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The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions (2024)
Journal Article
Goh, R. S. J., Chong, B., Jayabaskaran, J., Jauhari, S. M., Chan, S. P., Kueh, M. T. W., Shankar, K., Li, H., Chin, Y. H., Kong, G., Anand, V. V., Chan, K. A., Sukmawati, I., Toh, S. A., Muthiah, M., Wang, J.-W., Tse, G., Mehta, A., Fong, A., Baskaran, L., …Chew, N. W. (2024). The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions. The Lancet Regional Health - Western Pacific, 49, Article 101138. https://doi.org/10.1016/j.lanwpc.2024.101138

Background
Given the rapidly growing burden of cardiovascular disease (CVD) in Asia, this study forecasts the CVD burden and associated risk factors in Asia from 2025 to 2050.

M... Read More about The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast analysis for East Asia, South Asia, South-East Asia, Central Asia, and high-income Asia Pacific regions.

133 Gender Differences in Mortality of Hospitalised Stroke Patients: A Systematic Review and Meta-Analysis (2024)
Presentation / Conference Contribution
Abdel-Fattah, A. R., Pana, T., Smith, T., Pasdar, Z., Aslam, M., Mamas, M., & Myint, P. 133 Gender Differences in Mortality of Hospitalised Stroke Patients: A Systematic Review and Meta-Analysis. Presented at ASiT Annual Conference 2024, Bournemouth, UK

Aim Gender differences in mortality after stroke remain unclear in the current literature. We therefore aimed to systematically review the gender differences in mortality up to five-years following ischaemic (IS) or haemorrhagic stroke(HS) to address... Read More about 133 Gender Differences in Mortality of Hospitalised Stroke Patients: A Systematic Review and Meta-Analysis.

Temporal trends of in-hospital mortality and its determinants following percutaneous coronary intervention in patients with acute coronary syndrome in England and Wales: A population-based study between 2006 and 2021. (2024)
Journal Article
Ayayo, S. A., Kontopantelis, E., Martin, G. P., Zghebi, S. S., Taxiarchi, V. P., & Mamas, M. A. (2024). Temporal trends of in-hospital mortality and its determinants following percutaneous coronary intervention in patients with acute coronary syndrome in England and Wales: A population-based study between 2006 and 2021. International Journal of Cardiology, 412, Article 132334. https://doi.org/10.1016/j.ijcard.2024.132334

There is limited data around drivers of changes in mortality over time. We aimed to examine the temporal changes in mortality and understand its determinants over time. 743,149 PCI procedures for patients from the British Cardiovascular Intervention... Read More about Temporal trends of in-hospital mortality and its determinants following percutaneous coronary intervention in patients with acute coronary syndrome in England and Wales: A population-based study between 2006 and 2021..

Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer (2024)
Journal Article
Ajabnoor, A. M., Zghebi, S. S., Parisi, R., Ashcroft, D. M., Faivre-Finn, C., Mamas, M. A., & Kontopantelis, E. (2024). Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer. European Heart Journal Open, 4(4), Article oeae053. https://doi.org/10.1093/ehjopen/oeae053

Aims: To compare the predictive performance of CHA2DS2-VASc and HAS-BLED scores in atrial fibrillation (AF) patients with and without cancer. Methods and results: Using data from the Clinical Practice Research Datalink in England, we performed a retr... Read More about Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer.

Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases (2024)
Journal Article
Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., …Coats, A. J. (in press). Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, https://doi.org/10.1002/ejhf.3347

The association between type 2 diabetes mellitus (T2DM) and heart failure (HF) has been firmly established; however, the entity of diabetic myocardial disorder (previously called diabetic cardiomyopathy) remains a matter of debate. Diabetic myocardia... Read More about Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases.

Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait‐Times and Clinical Consequences (2024)
Journal Article
Zaheer, A., Qiu, F., Manoragavan, R., Madan, M., Sud, M., Mamas, M. A., & Wijeysundera, H. C. (2024). Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait‐Times and Clinical Consequences. Journal of the American Heart Association, 13(12), https://doi.org/10.1161/jaha.123.032450

Background Transcatheter aortic valve replacement (TAVR) has become the standard of care for severe aortic stenosis treatment. Exponential growth in demand has led to prolonged wait times and adverse patient outcomes. Social marginalization may contr... Read More about Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait‐Times and Clinical Consequences.

Addressing the Global Burden of Cardiovascular Disease in Women JACC State-of-the-Art Review (2024)
Journal Article
Vervoort, D., Wang, R., Li, G., Filbey, L., Maduka, O., Brewer, L. C., Mamas, M. A., Bahit, M. C., Ahmed, S. B., & Van Spall, H. G. (2024). Addressing the Global Burden of Cardiovascular Disease in Women JACC State-of-the-Art Review. Journal of the American College of Cardiology, 83(25), 2690-2707. https://doi.org/10.1016/j.jacc.2024.04.028

Cardiovascular diseases (CVDs) are responsible for approximately 35% of all deaths in women. In 2019, the global age-standardized CVD prevalence and mortality of women were 6,403 per 100,000 and 204 per 100,000, respectively. Althou... Read More about Addressing the Global Burden of Cardiovascular Disease in Women JACC State-of-the-Art Review.

OP0136 RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH GOUT STARTING URATE-LOWERING THERAPY WITH OR WITHOUT FLARE PROPHYLAXIS WITH COLCHICINE: AN EMULATED TARGET TRIAL USING ENGLISH PRIMARY-CARE, HOSPITALISATION, AND MORTALITY DATA (2024)
Journal Article
Cipolletta, E., Nakafero, G., Avery, A., Mamas, M., Tata, L., & Abhishek, A. (2025). OP0136 RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH GOUT STARTING URATE-LOWERING THERAPY WITH OR WITHOUT FLARE PROPHYLAXIS WITH COLCHICINE: AN EMULATED TARGET TRIAL USING ENGLISH PRIMARY-CARE, HOSPITALISATION, AND MORTALITY DATA. Annals of the Rheumatic Diseases, 83, 87-88. https://doi.org/10.1136/annrheumdis-2024-eular.1001

Background:
Gout flares are associated with cardiovascular events (CVEs). Clinical trials show that low-dose colchicine reduces the risk of CVEs in patients with atherosclerotic cardiovascular diseases [1,2]. An o... Read More about OP0136 RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH GOUT STARTING URATE-LOWERING THERAPY WITH OR WITHOUT FLARE PROPHYLAXIS WITH COLCHICINE: AN EMULATED TARGET TRIAL USING ENGLISH PRIMARY-CARE, HOSPITALISATION, AND MORTALITY DATA.

44 Impact of the danish comorbidity index for acute myocardial infarction score on 30-day unplanned readmission rates and causes in hospitalised patients with acute coronary syndrome (2024)
Presentation / Conference Contribution
Sokhal, B. S., Matetić, A., Marshall, M., Twohig, H., Shepherd, T., Mallen, C., & Mamas, M. (2024, June). 44 Impact of the danish comorbidity index for acute myocardial infarction score on 30-day unplanned readmission rates and causes in hospitalised patients with acute coronary syndrome. Paper presented at British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024, Manchester

Introduction This study aimed to investigate the association of the DANish CoMorbidity Index for Acute Myocardial Infarction (DANCAMI) score with the 30-day unplanned readmission rates and causes and in acute coronary syndrome (ACS) patients.

Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy (2024)
Journal Article
Diaz-Arocutipa, C., Moreno, G., Giráldez, M., Hernandez, A. V., Mamas, M. A., & Vicent, L. (2024). Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy. CJC Open, https://doi.org/10.1016/j.cjco.2024.05.013

Background
There is limited data examining potential sex-based disparities in the utilization and complications of septal reduction therapy (SRT) in patients with obstructive hypertrophic cardiomyopathy (HCM). Our aim was t... Read More about Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy.