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Danielle Van Der Windt's Outputs (211)

Risk factors for shoulder pain and stiffness in adults aged 44 and older: an 11-year longitudinal population-based study (2024)
Journal Article
Lahti, V., Ibounig, T., Rämö, L., Härkänen, T., Shiri, R., van der Windt, D., …Heliövaara, M. (2024). Risk factors for shoulder pain and stiffness in adults aged 44 and older: an 11-year longitudinal population-based study. Scandinavian Journal of Rheumatology, 1-7. https://doi.org/10.1080/03009742.2024.2420443

Objective
We conducted a longitudinal observational study over 11 years to identify the risk factors for developing shoulder pain, stiffness, or both.

Method
The study population (n = 1645) was identified from Health 2000 Survey, a nationally re... Read More about Risk factors for shoulder pain and stiffness in adults aged 44 and older: an 11-year longitudinal population-based study.

Personalised decision support in the management of patients with musculoskeletal pain in primary physiotherapy care: a cluster randomised controlled trial (the SupportPrim project) (2024)
Journal Article
Granviken, F., Meisingset, I., Bach, K., Bones, A. F., Simpson, M. R., Hill, J. C., …Vasseljen, O. (2024). Personalised decision support in the management of patients with musculoskeletal pain in primary physiotherapy care: a cluster randomised controlled trial (the SupportPrim project). PAIN, https://doi.org/10.1097/j.pain.0000000000003456

We developed the SupportPrim PT clinical decision support system (CDSS) using the artificial intelligence method case-based reasoning to support personalised musculoskeletal pain management. The aim of this study was to evaluate the effectiveness of... Read More about Personalised decision support in the management of patients with musculoskeletal pain in primary physiotherapy care: a cluster randomised controlled trial (the SupportPrim project).

Patient preferences for conservative treatment of shoulder pain: a discrete choice experiment (2024)
Journal Article
Versloot, A. H. C., Veldwijk, J., Ottenheijm, R. P. G., de Graaf, M., van der Windt, D. A., Koes, B. W., …Schiphof, D. (2024). Patient preferences for conservative treatment of shoulder pain: a discrete choice experiment. Family Practice, https://doi.org/10.1093/fampra/cmae050

Shoulder pain is common amongst adults, but little is known about patients' preferences. The aim of this study was to determine patients' preferences for treatment options offered for shoulder pain in primary care. A discrete choice experiment was us... Read More about Patient preferences for conservative treatment of shoulder pain: a discrete choice experiment.

Are patients with newly diagnosed frozen shoulder more likely to be diagnosed with type 2 diabetes? A cohort study in UK electronic health records (2024)
Journal Article
Dyer, B. P., Burton, C., Rathod‐Mistry, T., Blagojevic‐Bucknall, M., & van der Windt, D. A. (2024). Are patients with newly diagnosed frozen shoulder more likely to be diagnosed with type 2 diabetes? A cohort study in UK electronic health records. Diabetes, Obesity and Metabolism, https://doi.org/10.1111/dom.15965

Aim: To estimate the association between newly diagnosed frozen shoulder and a subsequent diagnosis of type 2 diabetes in primary care. Methods: We conducted an age‐, gender‐ and practice‐matched cohort study in UK primary care electronic medical rec... Read More about Are patients with newly diagnosed frozen shoulder more likely to be diagnosed with type 2 diabetes? A cohort study in UK electronic health records.

Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome (2024)
Journal Article
Hattle, M., Ensor, J., Scandrett, K., van Middelkoop, M., van der Windt, D. A., Holden, M. A., & Riley, R. D. (2024). Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1750

Individual participant data (IPD) meta‐analysis projects obtain, harmonise, and synthesise original data from multiple studies. Many IPD meta‐analyses of randomised trials are initiated to identify treatment effect modifiers at the individual level,... Read More about Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome.

Association of air pollution from a landfill site with primary care consultation (2024)
Working Paper
Jordan, K. P., Muller, S., Usman, M., Bailey, J., Burton, C., Lawton, S. A., …van der Windt, D. A. Association of air pollution from a landfill site with primary care consultation

Background Waste landfill sites are associated with gaseous emissions and this air pollution can cause unpleasant smells (“malodour”). This causes concerns about its impact on the health of the local population. This study assessed change in general... Read More about Association of air pollution from a landfill site with primary care consultation.

Development and initial evaluation of a clinical prediction model for risk of treatment resistance in first-episode psychosis: Schizophrenia Prediction of Resistance to Treatment (SPIRIT) (2024)
Journal Article
Farooq, S., Hattle, M., Kingstone, T., Ajnakina, O., Dazzan, P., Demjaha, A., …Riley, R. D. (2024). Development and initial evaluation of a clinical prediction model for risk of treatment resistance in first-episode psychosis: Schizophrenia Prediction of Resistance to Treatment (SPIRIT). British Journal of Psychiatry, 1-10. https://doi.org/10.1192/bjp.2024.101

Background
A clinical tool to estimate the risk of treatment-resistant schizophrenia (TRS) in people with first-episode psychosis (FEP) would inform early detection of TRS and overcome the delay of up to 5 years in starting TRS medication.

Aims... Read More about Development and initial evaluation of a clinical prediction model for risk of treatment resistance in first-episode psychosis: Schizophrenia Prediction of Resistance to Treatment (SPIRIT).

Diabetes, metabolic health, and the development of frozen shoulder: a cohort study in UK electronic health records (2024)
Working Paper
Dyer, B., Burton, C., Rathod-Mistry, T., Blagojevic-Bucknall, M., & van der Windt, D. Diabetes, metabolic health, and the development of frozen shoulder: a cohort study in UK electronic health records

Objective Estimate the effect of type 2 diabetes on the development of frozen shoulder and investigate whether the effect is mediated by other metabolic factors. Methods Primary care medical record-based cohort study containing 43,977 patients newly... Read More about Diabetes, metabolic health, and the development of frozen shoulder: a cohort study in UK electronic health records.

Stratified health care for low back pain using the STarT Back approach: Holy Grail or doomed to fail? (2024)
Journal Article
Croft, P., Hill, J. C., Foster, N. E., Dunn, K. M., & van der Windt, D. A. (2024). Stratified health care for low back pain using the STarT Back approach: Holy Grail or doomed to fail?. PAIN, https://doi.org/10.1097/j.pain.0000000000003319

There have been at least 7 separate randomised controlled trials published between 2011 and 2023 that have examined primary care for nonspecific low back pain informed by the STarT Back approach to stratified care based on risk prediction, compared w... Read More about Stratified health care for low back pain using the STarT Back approach: Holy Grail or doomed to fail?.

Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare (2024)
Journal Article
Archer, L., Peat, G., Snell, K. I. E., Hill, J. C., Dunn, K. M., Foster, N. E., …Wynne-Jones, G. (2024). Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10223-w

Purpose
To develop and validate prediction models for the risk of future work absence and level of presenteeism, in adults seeking primary healthcare with musculoskeletal disorders (MSD).

Methods
Six studies from the West-Midlands/Northwest regi... Read More about Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare.

Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review] (2024)
Journal Article
Twohig, H., Bajpai, R., Corp, N., Faux-Nightingale, A., Mallen, C., Robinson, T., …Burton, C. (2024). Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review]. NIHR Open Research, 4(22), https://doi.org/10.3310/nihropenres.13549.1

Background
Children and young people (CYP) may experience prolonged symptoms following COVID-19, commonly termed ‘Long-COVID’. The characteristics of Long-COVID in CYP are unclear, as are the sequalae of acute COVID-19. We aimed to systematically sy... Read More about Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review].

818 NEITHER ANALYSIS APPROACH NOR RISK OF BIAS EXPLAIN THE LIMITED OVERALL BENEFIT OF THERAPEUTIC EXERCISE FOR KNEE AND/OR HIP OSTEOARTHRITIS IN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS (2024)
Presentation / Conference
Runhaar, J., Holden, M., Hattle, M., Quicke, J., Healey, E. L., van der Windt, D., …Foster, N. (2024, April). 818 NEITHER ANALYSIS APPROACH NOR RISK OF BIAS EXPLAIN THE LIMITED OVERALL BENEFIT OF THERAPEUTIC EXERCISE FOR KNEE AND/OR HIP OSTEOARTHRITIS IN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults. (2024)
Journal Article
Archer, L., L, A., Relton, S. D., SD, R., Akbari, A., A, A., …investigators, T. E. (2024). Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults. Age and ageing, 53(3), Article afae057. https://doi.org/10.1093/ageing/afae057

Falls are common in older adults and can devastate personal independence through injury such as fracture and fear of future falls. Methods to identify people for falls prevention interventions are currently limited, with high risks of bias in publish... Read More about Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults..

Prognostic factors for liver, blood and kidney adverse events from glucocorticoid sparing immune-suppressing drugs in immune-mediated inflammatory diseases: a prognostic systematic review (2024)
Journal Article
Leaviss, J., Carroll, C., Essat, M., van der Windt, D., J Grainge, M., Card, T., …Abhishek, A. (2024). Prognostic factors for liver, blood and kidney adverse events from glucocorticoid sparing immune-suppressing drugs in immune-mediated inflammatory diseases: a prognostic systematic review. RMD Open, 10(1), Article e003588. https://doi.org/10.1136/rmdopen-2023-003588

Background Immune-suppressing drugs can cause liver, kidney or blood toxicity. Prognostic factors for these adverse-events are poorly understood.

Purpose To ascertain prognostic factors associated with liver, blood or kidney adverse-events in peop... Read More about Prognostic factors for liver, blood and kidney adverse events from glucocorticoid sparing immune-suppressing drugs in immune-mediated inflammatory diseases: a prognostic systematic review.

Minimal Intervention of Patient Education for Low Back Pain: A Systematic Review with Meta-Analysis. (2023)
Journal Article
Gomes, L. A., Rodrigues, A. M., Windt, D., Pires, D., Afreixo, V., Canhão, H., & Cruz, E. B. (in press). Minimal Intervention of Patient Education for Low Back Pain: A Systematic Review with Meta-Analysis. Journal of Orthopaedic & Sports Physical Therapy, 1-39. https://doi.org/10.2519/jospt.2023.11865

To explore the effects of minimal intervention of patient education (MIPE) for reducing disability and pain intensity in patients with low back pain (LBP). Intervention systematic review with meta-analysis of randomized controlled trials. We sea... Read More about Minimal Intervention of Patient Education for Low Back Pain: A Systematic Review with Meta-Analysis..

Discontinuation of anti-tumour necrosis factor alpha treatment owing to blood test abnormalities, and cost-effectiveness of alternate blood monitoring strategies (2023)
Journal Article
Abhishek, A., Stevenson, M. D., Nakafero, G., Grainge, M. J., Evans, I., Alabas, O., …Williams, H. C. (2024). Discontinuation of anti-tumour necrosis factor alpha treatment owing to blood test abnormalities, and cost-effectiveness of alternate blood monitoring strategies. British Journal of Dermatology, 190(4), 559–564. https://doi.org/10.1093/bjd/ljad430

Background
There is no evidence base to support the use of 6-monthly monitoring blood tests for the early detection of liver, blood and renal toxicity during established anti-tumour necrosis factor alpha (TNFα) treatment.

Objectives
To evaluate... Read More about Discontinuation of anti-tumour necrosis factor alpha treatment owing to blood test abnormalities, and cost-effectiveness of alternate blood monitoring strategies.

Development and External Validation of Individualized Prediction Models for Pain Intensity Outcomes in Patients With Neck Pain, Low Back Pain, or Both in Primary Care Settings (2023)
Journal Article
Archer, L., Snell, K. I. E., Stynes, S., Axén, I., Dunn, K. M., Foster, N. E., …Hill, J. C. (in press). Development and External Validation of Individualized Prediction Models for Pain Intensity Outcomes in Patients With Neck Pain, Low Back Pain, or Both in Primary Care Settings. Physical Therapy, 103(11), Article pzad128. https://doi.org/10.1093/ptj/pzad128

Objective
The purpose of this study was to develop and externally validate multivariable prediction models for future pain intensity outcomes to inform targeted interventions for patients with neck or low back pain in primary care settings.

Metho... Read More about Development and External Validation of Individualized Prediction Models for Pain Intensity Outcomes in Patients With Neck Pain, Low Back Pain, or Both in Primary Care Settings.

Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation. (2023)
Journal Article
Nakafero, G., Card, T., Grainge, M. J., Williams, H. C., Taal, M. W., Aithal, G. P., …Abhishek, A. (2023). Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation. EClinicalMedicine, 64, Article 102213. https://doi.org/10.1016/j.eclinm.2023.102213

Background
Patients established on thiopurines (e.g., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These side-effects are uncommon during long-term treatment. We deve... Read More about Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation..

Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank (2023)
Journal Article
Runhaar, J., A Holden, M., Hattle, M., Quicke, J., Healey, E. L., van der Windt, D., …Menek, M. Y. (2023). Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank. RMD Open, 9(3), Article e003220. https://doi.org/10.1136/rmdopen-2023-003220

Objectives: To evaluate mediating factors for the effect of therapeutic exercise on pain and physical function in people with knee/hip osteoarthritis (OA).

Methods: For Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (... Read More about Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank.