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Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Murugan, S., Ramasubramanian, S., Balaji, S., Maffulli, N., & Jeyaraman, M. (in press). Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review. Journal of Clinical Medicine, 13(16), Article 4794. https://doi.org/10.3390/jcm13164794

Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still n... Read More about Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review.

The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. (2024)
Journal Article
Galimzhanov, A., Tun, H. N., Sabitov, Y., Perone, F., Kursat, T. M., Tenekecioglu, E., & Mamas, M. A. (in press). The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. European Journal of Clinical Investigation, Article e14295. https://doi.org/10.1111/eci.14295

Mean platelet volume (MPV) is a widely available laboratory index, however its prognostic significance in patients with coronary artery disease (CAD) is still unclear. We intended to investigate and pool the evidence on the prognostic utility of admi... Read More about The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses..

Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk (2024)
Journal Article
Farooq, S., Xu, L., Ullah, S., Li, J., Nie, J., Ping, J., & Ying, Y. (2024). Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk. Comprehensive Reviews in Food Science and Food Safety, 23(4), Article e13399. https://doi.org/10.1111/1541-4337.13399

AbstractMilk, as a widely consumed nutrient‐rich food, is crucial for bone health, growth, and overall nutrition. The persistent application of veterinary drugs for controlling diseases and heightening milk yield has imparted substantial repercussion... Read More about Advancements and greenification potential of magnetic molecularly imprinted polymers for chromatographic analysis of veterinary drug residues in milk.

Angioembolization in the management of joint pain: current concepts. (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Ramkumar, V., Ramasubramanian, S., Patro, B. P., Maffulli, N., & Jeyaraman, M. (in press). Angioembolization in the management of joint pain: current concepts. Die Orthopädie, https://doi.org/10.1007/s00132-024-04531-5

Joint pain is a common complaint owing to its origin in inflammatory and degenerative joint diseases. Recent research has helped narrow down inadequate angiogenesis as one of the causes. Angioembolization has emerged as a treatment option for this co... Read More about Angioembolization in the management of joint pain: current concepts..

Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis (2024)
Journal Article
Bahar, J., Rahman, A., Wong, G. W., Sankaranarayanan, R., Ahmed, F. Z., Taylor, R., Fuat, A., Squire, I., Cleland, J. G., Lip, G. Y., Gamble, J. H., Masudi, S., Joseph, P. J. S., & Wong, K. Y. (2024). Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis. ESC Heart Failure, 1-9. https://doi.org/10.1002/ehf2.14841

Patients with acutely decompensated heart failure (ADHF) are usually admitted to hospital for management. There is growing interest in delivering intravenous (IV) diuretic therapy at home, in the community or at hospital day‐care units; the safety an... Read More about Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis.

The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope (2024)
Journal Article
Mercer, L., Abhishek, A., Kavirayani, A., Ahmed, A., Davidson, A., Foulkes, A., Jones, C., Nash, C., Rose-Parfitt, E., Dhillon, E., Zabate, G., Twohig, H., De Vere, H., Scott, J., Reynolds, J., Holmes, J., Hartley, K., Warrier, K., Nowak, K., Parsons, K., …Galloway, J. (in press). The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(3), Article rkae077. https://doi.org/10.1093/rap/rkae077

Lay Summary: What does this mean for patients? A revised guideline, produced by the British Society for Rheumatology (BSR), will provide up-to-date information about the safe prescribing and monitoring of the effects of non-biologic (or conventional... Read More about The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope.

Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. (2024)
Journal Article
Lawford, B. J., Allison, K., Nelligan, R., Campbell, P., Hinman, R. S., Jones, S. E., Pardo, J., Quicke, J. G., Sumithran, P., Prendergast, J., George, E. S., Holden, M. A., Foster, N. E., & Bennell, K. L. (2024). Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. Arthritis Care & Research, https://doi.org/10.1002/acr.25401

Explore the experiences of people with knee osteoarthritis who received a very low energy diet (VLED) and exercise program from a physiotherapist. Mixed methods study involving questionnaires (n=42) and semi-structured interviews (n=22) with randomiz... Read More about Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study..

Workplace factors impacting the wellbeing of diagnostic radiographers in clinical practice: A literature review (2024)
Journal Article
Ismail, Y., Shiner, N., & Tucker, R. (2024). Workplace factors impacting the wellbeing of diagnostic radiographers in clinical practice: A literature review. Journal of Medical Imaging and Radiation Sciences, 55(4), Article 101439. https://doi.org/10.1016/j.jmir.2024.101439

Introduction
The Coronavirus (COVID-19) pandemic resulted in an emphasis on external factors affecting the wellbeing of staff within the National Health Service. There is a national shortage of diagnostic radiogra... Read More about Workplace factors impacting the wellbeing of diagnostic radiographers in clinical practice: A literature review.

Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study (2024)
Journal Article
Sim, R. R. J., Soon, W., Smith, H. E., Griva, K., & Wong, S. K. W. (2024). Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study. BMJ Open, 14(7), Article e086133. https://doi.org/10.1136/bmjopen-2024-086133

Aim: Young-onset type 2 diabetes (YOD) is associated with poorer clinical outcomes. To support the development of more effective diabetes self-management education (DSME) programmes, this study aimed to understand the preferences of young adults with... Read More about Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study.

Machine-learning clustering analysis identifies novel phenogroups in patients with ST-elevation acute myocardial infarction. (2024)
Journal Article
Matetic, A., Kyriacou, T., & Mamas, M. A. (2024). Machine-learning clustering analysis identifies novel phenogroups in patients with ST-elevation acute myocardial infarction. International Journal of Cardiology, 411, 1-9. https://doi.org/10.1016/j.ijcard.2024.132272

Machine learning clustering of patients with ST-elevation acute myocardial infarction (STEMI) may provide important insights into their risk profile, management and prognosis. All adult discharges for STEMI in the National Inpatient Sample (October 2... Read More about Machine-learning clustering analysis identifies novel phenogroups in patients with ST-elevation acute myocardial infarction..

Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy. (2024)
Journal Article
Yang, M.-L., Hu, C.-Y., Lee, Y.-C., Chang, C.-C., Chen, Y.-C., Lee, P.-R., Su, B.-H., Chen, P.-C., Shiau, A.-L., Shieh, G.-S., Wu, C.-L., & Wu, P. (in press). Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy. Stem Cells Translational Medicine, Article szae039. https://doi.org/10.1093/stcltm/szae039

Oncolytic adenoviruses have emerged as a promising therapeutic approach for cancer therapy. However, systemic delivery of the viruses to metastatic tumors remains a major challenge. Mesenchymal stem cells (MSCs) possess tumor tropism property and can... Read More about Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy..

GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study (2024)
Journal Article
Archer, C., Kessler, D., Wiles, N., Chew-Graham, C. A., & Turner, K. (2024). GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study. British Journal of General Practice (BJGP), Article BJGP.2024.0091. https://doi.org/10.3399/BJGP.2024.0091

Between 2003-2018, incident prescriptions of beta-blockers for anxiety increased substantially, particularly in young adults. NICE guidance for anxiety does not recommend beta-blockers, probably due to a lack of evidence to support such use. Recent r... Read More about GPs’ views of prescribing beta- blockers for people with anxiety disorders: a qualitative study.

Exploring the molecular mechanisms of MSC-derived exosomes in Alzheimer's disease: Autophagy, insulin and the PI3K/Akt/mTOR signaling pathway. (2024)
Journal Article
Ebrahim, N., Al Saihati, H. A., Alali, Z., Aleniz, F. Q., Mahmoud, S. Y. M., Badr, O. A., Dessouky, A. A., Mostafa, O., Hussien, N. I., Farid, A. S., El-Sherbiny, M., Salim, R. F., Forsyth, N. R., Ali, F. E. M., & Alsabeelah, N. F. (2024). Exploring the molecular mechanisms of MSC-derived exosomes in Alzheimer's disease: Autophagy, insulin and the PI3K/Akt/mTOR signaling pathway. Biomedicine and Pharmacotherapy, 176, Article 116836. https://doi.org/10.1016/j.biopha.2024.116836

Alzheimer's disease (AD) is a devastating neurological condition characterized by cognitive decline, motor coordination impairment, and amyloid plaque accumulation. The underlying molecular mechanisms involve oxidative stress, inflammation, and neuro... Read More about Exploring the molecular mechanisms of MSC-derived exosomes in Alzheimer's disease: Autophagy, insulin and the PI3K/Akt/mTOR signaling pathway..

Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review. (2024)
Journal Article
Amini-Salehi, E., Mahapatro, A., Korsapati, R. R., Korsapati, A. R., Jain, S. M., Babaeizad, A., Mohammadi, S., Rashidian, P., Hashemi, M., Dave, T., Jamilian, P., Hassanipour, S., Keivanlou, M.-H., & Patel, D. (in press). Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review. Nutrition, Metabolism and Cardiovascular Diseases, https://doi.org/10.1016/j.numecd.2024.05.017

Given the epidemic proportions of type 2 diabetes mellitus (T2DM) globally, it's crucial to comprehensively understand the factors influencing its management. The gut microbiome, known for its influence on various aspects of health, has emerged as a... Read More about Exploring the relationship between gut microbiome modulation and blood pressure in type 2 diabetes: An umbrella review..

Radiation Exposure, Training, and Safety in Cardiology. (2024)
Journal Article
Tamirisa, K. P., Alasnag, M., Calvert, P., Islam, S., Bhardwaj, A., Pakanati, K., Zieroth, S., Razminia, M., Dalal, A. S., Mamas, M., Russo, A. M., & Kort, S. (2024). Radiation Exposure, Training, and Safety in Cardiology. JACC: Advances, 3(4), Article 100863. https://doi.org/10.1016/j.jacadv.2024.100863

Exposure to ionizing radiation is an inherent occupational health hazard in clinical cardiology. Health risks have been reported previously, including predilection to cancer. In addition, orthopedic injury due to prolonged wearing of heavy protective... Read More about Radiation Exposure, Training, and Safety in Cardiology..

Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T). (2024)
Journal Article
Miranda, R. N., Qiu, F., Manoragavan, R., Austin, P. C., Naimark, D. M. J., Fremes, S. E., Ko, D. T., Madan, M., Mamas, M. A., Sud, M. K., Tam, D., & Wijeysundera, H. C. (2024). Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T). Journal of the American Heart Association, 13(5), Article e033768. https://doi.org/10.1161/JAHA.123.033768

Transcatheter aortic valve implantation (TAVI) has seen indication expansion and thus exponential growth in demand over the past decade. In many jurisdictions, the growing demand has outpaced capacity, increasing wait times and preprocedural adverse... Read More about Transcatheter Aortic Valve Implantation Wait-Time Management: Derivation and Validation of the Canadian TAVI Triage Tool (CAN3T)..

Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues. (2023)
Journal Article
Fezza, E., Roberts, J. M., Bruce, T. J. A., Walsh, L. E., Gaffney, M. T., Pope, T. W., Bruce, T. J. A., & Gaffney, M. T. (in press). Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues. Pest Management Science, 10.1002/ps.7665. https://doi.org/10.1002/ps.7665

Monitoring is an integral component of integrated pest management (IPM) programmes used to inform crop management decisions. Vine weevil, Otiorhynchus sulcatus F. (Coleoptera: Curculionidae), continues to cause economically significant losses in hort... Read More about Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues..

Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population (2023)
Journal Article
Price, A., Smith, J. R., Mughal, F., Salimi, A., Melendez-Torres, G. J., & Newlove-Delgado, T. (2023). Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population. BMJ Open, 13(7), Article e068184. https://doi.org/10.1136/bmjopen-2022-068184

Introduction: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and adolescents, with an average worldwide prevalence of 5%. Up to 40% of young people continue to experience symptoms into adult... Read More about Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population.