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Edward Roddy's Outputs (24)

Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care (2022)
Journal Article
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., Lawton, S. A., Mallen, C. D., Muller, S., Rome, K., & Roddy, E. (2022). Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care. Rheumatology, 62(8), 2748-2756. https://doi.org/10.1093/rheumatology/keac706

Objective To describe factors associated with change in health-related quality of life (HRQOL) in people living with gout in primary care. Methods In a UK prospective cohort study, adults with a diagnosis of gout registered with 20 general practices... Read More about Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care.

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Presentation / Conference Contribution
Merriman, T., Matsuo, H., Takei, R., Leask, M., Topless, R., Shirai, Y., Li, Z., Cadzow, M., Reynolds, R., Saag, K., Fadason, T., O'Sullivan, J., Dalbeth, N., Stamp, L., Abhishek, A., Doherty, M., Roddy, E., Jacobsson, L., Kapetanovic, M., Andrès, M., …Major, T. (2022, November). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Presented at ACR Convergence 2022

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (≤13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.

Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. (2022)
Journal Article
Roddy, E., Russell, M. D., Rutherford, A. I., Ellis, B., Norton, S., Douiri, A., Gulliford, M. C., Cope, A. P., & Galloway, J. B. (2023). Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. Rheumatology, 62(7), 2426-2434. https://doi.org/10.1093/rheumatology/keac638

Objective To investigate associations between treat-to-target urate-lowering therapy (ULT) and hospitalizations for gout. Methods Using linked Clinical Practice Research Datalink and NHS Digital Hospital Episode Statistics data, we described the inci... Read More about Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England..

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids (2022)
Journal Article
Russell, M. D., Dey, M., Flint, J., Davie, P., Allen, A., Crossley, A., Frishman, M., Gayed, M., Hodson, K., Khamashta, M., Moore, L., Panchal, S., Piper, M., Reid, C., Saxby, K., Schreiber, K., Senvar, N., Tosounidou, S., van de Venne, M., Warburton, L., …Williams, E. (2022). British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology, 62(4), e48-e88. https://doi.org/10.1093/rheumatology/keac551

Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. (2022)
Journal Article
Roddy, E. (2022). Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. Arthritis and Rheumatology, 75(5), 816-825. https://doi.org/10.1002/art.42393

OBJECTIVE: To determine whether a gout polygenic risk score (PRS) associates with age at gout onset and tophaceous disease in European (EUR), East Polynesian (EP), and West Polynesian (WP) men/women with gout.

METHODS: A 19-variant gout PRS was p... Read More about Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout..

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Journal Article
Roddy. (2022). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Arthritis and Rheumatology, 3338 - 3341

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (=13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.

Large variation in participant eligibility criteria used in plantar heel pain research studies - a systematic review. (2022)
Journal Article
Riel, H., Plinsinga, M. L., Delahunt, E., Jensen, M. B., Landorf, K. B., van Middelkoop, M., Roddy, E., Rathleff, M. S., Vicenzino, B., & Olesen, J. L. (2022). Large variation in participant eligibility criteria used in plantar heel pain research studies - a systematic review. Journal of Foot and Ankle Research, 15(1), Article 69. https://doi.org/10.1186/s13047-022-00573-0

INTRODUCTION: Variable eligibility criteria across studies on plantar heel pain may result in compromising the generalisability of meta-analyses when heterogeneity is not accounted for. We aimed to explore: (i) heterogeneity of participant eligibilit... Read More about Large variation in participant eligibility criteria used in plantar heel pain research studies - a systematic review..

Incidence and Progression of Hallux Valgus: A Prospective Cohort Study (2022)
Journal Article
Menz, H. B., Marshall, M., Thomas, M. J., Rathod‐Mistry, T., Peat, G. M., & Roddy, E. (2023). Incidence and Progression of Hallux Valgus: A Prospective Cohort Study. Arthritis Care and Research, 75(1), 166-173. https://doi.org/10.1002/acr.24754

OBJECTIVE: Hallux valgus is a common and disabling condition. The objective of this study was to identify factors associated with hallux valgus incidence and progression. METHODS: Participants were from a population-based prospective cohort study, th... Read More about Incidence and Progression of Hallux Valgus: A Prospective Cohort Study.

Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study (2022)
Presentation / Conference Contribution
Rathod-Mistry, T., Roddy, E., Jordan, K., Mallen, C., & Blagojevic-Bucknall, M. (2022, August). Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study

Background: Allopurinol is intended to be taken for life in the treatment of gout. In UK primary care, treatment is suboptimal with up to 30% of indicated patients being treated within five years of diagnosis and once prescribed allopurinol, treatmen... Read More about Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study.

Effects of Shoe-Stiffening Inserts on Lower Limb Kinematics in Individuals with First Metatarsophalangeal Joint Osteoarthritis. (2022)
Journal Article
Roddy, E., McClelland, J. A., Allan, J. J., Auhl, M., Buldt, A. K., Landorf, K. B., Cicuttini, F. M., Menz, H. B., & Munteanu, S. E. (2022). Effects of Shoe-Stiffening Inserts on Lower Limb Kinematics in Individuals with First Metatarsophalangeal Joint Osteoarthritis. Arthritis Care and Research, 74(11), 1849-1856. https://doi.org/10.1002/acr.24647

OBJECTIVE: To examine the effects of shoe-stiffening inserts on lower limb kinematics in individuals with first metatarsophalangeal (MTP) joint osteoarthritis (OA).

METHODS: Forty-eight individuals with radiographically confirmed first MTP joint... Read More about Effects of Shoe-Stiffening Inserts on Lower Limb Kinematics in Individuals with First Metatarsophalangeal Joint Osteoarthritis..

Footwear, foot orthoses and strengthening exercises for the non-surgical management of hallux valgus: protocol for a randomised pilot and feasibility trial (2022)
Journal Article
Roddy, Menz, H. B., Lim, P. Q., Hurn, S. E., Mickle, K. J., Buldt, A. K., Cotchett, M. P., Roddy, E., Wluka, A. E., Erbas, B., & Munteanu, S. E. (2022). Footwear, foot orthoses and strengthening exercises for the non-surgical management of hallux valgus: protocol for a randomised pilot and feasibility trial. Journal of Foot and Ankle Research, 15(1), Article ARTN 45. https://doi.org/10.1186/s13047-022-00553-4

Background: Hallux valgus is a common and disabling condition. This randomised pilot and feasibility trial aims to determine the feasibility of conducting a fully-powered parallel group randomised trial to evaluate the effectiveness of a multifaceted... Read More about Footwear, foot orthoses and strengthening exercises for the non-surgical management of hallux valgus: protocol for a randomised pilot and feasibility trial.

NEUROPATHIC PAIN IN FIRST METATARSOPHALANGEAL JOINT OSTEOARTHRITIS: FREQUENCY AND ASSOCIATED FACTORS (2022)
Presentation / Conference
Roddy. (2022, May). NEUROPATHIC PAIN IN FIRST METATARSOPHALANGEAL JOINT OSTEOARTHRITIS: FREQUENCY AND ASSOCIATED FACTORS. Presented at Australian Rheumatology Association 62nd Annual Scientific Meeting, Sydney, Adelaide, Brisbane, Hobart, Melbourne, Australia and Auckland, New Zealand

Aim: To determine whether neuropathic pain is a feature of first metatarsophalangeal (MTP) joint osteoarthritis (OA). Method: Ninety-eight participants (54 women and 44 men, mean age 57.4?years, standard deviation 10.3) with symptomatic radiographic... Read More about NEUROPATHIC PAIN IN FIRST METATARSOPHALANGEAL JOINT OSTEOARTHRITIS: FREQUENCY AND ASSOCIATED FACTORS.

P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions (2022)
Journal Article
Roddy, Paskins, Hider, & Muller. (2022). P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.090

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>The COVID-19 pandemic led to an overnight shift in healthcare delivery and rapid uptake of digital technology. Such approaches risk digital exclusion for pe... Read More about P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions.

P145 Safety of colchicine or NSAID prophylaxis when initiating allopurinol for gout: propensity score-matched cohort studies (2022)
Presentation / Conference Contribution
Roddy, E., Bajpai, R., Forrester, H., Partington, R., Mallen, C. D., Clarson, L., Padmanabhan, N., Whittle, R., & Muller, S. P145 Safety of colchicine or NSAID prophylaxis when initiating allopurinol for gout: propensity score-matched cohort studies

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>Initiating urate-lowering therapy for gout commonly triggers a gout flare and hence co-prescription of colchicine or non-steroidal anti-inflammatory drug (N... Read More about P145 Safety of colchicine or NSAID prophylaxis when initiating allopurinol for gout: propensity score-matched cohort studies.

P182 Health literacy and gout characteristics in a primary care cohort (2022)
Presentation / Conference Contribution
Watson, L., Protheroe, J., Mallen, C., Muller, S., & Roddy, E. P182 Health literacy and gout characteristics in a primary care cohort

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>Gout is the most common inflammatory arthritis, affecting 2.5% of the UK population. It is often suboptimally managed, despite the availability of effective... Read More about P182 Health literacy and gout characteristics in a primary care cohort.

P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey (2022)
Journal Article
Roddy, Hider, Muller, & Paskins. (2022). P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.063

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>Concerns about the risk of COVID-19 infection led to guidelines advocating shielding for many people with inflammatory conditions. We aimed to assess the im... Read More about P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey.