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Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses (2019)
Journal Article
Watson, L., Loke, Y., Mallen, C., Mamas, M., Gulati, M., Kwok, C., …Wu, P. (2019). Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses. European Journal of Preventive Cardiology, 26(13), 1415-1429. https://doi.org/10.1177/2047487319843667

Aims
The optimal diet for cardiovascular health is controversial. The aim of this review is to summarize the highest level of evidence and rank the risk associated with each individual component of diet within its food group.

Methods and results... Read More about Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses.

Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial (2019)
Journal Article
Wu. (2019). Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial. The Lancet, 394(10204), 1181 - 1190. https://doi.org/10.1016/S0140-6736%2819%2931963-4

BACKGROUND: In women with late preterm pre-eclampsia, the optimal time to initiate delivery is unclear because limitation of maternal disease progression needs to be balanced against infant complications. The aim of this trial was to determine whethe... Read More about Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial.

Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics (2019)
Journal Article
Mamas, & Wu. (2019). Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics. Journal of Women's Health, 1037 - 1050. https://doi.org/10.1089/jwh.2018.7480

Globally, cardiovascular disease (CVD) is the most common cause of mortality in women accounting for one in three deaths. There remains an under recognition of CVD as well as a lack of awareness of risk in women. Promotion of CVD prevention is essent... Read More about Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics.

Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics (2019)
Journal Article
Mamas, & Wu. (2019). Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics. Journal of Women's Health, 1037-1050. https://doi.org/10.1089/jwh.2018.7480

Globally, cardiovascular disease is the most common cause of mortality in women accounting for 1 in 3 deaths. There remains an under recognition of cardiovascular disease as well as a lack of awareness of risk in women. Promotion of cardiovascular di... Read More about Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics.

Adenovirus-mediated transfer of shRNA against Elovl6 reduces the progression of hepatocellular carcinoma (2018)
Presentation / Conference
Shiau, A. . L., Su, Y. . C., Feng, Y. . H., Huang, Y. . S., Wu, P., & Wu, C. . L. (2018, October). Adenovirus-mediated transfer of shRNA against Elovl6 reduces the progression of hepatocellular carcinoma. Poster presented at Changing the Face of Modern Medicine: Stem Cell and Gene Therapy Organized Jointly by the European Society of Gene & Cell Therapy (ESGCT), International Society for Stem Cell Research (ISSCR) and the French Society of Gene and Cell Therapy (SFTCG), Lausanne, Switzerland

The elongation of long-chain fatty acids family member 6(Elovl6), a key enzyme in lipogenesis, catalyzes the elongation of saturated and monounsaturated fatty acids. Insulin resistance is associated with upregulation of Elovl6, which has been linkedt... Read More about Adenovirus-mediated transfer of shRNA against Elovl6 reduces the progression of hepatocellular carcinoma.

Adenovirus-mediated transfer of shRNA against Elovl6 reduces the progression of hepatocellular carcinoma (2018)
Presentation / Conference
Shiau, A. L., Su, Y. C., Feng, Y. H., Huang, Y. S., Wu, P., & Wu, C. L. (2018, October). Adenovirus-mediated transfer of shRNA against Elovl6 reduces the progression of hepatocellular carcinoma. Paper presented at Changing the Face of Modern Medicine: Stem Cell and Gene Therapy Organized Jointly by the European Society of Gene & Cell Therapy (ESGCT), International Society for Stem Cell Research (ISSCR) and the French Society of Gene and Cell Therapy (SFTCG), Lausanne, Switzerland

The Factor IX (FIX) gene therapy (BAX335) was produced in small-scale for hemophilia-B patients in clinical phase I/II. In the course of the internal BAX335 process development, the small-scale clinical product was compared to BAX335 developed using... Read More about Adenovirus-mediated transfer of shRNA against Elovl6 reduces the progression of hepatocellular carcinoma.

CHARACTERIZATION AND DIFFERENTIATION OF PLACENTA-DERIVED MESENCHYMAL STEM CELLS FROM GDM WOMEN INTO INSULIN PRODUCING CELLS FOR PERSONALISED MEDICINE (2018)
Presentation / Conference
Chen, L., Merkhan, M., Forsyth, N. R., & Wu, P. (2018, September). CHARACTERIZATION AND DIFFERENTIATION OF PLACENTA-DERIVED MESENCHYMAL STEM CELLS FROM GDM WOMEN INTO INSULIN PRODUCING CELLS FOR PERSONALISED MEDICINE. Poster presented at International Federation of Placenta Associations Meeting, Tokyo, Japan

Objectives: Chorionic and amniotic MSCs (CMSCs/AMSCs) are derived
from different sides of placental membrane. Women with a history of
gestational diabetes mellitus have a high risk of developing subsequent
diabetes. As cell therapy is a promising... Read More about CHARACTERIZATION AND DIFFERENTIATION OF PLACENTA-DERIVED MESENCHYMAL STEM CELLS FROM GDM WOMEN INTO INSULIN PRODUCING CELLS FOR PERSONALISED MEDICINE.

Preterm delivery and maternal cardiovascular disease future risk: A systematic review and meta-analysis (2018)
Presentation / Conference
Wu, P., Gulati, M., Kwok, C., Wong, C., Narain, A., O'Brien, S., …Mamas, M. (2018, April). Preterm delivery and maternal cardiovascular disease future risk: A systematic review and meta-analysis. Poster presented at British Maternal & Fetal Medicine Society (BMFMS) 20th Annual Conference 2018, Brighton, UK

Objectives

We aimed to systematically evaluate and summarise the evidence on the relationship between preterm birth (<37 weeks of gestational age) and maternal cardiovascular diseases future risk.

Design

Systematic review and meta-analysis o...