Outputs (79)

Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project (2015)
Journal Article
Lacey, R. J., Strauss, V. Y., Rathod, T., Belcher, J., Croft, P. R., Natvig, B., …McBeth, J. (2015). Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project. BMJ Open, 5(11), https://doi.org/10.1136/bmjopen-2015-008389

Objective Most pain in patients aged =50 years affects multiple sites and yet the predominant mode of presentation is single-site syndromes. The aim of this study was to investigate if pain sites form clusters in this population and if any such clust... Read More about Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project.

One-year trajectories of depression and anxiety symptoms in older patients presenting in general practice with musculoskeletal pain: A latent class growth analysis. (2015)
Journal Article
Rzewuska, M., Mallen, C. D., Strauss, V. Y., Belcher, J., & Peat, G. (2015). One-year trajectories of depression and anxiety symptoms in older patients presenting in general practice with musculoskeletal pain: A latent class growth analysis. Journal of Psychosomatic Research, 79(3), 195 - 201. https://doi.org/10.1016/j.jpsychores.2015.05.016

OBJECTIVE: Distinguishing transient from persistent anxiety and depression symptoms in older people presenting to general practice with musculoskeletal pain is potentially important for effective management. This study sought to identify distinct pos... Read More about One-year trajectories of depression and anxiety symptoms in older patients presenting in general practice with musculoskeletal pain: A latent class growth analysis..

O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink (2015)
Journal Article
Clarson, L. E., Hider, S. L., Belcher, J., Roddy, E., Heneghan, C., & Mallen, C. D. (2015). O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink. Rheumatology, 54(S1), https://doi.org/10.1093/rheumatology/kev084.001

Background: Current evidence suggests that gout is an independent risk factor for excess cardiovascular morbidity and mortality; yet, suboptimal care for patients with gout in primary care persists. We aimed to identify risk factors specific to these... Read More about O31. Gout and Risk of Subsequent Vascular Event: A Discrete-Time Event History Analysis in the Clinical Practice Research Datalink.

Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies (2015)
Journal Article
Mallen, Roddy, & Belcher. (2015). Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies. Arthritis Research and Therapy, 17, Article 90. https://doi.org/10.1186/s13075-015-0610-9

ntroduction
To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis.

Methods
Systematic review and meta-... Read More about Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies.

Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis (2015)
Journal Article
Roddy, Mallen, Belcher, Clarson, & Hider. (2015). Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. European Journal of Preventive Cardiology, 22(3), 335 -343. https://doi.org/10.1177/2047487313514895

BACKGROUND: Hyperuricaemia, the biochemical precursor to gout, has been shown to be an independent risk factor for mortality from cardiovascular disease (CVD), although studies examining the clinical phenomenon of gout and risk of CVD mortality repor... Read More about Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis.

Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink (2015)
Journal Article
Roddy, Mallen, Belcher, & Hider. (2015). Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Annals of the Rheumatic Diseases, 642 - 647. https://doi.org/10.1136/annrheumdis-2014-206432

OBJECTIVES: To determine whether gout increases risk of incident coronary heart disease (CHD), cerebrovascular (CVD) and peripheral vascular disease (PVD) in a large cohort of primary care patients with gout, since there have been no such large studi... Read More about Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink.

Response to: 'Risk of vascular disease with gout: overadjustment of the statistical analyses?' by van Durme et al. (2015)
Journal Article
Roddy, Mallen, Belcher, Clarson, & Hider. (2015). Response to: 'Risk of vascular disease with gout: overadjustment of the statistical analyses?' by van Durme et al. Annals of the Rheumatic Diseases, 74(1), e10 - ?. https://doi.org/10.1136/annrheumdis-2014-206723

THE INCIDENCE OF NEW PSEUDOMONAS AERUGINOSA INFECTION IN CHILDREN WITH CYSTIC FIBROSIS (2014)
Presentation / Conference
Gilchrist, F. J., Belcher, J., Jones, A. M., Smith, D., Smyth, A., Southern, K. W., …Lenney, W. (2014, December). THE INCIDENCE OF NEW PSEUDOMONAS AERUGINOSA INFECTION IN CHILDREN WITH CYSTIC FIBROSIS. Poster presented at British Thoracic Society Winter Meeting 2014, The Queen Elizabeth II Conference Centre, Broad Sanctuary, Westminster, London

Introduction Pseudomonas aeruginosa (PA) is one of the most important pathogens in cystic fibrosis (CF). Although there is a wealth of data about the prevalence of chronic PA infection, there is a paucity of evidence about the incidence of new PA inf... Read More about THE INCIDENCE OF NEW PSEUDOMONAS AERUGINOSA INFECTION IN CHILDREN WITH CYSTIC FIBROSIS.

EVALUATION OF SALIVA BIOMARKERS AS INDICATORS OF HEALTH STATUS AND EXACERBATIONS IN COPD (2014)
Journal Article
Patel, N., Jones, P., Adamson, V., Thorpe, G., Belcher, J., & Spiteri, M. (2014). EVALUATION OF SALIVA BIOMARKERS AS INDICATORS OF HEALTH STATUS AND EXACERBATIONS IN COPD. Thorax, 69(S2), A102-A103. https://doi.org/10.1136/thoraxjnl-2014-206260.205

Saliva is increasingly promoted as a suitable alternative diagnostic bio-sample to blood, yet its role in respiratory disease is still to be elucidated.

Salivary levels of C-Reactive Protein (CRP), Procalcitonin (PCT) and Neutrophil Elastase (NE)... Read More about EVALUATION OF SALIVA BIOMARKERS AS INDICATORS OF HEALTH STATUS AND EXACERBATIONS IN COPD.

Risk of vascular events in patients with polymyalgia rheumatica. (2014)
Journal Article
Hancock, A. T., Mallen, C. D., Muller, S., Belcher, J., Roddy, E., Helliwell, T., & Hider, S. L. (2014). Risk of vascular events in patients with polymyalgia rheumatica. Canadian Medical Association Journal, 186(13), E495 - E501. https://doi.org/10.1503/cmaj.140266

BACKGROUND: Polymyalgia rheumatica is one of the most common inflammatory rheumatologic conditions in older adults. Other inflammatory rheumatologic disorders are associated with an excess risk of vascular disease. We investigated whether polymyalgia... Read More about Risk of vascular events in patients with polymyalgia rheumatica..