on Prognosis. American Journal of Cardiology, 122(5), 712-722. https://doi.org/10.1016/j.amjcard.2018.05.003

This study aims to evaluate the impact of comorbidity burden on outcomes among patients who undergo percutaneous coronary intervention (PCI). We used the Nationwide Inpatient Sample to identify all PCI procedures undertaken in the United States betwe... Read More about Temporal Changes in Comorbidity Burden in Patients Having Percutaneous Coronary Intervention and Impact on Prognosis.

Incidence, determinants and outcomes of left and right radial access use in patients undergoing percutaneous coronary intervention in the United Kingdom, a national perspective using the British Cardiovascular Intervention Society (BCIS) dataset (2018)
Journal Article
de Belder, M., Nolan, J., Mamas, M., Kinnaird, T., Ludman, P., Potts, J., …Rashid, M. (2018). Incidence, determinants and outcomes of left and right radial access use in patients undergoing percutaneous coronary intervention in the United Kingdom, a national perspective using the British Cardiovascular Intervention Society (BCIS) dataset. JACC. Cardiovascular interventions, 11(11), 1021-1033. https://doi.org/10.1016/j.jcin.2018.01.252

Objectives The authors sought to determine the relationships between left radial access (LRA) or right radial access (RRA) and clinical outcomes using the British Cardiovascular Intervention Society (BCIS) database. Background LRA has been shown... Read More about Incidence, determinants and outcomes of left and right radial access use in patients undergoing percutaneous coronary intervention in the United Kingdom, a national perspective using the British Cardiovascular Intervention Society (BCIS) dataset.

Burden of 30-day readmissions after PCI in 824,747 patients in the USA: predictors, causes and cost. Insights from the Nationwide Readmission Database (2018)
Journal Article
Rashid, M., Curzen, N., Nolan, J., Bagur, R., Mamas, M., Potts, J., …Kwok, C. (2018). Burden of 30-day readmissions after PCI in 824,747 patients in the USA: predictors, causes and cost. Insights from the Nationwide Readmission Database. JACC. Cardiovascular interventions, 655-674. https://doi.org/10.1016/j.jcin.2018.01.248

Objectives This study aimed to examine the 30-day unplanned readmissions rate, predictors of readmission, causes of readmissions, and clinical impact of readmissions after percutaneous coronary intervention (PCI). Background Unplanned rehospital... Read More about Burden of 30-day readmissions after PCI in 824,747 patients in the USA: predictors, causes and cost. Insights from the Nationwide Readmission Database.

Retroperitoneal Hemorrhage After Percutaneous Coronary Intervention: Incidence, Determinants, and Outcomes as Recorded by the British Cardiovascular Intervention Society. (2018)
Journal Article
Kontopantelis, E., Kinnaird, T., Potts, J., Rashid, M., Shoaib, A., Nolan, J., …Cardiovascular Intervention Society (BCIS) and National, B. (2018). Retroperitoneal Hemorrhage After Percutaneous Coronary Intervention: Incidence, Determinants, and Outcomes as Recorded by the British Cardiovascular Intervention Society. Circulation: Cardiovascular Interventions, 11(2), Article e005866. https://doi.org/10.1161/CIRCINTERVENTIONS.117.005866

BACKGROUND: Retroperitoneal hemorrhage (RH) is a rare bleeding complication of percutaneous coronary intervention, which can result as a consequence of femoral access or can occur spontaneously. This study aims to evaluate temporal changes in RH, its... Read More about Retroperitoneal Hemorrhage After Percutaneous Coronary Intervention: Incidence, Determinants, and Outcomes as Recorded by the British Cardiovascular Intervention Society..

Do quality indicators for general practice teaching practices predict good outcomes for students? (2016)
Journal Article
Bartlett, M., Potts, J., & McKinley, R. (2016). Do quality indicators for general practice teaching practices predict good outcomes for students?. Education for Primary Care, 271-279. https://doi.org/10.1080/14739879.2016.1175913

Keele medical students spend 113 days in general practices over our five-year programme. We collect practice data thought to indicate good quality teaching. We explored the relationships between these data and two outcomes for students; Objective Str... Read More about Do quality indicators for general practice teaching practices predict good outcomes for students?.

The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis (2015)
Journal Article
Potts, J., Gray, L., Brady, E., Khunti, K., Davies, M., & Bodicoat, D. (2015). The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis. PloS one, https://doi.org/10.1371/journal.pone.0126769

Aims To determine the effects of glucagon-like peptide-1 receptor agonists compared with placebo and other anti-diabetic agents on weight loss in overweight or obese patients with type 2 diabetes mellitus. Methods Electronic searches were conduc... Read More about The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis.