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Nanofibrous scaffolds supporting optimal central nervous system regeneration: an evidence-based review (2015)
Journal Article
Yang, Y. (2015). Nanofibrous scaffolds supporting optimal central nervous system regeneration: an evidence-based review. Journal of Neurorestoratology, 123 - 131. https://doi.org/10.2147/JN.S70337

Restoration of function following damage to the central nervous system (CNS) is severely restricted by several factors. These include the hindrance of axonal regeneration imposed by glial scars resulting from inflammatory response to damage, and limi... Read More about Nanofibrous scaffolds supporting optimal central nervous system regeneration: an evidence-based review.

Self-renewal of human embryonic stem cells on defined synthetic electrospun nanofibers (2015)
Journal Article
Kumar, D., Dale, T. P., Yang, Y., & Forsyth, N. R. (2015). Self-renewal of human embryonic stem cells on defined synthetic electrospun nanofibers. Biomedical Materials, 10(6), Article 065017. https://doi.org/10.1088/1748-6041/10/6/065017

Human embryonic stem cells (hESCs) are conventionally expanded and maintained in vitro on biological substrates. Synthetic electrospun polymer nanofibers have the potential to act as non-biological substrates in the culture of hESCs. Three synthetic,... Read More about Self-renewal of human embryonic stem cells on defined synthetic electrospun nanofibers.

Image analysis and quantification of tissue scaffolds (2015)
Book Chapter
Yang, Y., & Wimpenny, I. (2015). Image analysis and quantification of tissue scaffolds. In Characterisation and Design of Tissue Scaffolds (201-223). Elsevier. https://doi.org/10.1016/b978-1-78242-087-3.00009-2

If you can measure something, then you can improve it. Measurement of the structural and functional parameters of tissue-engineering scaffolds is important in the context of better scaffold design, regulation of cellular activities, and the predictio... Read More about Image analysis and quantification of tissue scaffolds.

First results of LHCD experiments with 4.6 GHz system toward steady-state plasma in EAST (2015)
Journal Article
Liu, F., Ding, B., Li, J., Wan, B., Shan, J., Wang, M., …the EAST Team. (2015). First results of LHCD experiments with 4.6 GHz system toward steady-state plasma in EAST. Nuclear Fusion, 55(12), 123022. https://doi.org/10.1088/0029-5515/55/12/123022

A 4.6 GHz lower-hybrid current drive (LHCD) system has been firstly commissioned in EAST in the 2014 campaign. The first LHCD results with 4.6 GHz show that LHW can be coupled to plasma with a low reflection coefficient, drive plasma current and plas... Read More about First results of LHCD experiments with 4.6 GHz system toward steady-state plasma in EAST.

Nano-colloid printing of functionalised PLA-b-PEO copolymers: Tailoring the surface pattern of adhesive motif and its effect on cell attachment (2015)
Journal Article
Yang. (2015). Nano-colloid printing of functionalised PLA-b-PEO copolymers: Tailoring the surface pattern of adhesive motif and its effect on cell attachment

n this study, we investigate the preparation of surface pattern of functional groups on poly(lactide) (PLA) surfaces through the controlled deposition of core-shell self-assemblies based on functionalized PLA-b-PEO amphiphilic block copolymers from s... Read More about Nano-colloid printing of functionalised PLA-b-PEO copolymers: Tailoring the surface pattern of adhesive motif and its effect on cell attachment.

Fluorescent Monitoring of Poly(lactic-co-glycolic Acid) Degradation and Extracellular Matrix Turnover of Engineered Tissue Constructs (2015)
Presentation / Conference
Bardsley, K., El Haj, A., & Yang, Y. (2015, September). Fluorescent Monitoring of Poly(lactic-co-glycolic Acid) Degradation and Extracellular Matrix Turnover of Engineered Tissue Constructs. Paper presented at 2015 4th TERMIS World Congress, Boston, Massachusetts, USA

Development of fluorescent tagging techniques for inert polymers is an advantageous tool for monitoring biomaterial degradation online. Here we present a protocol for the fluorescent tagging of poly(lactic-co-glycolic acid) (PLGA) which allows for ac... Read More about Fluorescent Monitoring of Poly(lactic-co-glycolic Acid) Degradation and Extracellular Matrix Turnover of Engineered Tissue Constructs.

Multi-functional PLGA Scaffolds For Vascularization In Bone Tissue Constructs (2015)
Presentation / Conference
Yang, Y., & Lyu, L. (2015, September). Multi-functional PLGA Scaffolds For Vascularization In Bone Tissue Constructs

In our previous work, a new technique in which electrospun nanofibers were rolled into multilayered-rod-like 3D scaffolds has been used in rabbit radius regeneration in vivo. This has been highly successful in bone formation. However these scaffolds... Read More about Multi-functional PLGA Scaffolds For Vascularization In Bone Tissue Constructs.

Preparation and analysis of a new bioorganic metallic material (2015)
Journal Article
Yang. (2015). Preparation and analysis of a new bioorganic metallic material. RSC advances, 78030 -78037. https://doi.org/10.1039/c5ra16340d

Biofouling on metal surfaces is one of the main reasons for increased ship drag. Many methods have already been used to reduce or remove it with moderate success. In this study, a synthetic peptide has been utilized to react with 304 stainless steel... Read More about Preparation and analysis of a new bioorganic metallic material.

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow (2015)
Journal Article
Roffe, Yang, & Naire. (2015). In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow. Journal of NeuroInterventional Surgery, 969-972. https://doi.org/10.1136/neurintsurg-2015-011909

BACKGROUND: Mechanical thrombectomy with stent retriever devices is associated with significantly better outcomes than thrombolysis alone in the treatment of acute ischemic stroke. Thrombus aspiration achieves high patency rates, but clinical outcome... Read More about In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow.