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Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review. (2024)
Journal Article
Wynne-Jones, G., Wainwright, E., Goodson, N., Jordan, J., Legha, A., Parchment, M., …Peat, G. (2024). Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10205-y

It is difficult to predict which employees, in particular those with musculoskeletal pain, will return to work quickly without additional vocational advice and support, which employees will require this support and what levels of support are most app... Read More about Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review..

Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study (2024)
Journal Article
Lumley, S., Yu, D., Wilkie, R., Jordan, K. P., & Peat, G. (2024). Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study. Primary Health Care Research & Development, 25, 1-8. https://doi.org/10.1017/S1463423624000070

Background: Chronic musculoskeletal pain and anxiety/depression are significant public health problems. We hypothesised that adults with both conditions constitute a group at especially high risk of future cardiovascular health outcomes. Aim: To... Read More about Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study.

Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50 (2024)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., Kingston, A., & Wilkie, R. (2024). Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50. Scientific Reports, 14(1), Article 5936. https://doi.org/10.1038/s41598-024-53095-z

Although retirement ages are rising in the United Kingdom and other countries, the average number of years people in England can expect to spend both healthy and work from age 50 (Healthy Working Life Expectancy; HWLE) is less than the number of year... Read More about Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50.

The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. (2024)
Journal Article
Parmar, S. S., Mohamed, M. O., Mamas, M. A., & Wilkie, R. (in press). The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. Expert Review of Cardiovascular Therapy, 22(1-3), 1-9. https://doi.org/10.1080/14779072.2024.2311696

The prevalence of osteoarthritis (OA) and cardiovascular disease are increasing and both conditions share similar risk factors. We investigated the association between OA and receipt of invasive managements and clinical outcomes in patients with acut... Read More about The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients..

Work Ability in the Year after Rehabilitation—Results from the RehabNytte Cohort (2023)
Journal Article
Skinnes, M. N., Moe, R. H., Johansen, T., Lyby, P. S., Eid, I., Fagertun, T. C., …Dahl, K. (in press). Work Ability in the Year after Rehabilitation—Results from the RehabNytte Cohort. Journal of Clinical Medicine, 12(23), Article 7391. https://doi.org/10.3390/jcm12237391

Background: There is limited knowledge regarding the impact of rehabilitation on work ability. The aim of this study was to explore factors associated with work ability 12 months following a multidisciplinary rehabilitation program in a cohort with d... Read More about Work Ability in the Year after Rehabilitation—Results from the RehabNytte Cohort.

Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017 (2023)
Journal Article
Yu, D., Huang, X., Mamas, M., & Wilkie, R. (2023). Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017. RMD Open, 9(3), Article e003298. https://doi.org/10.1136/rmdopen-2023-003298

Objectives: To compare the annual and period prevalence of modifiable cardiovascular risk factors (MCVRFs) between populations with and without osteoarthritis (OA) in the UK over 25 years. Methods: 215 190 patients aged 35 years and over from the... Read More about Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017.

Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain (2023)
Journal Article
Lynch, M., Peat, G., Jordan, K., Yu, D., & Wilkie, R. (2023). Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain. European Journal of Pain, https://doi.org/10.1002/ejp.2148

Background Chronic pain affects up to half of UK adults, impacting quality of life and demand on local health services. Whilst local health planning is currently based on subnational prevalence estimates, associations between pain and sociodemograph... Read More about Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain.

OP0179-HPR CHANGES IN WORK ABILITY FOLLOWING REHABILITATION (2023)
Presentation / Conference
Nilsen Skinnes, M., Moe, R. H., Johansen, T., Bruun-Hanssen, H., Dahl, K., Eid, I., …Uhlig, T. (2023, May). OP0179-HPR CHANGES IN WORK ABILITY FOLLOWING REHABILITATION. Paper presented at EULAR 2023 European Congress of Rheumatology, Milan, Italy

Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019 (2022)
Journal Article
Yu, D., Jordan, K. P., Wilkie, R., Bailey, J., Fitzpatrick, J., Ali, N., …Peat, G. (2022). Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019. Rheumatology Advances in Practice, 7(1), https://doi.org/10.1093/rap/rkac106

Objective To determine whether socioeconomic inequalities in primary care consultation rates for two major, disabling musculoskeletal conditions in England narrowed or widened between 2004-2019. Methods We analysed data from Clinical Practice Re... Read More about Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019.

2021 EULAR points to consider to support people with rheumatic and musculoskeletal diseases to participate in healthy and sustainable paid work (2022)
Journal Article
Boonen, A., Webers, C., Butink, M., Barten, B., Betteridge, N., Black, D. C., …Verstappen, S. M. M. (2023). 2021 EULAR points to consider to support people with rheumatic and musculoskeletal diseases to participate in healthy and sustainable paid work. Annals of the Rheumatic Diseases, 82(1), 57-64. https://doi.org/10.1136/ard-2022-222678

As part of its strategic objectives for 2023, EULAR aims to improve the work participation of people with rheumatic and musculoskeletal diseases (RMDs). One strategic initiative focused on the development of overarching points to consider (PtC) to s... Read More about 2021 EULAR points to consider to support people with rheumatic and musculoskeletal diseases to participate in healthy and sustainable paid work.

Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness (2022)
Journal Article
Peat, G., Jordan, K., Wilkie, R., Corp, N., Van Der Windt, D., Yu, D., …Ali, N. (2022). Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness. Journal of Public Health, 44(3), e376–e387. https://doi.org/10.1093/pubmed/fdac014

Background It is unclear whether seven interventions recommended by Public Health England for preventing and managing common musculoskeletal conditions reduce or widen health inequalities in adults with musculoskeletal conditions. Methods We used cit... Read More about Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness.

Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases (2022)
Journal Article
Yu, D., Missen, M., P Jordan, K., Edwards, J., Bailey, J., Wilkie, R., …Peat, G. (2022). Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases. Clinical Epidemiology, 14, 179-189. https://doi.org/10.2147/CLEP.S337323

Purpose: To compare estimates of annual person-consulting incidence and prevalence of low back pain (LBP) and osteoarthritis for two national English electronic health record databases (Clinical Practice Research Datalink (CPRD) Aurum and CPRD GOLD).... Read More about Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases.

Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations (2022)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., & Wilkie, R. (2022). Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations. Scientific reports, 12(1), Article 2408. https://doi.org/10.1038/s41598-022-06490-3

Retirement ages are rising in many countries to offset the challenges of population ageing, but osteoarthritis is an age-associated disease that is becoming more prevalent and may limit capacity to work until older ages. We aimed to assess the impact... Read More about Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations.

Projections of healthy working life expectancy in England to the year 2035 (2022)
Journal Article
Wilkie, Bucknall, & Lynch. (2022). Projections of healthy working life expectancy in England to the year 2035. https://doi.org/10.1038/s43587-021-00161-0

UK state pension age is rising in response to life expectancy gains but population health and job opportunities may not be sufficient to achieve extended working lives1,2,3. This study aimed to estimate future trends in healthy working life expectanc... Read More about Projections of healthy working life expectancy in England to the year 2035.

Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies. (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies. Journal of Diabetes and Clinical Research, 3(3), https://doi.org/10.33696/diabetes.3.042

Background: People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities... Read More about Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies..

338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study (2021)
Journal Article
Yu, D., Jordan, K., Bailey, J., Peat, G., & Wilkie, R. (2021). 338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study. International Journal of Epidemiology, 50(Supplement_1), https://doi.org/10.1093/ije/dyab168.739

Background Patient Reported Outcome Measures (PROM) collected in surveys allow understanding of the health at the population-level. We aimed to test the feasibility of estimating health status as measured by PROMs through ecological prediction model... Read More about 338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study.

496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis (2021)
Journal Article
Huang, M., Yu, D., Wilkie, R., & Mamas, M. (2021). 496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis. International Journal of Epidemiology, i105 - i105. https://doi.org/10.1093/ije/dyab168.295

Abstract Background Osteoarthritis (OA) has a major impact on the global burden of disease and is associated with poorer cardiovascular disease (CVD) outcomes. However it’s unclear whether people with OA have higher long-term (10-year) CVD risk comp... Read More about 496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis.

OP0259-HPR THE EFFECT OF OSTEOARTHRITIS ON HEALTHY WORKING LIFE EXPECTANCY AT AGE 50 IN ENGLAND (2021)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., & Wilkie, R. (2021). OP0259-HPR THE EFFECT OF OSTEOARTHRITIS ON HEALTHY WORKING LIFE EXPECTANCY AT AGE 50 IN ENGLAND. Annals of the Rheumatic Diseases, 80(Suppl 1), 158.2-158. https://doi.org/10.1136/annrheumdis-2021-eular.2349

Retirement ages are rising in many countries due to population ageing and increasing life expectancy. However, poor health, comorbidity and workplace factors are major reasons for work absence and it is unclear if people in later working-age life (ag... Read More about OP0259-HPR THE EFFECT OF OSTEOARTHRITIS ON HEALTHY WORKING LIFE EXPECTANCY AT AGE 50 IN ENGLAND.

Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies. MedRxiv, https://doi.org/10.1101/2021.02.14.21251130v1

Background People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities f... Read More about Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies.

Estimating the population health burden of musculoskeletal conditions using primary care electronic health records (2021)
Journal Article
Yu, D., Peat, G., Jordan, K., Bailey, J., Prieto-Alhambra, D., Robinson, D., …Wilkie, R. (2021). Estimating the population health burden of musculoskeletal conditions using primary care electronic health records. Rheumatology, 60(10), 4832-4843. https://doi.org/10.1093/rheumatology/keab109

Objectives Better indicators from affordable, sustainable data sources are needed to monitor population burden of musculoskeletal conditions. We propose five indicators of musculoskeletal health and assessed if routinely available primary care elect... Read More about Estimating the population health burden of musculoskeletal conditions using primary care electronic health records.

The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction (2020)
Journal Article
Parmar, S., Mohamed, M., Wilkie, R., & Mamas, M. (2020). The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction. European Heart Journal, 41(S2), 1660 - 1660. https://doi.org/10.1093/ehjci/ehaa946.1660

Background People with osteoarthritis (OA) have an increased risk of cardiovascular disease, including acute myocardial infarction (AMI). Despite OA being the most common joint condition and the fastest increasing major health condition, there is li... Read More about The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction.

SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018 (2020)
Presentation / Conference
Robinson, D., Craig, R., Lane, J., Andrew, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, August). SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018. Poster presented at World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020), Spain (virtual)

Objective: Recent RCTs have demonstrated little efficacy of certain shoulder surgeries. To investigate the trend in shoulder surgery incidence over time overall and by surgery type. Methods: Data were obtained from UK primary care electronic healt... Read More about SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018.

Natural History of Social Participation in the Very Old: Findings from the Newcastle 85+ Study. (2020)
Journal Article
Wilkie. (2020). Natural History of Social Participation in the Very Old: Findings from the Newcastle 85+ Study. Journal of Aging and Health, 898264320944672 - ?. https://doi.org/10.1177/0898264320944672

Objective: To describe the natural history of social participation in people aged 85 years and over. Methods: Prospective cohort study; Newcastle 85+ study. Data were collected at baseline (n = 850) and at 18-, 36- and 60-month follow-ups (n = 344).... Read More about Natural History of Social Participation in the Very Old: Findings from the Newcastle 85+ Study..

Population-based estimates of healthy working life expectancy in England at age 50 years: analysis of data from the English Longitudinal Study of Ageing. (2020)
Journal Article
Bucknall, M., & Wilkie, R. (2020). Population-based estimates of healthy working life expectancy in England at age 50 years: analysis of data from the English Longitudinal Study of Ageing. The Lancet Public Health, 5(7), e395 - e403. https://doi.org/10.1016/S2468-2667%2820%2930114-6

BACKGROUND: Retirement ages are rising in many countries to offset the challenges of population ageing, but people's capacity to work for more years in their later working life (>50 years) is unclear. We aimed to estimate healthy working life expecta... Read More about Population-based estimates of healthy working life expectancy in England at age 50 years: analysis of data from the English Longitudinal Study of Ageing..

THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016 (2020)
Presentation / Conference
Robinson, D., Lane, J., Craig, R., Judge, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, June). THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016. Poster presented at EULAR 2020

Background: The lifetime prevalence of lower back pain is between 60% and 70%, with surgical treatments spared for those not responding to other options. Objectives: To investigate the age, gender and socio-economic status differences in back pain... Read More about THE DESCRIPTIVE EPIDEMIOLOGY AND SECULAR TRENDS OF LOWER BACK PAIN PROCEDURES IN ROUTINE UK NHS CARE FROM 2000 TO 2016.

Managing work participation for people with rheumatic and musculoskeletal diseases. (2020)
Journal Article
Wilkie, R., & Lynch, M. (2020). Managing work participation for people with rheumatic and musculoskeletal diseases. https://doi.org/10.1016/j.berh.2020.101517

Improving work participation for individuals with rheumatic and musculoskeletal diseases (RMDs), has gained increasing interest over the last 10 years. New approaches are based upon increasing adoption of a biopsychosocial approach to improving work... Read More about Managing work participation for people with rheumatic and musculoskeletal diseases..

Extending Working Lives: A Systematic Review of Healthy Working Life Expectancy at Age 50 (2020)
Journal Article
Parker, M., Bucknall, M., Jagger, C., Wilkie, R., & Lynch, M. (2020). Extending Working Lives: A Systematic Review of Healthy Working Life Expectancy at Age 50. Social Indicators Research, https://doi.org/10.1007/s11205-020-02302-1

Retirement ages for receipt of state/social pensions are rising in many countries in response to population ageing and increasing life expectancy. However, sickness absence and early retirement for health reasons (especially among adults aged?=?50) p... Read More about Extending Working Lives: A Systematic Review of Healthy Working Life Expectancy at Age 50.

Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study. (2019)
Journal Article
Welsh, V., Mallen, C., Ogollah, R., Wilkie, R., & McBeth, J. (2019). Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study. PloS one, -. https://doi.org/10.1371/journal.pone.0226268

Older people are continuing to fall despite fall prevention guidelines targeting known falls' risk factors. Multisite pain is a potential novel falls' risk factor requiring further exploration. This study hypothesises that: (1) an increasing number o... Read More about Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study..

Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model (2019)
Journal Article
Wilkie, R., Singh Parmar, S., Blagojevic-Bucknall, M., Smith, D., Thomas, M. J., Seale, B. J., …Peat, G. (2019). Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model. RMD Open, 5(2), Article e001048. https://doi.org/10.1136/rmdopen-2019-001048

Objectives: To identify potentially modifiable factors that mediate the association between symptomatic osteoarthritis (OA) and premature mortality. Methods: A population-based prospective cohort study; primary care medical record data were linked to... Read More about Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model.

Why so Fast? A Focus on Reasons for an Increase in Arthritis-Attributable Activity Limitation Trends, 2002-2017 (2019)
Presentation / Conference
Theis, K., Boring, M., & Wilkie, R. (2019, November). Why so Fast? A Focus on Reasons for an Increase in Arthritis-Attributable Activity Limitation Trends, 2002-2017. Poster presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: “Arthritis-attributable activity limitation” (AAAL) is linked to many potentially modifiable characteristics (e.g., work disability, physical inactivity, obesity). By 2015, prevalence of AAAL among adults =18 with arthritis had in... Read More about Why so Fast? A Focus on Reasons for an Increase in Arthritis-Attributable Activity Limitation Trends, 2002-2017.

TARGETS FOR REDUCING PREMATURE MORTALITY IN OLDER ADULTS WITH OSTEOARTHRITIS: RESULTS FROM A NOVEL PATH ANALYSIS WITHIN A COX PROPORTIONAL HAZARDS MODEL (2019)
Journal Article
Wilkie, R., Parmar, S., & Bucknall, M. (2019). TARGETS FOR REDUCING PREMATURE MORTALITY IN OLDER ADULTS WITH OSTEOARTHRITIS: RESULTS FROM A NOVEL PATH ANALYSIS WITHIN A COX PROPORTIONAL HAZARDS MODEL. Annals of the Rheumatic Diseases, 78-S2, 152 - 153. https://doi.org/10.1136/annrheumdis-2019-eular.5862

Objectives The objectives of this study were to identify potential mechanisms of the impact of osteoarthritis on mortality and examine the role of modifiable targets (anxiety, depression, insomnia and walking frequency) for health professionals in rh... Read More about TARGETS FOR REDUCING PREMATURE MORTALITY IN OLDER ADULTS WITH OSTEOARTHRITIS: RESULTS FROM A NOVEL PATH ANALYSIS WITHIN A COX PROPORTIONAL HAZARDS MODEL.

SOCIAL HEALTH PROFILES IN PRIMARY CARE CONSULTERS FOR COMMON MUSCULOSKELETAL CONDITIONS: OPERATIONALISATION OF THE PROMIS SHORT FORM TOOL IN PATIENTS WITH MUSCULOSKELETAL CONDITIONS (2019)
Journal Article
Uraiby, Y., & Wilkie, R. (2019). SOCIAL HEALTH PROFILES IN PRIMARY CARE CONSULTERS FOR COMMON MUSCULOSKELETAL CONDITIONS: OPERATIONALISATION OF THE PROMIS SHORT FORM TOOL IN PATIENTS WITH MUSCULOSKELETAL CONDITIONS. Rheumatology, 58(S3), Article kez107.023. https://doi.org/10.1093/rheumatology/kez107.023

Reasons for retirement in older adults with osteoarthritis (2019)
Journal Article
Walters, B., & Wilkie, R. (2019). Reasons for retirement in older adults with osteoarthritis. Rheumatology, 58(S3), 107 - 107. https://doi.org/10.1093/rheumatology/kez108.068

Background: Osteoarthritis begins to emerge as a major cause of functional limitation, work disability and retirement from age 50 years onwards. With policies encouraging extensions to working life, older workers with osteoarthritis will be expected... Read More about Reasons for retirement in older adults with osteoarthritis.

The impact of socioeconomic status on the link between osteoarthritis and the onset of common comorbidities (2019)
Journal Article
Wilkie, R., Kaur, K., & Hayward, R. A. (2019). The impact of socioeconomic status on the link between osteoarthritis and the onset of common comorbidities. Clinical and Experimental Rheumatology, 37(1), 44-48

Objectives The temporal relationship between osteoarthritis and comorbidity is unclear and may vary with socioeconomic status. The aims of this study were to identify if osteoarthritis was associated with onset of common comorbidities, and if the ass... Read More about The impact of socioeconomic status on the link between osteoarthritis and the onset of common comorbidities.

Secular trends in work disability and its relationship to musculoskeletal pain and mental health: a time-trend analysis using five cross-sectional surveys (2002-2010) in the general population. (2018)
Journal Article
Wynne-Jones, G., Chen, Y., Croft, P., Peat, G., Wilkie, R., Jordan, K., & Petersson, I. F. (2018). Secular trends in work disability and its relationship to musculoskeletal pain and mental health: a time-trend analysis using five cross-sectional surveys (2002-2010) in the general population. Occupational and Environmental Medicine, 877-883. https://doi.org/10.1136/oemed-2018-105171

OBJECTIVES: International evidence suggests that rates of inability to work because of illness can change over time. We hypothesised that one reason for this is that the link between inability to work and common illnesses, such as musculoskeletal pai... Read More about Secular trends in work disability and its relationship to musculoskeletal pain and mental health: a time-trend analysis using five cross-sectional surveys (2002-2010) in the general population..

Pain and mortality: mechanisms for a relationship (2018)
Journal Article
Smith, D., Wilkie, R., Croft, P., Parmar, S., & McBeth, J. (2018). Pain and mortality: mechanisms for a relationship. PAIN, 1112 -1118. https://doi.org/10.1097/j.pain.0000000000001193

Moderate to severe chronic pain affects 1 in 5 adults and its impact increases with age. People with chronic pain that interferes with their lives have an increased risk of mortality. Identifying how interfering chronic pain can lead to mortality may... Read More about Pain and mortality: mechanisms for a relationship.

Pain and Mortality in Older Adults: The Influence of Pain Phenotype. (2018)
Journal Article
Smith, D., Wilkie, R., Croft, P., & McBeth, J. (2018). Pain and Mortality in Older Adults: The Influence of Pain Phenotype. Arthritis Care and Research, 70(2), 236 - 243. https://doi.org/10.1002/acr.23268

OBJECTIVE: Moderate to severe chronic pain affects 1 in 5 adults. Pain may increase the risk of mortality, but the relationship is unclear. This study investigated whether mortality risk was influenced by pain phenotype, characterized by pain extent... Read More about Pain and Mortality in Older Adults: The Influence of Pain Phenotype..

The role of environmental factors for the onset of restricted mobility outside the home among older adults with osteoarthritis: a prospective cohort study (2017)
Journal Article
Rantakokko, M., & Wilkie, R. (2017). The role of environmental factors for the onset of restricted mobility outside the home among older adults with osteoarthritis: a prospective cohort study. BMJ Open, 7(6), e012826 -?. https://doi.org/10.1136/bmjopen-2016-012826

OBJECTIVES: The study examines how environmental factors contribute to the onset of restricted mobility outside the home among older adults with osteoarthritis. METHODS: This is a prospective cohort study of adults aged 50 years and older with osteoa... Read More about The role of environmental factors for the onset of restricted mobility outside the home among older adults with osteoarthritis: a prospective cohort study.

Evidence for strategies that improve recruitment and retention of adults aged 65 years and over in randomised trials and observational studies: a systematic review (2017)
Journal Article
Lacey, R., Wilkie, R., Wynne-Jones, G., Jordan, J., Wersocki, E., & McBeth, J. (2017). Evidence for strategies that improve recruitment and retention of adults aged 65 years and over in randomised trials and observational studies: a systematic review. Age and ageing, 46(6), 895- 903. https://doi.org/10.1093/ageing/afx057

Background: adults aged =65 years are often excluded from health research studies. Lack of representation reduces generalisability of treatments for this age group. Objective: to evaluate the effectiveness of strategies that improve recruitment and r... Read More about Evidence for strategies that improve recruitment and retention of adults aged 65 years and over in randomised trials and observational studies: a systematic review.

Clinical and cost-effectiveness oral abstractsO07. The role of socio-economic factors on the onset of comorbidity in primary care consulters with osteoarthritis: a prospective cohort study (2017)
Presentation / Conference
Kaur, K. A., Hayward, R. A., & Wilkie, R. (2017, April). Clinical and cost-effectiveness oral abstractsO07. The role of socio-economic factors on the onset of comorbidity in primary care consulters with osteoarthritis: a prospective cohort study. Presented at Rheumatology 2017, Birmingham ICC, England, UK

Musculoskeletal pain and co-morbid insomnia in adults; a population study of the prevalence and impact on restricted social participation. (2017)
Journal Article
Baker, S., McBeth, J., Chew-Graham, C. A., & Wilkie, R. (2017). Musculoskeletal pain and co-morbid insomnia in adults; a population study of the prevalence and impact on restricted social participation. BMC Family Practice, 17 - ?. https://doi.org/10.1186/s12875-017-0593-5

BACKGROUND: Comorbidity is common in patients consulting in primary care. Musculoskeletal pain and insomnia each increase the risk of the other. Co-occurrence may pose an increased burden on well-being. However, the prevalence and impact of co-existi... Read More about Musculoskeletal pain and co-morbid insomnia in adults; a population study of the prevalence and impact on restricted social participation..

Allostatic load and pain severity in older adults: results from the English Longitudinal Study of Ageing (2017)
Journal Article
Sibille, K. T., McBeth, J., Smith, D., & Wilkie, R. (2017). Allostatic load and pain severity in older adults: results from the English Longitudinal Study of Ageing. Experimental Gerontology, 51 - 58. https://doi.org/10.1016/j.exger.2016.12.013

Pain is common in older adults, is frequently experienced as stressful, and is associated with increased morbidity and mortality. Stress regulatory systems are adaptive to challenge and change, allostasis, until demands exceed the adaptive capacity c... Read More about Allostatic load and pain severity in older adults: results from the English Longitudinal Study of Ageing.

Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care. (2016)
Journal Article
Wilkie, R., Blagojevic-Bucknall, M., Belcher, J., Chew-Graham, C., Lacey, R. J., & McBeth, J. (2016). Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care. Medicine, 95(31), Article e4111. https://doi.org/10.1097/MD.0000000000004111

In older adults, reduced social participation increases the risk of poor health-related quality of life, increased levels of inflammatory markers and cardiovascular disease, and increased mortality. Older adults frequently present to primary care, wh... Read More about Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care..

MAINTAINING MENTAL HEALTH IN OLDER PEOPLE WITH MUSCULOSKELETAL PAIN: A LONGITUDINAL COHORT STUDY (2016)
Journal Article
Baker, S., Chew-Graham, C. A., Wilkie, R., & McBeth, J. (2016). MAINTAINING MENTAL HEALTH IN OLDER PEOPLE WITH MUSCULOSKELETAL PAIN: A LONGITUDINAL COHORT STUDY. Annals of the Rheumatic Diseases, 75(S2), 656-657. https://doi.org/10.1136/annrheumdis-2016-eular.4037

Background Reporting troublesome pain doubled the risk of the onset of depression in older people1. However the majority (84%) of those with troublesome pain remained free of depression. Social participation (SP) (i.e. recreational and functional act... Read More about MAINTAINING MENTAL HEALTH IN OLDER PEOPLE WITH MUSCULOSKELETAL PAIN: A LONGITUDINAL COHORT STUDY.

Social Participation, Loneliness and Depression (2016)
Book Chapter
Burroughs, H., & Wilkie, R. (2016). Social Participation, Loneliness and Depression. In Mental Health and Older People (57-65). Springer. https://doi.org/10.1007/978-3-319-29492-6_6

Retirement from paid employment and other changes in role can, for some older people, lead to a decline in social participation. A lack of social participation can cause loneliness, but the two states are not synonymous. Loneliness is emotional distr... Read More about Social Participation, Loneliness and Depression.

Social gradient and regional variation and in general practice consultation prevalence for osteoarthritis in England 1998–2013: Descriptive epidemiological study using data from the Clinical Practice Research Datalink (2016)
Journal Article
Dutta, A., Wilkie, R., Yu, D., & Peat, G. (2016). Social gradient and regional variation and in general practice consultation prevalence for osteoarthritis in England 1998–2013: Descriptive epidemiological study using data from the Clinical Practice Research Datalink. Osteoarthritis and Cartilage, 24, S197-S198. https://doi.org/10.1016/j.joca.2016.01.389

Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project (2015)
Journal Article
Lacey, R. J., Strauss, V. Y., Rathod, T., Belcher, J., Croft, P. R., Natvig, B., …McBeth, J. (2015). Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project. BMJ Open, 5(11), https://doi.org/10.1136/bmjopen-2015-008389

Objective Most pain in patients aged =50 years affects multiple sites and yet the predominant mode of presentation is single-site syndromes. The aim of this study was to investigate if pain sites form clusters in this population and if any such clust... Read More about Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project.

Exploring how pain leads to productivity loss in primary care consulters for osteoarthritis: a prospective cohort study (2015)
Journal Article
Wilkie, R., Hay, E. M., Croft, P., & Pransky, G. (2015). Exploring how pain leads to productivity loss in primary care consulters for osteoarthritis: a prospective cohort study. PloS one, 10(4), Article e0120042. https://doi.org/10.1371/journal.pone.0120042

OBJECTIVE: Osteoarthritis pain has become a leading cause of decreased productivity and work disability in older workers, a major concern in primary care. How osteoarthritis pain leads to decreased productivity at work is unclear; the aim of this stu... Read More about Exploring how pain leads to productivity loss in primary care consulters for osteoarthritis: a prospective cohort study.

Anticipated significant work limitation in primary care consulters with osteoarthritis: a prospective cohort study (2014)
Journal Article
Wilkie, R., Phillipson, C., Hay, E. M., & Pransky, G. (2014). Anticipated significant work limitation in primary care consulters with osteoarthritis: a prospective cohort study. BMJ Open, 4(9), Article e005221. https://doi.org/10.1136/bmjopen-2014-005221

OBJECTIVE: To describe the prevalence of expected work limitations (EWL) prior to future retirement age in osteoarthritis consulters, and the associated health, sociodemographic and workplace factors. DESIGN: Population-based prospective cohort study... Read More about Anticipated significant work limitation in primary care consulters with osteoarthritis: a prospective cohort study.

Pain at multiple body sites and health-related quality of life in older adults: results from the North Staffordshire Osteoarthritis Project. (2014)
Journal Article
Lacey, R. J., Belcher, J., Rathod, T., Wilkie, R., Thomas, E., & McBeth, J. (2014). Pain at multiple body sites and health-related quality of life in older adults: results from the North Staffordshire Osteoarthritis Project. Rheumatology, 53(11), 2071 - 2079. https://doi.org/10.1093/rheumatology/keu240

OBJECTIVES: Number of pain sites (NPS) is a potentially important marker of health-related quality of life (HRQoL) but remains unexplored in older people. This cross-sectional study investigated whether, in older people including the oldest old, NPS... Read More about Pain at multiple body sites and health-related quality of life in older adults: results from the North Staffordshire Osteoarthritis Project..

Chronic pain and mortality: a systematic review (2014)
Journal Article
Smith, D., Wilkie, R., Uthman, O., Jordan, J. L., & McBeth, J. (2014). Chronic pain and mortality: a systematic review. PloS one, 9(6), Article e99048. https://doi.org/10.1371/journal.pone.0099048

Chronic pain is common, often widespread and has a substantial impact on health and quality of life. The relationship between chronic pain and mortality is unclear. This systematic review aimed to identify and evaluate evidence for a relationship bet... Read More about Chronic pain and mortality: a systematic review.

The role of pain, physical disability, and reduced social participation in insomnia onset in community dwelling older adults: a prospective cohort study (2013)
Journal Article
Tang, N. K. Y., McBeth, J., Jordan, K. P., Blagojevic-Bucknall, M., Croft, P., & Wilkie, R. (2013). The role of pain, physical disability, and reduced social participation in insomnia onset in community dwelling older adults: a prospective cohort study. The Lancet, 382(S3), S95. https://doi.org/10.1016/s0140-6736%2813%2962520-9

Frequency and predictors of premature work loss in primary care consulters for osteoarthritis: prospective cohort study (2013)
Journal Article
Wilkie, R., Phillipson, C., Hay, E., & Pransky, G. (2014). Frequency and predictors of premature work loss in primary care consulters for osteoarthritis: prospective cohort study. Rheumatology, 53(3), 459-464. https://doi.org/10.1093/rheumatology/ket336

Objective. The objective of this study was to describe the extent of premature work loss (PWL) in OA consulters across a 6-year observation period, and associated factors. Methods. We conducted a population-based prospective cohort study set in pr... Read More about Frequency and predictors of premature work loss in primary care consulters for osteoarthritis: prospective cohort study.

Social participation in older adults with joint pain and comorbidity; testing the measurement properties of the Dutch Keele Assessment of Participation (2013)
Journal Article
Hermsen, L. A. H., Terwee, C. B., Leone, S. S., van der Zwaard, B., Smalbrugge, M., Dekker, J., …Wilkie, R. (2013). Social participation in older adults with joint pain and comorbidity; testing the measurement properties of the Dutch Keele Assessment of Participation. BMJ Open, 3(8), Article ARTN e003181. https://doi.org/10.1136/bmjopen-2013-003181

Objective The Keele Assessment of Participation (KAP) questionnaire measures person-perceived participation in 11 aspects of life. Participation allows fulfilment of valued life activities and social roles, which are important to older adults. Since... Read More about Social participation in older adults with joint pain and comorbidity; testing the measurement properties of the Dutch Keele Assessment of Participation.

Reasons Why Multimorbidity Increases the Risk of Participation Restriction in Older Adults With Lower Extremity Osteoarthritis: A Prospective Cohort Study in Primary Care (2013)
Journal Article
Wilkie, R., Blagojevic‐Bucknall, M., Jordan, K. P., Lacey, R., & McBeth, J. (2013). Reasons Why Multimorbidity Increases the Risk of Participation Restriction in Older Adults With Lower Extremity Osteoarthritis: A Prospective Cohort Study in Primary Care. Arthritis Care and Research, 65(6), 910-919. https://doi.org/10.1002/acr.21918

The Measurement Properties of the Dutch Keele Assessment of Participation Questionnaire in Older Adults with Joint Pain and Comorbidity (2013)
Presentation / Conference
Hermsen, L., Terwee, C. B., Leone, S. S., vd Zwaard, B., Smalbrugge, M., Dekker, J., …Wilkie, R. (2013, April). The Measurement Properties of the Dutch Keele Assessment of Participation Questionnaire in Older Adults with Joint Pain and Comorbidity. Poster presented at Rheumatology 2013

Background: Social participation provides an account of the wider influence of musculoskeletal conditions on functioning and captures the personal and social impact. Maintaining social participation is important to individuals with musculoskeletal co... Read More about The Measurement Properties of the Dutch Keele Assessment of Participation Questionnaire in Older Adults with Joint Pain and Comorbidity.

O22. Widespread and Regional Pain Predict Social Participation Restriction in Older Adults: A Prospective Cohort Study (2013)
Presentation / Conference
Wilkie, R., Bucknall, M., Jordan, K., & McBeth, J. (2013, April). O22. Widespread and Regional Pain Predict Social Participation Restriction in Older Adults: A Prospective Cohort Study. Paper presented at Rheumatology 2013, Birmingham, UK

Background: In older people maintaining social participation (a measure of social function and social roles, such as being a worker, carer or community member), is associated with reduced morbidity and mortality. Social participation restriction resu... Read More about O22. Widespread and Regional Pain Predict Social Participation Restriction in Older Adults: A Prospective Cohort Study.

The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study (2013)
Journal Article
Wilkie, R., Tajar, A., & McBeth, J. (2013). The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study. PloS one, 8(3), e59858 - ?. https://doi.org/10.1371/journal.pone.0059858

OBJECTIVE: Chronic musculoskeletal pain is common in older adults but the nature of its relationship with ageing is unclear. The objective for this study was to test the hypothesis that the onset of widespread pain would be associated with a decrease... Read More about The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study.

Social Participation Restriction Among US Adults With Arthritis: A Population-Based Study Using the International Classification of Functioning, Disability and Health (2013)
Journal Article
Theis, K. A., Murphy, L., Hootman, J. M., & Wilkie, R. (2013). Social Participation Restriction Among US Adults With Arthritis: A Population-Based Study Using the International Classification of Functioning, Disability and Health. Arthritis Care and Research, 65(7), 1059-1069. https://doi.org/10.1002/acr.21977

International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden (2013)
Journal Article
Jordan, K. P., Jöud, A., Bergknut, C., Croft, P., Edwards, J. J., Peat, G., …Englund, M. (2014). International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden. Annals of the Rheumatic Diseases, 73(1), 212-218. https://doi.org/10.1136/annrheumdis-2012-202634

Measures of Social Function and Participation in Musculoskeletal Populations Impact on Participation and Autonomy ( IPA), Keele Assessment of Participation (KAP), Participation Measure for Post-Acute Care (PM-PAC), Participation Objective, Participation Subjective (POPS), Rating of Perceived Participation (ROPP), and The Participation Scale (2011)
Journal Article
Wilkie, R., Jordan, J. L., Muller, S., Nicholls, E., Healey, E. L., & Van der Windt, D. A. (2011). Measures of Social Function and Participation in Musculoskeletal Populations Impact on Participation and Autonomy ( IPA), Keele Assessment of Participation (KAP), Participation Measure for Post-Acute Care (PM-PAC), Participation Objective, Participation Subjective (POPS), Rating of Perceived Participation (ROPP), and The Participation Scale. Arthritis Care and Research, 63(S11), S325-S336. https://doi.org/10.1002/acr.20641

Measurement of change in function and disability in osteoarthritis: current approaches and future challenges (2009)
Journal Article
Jordan, K. P., Wilkie, R., Muller, S., Myers, H., & Nicholls, E. (2009). Measurement of change in function and disability in osteoarthritis: current approaches and future challenges. Current Opinion in Rheumatology, 21(5), 525-530. https://doi.org/10.1097/BOR.0b013e32832e45fc

Purpose of review This review assessed current approaches to using objective and self-report measures to determine change in function and disability in osteoarthritis and identified key future challenges. Recent findings New approaches to meas... Read More about Measurement of change in function and disability in osteoarthritis: current approaches and future challenges.

Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies
Journal Article
Huang, X., Wilkie, R., Mamas, M. A., & Yu, D. Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies. arXiv, https://doi.org/10.1101/2021.02.14.21251130

Background People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities f... Read More about Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies.

Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study
Presentation / Conference
Wilkie, Yu, & Jordan. Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study. Presented at IEA WORLD CONGRESS OF EPIDEMIOLOGY 2021

Background Patient Reported Outcome Measures (PROM) collected in surveys allow understanding of the health at the population-level. We aimed to test the feasibility of estimating health status as measured by PROMs through ecological prediction models... Read More about Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study.