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Edward Roddy's Outputs (24)

Prevalence of foot pain across an international consortium of population based cohorts. (2018)
Journal Article
Gates, L. S., Arden, N. K., Hannan, M. T., Roddy, E., Gill, T. K., Hill, C. L., …Golightly, Y. M. (2019). Prevalence of foot pain across an international consortium of population based cohorts. Arthritis Care and Research, 71(5), 661-670. https://doi.org/10.1002/acr.23829

OBJECTIVE:
Despite the potential burden of foot pain, some of the most fundamental epidemiological questions surrounding the foot remain poorly explored. The prevalence of foot pain has proved difficult to compare across existing studies due to var... Read More about Prevalence of foot pain across an international consortium of population based cohorts..

Gout severity, socioeconomic status and work absence: a cross-sectional study in primary care (2018)
Journal Article
Mallen, Roddy, & Muller. (2018). Gout severity, socioeconomic status and work absence: a cross-sectional study in primary care. Arthritis Care and Research, 1822-1828. https://doi.org/10.1002/acr.23562

Objective
To examine the association between gout severity and socioeconomic status (SES) and gout severity and work absence.

Methods
Postal questionnaires were sent to adult patients who were registered with 20 general practices and who had co... Read More about Gout severity, socioeconomic status and work absence: a cross-sectional study in primary care.

Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study (2018)
Journal Article
Mallen, Roddy, Belcher, Clarson, & Muller. (2018). Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study. Arthritis Research and Therapy, 20, Article 243. https://doi.org/10.1186/s13075-018-1746-1

BACKGROUND: An association between gout and renal disease is well-recognised but few studies have examined whether gout is a risk factor for subsequent chronic kidney disease (CKD). Additionally, the impact of urate-lowering therapy (ULT) on developm... Read More about Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study.

Efficacy of Shoe-Stiffening Inserts for First Metatarsophalangeal Joint Osteoarthritis: Preliminary Findings from the Simple Randomised Controlled Trial (2018)
Presentation / Conference
Munteanu, S., Landorf, K., McClelland, J., Roddy, E., Cicuttini, F., Shiell, A., …Menz, H. B. (2018, October). Efficacy of Shoe-Stiffening Inserts for First Metatarsophalangeal Joint Osteoarthritis: Preliminary Findings from the Simple Randomised Controlled Trial

Background/Purpose: This trial assessed the efficacy of shoe-stiffening inserts for reducing pain associated with first metatarsophalangeal joint (MTPJ) osteoarthritis (OA).

Methods: One hundred participants (45 men 55 women, mean age 57.5, SD 10.... Read More about Efficacy of Shoe-Stiffening Inserts for First Metatarsophalangeal Joint Osteoarthritis: Preliminary Findings from the Simple Randomised Controlled Trial.

Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study (2018)
Presentation / Conference
Crowley, L., Abdul Sultan, A., Roddy, E., Mallen, C., Protheroe, J., & Clarson, L. (2018, October). Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study. Poster presented at 2018 ACR/ARHP Annual Meeting

Background/Purpose: Evidence is conflicting concerning dementia risk in gout patients, with hyperuricaemia proposed to exert a neuroprotective effect. Serum urate (sUA) targets guiding urate-lowering therapies (ULT) are poorly evidenced-based and th... Read More about Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study.

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. (2018)
Journal Article
Chesterton, L. S., Blagojevic-Bucknall, M., Burton, C., Dziedzic, K. S., Davenport, G., Jowett, S. M., …Roddy, E. (2018). The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. The Lancet, 392(10156), 1423 - 1433. https://doi.org/10.1016/s0140-6736%2818%2931572-1

Background
To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splint... Read More about The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial..

Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain (2018)
Journal Article
Menz, H. B., Thomas, M., Marshall, M., Rathod-Mistry, T., Hall, A., Chesterton, L. S., …Roddy, E. (2019). Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain. Rheumatology, 58(2), 237-245. https://doi.org/10.1093/rheumatology/key266

Objectives
To examine associations between plantar calcaneal spurs, plantar fascia thickening and plantar heel pain (PHP), and to determine whether tenderness on palpation of the heel differentiates between these presentations.

Methods
Adults... Read More about Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain.

The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study (2018)
Journal Article
Blagojevic‐Bucknall, M., Mallen, C., Muller, S., Hayward, R., West, S., Choi, H., & Roddy, E. (2019). The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study. Arthritis & Rheumatology, 71(1), 154-160. https://doi.org/10.1002/art.40662

Objective
Obstructive sleep apnea (OSA) is associated with a range of serious comorbidities. This study investigates whether people with OSA are more likely to develop gout than those without OSA in both short and long term.

Methods A matched ret... Read More about The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study.

Comorbidity clusters in people with gout: an observational cohort study with linked medical record review (2018)
Journal Article
Mallen, Roddy, Bucknall, & Hider. (2018). Comorbidity clusters in people with gout: an observational cohort study with linked medical record review. Rheumatology, 1358-1363. https://doi.org/10.1002/acr.23562

Objective. To investigate how comorbid conditions cluster in patients with gout in a UK primary care population.

Methods. A cross-sectional study was performed using baseline data from a primary-care-based prospective observational cohort of peop... Read More about Comorbidity clusters in people with gout: an observational cohort study with linked medical record review.

Health-related quality of life in gout in primary care: baseline findings from a cohort study (2018)
Journal Article
Roddy, Mallen, Bucknall, Muller, & Hider. (2018). Health-related quality of life in gout in primary care: baseline findings from a cohort study. Seminars in Arthritis and Rheumatism, 61-69. https://doi.org/10.1016/j.semarthrit.2017.12.005

Objectives: To examine gout-related, comorbid, and sociodemographic characteristics associated with generic and disease-specific health-related quality of life (HRQOL) in gout.

Methods: Adults with gout from 20 general practices were mailed a que... Read More about Health-related quality of life in gout in primary care: baseline findings from a cohort study.

Gout: Is there a role in management for the general practice nurse? (2018)
Journal Article
Finney, A., Viggars, R., & Roddy, E. (2018). Gout: Is there a role in management for the general practice nurse?. Practice Nurse,

This chapter focuses on gout, the most prevalent form of inflammatory arthritis. This chapter informs nurses of the signs, symptoms and treatments for gout. Current guideline recommendations are defined, and the educational needs for healthcare profe... Read More about Gout: Is there a role in management for the general practice nurse?.

A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol (2018)
Journal Article
Paskins, Z., Hughes, G., Myers, H., Hughes, E., Hennings, S., Cherrington, A., …Roddy, E. (2018). A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol. BMC Musculoskeletal Disorders, 19, Article 218. https://doi.org/10.1186/s12891-018-2153-0

BACKGROUND: Evidence on the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis is limited and conflicting. The primary objective of the Hip Injection Trial (HIT) is to compare pain intensity over 6 months, in people with... Read More about A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol.

Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies (2018)
Journal Article
Evans, P. L., Prior, J. A., Belcher, J., Mallen, C., Hay, C. A., & Roddy, E. (2018). Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies. Arthritis Research and Therapy, 20, Article 136. https://doi.org/10.1186/s13075-018-1612-1

BACKGROUND: Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hypertension and diuretic use. METHOD... Read More about Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.

Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Muller, Hider, Helliwell, & Paskins. (2018). Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study. Osteoporosis International, 1659-1664. https://doi.org/10.1007/s00198-018-4491-z

This study aimed to examine fracture risk in patients with late-onset psoriasis. A cohort study was conducted using primary care records from the Clinical Practice Research Datalink. Psoriasis patients had a 10% increased risk of fracture compared to... Read More about Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study.

Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis (2018)
Journal Article
Babatunde, Van Der Windt, Roddy, & Thomas. (2018). Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis. British Journal of Sports Medicine, 53(3), 1-14. https://doi.org/10.1136/bjsports-2017-098998

Objective
To evaluate the comparative effectiveness of current treatment options for plantar heel pain (PHP).

Design
Systematic review and network meta-analysis (NMA).

Data sources
Medline, EMBASE, CINAHL, AMED, PEDro, Cochrane Database, Web... Read More about Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis.

Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis (2018)
Journal Article
Babatunde, O., Legha, A., Littlewood, C., Chesterton, L. S., Thomas, M. J., B Menz, H., …Roddy, E. (2018). Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis. British Journal of Sports Medicine, 53(3), https://doi.org/10.1136/bjsports-2017-098998

Objective
To evaluate the comparative effectiveness of current treatment options for plantar heel pain (PHP).

Design
Systematic review and network meta-analysis (NMA).

Data Sources
Medline, EMBASE, CINAHL, AMED, PEDro, Cochrane Database, We... Read More about Comparative Effectiveness of Treatment Options for Plantar Heel Pain: A Systematic Review with Network Meta-Analysis.

Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout (2018)
Journal Article
Bursill, D., Taylor, W. J., Terkeltaub, R., Kuwabara, M., Merriman, T. R., Grainger, R., …Dalbeth, N. (2019). Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout. Arthritis Care and Research, 71(3), 427-434. https://doi.org/10.1002/acr.23607

OBJECTIVE:
The language currently used to describe gout lacks standardisation. The aim of this project was to develop a consensus statement on the labels and definitions used to describe the basic disease elements of gout.

METHODS: Experts in g... Read More about Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout.

Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy (2018)
Journal Article
Paskins, Mallen, Bucknall, Hider, Muller, Helliwell, & Roddy. (2018). Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy. Canadian Medical Association Journal, E581 -E587. https://doi.org/10.1503/cmaj.170806

BACKGROUND: Previous studies that quantified the risk of fracture among patients with gout and assessed the potential effect of urate-lowering therapy have provided conflicting results. Our study aims to provide better estimates of risk by minimizing... Read More about Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy.

Management of gout by UK rheumatologists: a British Society for Rheumatology national audit (2018)
Journal Article
Roddy. (2018). Management of gout by UK rheumatologists: a British Society for Rheumatology national audit. Rheumatology, 826-830. https://doi.org/10.1093/rheumatology/kex521

Objectives
To assess the concordance of gout management by UK rheumatologists with evidence-based best-practice recommendations.

Methods
Data were collected on patients newly referred to UK rheumatology out-patient departments over an 8-week per... Read More about Management of gout by UK rheumatologists: a British Society for Rheumatology national audit.

Population Prevalence and Distribution of Ankle Pain and Symptomatic Radiographic Ankle Osteoarthritis in Community Dwelling Older Adults: A Systematic Review and Cross-Sectional Study (2018)
Journal Article
Murray, C., Marshall, M., Rathod, T., Bowen, C. J., Menz, H. B., & Roddy, E. (2018). Population Prevalence and Distribution of Ankle Pain and Symptomatic Radiographic Ankle Osteoarthritis in Community Dwelling Older Adults: A Systematic Review and Cross-Sectional Study. PloS one, 13(4), Article e0193662. https://doi.org/10.1371/journal.pone.0193662

Objectives
To identify by systematic review published prevalence estimates of radiographic ankle osteoarthritis (OA) and to subsequently estimate the prevalence of ankle pain and symptomatic, radiographic ankle OA within community-dwelling older adu... Read More about Population Prevalence and Distribution of Ankle Pain and Symptomatic Radiographic Ankle Osteoarthritis in Community Dwelling Older Adults: A Systematic Review and Cross-Sectional Study.

Foot osteoarthritis: latest evidence and developments (2018)
Journal Article
Roddy, E., & Menz, H. B. (2018). Foot osteoarthritis: latest evidence and developments. Therapeutic Advances in Musculoskeletal Disease, 10(4), 91-103. https://doi.org/10.1177/1759720x17753337

Foot osteoarthritis (OA) is a common problem in older adults yet is under-researched compared to knee or hand OA. Most existing studies focus on the first metatarsophalangeal joint, with evidence relating to midfoot OA being particularly sparse. Symp... Read More about Foot osteoarthritis: latest evidence and developments.

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background
Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.