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Outputs (40)

Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers (2024)
Journal Article

Background Conducting effective and translational research can be challenging and few trials undertake formal reflection exercises and disseminate learnings from them. Following completion of our multicentre randomised controlled trial, which was im... Read More about Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers.

Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. (2023)
Journal Article

Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks. Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP)... Read More about Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol..

Investigating the usefulness of Automated Check-in Data Collection in general practice (AC DC Study): a multicentre, cross-sectional study in England. (2023)
Journal Article

Objectives: To investigate the usefulness of using automated appointment check-in screens to collect brief research data from patients, prior to their general practice consultation. Design: A descriptive, cross-sectional study. Setting: Nine ge... Read More about Investigating the usefulness of Automated Check-in Data Collection in general practice (AC DC Study): a multicentre, cross-sectional study in England..

Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care (2022)
Journal Article

Objective To describe factors associated with change in health-related quality of life (HRQOL) in people living with gout in primary care. Methods In a UK prospective cohort study, adults with a diagnosis of gout registered with 20 general practices... Read More about Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care.

The impact of polymyalgia rheumatica on intimate sexual relationships: findings from the PMR Cohort Study (2022)
Journal Article

Objectives To determine the impact of polymyalgia rheumatica (PMR) on intimate and sexual relationships over time. Methods The PMR Cohort study (UKCRN ID16477) is a longitudinal study of patients with incident PMR in English primary care. Participant... Read More about The impact of polymyalgia rheumatica on intimate sexual relationships: findings from the PMR Cohort Study.

Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial. (2021)
Journal Article

Background: Multimorbidity is increasingly the norm; however, primary care remains focused on single diseases. Osteoarthritis, anxiety, and depression are frequently comorbid with other long-term conditions (LTCs), but rarely prioritized by clinician... Read More about Integrating case-finding and initial management for osteoarthritis, anxiety, and depression into primary care long-term condition reviews: results from the ENHANCE pilot trial..

Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial (2021)
Journal Article

Plantar heel pain (PHP) is common and impacts negatively on physical function and quality of life. Initial treatment usually comprises analgesia and self-management advice (SMA), with referral to a physiotherapist or podiatrist recommended only when... Read More about Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial.

Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial (2020)
Journal Article

Atrial fibrillation (AF) is associated with an increased risk of stroke, enhanced stroke severity, and other comorbidities. However, AF is often asymptomatic, and frequently remains undiagnosed until complications occur. Current screening approaches... Read More about Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial.

P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care (2020)
Journal Article

Background Gout affects 2.5% of adults in the UK but is often poorly managed. It can impair health-related quality of life (HRQOL), yet little is known about which people with gout are at risk of worse outcomes. We investigated factors associated wi... Read More about P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care.

Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study (2019)
Journal Article

Objectives. To investigate potential subgroups of primary care diagnosed patients with polymyalgia rheumatica (PMR) based on self-reported pain and stiffness severity over time. Methods. 652 people with an incident PMR diagnosis were recruited fro... Read More about Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study.

Health informatics (HI) innovations in randomised trials and clinical cohorts - Identification, screening, stratified care and data collection during primary care consultations (2019)
Presentation / Conference

Introduction: Recruitment and retention of participants remain the main challenges for clinical research, particularly for primary care studies undertaken at point-of-care where consultation time is pressured. The Health Informatics (HI) team at Keel... Read More about Health informatics (HI) innovations in randomised trials and clinical cohorts - Identification, screening, stratified care and data collection during primary care consultations.

Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey (2019)
Journal Article

Objectives: To describe the prevalence of self-reported inflammatory joint symptoms, such as joint pain, stiffness and swelling in UK primary care patients consulting for both musculoskeletal (MSK) and non-musculoskeletal (non-MSK) complaints. Met... Read More about Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey.

Challenges of diagnosing and managing polymyalgia rheumatica: a multi-methods study in UK general practice (2018)
Journal Article

BACKGROUND: Polymyalgia rheumatica (PMR) is one of the most common inflammatory arthritic disorders seen in older individuals. Most patients with PMR are diagnosed and managed exclusively in general practice, yet primary care-focused research is lack... Read More about Challenges of diagnosing and managing polymyalgia rheumatica: a multi-methods study in UK general practice.

Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669). (2018)
Journal Article

Musculoskeletal pain is a common cause of work absence and early intervention is advocated to prevent the adverse health and economic consequences of longer-term absence. This cluster randomised controlled trial investigated the effect of introducing... Read More about Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669)..

Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial (2017)
Journal Article

Background Co-morbid osteoarthritis (OA), anxiety and depression are undermanaged in primary care yet have significant impact on pain, disability and outcomes of other long-term conditions (LTCs). Objectives To test the feasibility and acceptabili... Read More about Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial.

The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial (2017)
Conference Proceeding

Background Frequent data collection is desirable in randomised controlled trials (RCTs) where time‐to‐event is the primary outcome, in order to accurately capture the event of interest with reduced risk of recall bias. However, an inevitable problem... Read More about The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial.

The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial (2017)
Presentation / Conference

Background Frequent data collection is desirable in randomised controlled trials (RCTs) where time-to-event is the primary outcome, in order to accurately capture the event of interest with reduced risk of recall bias. However, an inevitable problem... Read More about The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial.

Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study. (2016)
Journal Article

BACKGROUND: The aim was to characterise the sociodemographic, general health and polymyalgia rheumatica (PMR)-specific features of participants in a large inception cohort of patients with PMR diagnosed in UK primary care. METHODS: Patients (n?=?739)... Read More about Characterising those with incident polymyalgia rheumatica in primary care: results from the PMR Cohort Study..

Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial (2015)
Journal Article

Background: Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused o... Read More about Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial.